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WNK1 WNK1 LEA14 LEA14 ABI2 ABI2 PXG3 PXG3 AR781 AR781 SAUR50 SAUR50 VSP2 VSP2 DOF1.7 DOF1.7 ADH1 ADH1 FSD1 FSD1 STP1 STP1 COR47 COR47 IAA4 IAA4 ERD10 ERD10 ERD14 ERD14 GASA1 GASA1 KNAT3 KNAT3 KNAT4 KNAT4 ABI1 ABI1 IAA1 IAA1 P5CSA P5CSA CCA1 CCA1 LTI65 LTI65 ACO4 ACO4 RD29A RD29A RD22 RD22 GDH2-2 GDH2-2 XTH4 XTH4 TGA1 TGA1 ZAT12 ZAT12 ZAT5 ZAT5 MSRB6 MSRB6 XTH9 XTH9 XTH6 XTH6 RFS6 RFS6 WRKY33 WRKY33 NAC072 NAC072 SZF1 SZF1 RFS2 RFS2 ZAT10 ZAT10 SAUR62 SAUR62 BZIP8 BZIP8 F14J22.4 F14J22.4 PMI2-2 PMI2-2 MJK13.11 MJK13.11 LTP4 LTP4 LTP3 LTP3 BGLU16 BGLU16 ABF3 ABF3 ACP4 ACP4 SAUR16 SAUR16 T4E14.7 T4E14.7
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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WNK1Serine/threonine-protein kinase WNK1; Regulates flowering time by modulating the photoperiod pathway. Phosphorylates APRR3. (700 aa)
LEA14Probable desiccation-related protein LEA14; Belongs to the LEA type 2 family. (151 aa)
ABI2Protein phosphatase 2C 77; Repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, osmotic water permeability of the plasma membrane (Pos), high light stress, response to glucose, seed germination and inhibition of vegetative growth. During the stomatal closure regulation, modulates the inward calcium-channel permeability as well as H(2)O(2) and oxidative burst in response to ABA and dehydration. Represses GHR1 and, to some extent, SRK2E/OST1, kinases involved in the regulation of SLAC1-dependent stomatal closure. Controls [...] (423 aa)
PXG3Probable peroxygenase 3; Probable calcium-binding peroxygenase. May be involved in the degradation of storage lipid in oil bodies, in abiotic stress-related signaling pathway and in drought tolerance through stomatal control under water deficit conditions. (236 aa)
AR781AR781, pheromone receptor-like protein (DUF1645). (317 aa)
SAUR50Auxin-responsive protein SAUR50; Effector of hormonal and environmental signals in plant growth. (107 aa)
VSP2Vegetative storage protein 2; May function as somatic storage protein during early seedling development; Belongs to the APS1/VSP family. (265 aa)
DOF1.7Dof zinc finger protein DOF1.7; Transcription factor that binds specifically to a 5'-AA[AG]G- 3' consensus core sequence. (194 aa)
ADH1Alcohol dehydrogenase class-P; Alcohol dehydrogenase mostly active on ethanol (EtOH), but exhibits broad substrates selectivity for primary and secondary alcohols (e.g. butanol, propyl alcohol, pentanol, isopentanol, ethylene glycol, isopropanol, methanol and tertiary butyl alcohol). Converts allyl alcohol to highly toxic acryl- aldehyde. Required for survival and acclimation in hypoxic conditions, especially in roots. (379 aa)
FSD1Superoxide dismutase [Fe] 1, chloroplastic; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. (212 aa)
STP1Sugar transport protein 1; Major hexose transporter. Mediates an active uptake of hexoses, by sugar/hydrogen symport. Can transport glucose, 3-O- methylglucose, fructose, xylose, mannose, galactose, fucose, 2- deoxyglucose and arabinose. Confers sensitivity to galactose in seedlings. (522 aa)
COR47Dehydrin COR47. (265 aa)
IAA4Auxin-responsive protein IAA4; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin- responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. (186 aa)
ERD10Dehydrin ERD10. (260 aa)
ERD14Dehydrin ERD14; Intrinsically disordered protein acting as a chaperone. Prevents heat-induced aggregation and/or inactivation of various substrates. Binds to acidic phospholipid vesicles without affecting membrane fluidity. (185 aa)
GASA1Gibberellin-regulated protein 1; Gibberellin-regulated protein that may function in hormonal controlled steps of development such as seed germination, flowering and seed maturation; Belongs to the GASA family. (98 aa)
KNAT3Homeobox protein knotted-1-like 3; Belongs to the TALE/KNOX homeobox family. (431 aa)
KNAT4Homeobox protein knotted-1-like 4; Belongs to the TALE/KNOX homeobox family. (393 aa)
ABI1Protein phosphatase 2C 56; Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, osmotic water permeability of the plasma membrane (Pos), drought-induced resistance and rhizogenesis, response to glucose, high light stress, seed germination and inhibition of vegetative growth. During the stomatal closure regulation, modulates the inward calcium-channel permeability as well as the actin reorganization in guard cells in response to ABA. Involved in the resistance to the bacterial pathogen Pseudomonas syrin [...] (434 aa)
IAA1Auxin-responsive protein IAA1; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin- responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. (168 aa)
P5CSADelta-1-pyrroline-5-carboxylate synthase A; P5CS plays a key role in proline biosynthesis, leading to osmoregulation in plants; In the N-terminal section; belongs to the glutamate 5- kinase family. (717 aa)
CCA1Protein CCA1; Transcription factor involved in the circadian clock and in the phytochrome regulation. Binds to the promoter regions of APRR1/TOC1 and TCP21/CHE to repress their transcription. Binds to the promoter regions of CAB2A and CAB2B to promote their transcription. Represses both LHY and itself. (608 aa)
LTI65Low-temperature-induced 65 kDa protein; Belongs to the LTI78/LTI65 family. (619 aa)
ACO41-aminocyclopropane-1-carboxylate oxidase 4; Enzyme involved in the ethylene biosynthesis. May promote stem elongation by maximizing the extensibility cells, possibly by activating ethylene biosynthesis, in response to very-long-chain fatty acids (VLCFAs C20:0 to C30:0); Belongs to the iron/ascorbate-dependent oxidoreductase family. (323 aa)
RD29ALow-temperature-induced 78 kDa protein; Involved in responses to abiotic stresses. Regulates probably root elongation in cold conditions ; Belongs to the LTI78/LTI65 family. (710 aa)
RD22BURP domain protein RD22; Acts to suppress chlorophyll degradation under moisture stress. (392 aa)
GDH2-2Glutamate dehydrogenase 2; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (411 aa)
XTH4Xyloglucan endotransglucosylase/hydrolase protein 4; Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues. (296 aa)
TGA1Transcription factor TGA1; Transcriptional activator that binds specifically to the DNA sequence 5'-TGACG-3'. Recognizes ocs elements like the as-1 motif of the cauliflower mosaic virus 35S promoter. Binding to the as-1-like cis elements mediate auxin- and salicylic acid-inducible transcription. May be involved in the induction of the systemic acquired resistance (SAR) via its interaction with NPR1. Could also bind to the Hex-motif (5'- TGACGTGG-3') another cis-acting element found in plant histone promoters; Belongs to the bZIP family. (368 aa)
ZAT12Zinc finger protein ZAT12; Transcriptional repressor involved in light acclimation, cold and oxidative stress responses. May regulate a collection of transcripts involved in response to high-light, cold and oxidative stress. (162 aa)
ZAT5Zinc finger protein ZAT5; Probable transcription factor that may be involved in stress responses. (286 aa)
MSRB6Peptide methionine sulfoxide reductase B6; Catalyzes the reduction of methionine sulfoxide (MetSO) to methionine in proteins. Plays a protective role against oxidative stress by restoring activity to proteins that have been inactivated by methionine oxidation. MSRB family specifically reduces the MetSO R- enantiomer (By similarity). (153 aa)
XTH9Xyloglucan endotransglucosylase/hydrolase protein 9; Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues. Involved in internodal cell elongation; Belongs to the glycosyl hydrolase 16 family. XTH group 1 subfamily. (290 aa)
XTH6Probable xyloglucan endotransglucosylase/hydrolase protein 6; Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues (By similarity); Belongs to the glycosyl hydrolase 16 family. XTH group 1 subfamily. (292 aa)
RFS6Probable galactinol--sucrose galactosyltransferase 6; Transglycosidase operating by a ping-pong reaction mechanism. Involved in the synthesis of raffinose, a major soluble carbohydrate in seeds, roots and tubers (By similarity). (749 aa)
WRKY33Probable WRKY transcription factor 33; Transcription factor. Interacts specifically with the W box (5'-TTGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element. Involved in defense responses. Required for resistance to the necrotrophic fungal pathogen B.cinerea. Regulates the antagonistic relationship between defense pathways mediating responses to the bacterial pathogen P. syringae and the necrotrophic pathogen B.cinerea. Required for the phytoalexin camalexin synthesis following infection with B.cinerea. Acts as positive regulator of the camalexin biosynthetic ge [...] (519 aa)
NAC072NAC domain-containing protein 72; Transcription factors that bind specifically to the 5'- CATGTG-3' motif. (297 aa)
SZF1Zinc finger CCCH domain-containing protein 47; Involved in salt stress response. May positively modulate plant tolerance to salt stress. (580 aa)
RFS2Probable galactinol--sucrose galactosyltransferase 2; Transglycosidase operating by a ping-pong reaction mechanism. Involved in the synthesis of raffinose, a major soluble carbohydrate in seeds, roots and tubers (By similarity); Belongs to the glycosyl hydrolases 36 family. (773 aa)
ZAT10Zinc finger protein ZAT10; Transcriptional repressor involved in abiotic stress responses. Can repress the stress responsive genes DREB1A and LTI78. Probably involved in jasmonate (JA) early signaling response. May regulate the expression of the JA biosynthesis gene LOX3 and control the expression of TIFY10A/JAZ1, a key repressor in the JA signaling cascade. (227 aa)
SAUR62Auxin-responsive protein SAUR62; May promote auxin-stimulated organ elongation, such as hypocotyls, stamen filaments and petals; Belongs to the ARG7 family. (141 aa)
BZIP8Basic leucine zipper 8; Belongs to the bZIP family. (138 aa)
F14J22.4Leucine-rich repeat (LRR) family protein. (494 aa)
PMI2-2Mannose-6-phosphate isomerase 2; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (441 aa)
MJK13.11Aluminum induced protein with YGL and LRDR motifs. (253 aa)
LTP4Non-specific lipid-transfer protein 4; Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity). (112 aa)
LTP3Non-specific lipid-transfer protein 3; Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity). (115 aa)
BGLU16Beta-glucosidase 16. (514 aa)
ABF3ABSCISIC ACID-INSENSITIVE 5-like protein 6; Binds to the ABA-responsive element (ABRE). Mediates stress- responsive ABA signaling; Belongs to the bZIP family. ABI5 subfamily. (454 aa)
ACP4Acyl carrier protein 4, chloroplastic; Carrier of the growing fatty acid chain in fatty acid biosynthesis that plays a major role in the biosynthesis of fatty acids in leaves. Required for the biosynthesis of chloroplast photosynthetic membrane lipids such as monogalactosyldiacylglycerol, digalactosyldiacylglycerol and phosphatidylglycerol. Is essential for the biosynthesis of the cuticular wax and cutin polymers in leaves, and for the establishment of systemic acquired resistance (SAR). (137 aa)
SAUR16SAUR-like auxin-responsive protein family. (105 aa)
T4E14.72-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein. (148 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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