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MKK2 MKK2 AMT1-3 AMT1-3 UGT73C5 UGT73C5 CPK27 CPK27 HAI3 HAI3 SK1 SK1 MEE39 MEE39 SPHK2 SPHK2 F3F9.9 F3F9.9 AT1G78800 AT1G78800 SPS4 SPS4 ABI2 ABI2 LRR-RLK-4 LRR-RLK-4 F20D22.2 F20D22.2 F26P21.70 F26P21.70 NRT2.1 NRT2.1 AHA2 AHA2 AHA1 AHA1 SRK2A SRK2A ABI1 ABI1 PP2CA PP2CA AMT1-1 AMT1-1 NPF6.3 NPF6.3 MPK7 MPK7 SPHK1 SPHK1 SPS3-2 SPS3-2 F2P9.21 F2P9.21 SPS1-2 SPS1-2 PUP18 PUP18 F7A10.8 F7A10.8 HAB1 HAB1 NRT3.1 NRT3.1 CRRSP59 CRRSP59 SAG113 SAG113 AHG1 AHG1 POLL POLL SPS2-2 SPS2-2 G6PD5 G6PD5 ATL80 ATL80 HAB2 HAB2 AIP1 AIP1 LCBK1 LCBK1 CRRSP29 CRRSP29 CIPK2 CIPK2 GSH3 GSH3
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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MKK2Mitogen-activated protein kinase kinase 2; MEKK1, MKK1/MKK2 and MPK4 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity. Plays a role in abiotic stress tolerance and plant disease resistance through activation of MPK4 and MPK6 by phosphorylation. Acts redundantly with MKK1. (363 aa)
AMT1-3Ammonium transporter 1 member 3; Ammonium transporter probably involved in ammonium uptake from the soil. Contributes with AMT1-1 to the overall ammonium uptake capacity in roots under nitrogen-deficiency conditions. (498 aa)
UGT73C5UDP-glycosyltransferase 73C5; Specifically catalyzes 23-O-glucosylation of brassinosteroids, resulting probably in their inactivation. Also, involved in the O-glucosylation of trans-zeatin and dihydrozeatin. Active in vitro on cis-zeatin, dihydrozeatin-9-N-Glc, and olomoucine. Also involved in the detoxification of the Fusarium mycotoxin deoxynivalenol by the transfer of glucose from UDP-glucose to the hydroxyl group at C-3. Possesses low quercetin 7-O-glucosyltransferase and 4'-O-glucosyltransferase activities in vitro. Belongs to the UDP-glycosyltransferase family. (495 aa)
CPK27Calcium-dependent protein kinase 27; May play a role in signal transduction pathways that involve calcium as a second messenger; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily. (485 aa)
HAI3Probable protein phosphatase 2C 24. (362 aa)
SK1Shikimate kinase 1, chloroplastic; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate. (303 aa)
MEE39Probable LRR receptor-like serine/threonine-protein kinase MEE39; Receptor-like serine/threonine-kinase required during the endosperm development in seeds; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (878 aa)
SPHK2Sphingosine kinase 2; Involved in the production of sphingolipid metabolites. Phosphorylates sphingosine and various l sphingoid long-chain base (LCB) products, such as phytosphingosine (PHS, 4-hydroxysphinganine), 4-hydroxy-8-sphingenine, 4,8-sphingadienine and D-erythro- dihydrosphingosine, but has a very few activity toward D,L- threo- dihydrosphingosine. Is required for abscisic acid (ABA) signaling that mediates stomatal closure, inhibition of seed germination and root elongation. May function upstream of PLDALPHA1 and phosphatidic acid (PA) in an amplification response to ABA tha [...] (481 aa)
F3F9.9Pectin lyase-like superfamily protein; Belongs to the glycosyl hydrolase 28 family. (404 aa)
AT1G78800UDP-Glycosyltransferase superfamily protein. (403 aa)
SPS4Probable sucrose-phosphate synthase 4; Plays a role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP- glucose and fructose- 6-phosphate. Involved in the regulation of carbon partitioning in the leaves of plants. May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf. Plays a role for sucrose availability that is essential for plant growth and fiber elongation; Belongs to the glycosyltransferase 1 family. (1050 aa)
ABI2Protein phosphatase 2C 77; Repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, osmotic water permeability of the plasma membrane (Pos), high light stress, response to glucose, seed germination and inhibition of vegetative growth. During the stomatal closure regulation, modulates the inward calcium-channel permeability as well as H(2)O(2) and oxidative burst in response to ABA and dehydration. Represses GHR1 and, to some extent, SRK2E/OST1, kinases involved in the regulation of SLAC1-dependent stomatal closure. Controls [...] (423 aa)
LRR-RLK-4Leucine-rich repeat protein kinase family protein. (773 aa)
F20D22.2Leucine-rich repeat protein kinase family protein. (1112 aa)
F26P21.70Probable protein phosphatase 2C 61. (326 aa)
NRT2.1High-affinity nitrate transporter 2.1; Involved in nitrate transport, but does not seem to be able to mediate transport by its own. Acts as a dual component transporter with NTR3.1. Acts as a repressor of lateral root initiation under high sucrose/low nitrate conditions. (530 aa)
AHA2ATPase 2, plasma membrane-type; The plasma membrane H(+) ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses. Involved in maintaining the membrane potential and delta-pH, together forming the plasma membrane protonmotive force (PMF) required for root and hypocotyl elongation and root tropism. Important for root growth and development during different nitrogen regimes. Forms a functional cation-translocating unit with CNGC17 tha [...] (948 aa)
AHA1ATPase 1, plasma membrane-type; The plasma membrane H(+) ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses. Forms a functional cation- translocating unit with CNGC17 that is activated by PSKR1/BAK1 and possibly other BAK1/RLK complexes. (949 aa)
SRK2ASerine/threonine-protein kinase SRK2A. (363 aa)
ABI1Protein phosphatase 2C 56; Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, osmotic water permeability of the plasma membrane (Pos), drought-induced resistance and rhizogenesis, response to glucose, high light stress, seed germination and inhibition of vegetative growth. During the stomatal closure regulation, modulates the inward calcium-channel permeability as well as the actin reorganization in guard cells in response to ABA. Involved in the resistance to the bacterial pathogen Pseudomonas syrin [...] (434 aa)
PP2CAProtein phosphatase 2C 37; Major negative regulator of abscisic acid (ABA) responses during seed germination and cold acclimation. Confers insensitivity to ABA. Modulates negatively the AKT2/3 activity, which mediates K(+) transport and membrane polarization during stress situations, probably by dephosphorylation. Prevents stomata closure by inactivating the S- type anion efflux channel SLAC1 and its activator SRK2E. Represses KIN10 activity by the specific dephosphorylation of its T-loop Thr-198, leading to a poststress inactivation of SnRK1 signaling. (399 aa)
AMT1-1Ammonium transporter 1 member 1; High affinity ammonium transporter probably involved in ammonium uptake from the soil, long-distance transport to the shoots and re-uptake of apoplastic ammonium that derives from photorespiration in shoots. Contributes with AMT1-3 to the overall ammonium uptake capacity in roots under nitrogen-deficiency conditions. Belongs to the ammonia transporter channel (TC 1.A.11.2) family. (501 aa)
NPF6.3Protein NRT1/ PTR FAMILY 6.3; Dual affinity nitrate transporter. Involved in proton- dependent nitrate uptake and in the regulation of the nitrate transporter NRT2.1. Acts also as a nitrate sensor that trigger a specific signaling pathway stimulating lateral root growth and seed germination. The uptake activity is not required for sensor function. Displays an auxin transport facilitation inhibited by high nitrate concentration. Required to prevent auxin accumulation in preemerged lateral root primordia and young lateral roots when external nitrate concentration is low or null. May be i [...] (590 aa)
MPK7Mitogen-activated protein kinase 7; MKK3-MPK7 module acts as a positive regulator of PR1 gene expression; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. (368 aa)
SPHK1Sphingosine kinase 1; Involved in the production of sphingolipid metabolites. Phosphorylates sphingosine and various sphingoid long-chain base (LCB) products, such as phytosphingosine (PHS, 4-hydroxysphinganine), 4- hydroxy-8-sphingenine, 4,8-sphingadienine, D-erythro-dihydrosphingosine and D,L-threo-dihydrosphingosine. Is required for abscisic acid (ABA) signaling that mediates stomatal closure, inhibition of seed germination and root elongation. May function upstream of PLDALPHA1 and phosphatidic acid (PA) in an amplification response to ABA that mediates stomatal closure. (485 aa)
SPS3-2Probable sucrose-phosphate synthase 3; Plays a role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP- glucose and fructose- 6-phosphate. Involved in the regulation of carbon partitioning in the leaves of plants. May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf. Plays a role for sucrose availability that is essential for plant growth and fiber elongation. (1062 aa)
F2P9.21Alpha/beta-Hydrolases superfamily protein. (704 aa)
SPS1-2Sucrose-phosphate synthase 1; Plays a major role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP- glucose and fructose- 6-phosphate. Involved in the regulation of carbon partitioning in the leaves of plants. May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf. Plays a role for sucrose availability that is essential for plant growth and fiber elongation. Required for nectar secretion. (1043 aa)
PUP18Probable purine permease 18. (390 aa)
F7A10.8Kinase with adenine nucleotide alpha hydrolases-like domain-containing protein. (676 aa)
HAB1Protein phosphatase 2C 16; Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, seed germination and inhibition of vegetative growth. Confers enhanced sensitivity to drought. Belongs to the PP2C family. (511 aa)
NRT3.1High-affinity nitrate transporter 3.1; Acts as a dual component transporter with NTR2.1. Required for high-affinity nitrate transport. Acts as a repressor of lateral root initiation. May be involved in targeting NRT2 proteins to the plasma membrane. Belongs to the NAR2 family. (210 aa)
CRRSP59Cysteine-rich repeat secretory protein 59. (287 aa)
SAG113Probable protein phosphatase 2C 78; Acts as negative regulator of abscisic acid (ABA) signaling for stomatal closure in leaves, and controls water loss during leaf senescence. Activated by the NAC029/NAP transcription factor during ABA signaling in senescing leaves. Functions as negative regulator of osmotic stress and ABA signaling. Acts as negative regulator of response to drought. Belongs to the PP2C family. (413 aa)
AHG1Probable protein phosphatase 2C 75; Negative regulator of abscisic acid (ABA) responses during seed germination; Belongs to the PP2C family. (416 aa)
POLLDNA polymerase lambda; Repair polymerase involved in base excision repair (BER) and responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity (By similarity). Involved in the repair of transposon-induced DNA double strand breaks (DSBs). Involved in repair of UV-B- mediated DNA damage during seedling development through an excision repair mechanism. Involved the repair of DSBs induced by high salinity and DNA cross-linking agent. Functions via the [...] (529 aa)
SPS2-2Probable sucrose-phosphate synthase 2; Plays a role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP- glucose and fructose- 6-phosphate. Involved in the regulation of carbon partitioning in the leaves of plants. May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf. Plays a role for sucrose availability that is essential for plant growth and fiber elongation. Required for nectar secretion. (1047 aa)
G6PD5Glucose-6-phosphate 1-dehydrogenase 5, cytoplasmic; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis which are involved in membrane synthesis and cell division. (516 aa)
ATL80RING-H2 finger protein ATL80; May be involved in the early steps of the plant defense signaling pathway; Belongs to the RING-type zinc finger family. ATL subfamily. (197 aa)
HAB2Protein phosphatase 2C 7; Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, seed germination and inhibition of vegetative growth. (511 aa)
AIP1Protein phosphatase 2C 3; Involved in the negative regulation of the K(+) potassium channel AKT1 by its dephosphorylation, antagonistically to CIPK proteins (e.g. CIPK23). Functions as positive regulator of abscisic acid-mediated cell signaling during seedling growth. Involved in the regulation of seed dormancy. Acts as negative regulator of seed dormancy by inhibiting abscisic signaling and subsequently activating gibberellic acid signaling ; Belongs to the PP2C family. (442 aa)
LCBK1Sphingoid long-chain bases kinase 1; Involved in the production of sphingolipid metabolites. Active on sphingosine, phytosphingosine (PHS, 4-hydroxysphinganine), D- erythro-dihydrosphingosine, D-erythro-sphingosine and trans-4, trans-8- sphingadienine, an LCB found exclusively in plants, but not on N- acetyl-dihydrosphingosine (C2-dihydroceramide) and D-threo- dihydrosphingosine. (763 aa)
CRRSP29Cysteine-rich repeat secretory protein 29. (256 aa)
CIPK2CBL-interacting serine/threonine-protein kinase 2; CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity). (456 aa)
GSH3Probable glutamate dehydrogenase 3; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (411 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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