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SULTR1;2 SULTR1;2 FRO3 FRO3 MEE29 MEE29 SULTR3;2 SULTR3;2 MPPalpha2 MPPalpha2 SULTR2;1 SULTR2;1 POT2 POT2 NPF5.5 NPF5.5 BAG6 BAG6 ARAC7 ARAC7 OPT7 OPT7 CAM1 CAM1 CAM2 CAM2 STP1 STP1 TIP1-1 TIP1-1 CML10 CML10 SRP-54C SRP-54C ACBP6 ACBP6 CAM7 CAM7 CLC-A CLC-A CLC-B CLC-B CLC-D CLC-D FRO2 FRO2 CAM6 CAM6 PDS PDS PARP2 PARP2 KOR KOR FRO7 FRO7 TIP1-2 TIP1-2 PER64 PER64 NHX2 NHX2 Dl4720W Dl4720W YSL2 YSL2 ANTR3 ANTR3 CLC-E CLC-E PHT1-5 PHT1-5 SULTR4;2 SULTR4;2 MSSP2 MSSP2 sks17 sks17 FRO6 FRO6 CLC-F CLC-F FRO8 FRO8 PHT1-1 PHT1-1 PLT5 PLT5 DEG15 DEG15 RH38 RH38 GPT2 GPT2 SULTR3;5 SULTR3;5 MSSP1 MSSP1 PHT1-4 PHT1-4 CP1 CP1 SUC4 SUC4 SULTR1;3 SULTR1;3 Q9LDF5_ARATH Q9LDF5_ARATH SULTR4;1 SULTR4;1 ABCB19 ABCB19 FMO FMO NRT2.5 NRT2.5 SULTR3;4 SULTR3;4 POT8 POT8 POT5 POT5 ANTR5 ANTR5 MRS2-2 MRS2-2 SLAH3 SLAH3 FRO5 FRO5 OPT4 OPT4 YUC10 YUC10 HIPP17 HIPP17 F17A8.20 F17A8.20 RBG2 RBG2 SULTR3;1 SULTR3;1 SUV3 SUV3 SULTR1;1 SULTR1;1 ABCB1 ABCB1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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co-expression
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SULTR1;2Sulfate transporter 1.2; High-affinity H(+)/sulfate cotransporter that mediates the uptake of the environmental sulfate by plant roots. Plays a central role in the regulation of sulfate assimilation. Unable to transport molybdate; Belongs to the SLC26A/SulP transporter (TC 2.A.53.1) family. (653 aa)
FRO3Ferric reduction oxidase 3, mitochondrial; Ferric chelate reductase involved in iron reduction in roots. May participate in the transport of electrons to a Fe(3+) ion via FAD and heme intermediates. (717 aa)
MEE29Probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH6; May be involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily. PRP2 sub-subfamily. (1044 aa)
SULTR3;2Sulfate transporter 3.2; H(+)/sulfate cotransporter that may play a role in the regulation of sulfate assimilation. (646 aa)
MPPalpha2Probable mitochondrial-processing peptidase subunit alpha-2, chloroplastic/mitochondrial; Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. Belongs to the peptidase M16 family. (499 aa)
SULTR2;1Sulfate transporter 2.1; Low-affinity H(+)/sulfate cotransporter that may be involved in root-to-shoot translocation of sulfate. Plays a central role in the regulation of sulfate assimilation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (677 aa)
POT2Potassium transporter 2; Low-affinity potassium transporter. Could mediate the potassium-dependent cell expansion in growing tissues. (794 aa)
NPF5.5Protein NRT1/ PTR FAMILY 5.5; Belongs to the PTR2/POT transporter (TC 2.A.17) family. (521 aa)
BAG6BAG family molecular chaperone regulator 6; Co-chaperone that regulates diverse cellular pathways, such as programmed cell death and stress responses. Involved in plant basal resistance. Involved in basal heat response through the regulation of the heat induced small HSP (sHSP) transcriptional cascade. (1043 aa)
ARAC7Rac-like GTP-binding protein ARAC7; Acts as a negative regulator of abscisic acid (ABA) responses. (209 aa)
OPT7Oligopeptide transporter 7; Involved in the translocation of tetra- and pentapeptides across the cellular membrane in an energy-dependent manner. May also transport cadmium complexes; Belongs to the oligopeptide OPT transporter (TC 2.A.67.1) family. (766 aa)
CAM1Calmodulin-1; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
CAM2Calmodulin-2; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
STP1Sugar transport protein 1; Major hexose transporter. Mediates an active uptake of hexoses, by sugar/hydrogen symport. Can transport glucose, 3-O- methylglucose, fructose, xylose, mannose, galactose, fucose, 2- deoxyglucose and arabinose. Confers sensitivity to galactose in seedlings. (522 aa)
TIP1-1Aquaporin TIP1-1; Water channel required to facilitate the transport of water, diffusion of amino acids and/or peptides from the vacuolar compartment to the cytoplasm. Does not promote glycerol permeability. May play a role in the control of cell turgor and cell expansion. Its function is impaired by Hg(2+). May be involved in a vesicle-based metabolite routing through or between pre-vacuolar compartments and the central vacuole. Transports urea in yeast cells in a pH-independent manner. Transports H(2)O(2) in yeast cells. (251 aa)
CML10Calmodulin-like protein 10; Potential calcium sensor. (191 aa)
SRP-54CSignal recognition particle 54 kDa protein 3; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). (495 aa)
ACBP6Acyl-CoA-binding domain-containing protein 6; Binds medium- and long-chain acyl-CoA esters with very high affinity. May function as an intracellular carrier of acyl-CoA esters. Confers resistance to cold and freezing. Interacts with phosphatidylcholine and derivatives, but not phosphatidic acid and lysophosphatidylcholine. May be involved in phospholipid metabolism. Belongs to the ACBP family. (92 aa)
CAM7Calmodulin-7; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Activates MPK8 in vitro. (149 aa)
CLC-AChloride channel protein CLC-a; Voltage-gated chloride channel that could play a role in the regulation of nitrate content. (775 aa)
CLC-BChloride channel protein CLC-b; Voltage-gated chloride channel; Belongs to the chloride channel (TC 2.A.49) family. (780 aa)
CLC-DChloride channel protein CLC-d; Voltage-gated chloride channel; Belongs to the chloride channel (TC 2.A.49) family. (792 aa)
FRO2Ferric reduction oxidase 2; Flavocytochrome that transfers electrons across the plasma membrane to reduce ferric iron chelates to form soluble ferrous iron in the rhizosphere. May be involved in the delivery of iron to developing pollen grains. Acts also as a copper-chelate reductase. Involved in glycine betaine-mediated chilling tolerance and reactive oxygen species accumulation. (725 aa)
CAM6Calmodulin-6; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
PDS15-cis-phytoene desaturase, chloroplastic/chromoplastic; Converts phytoene into zeta-carotene via the intermediary of phytofluene by the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene with a concomitant isomerization of two neighboring double bonds at the C9 and C9' positions from trans to cis; Belongs to the carotenoid/retinoid oxidoreductase family. (566 aa)
PARP2Poly [ADP-ribose] polymerase 2; Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (By similarity). (637 aa)
KOREndoglucanase 25; Required for cellulose microfibrils formation. Involved in cell wall assembly during cell elongation and cell plate maturation in cytokinesis. Required for secondary cell wall formation in the developing xylem. May cycle through different intracellular compartments, including plasma membrane. (621 aa)
FRO7Ferric reduction oxidase 7, chloroplastic; Ferric chelate reductase involved in iron mobilization from the cytosol into the chloroplast. May participate in the transport of electrons to a Fe(3+) ion via FAD and heme intermediates. Might be involved iron homeostasis in trichomes. (747 aa)
TIP1-2Aquaporin TIP1-2; Water channel required to facilitate the transport of water across cell membrane. May be involved in the osmoregulation in plants under high osmotic stress such as under a high salt condition. Transports urea in yeast cells in a pH-independent manner. Transports H(2)O(2) in yeast cells. (253 aa)
PER64Peroxidase 64; Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue; Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily. (317 aa)
NHX2Sodium/hydrogen exchanger 2; Acts in low affinity electroneutral exchange of protons for cations such as Na(+) or K(+) across membranes. May also exchange Li(+) and Cs(+) with a lower affinity. Involved in vacuolar ion compartmentalization necessary for cell volume regulation and cytoplasmic Na(+) detoxification. (546 aa)
Dl4720WOxidoreductase family protein. (368 aa)
YSL2Metal-nicotianamine transporter YSL2; May be involved in the lateral transport of nicotianamine- chelated metals in the vasculature. (664 aa)
ANTR3Probable anion transporter 3, chloroplastic; Inorganic phosphate and probable anion transporter. Belongs to the major facilitator superfamily. Sodium/anion cotransporter (TC 2.A.1.14) family. (512 aa)
CLC-EChloride channel protein CLC-e; Voltage-gated chloride channel; Belongs to the chloride channel (TC 2.A.49) family. (710 aa)
PHT1-5Probable inorganic phosphate transporter 1-5; High-affinity transporter for external inorganic phosphate. (542 aa)
SULTR4;2Probable sulfate transporter 4.2; H(+)/sulfate cotransporter that may play a role in the regulation of sulfate assimilation. (677 aa)
MSSP2Monosaccharide-sensing protein 2. (729 aa)
sks17AT5g66920/MUD21_18. (546 aa)
FRO6Ferric reduction oxidase 6; Ferric chelate reductase involved in iron uptake by shoot and leaf cells. May participate in the transport of electrons to a Fe(3+) ion via FAD and heme intermediates. (738 aa)
CLC-FChloride channel protein CLC-f; Voltage-gated chloride channel. (781 aa)
FRO8Ferric reduction oxidase 8, mitochondrial; Ferric chelate reductase probably involved in iron reduction in leaf veins for transport. May participate in the transport of electrons to a Fe(3+) ion via FAD and heme intermediates. (728 aa)
PHT1-1Inorganic phosphate transporter 1-1; High-affinity transporter for external inorganic phosphate. Acts as a H(+):phosphate symporter in both low- and high-Pi conditions. Confers sensitivity to arsenate. (524 aa)
PLT5Polyol transporter 5; Plasma membrane broad-spectrum sugar-proton symporter. Mediates the uptake of linear polyols such as sorbitol, xylitol, erythritol or glycerol. Can transport the cyclic polyol myo-inositol and different hexoses, pentoses (including ribose), tetroses and sugar alcohols. (539 aa)
DEG15Glyoxysomal processing protease, glyoxysomal; Trypsin-like serine endopeptidase involved in the processing of glyoxysomal higher molecular weight precursor. The dimeric form carries out the specific cleavages needed to remove PTS2-containing presequences, whereas the monomeric form degrades the removed presequences and misfolded proteins (Probable). Not required for degradation of glyoxylate cycle enzymes during seedling development. (709 aa)
RH38DEAD-box ATP-dependent RNA helicase 38; ATP-dependent RNA helicase essential for mRNA export from the nucleus. Plays an important role in the positive regulation of CBF/DREB transcription factors. (496 aa)
GPT2Glucose-6-phosphate/phosphate translocator 2, chloroplastic; Glucose 6-phosphate (Glc6P) transporter. Transports also inorganic phosphate, 3-phosphoglycerate, triose phosphates and, to a leser extent, phosphoenolpyruvate. Responsible for the transport of Glc6P into plastids of heterotrophic tissues where it can be used as a carbon source for starch biosynthesis, as substrate for fatty acid biosynthesis or as substrate for NADPH generation via the oxidative pentose phosphate pathway (OPPP). Required for dynamic acclimation of photosynthesis; Belongs to the TPT transporter family. GPT (T [...] (388 aa)
SULTR3;5Probable sulfate transporter 3.5; H(+)/sulfate cotransporter that may play a role in the regulation of sulfate assimilation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (634 aa)
MSSP1Monosaccharide-sensing protein 1. (734 aa)
PHT1-4Inorganic phosphate transporter 1-4; High-affinity transporter for external inorganic phosphate. Acts as a H(+):phosphate symporter in both low- and high-Pi conditions. Confers sensitivity to arsenate. (534 aa)
CP1Calcium-binding protein CP1; Binds calcium in vitro. (160 aa)
SUC4Sucrose transport protein SUC4; Responsible for the transport of sucrose into the cell, with the concomitant uptake of protons (symport system). Can also transport maltose at a lesser rate. May also transport biotin. Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2.4) family. (510 aa)
SULTR1;3Sulfate transporter 1.3; High-affinity H(+)/sulfate cotransporter that mediates the loading of sulfate into the sieve tube. Plays a central role in the regulation of sulfate assimilation. (656 aa)
Q9LDF5_ARATH3-hydroxybutyryl-CoA dehydrogenase-like protein. (294 aa)
SULTR4;1Sulfate transporter 4.1, chloroplastic; H(+)/sulfate cotransporter that may play a role in the regulation of sulfate assimilation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (685 aa)
ABCB19ABC transporter B family member 19; Auxin efflux transporter that acts as a negative regulator of light signaling to promote hypocotyl elongation. Mediates the accumulation of chlorophyll and anthocyanin, as well as the expression of genes in response to light. Participates in auxin efflux and thus regulates the polar auxin basipetal transport (from auxin-producing leaves to auxin-sensitive tissues, and from root tips to root elongating zone). Involved in diverse auxin-mediated responses including gravitropism, phototropism and lateral root formation. (1252 aa)
FMOFlavin-containing monooxygenase FMO GS-OX-like 2; Catalyzes the conversion of methylthioalkyl glucosinolates of any chain length into methylsulfinylalkyl glucosinolates. Belongs to the FMO family. (465 aa)
NRT2.5High affinity nitrate transporter 2.5; Nitrate transporter involved in the constitutive high- affinity transport system (cHATS) under long-term N starvation conditions. Predominantly expressed in roots of nitrate-deprived plants as a 150 kDa molecular complex with NRT3.1 representing the major contributor to cHATS influx. The principal role of this cHATS is to enable roots previously deprived of nitrate to absorb this ion and initiate induction of nitrate-inducible genes. Not involved in transfer of nitrate from roots to shoots. Contributes to phloem loading of nitrate in shoots during [...] (502 aa)
SULTR3;4Probable sulfate transporter 3.4; H(+)/sulfate cotransporter that may play a role in the regulation of sulfate assimilation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (653 aa)
POT8Potassium transporter 8; Probable potassium transporter; Belongs to the HAK/KUP transporter (TC 2.A.72.3) family. (781 aa)
POT5Potassium transporter 5; High-affinity potassium transporter. Can also transport rubidium and cesium. Is essential with AKT1 for high-affinity potassium uptake in roots during seedling establishment and postgermination growth under low potassium conditions. Mediates potassium uptake by plant roots in response to low potassium conditions, by a calcium-, CBL-, and CIPK-dependent pathway. Positively regulated by the calcium sensors calcineurin B-like genes CBL1, CBL8, CBL9 and CBL10, and by phosphorylation by CIPK23 ; Belongs to the HAK/KUP transporter (TC 2.A.72.3) family. (785 aa)
ANTR5Probable anion transporter 5; Inorganic phosphate and probable anion transporter. (432 aa)
MRS2-2Magnesium transporter MRS2-2; Low-affinity magnesium transporter that mediates the influx of magnesium. Plays a crucial role in male gametophyte development and male fertility; Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family. (394 aa)
SLAH3S-type anion channel SLAH3; Slow, weak voltage-dependent S-type anion efflux channel involved in maintenance of anion homeostasis. Binds to the highly selective inward-rectifying potassium channel KAT1 and inhibits its activity. Functions as an essential negative regulator of inward potassium channels in guard cells. Essential for the efficient stomatal closure and opening in guard cells. (635 aa)
FRO5Ferric reduction oxidase 5; Ferric chelate reductase probably involved in iron reduction in shoots. May participate in the transport of electrons to a Fe(3+) ion via FAD and heme intermediates. May act in iron metabolism in reproductive organs. May function as root surface cupric chelate reductase and participate in the reduction of Cu(2+), for Cu(+) acquisition via Cu(+) transporters in response to copper deficiency. (707 aa)
OPT4Oligopeptide transporter 4; Involved in the translocation of tetra- and pentapeptides across the cellular membrane in an energy-dependent manner. (729 aa)
YUC10Probable indole-3-pyruvate monooxygenase YUCCA10; Involved in auxin biosynthesis. Belongs to the FMO family. (383 aa)
HIPP17Heavy metal-associated isoprenylated plant protein 17; Probable heavy-metal-binding protein. (264 aa)
F17A8.20Uncharacterized oxidoreductase At4g09670. (362 aa)
RBG2Glycine-rich RNA-binding protein 2, mitochondrial; Plays a role in RNA transcription or processing during stress. Binds RNAs and DNAs sequence with a preference to single- stranded nucleic acids. Displays strong affinity to poly(U) sequence. Exerts cold and freezing tolerance, probably by exhibiting an RNA chaperone activity during the cold and freezing adaptation process. Belongs to the GR-RBP family. (158 aa)
SULTR3;1Sulfate transporter 3.1; H(+)/sulfate cotransporter that may play a role in the regulation of sulfate assimilation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (658 aa)
SUV3DExH-box ATP-dependent RNA helicase DExH16, mitochondrial; Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degra [...] (571 aa)
SULTR1;1Sulfate transporter 1.1; High-affinity H(+)/sulfate cotransporter that mediates the uptake of the environmental sulfate by plant roots under low-sulfur conditions. Plays a central role in the regulation of sulfate assimilation. (649 aa)
ABCB1ABC transporter B family member 1; Auxin efflux transporter that acts as a negative regulator of light signaling to promote hypocotyl elongation. Mediates the accumulation of chlorophyll and anthocyanin, as well as the expression of genes in response to light. Participates directly in auxin efflux and thus regulates the polar (presumably basipetal) auxin transport (from root tips to root elongating zone). Transports also some auxin metabolites such as oxindoleacetic acid and indoleacetaldehyde. Involved in diverse auxin-mediated responses including gravitropism, phototropism and latera [...] (1286 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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