(29 nodes) TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain network (Arabidopsis thaliana)

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	MQK4.18	Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase 2; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity). (166 aa)
	CAN2	Staphylococcal-like nuclease CAN2; Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond. Possesses activity toward the single-stranded DNA, double-stranded DNA and RNA. May be involved in genomic DNA degradation during programmed cell death. (332 aa)
	T7B11.13	TolB protein-like protein. (701 aa)
	CAN1	Staphylococcal-like nuclease CAN1; Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond. Possesses activity toward the single-stranded DNA, double-stranded DNA and RNA. May be involved in genomic DNA degradation during programmed cell death. (323 aa)
	SHOC1	Protein SHORTAGE IN CHIASMATA 1; Essential for the formation of class I meiotic crossovers. (1594 aa)
	F18E5.200	Oxidoreductase, zinc-binding dehydrogenase family protein. (325 aa)
	T27I1.12	Protein prenylyltransferase superfamily protein. (420 aa)
	ISI1	Impaired sucrose induction 1. (305 aa)
	RGTB1	Geranylgeranyl transferase type-2 subunit beta 1; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. Involved in the geranylgeranylation of RABA2A. In vitro, can prenylate PGGTI targets with the C-terminal sequence Cys-aliphatic- aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C-terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the beta subuni [...] (321 aa)
	RFS1	Probable galactinol--sucrose galactosyltransferase 1; Transglycosidase operating by a ping-pong reaction mechanism. Involved in the synthesis of raffinose, a major soluble carbohydrate in seeds, roots and tubers (By similarity). (754 aa)
	SHH2	Protein SAWADEE HOMEODOMAIN HOMOLOG 2; May play a role in the recruitment of Pol IV to genomic regions associated with K9 methylated histone H3 that are targets for RdDM. (348 aa)
	RFS6	Probable galactinol--sucrose galactosyltransferase 6; Transglycosidase operating by a ping-pong reaction mechanism. Involved in the synthesis of raffinose, a major soluble carbohydrate in seeds, roots and tubers (By similarity). (749 aa)
	RGTA1	Geranylgeranyl transferase type-2 subunit alpha 1; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. In vitro, can prenylate PGGTI targets with the C-terminal Cys-aliphatic-aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C-terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the alpha subunit is associated with a beta subunit (RGTB1 or RGTB2). (678 aa)
	RFS2	Probable galactinol--sucrose galactosyltransferase 2; Transglycosidase operating by a ping-pong reaction mechanism. Involved in the synthesis of raffinose, a major soluble carbohydrate in seeds, roots and tubers (By similarity); Belongs to the glycosyl hydrolases 36 family. (773 aa)
	NDL2	Protein NDL2; Involved in a signaling pathway that modulates root auxin transport and auxin gradients. Acts partially by positively regulating the auxin carrier PIN2 and AUX1. Acts, together with GB1 as positive regulator of meristem initiation and branching. GB1 and NDL2 positively regulate basipetal inflorescence auxin transport and modulate MAX2 expression in shoots, which regulates organ and lateral meristem formation by the establishment and maintenance of auxin gradients. (344 aa)
	K24C1.7	Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase 3; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity). (166 aa)
	RGTA2	Geranylgeranyl transferase type-2 subunit alpha 2; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2 (By similarity). Does not seem to be a functional Rab-GGT alpha subunit in vitro. (687 aa)
	NDL1	Protein NDL1; Interacts with the heterotrimeric G protein beta subunit GB1 and plays an significant role in GB1-dependent regulation of lateral root formation. Involved in a signaling pathway that modulates root auxin transport and auxin gradients. Acts partially by positively regulating the auxin carrier PIN2 and AUX1. Acts, together with GB1 as positive regulator of meristem initiation and branching. GB1 and NDL1 positively regulate basipetal inflorescence auxin transport and modulate MAX2 expression in shoots, which regulates organ and lateral meristem formation by the establishment [...] (346 aa)
	RFS5	Probable galactinol--sucrose galactosyltransferase 5; Transglycosidase operating by a ping-pong reaction mechanism. Involved in the synthesis of raffinose, a major soluble carbohydrate in seeds, roots and tubers (By similarity); Belongs to the glycosyl hydrolases 36 family. (783 aa)
	RGTB2	Geranylgeranyl transferase type-2 subunit beta 2; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. In vitro, can prenylate PGGTI targets with the C-terminal sequence Cys-aliphatic-aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C- terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the beta subunit is associated with the alpha subunit RGTA1. (317 aa)
	Q9LK96_ARATH	GroES-like zinc-binding alcohol dehydrogenase family protein. (366 aa)
	T5P19_110	GroES-like zinc-binding alcohol dehydrogenase family protein. (348 aa)
	F13E7.29	Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase 1; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity). (166 aa)
	T16L4.30	Nucleophosmin. (306 aa)
	CEQORH	Chloroplast envelope quinone oxidoreductase homolog; NADPH-dependent alpha,beta-unsaturated oxoene reductase reducing the double bond of medium-chain (C9) to long-chain (C18) reactive electrophile species deriving from poly-unsaturated fatty acid peroxides. The best substrates are 13-lipoxygenase-derived gamma- ketols, but is unable to reduce the double bond of short-chain alkenals and alkenones such as acrolein, crotonaldehyde, 3-buten-2-one, 4-hexen- 3-one and trans-2-hexenal, or quinones such as duroquinone, decylubiquinone, coenzyme Q0, menadione, menaquinone and phylloquinone. Can [...] (329 aa)
	F8K7.10	DPP6 N-terminal domain-like protein. (706 aa)
	F8K7.9	DPP6 amino-terminal domain protein. (703 aa)
	AOR	NADPH-dependent alkenal/one oxidoreductase, chloroplastic; Reduces the double bond in short-chain unsaturated carbonyls. Acts preferentially on alpha,beta-unsaturated ketones rather on alpha,beta-unsaturated aldehydes. Has no activity with (E)-2-hexenal and (E)-2-pentenal. Contributes to detoxify stromal reactive carbonyls produced under oxidative stress. Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. (386 aa)
	NDL3	Protein NDL3; Involved in a signaling pathway that modulates root auxin transport and auxin gradients. Acts partially by positively regulating the auxin carrier PIN2 and AUX1. Acts, together with GB1 as positive regulator of meristem initiation and branching. GB1 and NDL3 positively regulate basipetal inflorescence auxin transport and modulate MAX2 expression in shoots, which regulates organ and lateral meristem formation by the establishment and maintenance of auxin gradients. (347 aa)

Your Current Organism:

Arabidopsis thaliana

NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ISI1	RFS1	Q84J43	Q84VX0	Impaired sucrose induction 1.	Probable galactinol--sucrose galactosyltransferase 1; Transglycosidase operating by a ping-pong reaction mechanism. Involved in the synthesis of raffinose, a major soluble carbohydrate in seeds, roots and tubers (By similarity).	0.400
RFS1	ISI1	Q84VX0	Q84J43	Probable galactinol--sucrose galactosyltransferase 1; Transglycosidase operating by a ping-pong reaction mechanism. Involved in the synthesis of raffinose, a major soluble carbohydrate in seeds, roots and tubers (By similarity).	Impaired sucrose induction 1.	0.400
RGTA1	RGTA2	Q8VYB7	Q9FJ32	Geranylgeranyl transferase type-2 subunit alpha 1; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. In vitro, can prenylate PGGTI targets with the C-terminal Cys-aliphatic-aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C-terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the alpha subunit is associated with a beta subunit (RGTB1 or RGTB2).	Geranylgeranyl transferase type-2 subunit alpha 2; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2 (By similarity). Does not seem to be a functional Rab-GGT alpha subunit in vitro.	0.561
RGTA1	RGTB1	Q8VYB7	Q84J75	Geranylgeranyl transferase type-2 subunit alpha 1; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. In vitro, can prenylate PGGTI targets with the C-terminal Cys-aliphatic-aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C-terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the alpha subunit is associated with a beta subunit (RGTB1 or RGTB2).	Geranylgeranyl transferase type-2 subunit beta 1; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. Involved in the geranylgeranylation of RABA2A. In vitro, can prenylate PGGTI targets with the C-terminal sequence Cys-aliphatic- aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C-terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the beta subuni [...]	0.999
RGTA1	RGTB2	Q8VYB7	Q9LHL5	Geranylgeranyl transferase type-2 subunit alpha 1; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. In vitro, can prenylate PGGTI targets with the C-terminal Cys-aliphatic-aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C-terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the alpha subunit is associated with a beta subunit (RGTB1 or RGTB2).	Geranylgeranyl transferase type-2 subunit beta 2; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. In vitro, can prenylate PGGTI targets with the C-terminal sequence Cys-aliphatic-aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C- terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the beta subunit is associated with the alpha subunit RGTA1.	0.999
RGTA1	T27I1.12	Q8VYB7	O80601	Geranylgeranyl transferase type-2 subunit alpha 1; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. In vitro, can prenylate PGGTI targets with the C-terminal Cys-aliphatic-aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C-terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the alpha subunit is associated with a beta subunit (RGTB1 or RGTB2).	Protein prenylyltransferase superfamily protein.	0.823
RGTA2	RGTA1	Q9FJ32	Q8VYB7	Geranylgeranyl transferase type-2 subunit alpha 2; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2 (By similarity). Does not seem to be a functional Rab-GGT alpha subunit in vitro.	Geranylgeranyl transferase type-2 subunit alpha 1; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. In vitro, can prenylate PGGTI targets with the C-terminal Cys-aliphatic-aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C-terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the alpha subunit is associated with a beta subunit (RGTB1 or RGTB2).	0.561
RGTA2	RGTB1	Q9FJ32	Q84J75	Geranylgeranyl transferase type-2 subunit alpha 2; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2 (By similarity). Does not seem to be a functional Rab-GGT alpha subunit in vitro.	Geranylgeranyl transferase type-2 subunit beta 1; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. Involved in the geranylgeranylation of RABA2A. In vitro, can prenylate PGGTI targets with the C-terminal sequence Cys-aliphatic- aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C-terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the beta subuni [...]	0.998
RGTA2	RGTB2	Q9FJ32	Q9LHL5	Geranylgeranyl transferase type-2 subunit alpha 2; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2 (By similarity). Does not seem to be a functional Rab-GGT alpha subunit in vitro.	Geranylgeranyl transferase type-2 subunit beta 2; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. In vitro, can prenylate PGGTI targets with the C-terminal sequence Cys-aliphatic-aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C- terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the beta subunit is associated with the alpha subunit RGTA1.	0.998
RGTB1	RGTA1	Q84J75	Q8VYB7	Geranylgeranyl transferase type-2 subunit beta 1; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. Involved in the geranylgeranylation of RABA2A. In vitro, can prenylate PGGTI targets with the C-terminal sequence Cys-aliphatic- aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C-terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the beta subuni [...]	Geranylgeranyl transferase type-2 subunit alpha 1; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. In vitro, can prenylate PGGTI targets with the C-terminal Cys-aliphatic-aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C-terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the alpha subunit is associated with a beta subunit (RGTB1 or RGTB2).	0.999
RGTB1	RGTA2	Q84J75	Q9FJ32	Geranylgeranyl transferase type-2 subunit beta 1; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. Involved in the geranylgeranylation of RABA2A. In vitro, can prenylate PGGTI targets with the C-terminal sequence Cys-aliphatic- aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C-terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the beta subuni [...]	Geranylgeranyl transferase type-2 subunit alpha 2; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2 (By similarity). Does not seem to be a functional Rab-GGT alpha subunit in vitro.	0.998
RGTB1	RGTB2	Q84J75	Q9LHL5	Geranylgeranyl transferase type-2 subunit beta 1; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. Involved in the geranylgeranylation of RABA2A. In vitro, can prenylate PGGTI targets with the C-terminal sequence Cys-aliphatic- aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C-terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the beta subuni [...]	Geranylgeranyl transferase type-2 subunit beta 2; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. In vitro, can prenylate PGGTI targets with the C-terminal sequence Cys-aliphatic-aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C- terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the beta subunit is associated with the alpha subunit RGTA1.	0.908
RGTB1	T27I1.12	Q84J75	O80601	Geranylgeranyl transferase type-2 subunit beta 1; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. Involved in the geranylgeranylation of RABA2A. In vitro, can prenylate PGGTI targets with the C-terminal sequence Cys-aliphatic- aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C-terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the beta subuni [...]	Protein prenylyltransferase superfamily protein.	0.990
RGTB2	RGTA1	Q9LHL5	Q8VYB7	Geranylgeranyl transferase type-2 subunit beta 2; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. In vitro, can prenylate PGGTI targets with the C-terminal sequence Cys-aliphatic-aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C- terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the beta subunit is associated with the alpha subunit RGTA1.	Geranylgeranyl transferase type-2 subunit alpha 1; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. In vitro, can prenylate PGGTI targets with the C-terminal Cys-aliphatic-aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C-terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the alpha subunit is associated with a beta subunit (RGTB1 or RGTB2).	0.999
RGTB2	RGTA2	Q9LHL5	Q9FJ32	Geranylgeranyl transferase type-2 subunit beta 2; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. In vitro, can prenylate PGGTI targets with the C-terminal sequence Cys-aliphatic-aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C- terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the beta subunit is associated with the alpha subunit RGTA1.	Geranylgeranyl transferase type-2 subunit alpha 2; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2 (By similarity). Does not seem to be a functional Rab-GGT alpha subunit in vitro.	0.998
RGTB2	RGTB1	Q9LHL5	Q84J75	Geranylgeranyl transferase type-2 subunit beta 2; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. In vitro, can prenylate PGGTI targets with the C-terminal sequence Cys-aliphatic-aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C- terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the beta subunit is associated with the alpha subunit RGTA1.	Geranylgeranyl transferase type-2 subunit beta 1; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. Involved in the geranylgeranylation of RABA2A. In vitro, can prenylate PGGTI targets with the C-terminal sequence Cys-aliphatic- aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C-terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the beta subuni [...]	0.908
RGTB2	T27I1.12	Q9LHL5	O80601	Geranylgeranyl transferase type-2 subunit beta 2; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. In vitro, can prenylate PGGTI targets with the C-terminal sequence Cys-aliphatic-aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C- terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the beta subunit is associated with the alpha subunit RGTA1.	Protein prenylyltransferase superfamily protein.	0.951
T27I1.12	RGTA1	O80601	Q8VYB7	Protein prenylyltransferase superfamily protein.	Geranylgeranyl transferase type-2 subunit alpha 1; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. In vitro, can prenylate PGGTI targets with the C-terminal Cys-aliphatic-aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C-terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the alpha subunit is associated with a beta subunit (RGTB1 or RGTB2).	0.823
T27I1.12	RGTB1	O80601	Q84J75	Protein prenylyltransferase superfamily protein.	Geranylgeranyl transferase type-2 subunit beta 1; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. Involved in the geranylgeranylation of RABA2A. In vitro, can prenylate PGGTI targets with the C-terminal sequence Cys-aliphatic- aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C-terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the beta subuni [...]	0.990
T27I1.12	RGTB2	O80601	Q9LHL5	Protein prenylyltransferase superfamily protein.	Geranylgeranyl transferase type-2 subunit beta 2; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2. In vitro, can prenylate PGGTI targets with the C-terminal sequence Cys-aliphatic-aliphatic-X (CaaX) with leucine in the terminal position. Substrates with the C- terminal sequence -CSIL such as ARAC11/ROP1 or GG2/AGG2 are prenylated independently of REP and when the beta subunit is associated with the alpha subunit RGTA1.	0.951