STRINGSTRING
A0A1I9LQI3 A0A1I9LQI3 A0A1I9LT28 A0A1I9LT28 A0A1P8ARQ6 A0A1P8ARQ6 JHS1 JHS1 PSF1 PSF1 A0A1P8B3C0 A0A1P8B3C0 MTI20.21 MTI20.21 A0A1P8BD70 A0A1P8BD70 APC6 APC6 NAC014 NAC014 POLA2 POLA2 POL2A POL2A F14L17.24 F14L17.24 F4HWA5_ARATH F4HWA5_ARATH F4HXC5_ARATH F4HXC5_ARATH F28J9.5 F28J9.5 F27J15.5 F27J15.5 F13F21.31 F13F21.31 T23E23.25 T23E23.25 MCM9 MCM9 POL2B POL2B F4IHC4_ARATH F4IHC4_ARATH F4IXH9_ARATH F4IXH9_ARATH F4JA83_ARATH F4JA83_ARATH PA200 PA200 T13O15.5 T13O15.5 F4JFC6_ARATH F4JFC6_ARATH BPS3 BPS3 NTL9 NTL9 F28A21.230 F28A21.230 F22K18.10 F22K18.10 RPA1E RPA1E TERC TERC POLA3 POLA3 MCM6 MCM6 MRA19.13 MRA19.13 RPT5B RPT5B PBB1 PBB1 PAF2 PAF2 PBD1 PBD1 PAG1 PAG1 PBE1 PBE1 RPN8A RPN8A PAD2 PAD2 PBD2 PBD2 POLD2 POLD2 RPN2A RPN2A STI STI FEN1 FEN1 APC4 APC4 ANAC023 ANAC023 T13D8.18 T13D8.18 T13D8.21 T13D8.21 NAC024 NAC024 T13D8.25 T13D8.25 MCM5 MCM5 PAE1-2 PAE1-2 PBC2 PBC2 BPS2 BPS2 CDC6 CDC6 RCA RCA PAD1 PAD1 PAF1 PAF1 MCM7 MCM7 RPN10 RPN10 RPS27AB RPS27AB RPS27AC RPS27AC RPS27AA RPS27AA Q058G7_ARATH Q058G7_ARATH CDC27A CDC27A MCM4 MCM4 POLD4 POLD4 T4C15.5 T4C15.5 ORC2 ORC2 Q3E931_ARATH Q3E931_ARATH PAE2-2 PAE2-2 LIG1 LIG1 DPB2 DPB2 T1N15.15 T1N15.15 ORC3 ORC3 ORC5 ORC5 ORC4 ORC4 TTN10 TTN10 SLD5 SLD5 ORC1A ORC1A PBG1 PBG1 PBB2 PBB2 MWD22.2 MWD22.2 EMB2813 EMB2813 NAC074 NAC074 RPN9B RPN9B APC5 APC5 APC2 APC2 UBC20 UBC20 PBA1 PBA1 CDC27B CDC27B RPN9A RPN9A RFC3 RFC3 APC7 APC7 CDC6B CDC6B RFC4 RFC4 RPT6B RPT6B NAC089 NAC089 F3N23.32 F3N23.32 RFC1 RFC1 RPT6A RPT6A RPN8B RPN8B GINS2 GINS2 T22A15.5 T22A15.5 F14G24.22 F14G24.22 RFC2 RFC2 T5M16.21 T5M16.21 RFC5 RFC5 UBC22 UBC22 APC1 APC1 POLA POLA RPA1C RPA1C RPN12B RPN12B MCM3 MCM3 RPA1D RPA1D T14P4.13 T14P4.13 F12A21.25 F12A21.25 Q9LH38_ARATH Q9LH38_ARATH PBE2 PBE2 UBC19 UBC19 BPS1 BPS1 GEN1 GEN1 MCM2 MCM2 POLD1 POLD1 CDT1B CDT1B GEN2 GEN2 F5K20_270 F5K20_270 PCNA PCNA NAC049 NAC049 APC11 APC11 RPT4B RPT4B RPN2B RPN2B F3F19.7 F3F19.7 NAC062 NAC062 RPA1B RPA1B RPT5A RPT5A RPT4A RPT4A RPT3-2 RPT3-2 MCM8 MCM8 RPN12A RPN12A CDT1A CDT1A RPA1A RPA1A RPT2B RPT2B RPT1B RPT1B RPT1A RPT1A APC8 APC8 ORC1B ORC1B RPT2A RPT2A PBC1 PBC1 NTL8 NTL8 NF-YB11 NF-YB11 ORC6 ORC6 PCNA2 PCNA2
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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A0A1I9LQI3Replication protein A1. (177 aa)
A0A1I9LT28Uncharacterized protein. (248 aa)
A0A1P8ARQ6Uncharacterized protein. (1041 aa)
JHS1DNA replication ATP-dependent helicase/nuclease JHS1; Essential protein required during embryogenesis. Key enzyme involved in DNA replication and damage repair, shoot apical meristem (SAM) maintenance, and development. Involved in Okazaki fragments processing. Possesses different enzymatic activities, such as single-stranded DNA (ssDNA)- dependent ATPase, 5'-3' helicase and endonuclease activities. While the ATPase and endonuclease activities are well-defined and play a key role in Okazaki fragments processing and DSB repair, the 5'-3' DNA helicase activity is atypical: it cannot load [...] (1331 aa)
PSF1Partner of SLD five 1. (207 aa)
A0A1P8B3C0Replication-like protein. (139 aa)
MTI20.2126S proteasome regulatory subunit. (256 aa)
A0A1P8BD70Nucleic acid-binding, OB-fold-like protein. (192 aa)
APC6Anaphase-promoting complex subunit 6; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of endor [...] (543 aa)
NAC014NAC domain-containing protein 14; Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). (652 aa)
POLA2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (620 aa)
POL2ADNA polymerase epsilon catalytic subunit A; DNA polymerase II, which participates in chromosomal DNA replication. Required for the timing and determination of cell fate during plant embryogenesis and root pole development, by promoting cell cycle and cell type patterning. Necessary for proper shoot (SAM) and root apical meristem (RAM) functions. Involved in maintaining epigenetic states, controlling hypersensitive response (HR), and mediating abscisic acid (ABA) signaling. Required for flowering repression through a mechanism involving epigenetic gene silencing. May participate in proc [...] (2161 aa)
F14L17.24Protein STICHEL-like 1. (1116 aa)
F4HWA5_ARATHE3 ubiquitin ligase. (170 aa)
F4HXC5_ARATHF-box protein. (243 aa)
F28J9.5Nucleic acid-binding proteins superfamily. (351 aa)
F27J15.5Serine/threonine-protein kinase ATG1t; Serine/threonine protein kinase involved in autophagy. The ATG1-ATG13 protein kinase complex regulates downstream events required for autophagosome enclosure and/or vacuolar delivery. (408 aa)
F13F21.31DNA ligase. (657 aa)
T23E23.25RNase H domain-containing protein. (353 aa)
MCM9Probable DNA helicase MCM9; Probable DNA helicase that may play a role in DNA repair during meiosis. (646 aa)
POL2BDNA polymerase epsilon catalytic subunit B; DNA polymerase II, which participates in chromosomal DNA replication (By similarity). Involved in the determination of cell fate during plant embryogenesis. Contributes to the flowering time repression. (2138 aa)
F4IHC4_ARATHNucleic acid-binding, OB-fold-like protein. (532 aa)
F4IXH9_ARATHARM repeat superfamily protein. (551 aa)
F4JA83_ARATHNucleic acid-binding proteins superfamily. (309 aa)
PA200Proteasome activator subunit 4; Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin- independent degradation of core histones during DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. involved in DNA d [...] (1811 aa)
T13O15.5Polynucleotidyl transferase, ribonuclease H-like superfamily protein. (294 aa)
F4JFC6_ARATHBPS1-like protein. (316 aa)
BPS3BPS1-like protein. (348 aa)
NTL9Protein NTM1-like 9; Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). Calmodulin-regulated transcriptional repressor. Binds several synthetic promoters with randomly selected binding sites. Functions synergistically with SNI1 as negative regulator of pathogen-induced PR1 expression and basal resistance to a virulent strain of P.syringae. Binds directly to the promoter of the PR1 gene. Acts as positive regulator of innate immunity. Involved in the effector-triggered immunity (ETI) induction of immunity-related gene expression [...] (512 aa)
F28A21.230Protein STICHEL-like 3; Belongs to the DnaX/STICHEL family. (1097 aa)
F22K18.10Protein STICHEL-like 2; Belongs to the DnaX/STICHEL family. (857 aa)
RPA1EReplication protein A 70 kDa DNA-binding subunit E; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (By similarity). (784 aa)
TERCThylakoid membrane protein TERC, chloroplastic; Integral thylakoid membrane protein that plays a crucial role in thylakoid membrane biogenesis and thylakoid formation in early chloroplast development. Is essential for de novo synthesis of photosystem II (PSII) core proteins and required for efficient insertion of thylakoid membrane proteins, presumably via interaction with ALB3. May assist synthesis of thylakoid membrane proteins at the membrane insertion step. (384 aa)
POLA3DNA primase; Belongs to the eukaryotic-type primase small subunit family. (451 aa)
MCM6DNA replication licensing factor MCM6; Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells. (831 aa)
MRA19.13Protein STICHEL-like 4. (966 aa)
RPT5B26S proteasome regulatory subunit 6A homolog B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (423 aa)
PBB1Proteasome subunit beta type-7-A; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1B family. (273 aa)
PAF2Proteasome subunit alpha type-1-B; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. May play a role in thiol biosynthesis and arsenic tolerance in association with PAF1/ARS5. (277 aa)
PBD1Proteasome subunit beta type-2-A; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1B family. (204 aa)
PAG1Proteasome subunit alpha type-3; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. (249 aa)
PBE1Proteasome subunit beta type-5-A; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1B family. (274 aa)
RPN8A26S proteasome non-ATPase regulatory subunit 7 homolog A; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (By similarity). Required for innate immunity. (308 aa)
PAD2Proteasome subunit alpha type-7-B; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1A family. (250 aa)
PBD2Proteasome subunit beta type-2-B; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1B family. (199 aa)
POLD2DNA polymerase delta small subunit; The function of the small subunit is not yet clear. (440 aa)
RPN2A26S proteasome non-ATPase regulatory subunit 1 homolog A; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (1004 aa)
STIProtein STICHEL; Acts as a key regulator of trichome branching through an endoreduplication-independent pathway. (1218 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (383 aa)
APC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of endor [...] (777 aa)
ANAC023NAC domain containing protein 23. (347 aa)
T13D8.18NAC (No Apical Meristem) domain transcriptional regulator superfamily protein. (322 aa)
T13D8.21NAC (No Apical Meristem) domain transcriptional regulator superfamily protein. (371 aa)
NAC024NAC domain containing protein 24. (320 aa)
T13D8.25NAC (No Apical Meristem) domain transcriptional regulator superfamily protein. (318 aa)
MCM5DNA replication licensing factor MCM5; Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells. (727 aa)
PAE1-2Proteasome subunit alpha type-5-A; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1A family. (237 aa)
PBC2Proteasome subunit beta type-3-B; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1B family. (204 aa)
BPS2BPS1-like protein. (347 aa)
CDC6Cell division control protein 6 homolog; May be involved in the initiation of DNA replication. May play a role in endoreduplication. Could act as one of the factors that contributes to maintain endoreduplication competence. Belongs to the CDC6/cdc18 family. (539 aa)
RCARibulose bisphosphate carboxylase/oxygenase activase, chloroplastic; Activation of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase; EC 4.1.1.39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure. (474 aa)
PAD1Proteasome subunit alpha type-7-A; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the association of the SCF(TIR1) E3 ubiquitin ligase complex with the proteasome. (250 aa)
PAF1Proteasome subunit alpha type-1-A; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Negatively regulates thiol biosynthesis and arsenic tolerance. (278 aa)
MCM7DNA replication licensing factor MCM7; Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells (By similarity). Required for megagametophyte and embryo development. (716 aa)
RPN1026S proteasome non-ATPase regulatory subunit 4 homolog; Plays a role in maintaining the structural integrity of the 19S regulatory particle (RP), subcomplex of the 26S proteasome. Plays a major role in both the direct and indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP). Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a potential docking subunit for both ubiquitin receptors RAD23s and [...] (386 aa)
RPS27ABUbiquitin-40S ribosomal protein S27a-2; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-11-linked is invol [...] (157 aa)
RPS27ACUbiquitin-40S ribosomal protein S27a-3; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-11-linked is invol [...] (157 aa)
RPS27AAUbiquitin-40S ribosomal protein S27a-1; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-11-linked is invol [...] (156 aa)
Q058G7_ARATHF-box family protein. (114 aa)
CDC27ACell division cycle protein 27 homolog A; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of e [...] (717 aa)
MCM4DNA replication licensing factor MCM4; Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells. (847 aa)
POLD4Polymerase delta 4. (124 aa)
T4C15.5F-box protein At2g35280. (163 aa)
ORC2Origin of replication complex subunit 2; Essential protein. Component of the origin recognition complex (ORC) that binds origins of replication. DNA- binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity). (363 aa)
Q3E931_ARATHAnaphase-promoting complex subunit 11 RING-H2 finger protein. (62 aa)
PAE2-2Proteasome subunit alpha type-5-B; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1A family. (237 aa)
LIG1DNA ligase 1; Essential protein. DNA ligase that seals nicks in double- stranded DNA during DNA replication, DNA recombination and DNA repair. Involved in repair of both single strand breaks (SSBs) and double strand breaks (DSBs). Required in the endosperm for embryogenesis, probably to repair DNA-breaks generated by DME. (790 aa)
DPB2DNA polymerase epsilon subunit B; As accessory component of DNA polymerase II participates in chromosomal DNA replication. Required for the timing and determination of cell fate during plant embryogenesis and root pole development, by promoting cell cycle and cell type patterning. Necessary for proper shoot (SAM) and root apical meristem (RAM) functions (By similarity). Is essential to promote the first divisions of the zygote. (526 aa)
T1N15.15Proteasome inhibitor-like protein. (175 aa)
ORC3Origin of replication complex subunit 3; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. (734 aa)
ORC5Origin of replication complex subunit 5; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication; Belongs to the ORC5 family. (534 aa)
ORC4Origin of replication complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (417 aa)
TTN10GINS complex protein. (185 aa)
SLD5DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (220 aa)
ORC1AOrigin of replication complex subunit 1A; Essential protein. Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication (By similarity). H3K4me3 effector that regulates positively the transcription of a subset of genes. Belongs to the ORC1 family. (809 aa)
PBG1Proteasome subunit beta type-4; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. (246 aa)
PBB2Proteasome subunit beta type-7-B; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. (274 aa)
MWD22.2RNase H family protein. (322 aa)
EMB2813Probable DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (454 aa)
NAC074NAC domain containing protein 74. (352 aa)
RPN9B26S proteasome non-ATPase regulatory subunit 13 homolog B; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (386 aa)
APC5Anaphase-promoting complex subunit 5; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of endor [...] (916 aa)
APC2Anaphase-promoting complex subunit 2; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of endor [...] (865 aa)
UBC20Ubiquitin-conjugating enzyme E2 20; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins; Belongs to the ubiquitin-conjugating enzyme family. (180 aa)
PBA1Proteasome subunit beta type-6; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. (233 aa)
CDC27BCell division cycle protein 27 homolog B; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of e [...] (744 aa)
RPN9A26S proteasome non-ATPase regulatory subunit 13 homolog A; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (386 aa)
RFC3Replication factor C subunit 3; May be involved in DNA replication and thus regulate cell proliferation. (354 aa)
APC7Anaphase-promoting complex subunit 7; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of endor [...] (558 aa)
CDC6BCell division control protein 6 homolog B; May be involved in the initiation of DNA replication. Belongs to the CDC6/cdc18 family. (505 aa)
RFC4Replication factor C subunit 4; May be involved in DNA replication and thus regulate cell proliferation; Belongs to the activator 1 small subunits family. (339 aa)
RPT6B26S proteasome regulatory subunit 8 homolog B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (419 aa)
NAC089NAC domain-containing protein 89; Transcription factor involved in plant cell division. (340 aa)
F3N23.32P-loop containing nucleoside triphosphate hydrolases superfamily protein. (432 aa)
RFC1Replication factor C subunit 1; Plays a role as mediator of transcriptional gene silencing (TGS), DNA replication, DNA repair, hypersensitive response (HR) and telomere length regulation. Is required in meiosis for DNA double- strand break (DSB) repair during meiotic homologous recombination. May participate in the RAD51-mediated recombination intermediate repair process. Is important for lagging strand synthesis. Promotes meiotic recombination via a specific pathway for crossovers (COs) that involves the formation of double Holliday Junction (dHJ) intermediates. (956 aa)
RPT6A26S proteasome regulatory subunit 8 homolog A; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (419 aa)
RPN8B26S proteasome non-ATPase regulatory subunit 7 homolog B; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (310 aa)
GINS2DNA replication complex GINS protein PSF2; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS2/PSF2 family. (210 aa)
T22A15.5F-box family protein. (80 aa)
F14G24.22Nucleic acid-binding, OB-fold-like protein. (566 aa)
RFC2Replication factor C subunit 2; May be involved in DNA replication and thus regulate cell proliferation. (333 aa)
T5M16.21P-loop containing nucleoside triphosphate hydrolases superfamily protein. (1151 aa)
RFC5Replication factor C subunit 5; Functions in cell replication and proliferation. May be involved in chromatin assembly and remodeling. Plays a role in the negative control of pathogenesis-related gene expression and systemic acquired resistance (SAR). (369 aa)
UBC22Ubiquitin-conjugating enzyme E2 22; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins; Belongs to the ubiquitin-conjugating enzyme family. (251 aa)
APC1Anaphase-promoting complex subunit 1; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of endor [...] (1678 aa)
POLADNA polymerase alpha catalytic subunit; Polymerase alpha in a complex with DNA primase is a replicative polymerase; Belongs to the DNA polymerase type-B family. (1524 aa)
RPA1CReplication protein A 70 kDa DNA-binding subunit C; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (By similarity). (853 aa)
RPN12BPutative 26S proteasome non-ATPase regulatory subunit 8 homolog B; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (233 aa)
MCM3DNA replication licensing factor MCM3; Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells. (776 aa)
RPA1DReplication protein A 70 kDa DNA-binding subunit D; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (By similarity). (629 aa)
T14P4.13T14P4.13 protein. (290 aa)
F12A21.25Putative F-box protein At1g67623. (296 aa)
Q9LH38_ARATHUncharacterized protein. (161 aa)
PBE2Proteasome subunit beta type-5-B; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1B family. (273 aa)
UBC19Ubiquitin-conjugating enzyme E2 19; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Part of the anaphase-promoting complex (APC). May have a key function during cell cycle and be involved in cyclin B1 degradation; Belongs to the ubiquitin-conjugating enzyme family. (181 aa)
BPS1Protein BPS1, chloroplastic; Required for normal root and shoot development. Prevents constitutive production of a root mobile carotenoid-derived signaling compound that is capable of arresting shoot and leaf development. (349 aa)
GEN1Flap endonuclease GEN-like 1; Endonuclease which cleaves flap structures at the junction between single-stranded DNA and double-stranded DNA; Belongs to the XPG/RAD2 endonuclease family. GEN subfamily. (599 aa)
MCM2DNA replication licensing factor MCM2; Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells. May play a crucial role in the control of de- differentiation and cell proliferation processes required for lateral root formation. Is essential for embryo development. Is involved in the geminivirus mungbean yellow mosaic virus (MYMV) DNA replication, presumably in conjunction with other host factors. (936 aa)
POLD1DNA polymerase delta catalytic subunit; This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. (1095 aa)
CDT1BCDT1-like protein b; Member of the pre-replication complex. Regulates endoreduplication. Involved in the coordination of cell and plastid division. (486 aa)
GEN2Flap endonuclease GEN-like 2; Belongs to the XPG/RAD2 endonuclease family. GEN subfamily. (600 aa)
F5K20_270Probable proteasome inhibitor; Could play an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome (By similarity); Belongs to the proteasome inhibitor PI31 family. (302 aa)
PCNAProliferating cellular nuclear antigen 1; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (263 aa)
NAC049NAC domain containing protein 49. (198 aa)
APC11Anaphase-promoting complex subunit 11; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of endo [...] (84 aa)
RPT4B26S proteasome regulatory subunit S10B homolog B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (399 aa)
RPN2B26S proteasome non-ATPase regulatory subunit 1 homolog B; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (1001 aa)
F3F19.7Proline-rich receptor-like kinase. (317 aa)
NAC062NAC domain-containing protein 62; Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). Transcriptional activator involved in response to cold stress. Mediates induction of pathogenesis-related (PR) genes independently of salicylic signaling in response to cold. Binds directly to the PR gene promoters and enhances plant resistance to pathogen infection, incorporating cold signals into pathogen resistance responses. Plays a regulatory role in abscisic acid (ABA)-mediated drought-resistance response. (469 aa)
RPA1BReplication protein A 70 kDa DNA-binding subunit B; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions (By similarity). Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (By similarity). (604 aa)
RPT5A26S proteasome regulatory subunit 6A homolog A; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. Plays a essential role in the gametophyte development. (424 aa)
RPT4A26S proteasome regulatory subunit 10B homolog A; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (399 aa)
RPT3-226S proteasome regulatory subunit 6B homolog; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (408 aa)
MCM8Probable DNA helicase MCM8; Probable DNA helicase that plays a role in meiotic double- strand break (DSB) repair, but seems not required for recombination with the homologous chromosome. May be involved with RAD51 in a backup pathway that repairs meiotic DSB without giving meiotic crossover, in parallel to the meiotic homologous recombination which relies on DMC1. Belongs to the MCM family. (801 aa)
RPN12A26S proteasome non-ATPase regulatory subunit 8 homolog A; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. May help to control the degradation of one or more factors that repress cytokinin signaling. Plays an important role for balancing cell expansion with cell proliferation rates during shoot development. (267 aa)
CDT1ACDT1-like protein a, chloroplastic; Member of the pre-replication complex. Component of the plastid division machinery. Promotes polyloidization and regulates endoreduplication. Involved in the coordination of cell and plastid division. (571 aa)
RPA1AReplication protein A 70 kDa DNA-binding subunit A; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Plays an essential role at later stages of meiotic recombination events required for the formation of class I crossovers. Is essential for normal progression through meiosis in pollen mother cells. Is involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses, but does not seem to be required for the repair of meiot [...] (640 aa)
RPT2B26S proteasome regulatory subunit 4 homolog B; The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (443 aa)
RPT1B26S proteasome regulatory subunit 7 homolog B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (464 aa)
RPT1A26S proteasome regulatory subunit 7 homolog A; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (426 aa)
APC8Anaphase-promoting complex subunit 8; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of endor [...] (579 aa)
ORC1BOrigin of replication complex subunit 1B; Essential protein required for ovules fertilization. Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication (By similarity). H3K4me3 effector that regulates positively the transcription of a subset of genes. Belongs to the ORC1 family. (813 aa)
RPT2A26S proteasome regulatory subunit 4 homolog A; The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. Is required for the maintenance of postembryonic root and shoot meristems. Has a specific role in the regulation of organs size. (443 aa)
PBC1Proteasome subunit beta type-3-A; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1B family. (204 aa)
NTL8NAC domain-containing protein 40; Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP), probably via metalloprotease activity. Regulates gibberellic acid-mediated salt- responsive repression of seed germination and flowering via FT, thus delaying seed germination under high salinity conditions. (335 aa)
NF-YB11Putative CCAAT-binding transcription factor subunit. (275 aa)
ORC6Origin of replication complex subunit 6; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication; Belongs to the ORC6 family. (284 aa)
PCNA2Proliferating cell nuclear antigen 2; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand (By similarity). May be involved in UV resistance. Belongs to the PCNA family. (264 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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