STRINGSTRING
AUG1 AUG1 T1N15.4 T1N15.4 F6N18.16 F6N18.16 AUG2 AUG2 GCR1 GCR1 TKL-2 TKL-2 TPS1 TPS1 MOD1 MOD1 TIM TIM PAP15 PAP15 CYFBP CYFBP ABCF4 ABCF4 ADR1 ADR1 DYAD DYAD BZIP8 BZIP8 AMY3 AMY3 AMY1 AMY1 F13O11.3 F13O11.3 TKL-1 TKL-1 AMY2 AMY2 T4C12_30 T4C12_30 SFGH SFGH MUK11.16 MUK11.16 Q494P3_ARATH Q494P3_ARATH SUC2 SUC2 T25N20.10 T25N20.10 CTIMC CTIMC CYCB1-1 CYCB1-1 CFBP1 CFBP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AUG1AUGMIN subunit 1; Involved in microtubules reorganization during spindle and phragmoplast development. (299 aa)
T1N15.4Dihydroxyacetone kinase. (593 aa)
F6N18.16Alcohol dehydrogenase-like 3. (394 aa)
AUG2AUGMIN subunit 2; Contributes to the assembly of the acentrosomal spindle and phragmoplast microtubule arrays as part of the augmin complex. (296 aa)
GCR1G-protein coupled receptor 1; Together with GPA1, may regulate the cell cycle via a signaling cascade that uses phosphatidylinositol-specific phospholipase C (PI-PLC) as an effector and inositol 1,4,5-trisphosphate(IP(3)) as a second messenger. Acts as a negative regulator of GPA1-mediated abscisic acid (ABA) responses in guard cells, and together with GPA1 and GB1 during seed germination and early seedling development. Promotes PI-PLC activity and IP(3) accumulation. Involved in the blue light (BL) signaling. Together with GPA1 and ADT3, required for BL- mediated synthesis of phenylpy [...] (326 aa)
TKL-2Transketolase-2, chloroplastic; Catalyzes the reversible transfer of a two-carbon ketol group from fructose-6-phosphate or sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate to yield xylulose-5-phosphate and erythrose- 4-phosphate or ribose-5-phosphate, respectively (By similarity). Could act as a stress sensor involved in adaptation process; Belongs to the transketolase family. (741 aa)
TPS1Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1; Required for normal embryo development, vegetative growth and transition to flowering. Regulates embryo growth, cell wall deposition, starch and sucrose degradation, but not cell differentiation. Involved in the regulation of glucose sensing and signaling genes during plant development. (942 aa)
MOD1Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic; Catalyzes the NAD-dependent reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Catalyzes the last reduction step in the de novo synthesis cycle of fatty acids. Involved in the elongation cycle of fatty acids which are used in lipid metabolism. Required for normal plant growth. (390 aa)
TIMTriosephosphate isomerase, chloroplastic; Belongs to the triosephosphate isomerase family. (315 aa)
PAP15Purple acid phosphatase 15; Acid phosphatase activity with p-nitrophenyl phosphate (pNPP), D-myoinositol 1-phosphate (Ins(1)P1), phytic acid and Myo- inositol hexakisphosphate. Low or no activity with Glc-6-P and ATP. Confers shoot growth stimulation, enhanced salt and osmotic stress tolerance, and ABA insensitivity. May modulate ascorbic acid (AsA) levels by controlling the input of myoinositol into this branch of AsA biosynthesis. (532 aa)
CYFBPFructose-1,6-bisphosphatase, cytosolic; Catalyzes the first irreversible reaction from fructose-1,6- bisphosphate to fructose-6-phosphate and inorganic phosphate and plays an important regulatory role in sucrose biosynthesis and metabolism (Probable). Its activity is essential to regulate starch levels. Functions in fructose-mediated signaling independently of its catalytic activity in sugar metabolism. May act downstream of ABA2/GIN1, which is involved in abscisic acid (ABA) synthesis to regulate autotrophic transition and modulate early seedling establishment after seed germination. [...] (341 aa)
ABCF4ABC transporter F family member 4; Belongs to the ABC transporter superfamily. ABCF family. EF3 (TC 3.A.1.121) subfamily. (723 aa)
ADR1Disease resistance protein ADR1; Disease resistance (R) protein that mediates resistance against Hyaloperonospora parasitica in a salicylic acid-dependent manner. Also mediates resistance against Erysiphe cichoracearum is both salicylic acid-dependent and partially NPR1-dependent. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. (787 aa)
DYADProtein DYAD; Required for fertility. Involved in chromatid cohesion establishment, in chromosome structure during male and female meiosis (e.g. the synapse formation between homologous chromosomes, the recombination, and the cohesion of both chromatid arm and centromere), and in axial element formation. Regulates the switch from mitosis to the reductional meiosis division of megaspores prior to the female gametogenesis (megasporogenesis). (639 aa)
BZIP8Basic leucine zipper 8; Belongs to the bZIP family. (138 aa)
AMY3Alpha-amylase 3, chloroplastic; Possesses endoamylolytic activity in vitro, but seems not required for breakdown of transitory starch in leaves. May be involved in the determination of the final structure of glucans by shortening long linear phospho-oligosaccharides in the chloroplast stroma. Can act on both soluble and insoluble glucan substrates to release small linear and branched malto-oligosaccharides. Works synergistically with beta-amylase toward efficient starch degradation. Has activity against p-nitrophenyl maltoheptaoside (BPNP-G7), amylopectin and beta-limit dextrin. Involv [...] (887 aa)
AMY1Alpha-amylase 1; Possesses alpha-amylase activity in vitro, but seems not required for breakdown of transitory starch in leaves. (423 aa)
F13O11.3Alcohol dehydrogenase-like 4; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (380 aa)
TKL-1Transketolase-1, chloroplastic; Catalyzes the reversible transfer of a two-carbon ketol group from fructose-6-phosphate or sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate to yield xylulose-5-phosphate and erythrose- 4-phosphate or ribose-5-phosphate, respectively (By similarity). Could act as a stress sensor involved in adaptation process. (741 aa)
AMY2Probable alpha-amylase 2; Probable alpha-amylase that does not seem to be required for breakdown of transitory starch in leaves. (413 aa)
T4C12_30Alcohol dehydrogenase-like 6. (381 aa)
SFGHS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (284 aa)
MUK11.16BZIP protein. (307 aa)
Q494P3_ARATHDihydroxyacetone kinase. (595 aa)
SUC2Sucrose transport protein SUC2; Responsible for the transport of sucrose into the cell, with the concomitant uptake of protons (symport system). Can also transport other glucosides such as maltose, arbutin (hydroquinone-beta-D- glucoside), salicin (2-(hydroxymethyl)phenyl-beta-D-glucoside), alpha- phenylglucoside, beta-phenylglucoside, alpha-paranitrophenylglucoside, beta-paranitrophenylglucoside, and paranitrophenyl-beta-thioglucoside. May also transport biotin. Required for apoplastic phloem sucrose loading in source tissues (e.g. leaves) in order to transport it to sink tissues (e.g [...] (512 aa)
T25N20.10Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein. (205 aa)
CTIMCTriosephosphate isomerase, cytosolic; Belongs to the triosephosphate isomerase family. (254 aa)
CYCB1-1Cyclin-B1-1. (428 aa)
CFBP1Fructose-1,6-bisphosphatase 1, chloroplastic; Catalyzes the irreversible reaction from fructose-1,6- bisphosphate to fructose-6-phosphate and inorganic phosphate, to regenerate the primary CO(2) acceptor molecule, ribulose-1,5- bisphosphate (Probable). Involved in the regulation of photosynthetic electron flow and sucrose synthesis. Its activity is critical for normal plant development and important for the regulation of a wide range of metabolic processes. (417 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.