STRINGSTRING
HCC2 HCC2 XTH10 XTH10 XTH21 XTH21 F5O8.36 F5O8.36 SNL6 SNL6 SNL5 SNL5 CYTC-2 CYTC-2 COX6A COX6A L73G19.60 L73G19.60 L73G19.40 L73G19.40 WRKY19 WRKY19 F14N23.13 F14N23.13 COX6B-3 COX6B-3 F6D8.4 F6D8.4 COX5B-2 COX5B-2 SNL1 SNL1 F11C1_20 F11C1_20 F11C1_40 F11C1_40 F3A4.200 F3A4.200 F3A4.210 F3A4.210 F3A4.230 F3A4.230 F1O11.6 F1O11.6 T1B9.26 T1B9.26 SURF1 SURF1 F23A5.4 F23A5.4 F11C1_10 F11C1_10 COX6B-1 COX6B-1 COX5B-1 COX5B-1 MQL5.17 MQL5.17 HO4 HO4 F6N18.10 F6N18.10 T1N15.12 T1N15.12 Q9LK19_ARATH Q9LK19_ARATH SNL2 SNL2 F2G14.160 F2G14.160 F2I11.180 F2I11.180 LTPG3 LTPG3 F17L21.5 F17L21.5 HOS15 HOS15 MJE4.6 MJE4.6 T4M5.4 T4M5.4 HO3 HO3 COX6B-2 COX6B-2 SPPL1 SPPL1 dl4780c dl4780c HCC1 HCC1 T2E6.19 T2E6.19 F3I6.14 F3I6.14 COX11 COX11 PRMT13 PRMT13 F20P5.23 F20P5.23 F21J6.101 F21J6.101 Q45GK4_ARATH Q45GK4_ARATH T9L24.28 T9L24.28 COX2 COX2 COX3 COX3 COX1 COX1 F17H15.14 F17H15.14 F13D4.5 F13D4.5 SPP SPP F10N7.210 F10N7.210 HO1 HO1 HO2 HO2 F3I6.18 F3I6.18 F3I6.15 F3I6.15 SNL3 SNL3 CYTC-1 CYTC-1 F17L21.4 F17L21.4 F17L21.3 F17L21.3 SNL4 SNL4 F2G14.150 F2G14.150 F4J0F5_ARATH F4J0F5_ARATH F4IZC0_ARATH F4IZC0_ARATH F4IZB4_ARATH F4IZB4_ARATH F3I6.13 F3I6.13 F26G16.17 F26G16.17 F4HRC0_ARATH F4HRC0_ARATH F17L21.6 F17L21.6 F17L21.32 F17L21.32 F17L21.2 F17L21.2 F3I6.16 F3I6.16 PRMT14 PRMT14 cox3 cox3 cox2 cox2 A0A1P8BFD5 A0A1P8BFD5 A0A1P8ASE3 A0A1P8ASE3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCC2Protein SCO1 homolog 2, mitochondrial; Thought to play a role in cellular copper homeostasis, mitochondrial redox signaling or insertion of copper into the active site of COX (By similarity). Participates in copper and redox homeostasis; Belongs to the SCO1/2 family. (276 aa)
XTH10Probable xyloglucan endotransglucosylase/hydrolase protein 10; Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues (By similarity); Belongs to the glycosyl hydrolase 16 family. XTH group 1 subfamily. (299 aa)
XTH21Probable xyloglucan endotransglucosylase/hydrolase protein 21; Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues (By similarity); Belongs to the glycosyl hydrolase 16 family. XTH group 2 subfamily. (305 aa)
F5O8.36Paired amphipathic helix (PAH2) superfamily protein. (241 aa)
SNL6Paired amphipathic helix protein Sin3-like 6; Acts as a transcriptional repressor. Plays roles in regulating gene expression and genome stability (By similarity). (1173 aa)
SNL5Paired amphipathic helix protein Sin3-like 5; Acts as a transcriptional repressor. Plays roles in regulating gene expression and genome stability (By similarity). (1162 aa)
CYTC-2Cytochrome c-2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (112 aa)
COX6ACytochrome c oxidase subunit 6a, mitochondrial; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (102 aa)
L73G19.60PPPDE putative thiol peptidase family protein. (252 aa)
L73G19.40PPPDE putative thiol peptidase family protein. (255 aa)
WRKY19Probable WRKY transcription factor 19; Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element. May act also as a disease resistance protein with a serine/threonine-protein kinase activity (By similarity). (1895 aa)
F14N23.13Paired amphipathic helix Sin3-like protein. (77 aa)
COX6B-3Cytochrome c oxidase subunit 6b-3; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. This protein may be one of the heme-binding subunits of the oxidase. (78 aa)
F6D8.4Putative cytochrome c oxidase subunit 5b-like. (90 aa)
COX5B-2Cytochrome c oxidase subunit 5b-2, mitochondrial; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport; Belongs to the cytochrome c oxidase subunit 5B (TC 3.D.4.11) family. (171 aa)
SNL1Paired amphipathic helix protein Sin3-like 1; Acts as a transcriptional repressor. An histone deacetylase (HDAC) activity is required for transcription repression. May play a role in telomere stability. (1372 aa)
F11C1_20Transmembrane protein, putative (DUF247). (588 aa)
F11C1_40Uncharacterized protein F11C1_40. (231 aa)
F3A4.200Transmembrane protein, putative (DUF247). (531 aa)
F3A4.210Transmembrane protein, putative (DUF247). (564 aa)
F3A4.230Transmembrane protein, putative (DUF247). (509 aa)
F1O11.6Transmembrane protein, putative (DUF247). (448 aa)
T1B9.26PPPDE putative thiol peptidase family protein. (265 aa)
SURF1Surfeit locus protein 1; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 (TC 3.D.4.8) family. (354 aa)
F23A5.4PPPDE putative thiol peptidase family protein. (231 aa)
F11C1_10Transmembrane protein, putative (DUF247). (541 aa)
COX6B-1Cytochrome c oxidase subunit 6b-1; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. This protein may be one of the heme-binding subunits of the oxidase. (191 aa)
COX5B-1Cytochrome c oxidase subunit 5b-1, mitochondrial; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (176 aa)
MQL5.17PPPDE putative thiol peptidase family protein. (245 aa)
HO4Heme oxygenase 4, chloroplastic; Catalyzes the opening of the heme ring to form the open-chain tetrapyrrole biliverdin IX with the release of iron and carbon monoxide (CO). Produces specifically the biliverdin IX-alpha isomer. Plays a minor role in phytochrome assembly and photomorphogenesis. (283 aa)
F6N18.10Putative cytochrome c oxidase subunit 6b-like; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. This protein may be one of the heme-binding subunits of the oxidase (By similarity). (134 aa)
T1N15.12Surfeit locus protein 1-like; May be involved in the biogenesis of the COX complex. (384 aa)
Q9LK19_ARATHPaired amphipathic helix Sin3-like protein. (374 aa)
SNL2Paired amphipathic helix protein Sin3-like 2; Acts as a transcriptional repressor. Plays roles in regulating gene expression and genome stability (By similarity). (1367 aa)
F2G14.160Paired amphipathic helix (PAH2) superfamily protein. (87 aa)
F2I11.180Transmembrane protein, putative (DUF247). (422 aa)
LTPG3Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein. (180 aa)
F17L21.5Paired amphipathic helix (PAH2) superfamily protein. (241 aa)
HOS15WD40 repeat-containing protein HOS15; Acts as repressor of cold stress-regulated gene expression. Interacts specifically with and promotes deacetylation of histone H4. Plays a role in gene regulation for plant acclimation and tolerance to cold stress. (613 aa)
MJE4.6Paired amphipathic helix (PAH2) superfamily protein. (155 aa)
T4M5.4Dentin sialophosphoprotein-like protein. (828 aa)
HO3Heme oxygenase 3, chloroplastic; Catalyzes the opening of the heme ring to form the open-chain tetrapyrrole biliverdin IX with the release of iron and carbon monoxide (CO). Produces specifically the biliverdin IX-alpha isomer. Plays a minor role in phytochrome assembly and photomorphogenesis. (285 aa)
COX6B-2Cytochrome c oxidase subunit 6b-2; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. This protein may be one of the heme-binding subunits of the oxidase. (78 aa)
SPPL1Signal peptide peptidase-like 1; Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. (372 aa)
dl4780cDeSI-like protein At4g17486. (224 aa)
HCC1Protein SCO1 homolog 1, mitochondrial; Thought to play a role in cellular copper homeostasis, mitochondrial redox signaling or insertion of copper into the active site of COX. Plays an essential role in embryo development. Belongs to the SCO1/2 family. (334 aa)
T2E6.19PPPDE putative thiol peptidase family protein. (279 aa)
F3I6.14Paired amphipathic helix (PAH2) superfamily protein. (155 aa)
COX11Cytochrome c oxidase assembly protein COX11, mitochondrial; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG (TC 3.D.4.8) family. (287 aa)
PRMT13Probable histone-arginine methyltransferase 1.3; Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, and mRNA stability (By similarity). Recruited to promoters upon gene activation, methylates histone H3 and activates transcription via chromatin remodeling. Positive regulator in the oxidative stress tolerance that promotes the expression of enzymes preventing oxidative stress such as APX1 and GPX1 by histone methylation (H3R17me2a). Confers tolerance to cadmium CdCl(2) and s [...] (535 aa)
F20P5.23Paired amphipathic helix (PAH2) superfamily protein. (160 aa)
F21J6.101PPPDE putative thiol peptidase family protein. (218 aa)
Q45GK4_ARATHTransmembrane protein, putative (DUF247). (503 aa)
T9L24.28Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein. (147 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (260 aa)
COX3Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (265 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (527 aa)
F17H15.14Probable transcriptional regulatory protein At2g25830; Belongs to the TACO1 family. (331 aa)
F13D4.5PPPDE putative thiol peptidase family protein. (240 aa)
SPPSignal peptide peptidase; Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane (By similarity). Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm (By similarity). Plays a critical role in the development and function of the reproductive tissues, especially in pollen development. Belongs to the peptidase A22B family. (344 aa)
F10N7.210PPPDE thiol peptidase family protein. (680 aa)
HO1Heme oxygenase 1, chloroplastic; Key enzyme in the synthesis of the chromophore of the phytochrome family of plant photoreceptors. Catalyzes the opening of the heme ring to form the open-chain tetrapyrrole biliverdin IX with the release of iron and carbon monoxide (CO). Produces specifically the biliverdin IX-alpha isomer. Can form complex with heme, is ferredoxin- dependent and its activity is increased in the presence of ascorbate. Plays a role in salt acclimation signaling. May affect the plastid-to- nucleus signaling pathway by perturbing tetrapyrrole synthesis. The plastid-to-nucl [...] (282 aa)
HO2Probable inactive heme oxygenase 2, chloroplastic; Probable inactive heme oxygenase. Binds protoporphyrin IX, a precursor for both heme and chlorophyll biosynthesis. Plays a minor role in phytochrome assembly and photomorphogenesis. (299 aa)
F3I6.18Paired amphipathic helix (PAH2) superfamily protein. (252 aa)
F3I6.15Paired amphipathic helix repeat-containing protein. (744 aa)
SNL3Paired amphipathic helix protein Sin3-like 3; Acts as a transcriptional repressor. Interacts with ERF7 to repress genes in abscisic acid and drought stress responses. The heterodimer represses transcription by tethering SNL3 to DNA. (1330 aa)
CYTC-1Cytochrome c-1; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (114 aa)
F17L21.4Paired amphipathic helix (PAH2) superfamily protein. (137 aa)
F17L21.3Paired amphipathic helix (PAH2) superfamily protein. (186 aa)
SNL4Paired amphipathic helix protein Sin3-like 4; Acts as a transcriptional repressor. Plays roles in regulating gene expression and genome stability (By similarity). (1326 aa)
F2G14.150Paired amphipathic helix Sin3-like protein. (139 aa)
F4J0F5_ARATHPaired amphipathic helix SIN3-like protein. (355 aa)
F4IZC0_ARATHTransmembrane protein, putative (DUF247). (493 aa)
F4IZB4_ARATHTransmembrane protein, putative (DUF247). (539 aa)
F3I6.13Paired amphipathic helix (PAH2) superfamily protein. (196 aa)
F26G16.17S-adenosyl-L-methionine-dependent methyltransferase superfamily protein. (239 aa)
F4HRC0_ARATHS-adenosyl-L-methionine-dependent methyltransferases superfamily protein. (538 aa)
F17L21.6Paired amphipathic helix (PAH2) superfamily protein. (225 aa)
F17L21.32Paired amphipathic helix (PAH2) superfamily protein. (222 aa)
F17L21.2Paired amphipathic helix repeat-containing protein. (184 aa)
F3I6.16Paired amphipathic helix (PAH2) superfamily protein. (245 aa)
PRMT14Probable histone-arginine methyltransferase 1.4; Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, and mRNA stability. Recruited to promoters upon gene activation, methylates histone H3 and activates transcription via chromatin remodeling; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (528 aa)
cox3Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (265 aa)
cox2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (260 aa)
A0A1P8BFD5Paired amphipathic helix Sin3-like protein. (122 aa)
A0A1P8ASE3S-adenosyl-L-methionine-dependent methyltransferase superfamily protein. (233 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.