STRINGSTRING
AMC5 AMC5 AMC4 AMC4 AMC8 AMC8 AMC9 AMC9 AMC3 AMC3 AMC1 AMC1 AMC2 AMC2 AMC7 AMC7 bVPE bVPE ALPHA-VPE ALPHA-VPE AMC6 AMC6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMC5Metacaspase-5; Cysteine protease that cleaves specifically after arginine or lysine residues. Does not cleave caspase-specific substrates. May be involved in the modulation of programmed cell death activated by oxidative stress. (410 aa)
AMC4Metacaspase-4 subunit p10; Cysteine protease that cleaves specifically after arginine or lysine residues. Does not cleave caspase-specific substrates. Plays a positive regulatory role in biotic and abiotic stress-induced programmed cell death. (418 aa)
AMC8Metacaspase-8; Cysteine protease that cleaves specifically after arginine residues. Does not cleave caspase-specific substrates. May be involved in the modulation of programmed cell death activated by oxidative stress; Belongs to the peptidase C14B family. (381 aa)
AMC9Metacaspase-9 subunit p10; Cysteine protease that cleaves specifically after arginine or lysine residues. Does not cleave caspase-specific substrates. Required for proteolytic processing of GRI. Belongs to the peptidase C14B family. (325 aa)
AMC3Metacaspase-3. (362 aa)
AMC1Metacaspase-1; Cysteine protease that cleaves specifically after arginine or lysine residues. Does not cleave caspase-specific substrates. Acts as a positive regulator of cell death. Required for both oxidative stress cell death response and hypersensitive cell death response mediated by immune response. (367 aa)
AMC2Metacaspase-2; Acts as a negative regulator of oxidative stress cell death and hypersensitive cell death response mediated by immune response. Acts via indirect or direct regulation of AMC1 at postranscriptional level; Belongs to the peptidase C14B family. (418 aa)
AMC7Metacaspase-7; Belongs to the peptidase C14B family. (403 aa)
bVPEVacuolar-processing enzyme beta-isozyme; Asparagine-specific endopeptidase involved in the processing of vacuolar seed protein precursors into the mature forms (By similarity). Probably involved in post-translational proteolysis of seed storage proteins in the protein storage vacuole of developing seeds. (486 aa)
ALPHA-VPEVacuolar-processing enzyme alpha-isozyme; Asparagine-specific endopeptidase involved in the processing of vacuolar seed protein precursors into the mature forms. Probably involved in post-translational proteolysis of seed storage proteins in the protein storage vacuole of developing seeds. (478 aa)
AMC6Metacaspase-6; Belongs to the peptidase C14B family. (368 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: medium (56%) [HD]