STRINGSTRING
PHOT1 PHOT1 DRP1A DRP1A PHOT2 PHOT2 FTSZ1 FTSZ1 ARC3 ARC3 ARC5 ARC5 PMI1 PMI1 JAC1 JAC1 ARC6 ARC6 PDV1 PDV1 CHUP1 CHUP1 MIND1 MIND1 PDV2 PDV2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PHOT1Phototropin-1; Protein kinase that acts as a blue light photoreceptor in a signal-transduction pathway for photo-induced movements. Phosphorylates BLUS1, a kinase involved in stomatal opening. Required for blue light mediated mRNA destabilization. Mediates calcium spiking of extracellular origin in response to a low rate of blue light. Also mediates rapid membrane depolarization and growth inhibition in response to blue light. Necessary for root phototropism. Involved in hypocotyl phototropism under a low rate but not under a high rate of blue light. Contributes to the chloroplast accu [...] (996 aa)
DRP1ADynamin-related protein 1A; Microtubule-associated force-producing protein that is targeted to the forming cell plate during cytokinesis. Plays also a major role in plasma membrane maintenance and cell wall integrity with implications in vesicular trafficking, polar cell expansion, vascular formation, and other aspects of plant growth and development. Has a GTPase activity. (610 aa)
PHOT2Phototropin-2; Protein kinase that acts as a blue light photoreceptor in a signal-transduction pathway for photo-induced movements. Phosphorylates BLUS1, a kinase involved in stomatal opening. Mediates calcium spiking of extra- and intracellular origins in response to blue light. Involved in hypocotyl phototropism. Contributes to the chloroplast accumulation in low blue light and mediates their translocation (avoidance response) at high fluence. Regulates stomata opening and photomorphogenesis response of leaf tissue. Not involved in hypocotyl elongation inhibition, anthocyanin accumul [...] (915 aa)
FTSZ1Cell division protein FtsZ homolog 1, chloroplastic; Exhibits GTPase activity. Component of the plastid division machinery that forms a contractile ring at the division site. Required for plastid division in a dose-dependent manner. Involved in blue light-induced chloroplast movements. May regulate thylakoid development. Belongs to the FtsZ family. (433 aa)
ARC3Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 3; Z-ring accessory protein involved in the initiation of plastid division and division site placement (might functionally replace bacterial MinC). May control the rate of chloroplast expansion. Seems to influence stromule (stroma-filled tubular extensions of the plastid envelope membrane) length and frequency. (741 aa)
ARC5Dynamin-like protein ARC5; Probable GTPase component of both plastid and peroxisme division machinery. Required for the last steps of plastid division specifically in mesophyll-cell, when the narrow isthmus breaks, facilitating the separation of the daughter plastids. Necessary for peroxisome activities. Seems to influence stromule (stroma-filled tubular extensions of the plastid envelope membrane) length and frequency. Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (777 aa)
PMI1Protein PLASTID MOVEMENT IMPAIRED 1; Necessary for chloroplast and nuclear photorelocation movements via the regulation of chloroplast-actin (cp-actin) filaments in mesophyll cells, and together with PMIR1, in pavement cells. Required component for both the low- and high-light- dependent chloroplast movement responses via an abscisic acid (ABA) pathway. Involved in the ABA response pathway during seed germination. Modulates ABA accumulation during periods of water deficit at the seedling stage. (843 aa)
JAC1J domain-containing protein required for chloroplast accumulation response 1; Required for chloroplast photorelocation movement; chloroplast accumulation upon low blue light and for chloroplast movement to the bottom of cells in darkness, by modulating chloroplast actin (Cp-actin) filaments distribution, appearance and disappearance. May mediate a slight resistance to aluminum in root hair cells. (651 aa)
ARC6Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 6, chloroplastic; Component of the plastid division machinery. Involved in the initiation of proplastid and plastid division (including chloroplasts, statoliths and leukoplasts). Promotes the assembly and/or stabilization of the plastid-dividing FtsZ ring, functioning as an antagonistic regulator of FtsZ dynamics against CDP1. Relays plastid division site position between stroma and outer surface via interactions with the stromal FtsZ ring and the outer membrane PDV2 that recruits cytoplasmic ARC5 ring. Required for plastid equatoria [...] (801 aa)
PDV1Plastid division protein PDV1; Component of the plastid division machinery. Required to mediate the recruitment of ARC5 at the midplastid constriction site in the cytoplasm. (272 aa)
CHUP1Protein CHUP1, chloroplastic; Required for the positioning and movement of chloroplasts. Interacts with profilin and actin independent of its polymerization status. Regulates chloroplast localization by anchoring chloroplasts to the plasma membrane and forming a bridge to the actin cytoskeleton. (1004 aa)
MIND1Putative septum site-determining protein minD homolog, chloroplastic; Calcium-dependent ATPase required for the correct placement of the plastid division site. Inhibits FtsZ filament and ring formation in the plastid. Mediates inhibition of plastid division. In cooperation with MINE1, prevents FtsZ ring formation anywhere outside of the mid- plastids. Belongs to the ParA family. MinD subfamily. (326 aa)
PDV2Plastid division protein PDV2; Component of the plastid division machinery. Required to mediate the recruitment of ARC5 at the midplastid constriction site in the cytoplasm. Relays plastid division site position between stroma and outer surface via interactions with the cytoplasmic ARC5 and the inner membrane ARC6 that recruits stromal FtsZ ring. (307 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.