STRINGSTRING
A0A1I9LQI3 A0A1I9LQI3 A0A1I9LT28 A0A1I9LT28 A0A1P8ARQ6 A0A1P8ARQ6 A0A1P8B3C0 A0A1P8B3C0 Dl3755W Dl3755W A0A1P8BD70 A0A1P8BD70 REV1 REV1 UFD1 UFD1 NAC014 NAC014 F25A4.26 F25A4.26 POL2A POL2A F14L17.24 F14L17.24 F4HWA5_ARATH F4HWA5_ARATH F4HXC5_ARATH F4HXC5_ARATH F28J9.5 F28J9.5 T1G11.9 T1G11.9 F14D16.3 F14D16.3 POL2B POL2B MEE13 MEE13 F4IHC4_ARATH F4IHC4_ARATH F4IZL5_ARATH F4IZL5_ARATH F4JA83_ARATH F4JA83_ARATH T27D20.13 T27D20.13 NTL9 NTL9 F28A21.230 F28A21.230 F22K18.10 F22K18.10 RPA1E RPA1E T14C9.100 T14C9.100 MRA19.13 MRA19.13 DDB1B DDB1B STI STI ANAC023 ANAC023 T13D8.18 T13D8.18 T13D8.21 T13D8.21 NAC024 NAC024 T13D8.25 T13D8.25 CDC48A CDC48A RPS27AB RPS27AB RPS27AC RPS27AC RPS27AA RPS27AA Q058G7_ARATH Q058G7_ARATH POLD4 POLD4 T4C15.5 T4C15.5 DPB2 DPB2 POLK POLK T9I4.15 T9I4.15 REV3 REV3 NAC074 NAC074 POLH POLH CUL4 CUL4 BTS BTS RFC3 RFC3 MIEL1 MIEL1 LRS1 LRS1 RFC4 RFC4 Q94C55_ARATH Q94C55_ARATH NAC089 NAC089 REV7 REV7 RFC1 RFC1 Q9C5C7_ARATH Q9C5C7_ARATH T22A15.5 T22A15.5 F14G24.22 F14G24.22 RFC2 RFC2 T5M16.21 T5M16.21 RFC5 RFC5 RZPF34 RZPF34 RPA1C RPA1C RPA1D RPA1D UBP24 UBP24 T14P4.13 T14P4.13 F12A21.25 F12A21.25 Q9LH38_ARATH Q9LH38_ARATH CDC48E CDC48E DDB1A DDB1A PCNA PCNA NAC049 NAC049 NAC062 NAC062 CDC48D CDC48D RPA1B RPA1B RPA1A RPA1A T6H20.60 T6H20.60 F19H22.30 F19H22.30 F16J13.170 F16J13.170 NTL8 NTL8 CDC48B CDC48B NF-YB11 NF-YB11 PCNA2 PCNA2
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
A0A1I9LQI3Replication protein A1. (177 aa)
A0A1I9LT28Uncharacterized protein. (248 aa)
A0A1P8ARQ6Uncharacterized protein. (1041 aa)
A0A1P8B3C0Replication-like protein. (139 aa)
Dl3755WUbiquitin fusion degradation UFD1 family protein. (684 aa)
A0A1P8BD70Nucleic acid-binding, OB-fold-like protein. (192 aa)
REV1DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair and translesion synthesis (TLS). Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. Mediates also the insertion of dTMP or dGMP when the opposite base is G, and, with a low efficiency, dGMP insertions opposite G, T, and C, dAMP insertions opposite G, A, and T, and dTMP insertion opposite A. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemi [...] (1105 aa)
UFD1Ubiquitin fusion degradation 1. (340 aa)
NAC014NAC domain-containing protein 14; Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). (652 aa)
F25A4.26Zinc finger protein BRUTUS-like At1g74770; Probable E3 ubiquitin-protein ligase that may regulate the response to iron deficiency and thus contributes to iron homeostasis. (1259 aa)
POL2ADNA polymerase epsilon catalytic subunit A; DNA polymerase II, which participates in chromosomal DNA replication. Required for the timing and determination of cell fate during plant embryogenesis and root pole development, by promoting cell cycle and cell type patterning. Necessary for proper shoot (SAM) and root apical meristem (RAM) functions. Involved in maintaining epigenetic states, controlling hypersensitive response (HR), and mediating abscisic acid (ABA) signaling. Required for flowering repression through a mechanism involving epigenetic gene silencing. May participate in proc [...] (2161 aa)
F14L17.24Protein STICHEL-like 1. (1116 aa)
F4HWA5_ARATHE3 ubiquitin ligase. (170 aa)
F4HXC5_ARATHF-box protein. (243 aa)
F28J9.5Nucleic acid-binding proteins superfamily. (351 aa)
T1G11.9Holliday junction resolvase. (997 aa)
F14D16.3Zinc finger protein BRUTUS-like At1g18910; Probable E3 ubiquitin-protein ligase that may regulate the response to iron deficiency and thus contributes to iron homeostasis. (1254 aa)
POL2BDNA polymerase epsilon catalytic subunit B; DNA polymerase II, which participates in chromosomal DNA replication (By similarity). Involved in the determination of cell fate during plant embryogenesis. Contributes to the flowering time repression. (2138 aa)
MEE13Myosin heavy chain-like protein. (652 aa)
F4IHC4_ARATHNucleic acid-binding, OB-fold-like protein. (532 aa)
F4IZL5_ARATHZinc finger (C3HC4-type RING finger) family protein. (287 aa)
F4JA83_ARATHNucleic acid-binding proteins superfamily. (309 aa)
T27D20.13P-loop containing nucleoside triphosphate hydrolases superfamily protein; Belongs to the AAA ATPase family. (600 aa)
NTL9Protein NTM1-like 9; Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). Calmodulin-regulated transcriptional repressor. Binds several synthetic promoters with randomly selected binding sites. Functions synergistically with SNI1 as negative regulator of pathogen-induced PR1 expression and basal resistance to a virulent strain of P.syringae. Binds directly to the promoter of the PR1 gene. Acts as positive regulator of innate immunity. Involved in the effector-triggered immunity (ETI) induction of immunity-related gene expression [...] (512 aa)
F28A21.230Protein STICHEL-like 3; Belongs to the DnaX/STICHEL family. (1097 aa)
F22K18.10Protein STICHEL-like 2; Belongs to the DnaX/STICHEL family. (857 aa)
RPA1EReplication protein A 70 kDa DNA-binding subunit E; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (By similarity). (784 aa)
T14C9.100CHY-type/CTCHY-type/RING-type Zinc finger protein. (318 aa)
MRA19.13Protein STICHEL-like 4. (966 aa)
DDB1BDNA damage-binding protein 1b; Component of light signal transduction machinery. Involved in repression of photomorphogenesis in darkness (By similarity). Plays a role in DNA repair by forming with DDB2 the UV-damaged DNA-binding protein complex (UV-DDB) (By similarity); Belongs to the DDB1 family. (1088 aa)
STIProtein STICHEL; Acts as a key regulator of trichome branching through an endoreduplication-independent pathway. (1218 aa)
ANAC023NAC domain containing protein 23. (347 aa)
T13D8.18NAC (No Apical Meristem) domain transcriptional regulator superfamily protein. (322 aa)
T13D8.21NAC (No Apical Meristem) domain transcriptional regulator superfamily protein. (371 aa)
NAC024NAC domain containing protein 24. (320 aa)
T13D8.25NAC (No Apical Meristem) domain transcriptional regulator superfamily protein. (318 aa)
CDC48ACell division control protein 48 homolog A; Probably functions in cell division and growth processes. Interacts with certain SNAREs as part of specialized membrane fusion events where vesicles from the same organelle fuse (homotypic fusion) (By similarity). (809 aa)
RPS27ABUbiquitin-40S ribosomal protein S27a-2; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-11-linked is invol [...] (157 aa)
RPS27ACUbiquitin-40S ribosomal protein S27a-3; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-11-linked is invol [...] (157 aa)
RPS27AAUbiquitin-40S ribosomal protein S27a-1; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-11-linked is invol [...] (156 aa)
Q058G7_ARATHF-box family protein. (114 aa)
POLD4Polymerase delta 4. (124 aa)
T4C15.5F-box protein At2g35280. (163 aa)
DPB2DNA polymerase epsilon subunit B; As accessory component of DNA polymerase II participates in chromosomal DNA replication. Required for the timing and determination of cell fate during plant embryogenesis and root pole development, by promoting cell cycle and cell type patterning. Necessary for proper shoot (SAM) and root apical meristem (RAM) functions (By similarity). Is essential to promote the first divisions of the zygote. (526 aa)
POLKDNA polymerase kappa; Template-directed low-fidelity DNA polymerase specifically involved in DNA repair. Able to extend primer-terminal mispairs, and to insert nucleotides opposite to a single 7,8-dihydro-8-oxoGuanine (8-oxoG) lesion and moderately extend from the resulting primer end, thus leading to both error-free and error-prone bypass of 8-oxoG DNA lesions. Probably involved in consecutive DNA replication cycles in the absence of mitosis. Binds preferentially template-primer DNA substrates or single-stranded DNA. Plays an important role in translesion synthesis, where the normal h [...] (671 aa)
T9I4.15Ubiquitin fusion degradation UFD1 family protein. (312 aa)
REV3DNA polymerase zeta catalytic subunit; Catalytic subunit of the error prone DNA polymerase zeta. Involved in damage-tolerance mechanisms through translesion DNA synthesis. (1890 aa)
NAC074NAC domain containing protein 74. (352 aa)
POLHDNA polymerase eta; Error-free DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis (TLS), where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers and confers resistance to ultraviolet light. Depending on the context, it inserts the correct base, but may cause base transitions and transversions. Forms a Schiff base with 5'- deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci. Exhibits [...] (672 aa)
CUL4Cullin-4; Component of the CUL4-RBX1-CDD (COP10-DDB1a-DET1) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Participates in the CDD complex to light-mediated control of development. May repress photomorphogenesis through enhancing COP1 E3 ubiquitin-protein ligase activity. Acts together with the CUL4-DDB1-COP1-SPA E3 ubiquitin- protein ligase complexes in the repression of photomorphogenesis and flowering time. Component ot the CUL4-RBX1-DDB1-PRL1 E3 ubiquitin- protein ligase complex which mediates ubiquit [...] (792 aa)
BTSZinc finger protein BRUTUS; Essential protein. Negatively regulates the response to iron deficiency and thus contributes to iron homeostasis. Exhibits E3 ubiquitin-protein ligase activity in vitro. Plays a role in root growth, rhizosphere acidification, and iron reductase activity in response to iron deprivation. Facilitates 26S proteasome-mediated degradation of PYEL proteins in the absence of iron. (1254 aa)
RFC3Replication factor C subunit 3; May be involved in DNA replication and thus regulate cell proliferation. (354 aa)
MIEL1E3 ubiquitin-protein ligase MIEL1; E3 ubiquitin-protein ligase that acts as a regulator of cell death and defense. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Attenuates the activation of defense and related cell death responses in the absence of pathogens by mediating ubiquitination and subsequent proteasomal degradation of MYB30. (267 aa)
LRS1Transducin/WD40 repeat-like superfamily protein. (753 aa)
RFC4Replication factor C subunit 4; May be involved in DNA replication and thus regulate cell proliferation; Belongs to the activator 1 small subunits family. (339 aa)
Q94C55_ARATHTransducin/WD40 repeat-like superfamily protein. (535 aa)
NAC089NAC domain-containing protein 89; Transcription factor involved in plant cell division. (340 aa)
REV7DNA polymerase zeta processivity subunit; Regulatory subunit of the error prone DNA polymerase zeta. Involved in damage-tolerance mechanisms through translesion DNA synthesis (By similarity). (215 aa)
RFC1Replication factor C subunit 1; Plays a role as mediator of transcriptional gene silencing (TGS), DNA replication, DNA repair, hypersensitive response (HR) and telomere length regulation. Is required in meiosis for DNA double- strand break (DSB) repair during meiotic homologous recombination. May participate in the RAD51-mediated recombination intermediate repair process. Is important for lagging strand synthesis. Promotes meiotic recombination via a specific pathway for crossovers (COs) that involves the formation of double Holliday Junction (dHJ) intermediates. (956 aa)
Q9C5C7_ARATHAAA-type ATPase family protein / ankyrin repeat family protein. (481 aa)
T22A15.5F-box family protein. (80 aa)
F14G24.22Nucleic acid-binding, OB-fold-like protein. (566 aa)
RFC2Replication factor C subunit 2; May be involved in DNA replication and thus regulate cell proliferation. (333 aa)
T5M16.21P-loop containing nucleoside triphosphate hydrolases superfamily protein. (1151 aa)
RFC5Replication factor C subunit 5; Functions in cell replication and proliferation. May be involved in chromatin assembly and remodeling. Plays a role in the negative control of pathogenesis-related gene expression and systemic acquired resistance (SAR). (369 aa)
RZPF34E3 ubiquitin-protein ligase RZFP34; Possesses E3 ubiquitin-protein ligase activity in vitro. Mediates mainly 'Lys-48'-linked polyubiquitination. Promotes abscisic acid (ABA)-induced stomatal closure, reactive oxygen species (ROS) production and drought tolerance. Involved in the regulation of stomatal aperture. (291 aa)
RPA1CReplication protein A 70 kDa DNA-binding subunit C; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (By similarity). (853 aa)
RPA1DReplication protein A 70 kDa DNA-binding subunit D; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (By similarity). (629 aa)
UBP24Ubiquitin carboxyl-terminal hydrolase 24; Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity). Belongs to the peptidase C19 family. (551 aa)
T14P4.13T14P4.13 protein. (290 aa)
F12A21.25Putative F-box protein At1g67623. (296 aa)
Q9LH38_ARATHUncharacterized protein. (161 aa)
CDC48ECell division control protein 48 homolog E; Probably functions in cell division and growth processes. Interacts with certain SNAREs as part of specialized membrane fusion events where vesicles from the same organelle fuse (homotypic fusion) (By similarity); Belongs to the AAA ATPase family. (810 aa)
DDB1ADNA damage-binding protein 1a; Component of light signal transduction machinery. Involved in repression of photomorphogenesis in darkness by participating in the CDD complex, a complex probably required to regulate the activity of ubiquitin conjugating enzymes (E2s). Repression of photomorphogenesis is probably mediated by ubiquitination and subsequent degradation of photomorphogenesis-promoting factors such as HY5, HYH and LAF1. Plays a role in DNA repair by forming with DDB2 the UV-damaged DNA-binding protein complex (UV-DDB). Component of the CUL4-RBX1-DDB1-PRL1 E3 ubiquitin-protein [...] (1088 aa)
PCNAProliferating cellular nuclear antigen 1; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (263 aa)
NAC049NAC domain containing protein 49. (198 aa)
NAC062NAC domain-containing protein 62; Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). Transcriptional activator involved in response to cold stress. Mediates induction of pathogenesis-related (PR) genes independently of salicylic signaling in response to cold. Binds directly to the PR gene promoters and enhances plant resistance to pathogen infection, incorporating cold signals into pathogen resistance responses. Plays a regulatory role in abscisic acid (ABA)-mediated drought-resistance response. (469 aa)
CDC48DCell division control protein 48 homolog D; Probably functions in cell division and growth processes. Interacts with certain SNAREs as part of specialized membrane fusion events where vesicles from the same organelle fuse (homotypic fusion) (By similarity); Belongs to the AAA ATPase family. (815 aa)
RPA1BReplication protein A 70 kDa DNA-binding subunit B; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions (By similarity). Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (By similarity). (604 aa)
RPA1AReplication protein A 70 kDa DNA-binding subunit A; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Plays an essential role at later stages of meiotic recombination events required for the formation of class I crossovers. Is essential for normal progression through meiosis in pollen mother cells. Is involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses, but does not seem to be required for the repair of meiot [...] (640 aa)
T6H20.60Putative cullin-like protein 4; Belongs to the cullin family. (247 aa)
F19H22.30Putative ubiquitin-dependent proteolytic protein. (315 aa)
F16J13.170Cullin-like protein 5; Belongs to the cullin family. (434 aa)
NTL8NAC domain-containing protein 40; Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP), probably via metalloprotease activity. Regulates gibberellic acid-mediated salt- responsive repression of seed germination and flowering via FT, thus delaying seed germination under high salinity conditions. (335 aa)
CDC48BCell division control protein 48 homolog B; Probably functions in cell division and growth processes. Interacts with certain SNAREs as part of specialized membrane fusion events where vesicles from the same organelle fuse (homotypic fusion) (By similarity); Belongs to the AAA ATPase family. (603 aa)
NF-YB11Putative CCAAT-binding transcription factor subunit. (275 aa)
PCNA2Proliferating cell nuclear antigen 2; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand (By similarity). May be involved in UV resistance. Belongs to the PCNA family. (264 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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