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dl3345c dl3345c F1N19.18 F1N19.18 NAC072 NAC072 CML46 CML46 BAP1 BAP1 BON1 BON1 GILP GILP ACT2 ACT2 NAC019 NAC019 SARD1 SARD1 CP1 CP1 NFXL2 NFXL2 CML37 CML37 CNGC13 CNGC13 NAC055 NAC055 FMO1 FMO1 MPK11 MPK11 MUF8.3 MUF8.3 HIPP14 HIPP14 GH3.12 GH3.12 EXO70A1 EXO70A1 CML45 CML45 PAD4 PAD4 ICS1 ICS1 SNAP33 SNAP33 F22C12.10 F22C12.10 NUDT5 NUDT5 SOBIR1 SOBIR1 WRKY46 WRKY46 F22D22.22 F22D22.22 EIL1 EIL1 T8P19.160 T8P19.160 CML47 CML47 NUDT7 NUDT7 EDS1 EDS1 SYP122 SYP122 RLP49 RLP49 DREB1C DREB1C ADR1-L1 ADR1-L1 EGC2 EGC2 T14L22.10 T14L22.10 CBP60G CBP60G EIN3 EIN3 CAM1 CAM1 CAM2 CAM2 PR5 PR5 CML10 CML10 TGA2 TGA2 IAN8 IAN8 CAM7 CAM7 NPR1 NPR1 CAM6 CAM6 F20M13.120 F20M13.120 NPR4 NPR4 SCO3 SCO3 CRK45 CRK45 NPR3 NPR3 AGP5 AGP5 WRKY28 WRKY28
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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experimentally determined
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dl3345cProbable disease resistance protein At4g14610; Probable disease resistance protein; Belongs to the disease resistance NB-LRR family. (719 aa)
F1N19.18Transducin/WD40 repeat-like superfamily protein. (647 aa)
NAC072NAC domain-containing protein 72; Transcription factors that bind specifically to the 5'- CATGTG-3' motif. (297 aa)
CML46Probable calcium-binding protein CML46; Potential calcium sensor. (204 aa)
BAP1BON1-associated protein 1; Negative regulator of cell death and defense responses. Exhibits calcium-dependent phospholipid binding properties. (192 aa)
BON1Protein BONZAI 1; Negative regulator of cell death and defense responses. Negative regulator of several R genes, including SNC1. May have effects in promoting growth and development. May function in membrane trafficking and in fusion of vesicles with plasma membrane at low temperature. Exhibits calcium-dependent phospholipid binding properties. (578 aa)
GILPGSH-induced LITAF domain protein; Acts as a membrane anchor, bringing other regulators of programmed cell death (PCD) to the plasma membrane. Negatively regulates hypersensitive cell death; Belongs to the CDIP1/LITAF family. (134 aa)
ACT2Actin-2; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the vegetative actins. (377 aa)
NAC019NAC domain-containing protein 19; Transcription factors that bind specifically to the 5'- CATGTG-3' motif. (317 aa)
SARD1Protein SAR DEFICIENT 1; Transcription activator that binds DNA in a sequence-specific manner, 5'-GAAATTTTGG-3', to promote the expression of target genes. Recruited to the promoter of ICS1 and other defense-related genes (e.g. PR1 and SID2) in response to both biotic (e.g. Pseudomonas syringae pv. maculicola ES4326) and abiotic stresses (e.g. UV-B), thus triggering slow defense responses by stimulating salicylic acid (SA) biosynthesis. Required for basal and systemic acquired resistance to P. syringae pv. maculicola and Hyaloperonospora arabidopsidis. Belongs to the plant ACBP60 prote [...] (451 aa)
CP1Calcium-binding protein CP1; Binds calcium in vitro. (160 aa)
NFXL2NF-X1-type zinc finger protein NFXL2; Probable transcriptional regulator. May mediate E2- or E3- dependent ubiquitination. Required to gate light sensitivity during the night. Regulates the speed of the clock by acting in the feedback loop between CCA1, LHY and APRR1/TOC1. Promotes the expression of CCA1 at night but not by days. This activational effect is enhanced by interaction with ADO1/ZTL. Association with ADO1/ZTL is not leading to the degradation of NFXL2. Confers sensitivity to osmotic stress such as high salinity. Prevents H(2)O(2) production and abscisic acid accumulation. P [...] (883 aa)
CML37Calcium-binding protein CML37; Potential calcium sensor that binds calcium in vitro. (185 aa)
CNGC13Putative cyclic nucleotide-gated ion channel 13; Putative cyclic nucleotide-gated ion channel; Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. (696 aa)
NAC055NAC domain-containing protein 55; Transcription factors that bind specifically to the 5'- CATGTG-3' motif. (317 aa)
FMO1Probable flavin-containing monooxygenase 1; Required for the establishment of systemic acquired resistance (SAR). Not involved in local defense mechanisms. Confers a salicylic acid-dependent (SA) resistance to virulent pathogens such as P.syringae pv tomato and H.parasitica. (530 aa)
MPK11Mitogen-activated protein kinase 11. (369 aa)
MUF8.3Disease resistance protein (TIR-NBS-LRR class) family. (1068 aa)
HIPP14Heavy metal-associated isoprenylated plant protein 14; Probable heavy-metal-binding protein. Belongs to the HIPP family. (126 aa)
GH3.124-substituted benzoates-glutamate ligase GH3.12; Catalyzes the conjugation of specific amino acids (e.g. Glu and possibly His, Lys, and Met) to their preferred acyl substrates (e.g. 4-substituted benzoates), in a magnesium ion- and ATP-dependent manner. Can use 4-substituted benzoates such as 4-aminobenzoate (pABA), 4-fluorobenzoate and 4-hydroxybenzoate (4-HBA), and, to a lesser extent, benzoate, vanillate and trans-cinnamate, but not 2-substituted benzoates and salicylic acid (SA), as conjugating acyl substrates. Involved in both basal and induced resistance in a SA-dependent manner. [...] (575 aa)
EXO70A1Exocyst complex component EXO70A1; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane during regulated or polarized secretion. Involved in polarized cell growth and organ morphogenesis. Involved in polarized cell growth and organ morphogenesis. During cytokinesis, involved in cell plate initiation, cell plate maturation and formation of new primary cell wall. Participates in polarized pectin delivery required for the polarized development of the mucilage-producing volcano cells of the seed coat. Involved in the recycli [...] (638 aa)
CML45Probable calcium-binding protein CML45; Potential calcium sensor. (194 aa)
PAD4Lipase-like PAD4; Probable lipase required downstream of MPK4 for accumulation of the plant defense-potentiating molecule, salicylic acid, thus contributing to the plant innate immunity against invasive biotrophic pathogens and to defense mechanisms upon recognition of microbe- associated molecular patterns (MAMPs). Participates in the regulation of various molecular and physiological processes that influence fitness. Together with SG101, required for programmed cell death (PCD) triggered by NBS-LRR resistance proteins (e.g. RPS4, RPW8.1 and RPW8.2) in response to the fungal toxin fumo [...] (541 aa)
ICS1Isochorismate synthase 1, chloroplastic; Involved in the synthesis of salicylic acid (SA) required for both local and systemic acquired resistance (LAR and SAR) while SA synthesized through the phenylalanine ammonium lyase (PAL) pathway seems to potentiate plant cell death. Also involved in phylloquinone (vitamin K1) synthesis. Has no isochorismate pyruvate lyase (IPL) activity. (569 aa)
SNAP33SNAP25 homologous protein SNAP33; t-SNARE involved in diverse vesicle trafficking and membrane fusion processes, including cell plate formation. May function in the secretory pathway; Belongs to the SNAP-25 family. (300 aa)
F22C12.10WRKY transcription factor. (646 aa)
NUDT5Nudix hydrolase 5; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives. (302 aa)
SOBIR1Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1; Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Acting as a counterplayer of BIR1, promotes the activation of plant defense and cell death. Component of the RLP23-SOBIR1-BAK1 complex that mediates NLP-triggered immunity. Functions as an inhibitor/regulator of abscission, probably by regulating membrane trafficking during abscission. (641 aa)
WRKY46Probable WRKY transcription factor 46; Transcription factor involved in the regulation of osmotic stress responses and stomatal movement. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Positive regulator of EDS1-dependent defense against E.amylovora. Together with WRKY70 and WRKY53, promotes resistance to P.syringae, probably by enhancing salicylic acid (SA)- dependent genes. Contributes to the suppression of jasmonic acid (MeJA)-induced expression of PDF1.2. Together with WRKY54 and WRKY70, prom [...] (295 aa)
F22D22.22Acyl-CoA N-acyltransferases (NAT) superfamily protein. (188 aa)
EIL1ETHYLENE INSENSITIVE 3-like 1 protein; Probable transcription factor acting as a positive regulator in the ethylene response pathway. Could bind the primary ethylene response element present in the ETHYLENE-RESPONSE-FACTOR1 promoter. Belongs to the EIN3 family. (584 aa)
T8P19.160UPF0496 protein At3g48650. (277 aa)
CML47Probable calcium-binding protein CML47; Potential calcium sensor. (183 aa)
NUDT7Nudix hydrolase 7; Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can use both NADH and ADP-ribose as substrates, but not 8- oxo-dGTP, cyclic ADP-ribose, GDP-manose, UDP-glucose, ATP, or GTP. Exerts negative control of EDS1 signaling. (282 aa)
EDS1Protein EDS1; Positive regulator of basal resistance and of effector- triggered immunity specifically mediated by TIR-NB-LRR (TNL) resistance proteins. Disruption by bacterial effector of EDS1-TIR-NB-LRR resistance protein interactions constitutes the first step in resistance activation. Acts redundantly with salicylic acid to regulate resistance gene-mediated signaling. Triggers early plant defenses and hypersensitive response independently of PAD4, and then recruits PAD4 to potentiate plant defenses through the accumulation of salicylic acid. Nuclear localization is essential for bas [...] (623 aa)
SYP122Syntaxin-122; Vesicle trafficking protein that functions in the secretory pathway. (341 aa)
RLP49Receptor-like protein 49; Belongs to the RLP family. (844 aa)
DREB1CDehydration-responsive element-binding protein 1C; Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates cold-inducible transcription. CBF/DREB1 factors play a key role in freezing tolerance and cold acclimation; Belongs to the AP2/ERF transcription factor family. ERF subfamily. (216 aa)
ADR1-L1Probable disease resistance protein At4g33300; Probable disease resistance protein; Belongs to the disease resistance NB-LRR family. (816 aa)
EGC2EG45-like domain containing protein 2; Plays a systemic role in water and solute homeostasis. (130 aa)
T14L22.10Probable LRR receptor-like protein kinase At1g51890; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (876 aa)
CBP60GCalmodulin-binding protein 60 G; Transcription activator that binds DNA in a sequence-specific manner, 5'-GAAATTTTGG-3', to promote the expression of target genes. Recruited to the promoter of ICS1 and other defense-related genes (e.g. PR1, PR2 and EDS5) in response to both biotic (e.g. Pseudomonas syringae pv. maculicola ES4326, P. syringae pv. tomato DC3000, and microbe- associated molecular patterns (MAMPs) such as flg22) and abiotic stresses (e.g. UV-B, drought and abscisic acid), thus triggering rapid defense responses by stimulating salicylic acid (SA) biosynthesis. Involved in b [...] (563 aa)
EIN3Protein ETHYLENE INSENSITIVE 3; Probable transcription factor acting as a positive regulator in the ethylene response pathway. Is required for ethylene responsiveness in adult plant tissues. Binds a primary ethylene response element present in the ETHYLENE-RESPONSE-FACTOR1 promoter with consequence to activate the transcription of this gene. (628 aa)
CAM1Calmodulin-1; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
CAM2Calmodulin-2; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
PR5Pathogenesis-related protein 5; Partially responsible for acquired pathogen resistance. (239 aa)
CML10Calmodulin-like protein 10; Potential calcium sensor. (191 aa)
TGA2Transcription factor TGA2; Transcriptional activator that binds specifically to the DNA sequence 5'-TGACG-3'. Recognizes ocs elements like the as-1 motif of the cauliflower mosaic virus 35S promoter. Binding to the as-1-like cis elements mediate auxin- and salicylic acid-inducible transcription. Required to induce the systemic acquired resistance (SAR) via the regulation of pathogenesis-related genes expression. Binding to the as- 1 element of PR-1 promoter is salicylic acid-inducible and mediated by NPR1. Could also bind to the C-boxes (5'-ATGACGTCAT-3') with high affinity. (330 aa)
IAN8Immune-associated nucleotide-binding protein 8. (353 aa)
CAM7Calmodulin-7; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Activates MPK8 in vitro. (149 aa)
NPR1Regulatory protein NPR1; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Key positive regulator of the SA-dependent signaling pathway that negatively regulates JA-dependent signaling pathway. Mediates the binding of TGA factors to the as-1 motif found in the pathogenesis-related PR-1 gene, leading to the transcriptional regulation of the gene defense. Controls the onset of systemic acquired resistance (SAR). Upon SAR induction, [...] (593 aa)
CAM6Calmodulin-6; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
F20M13.120Phospholipase-like protein (PEARLI 4) family protein. (523 aa)
NPR4Regulatory protein NPR4; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Involved in the regulation of basal defense responses against pathogens, and may be implicated in the cross-talk between the SA- and JA-dependent signaling pathways. (574 aa)
SCO3Protein SNOWY COTYLEDON 3; Probable microtubule-associated peroxisomal protein required for chloroplast biogenesis and for the formation of the prolamellar body and prothylakoids in etioplasts. Not involved in peroxisomal metabolism, including mobilization of storage compounds during germination, fatty acid beta-oxydation or photorespiration; Belongs to the QWRF family. (644 aa)
CRK45Cysteine-rich receptor-like protein kinase 45; Forms a complex with CRK36 that may negatively control abscisic acid (ABA) and osmotic stress signal transduction. Involved in plant response to ABA during seed germination, early seedling growth and responses to abiotic stresses by inducing the expression of ABA-responsive genes and stress-inducible genes. Acts as positive regulator in disease resistance, downstream of NPR1 and WRKY70. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CRK subfamily. (351 aa)
NPR3Regulatory protein NPR3; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Involved in the regulation of basal defense responses against pathogens. (586 aa)
AGP5Classical arabinogalactan protein 5; Proteoglycan that seems to be implicated in diverse developmental roles such as differentiation, cell-cell recognition, embryogenesis and programmed cell death; Belongs to the classical AGP family. (133 aa)
WRKY28WRKY transcription factor 28; Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element (By similarity); Belongs to the WRKY group II-c family. (318 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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