Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform; The B regulatory subunit may modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity). Required for the formation of the PP2A holoenzyme that positively regulates brassinosteroid signaling by dephosphorylating and activating BZR1.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1; Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Controls the expression of genes associated with innate immunity in the absence of pathogens or elicitors. Involved in brassinosteroid (BR) signal transduction. Phosphorylates BRI1. May be involved in changing the equilibrium between plasma membrane-located BRI1 homodimers and endocytosed BRI1- BAK1 heterodimers. Interaction with MSBP1 stimulates the endocytosis of BAK1 and suppresses brassinosteroid signaling. Acts in pathogen- associ [...]

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

BRI1 kinase inhibitor 1; Negative regulator of brassinosteroid signaling. When associated to the membrane, limits the interaction of BRI1 with BAK1 by binding to the kinase-inactive form of BRI1.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Protein BRASSINOSTEROID INSENSITIVE 1; Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development, including expression of light- and stress-regulated genes, promotion of cell elongation, normal leaf and chloroplast senescence, and flowering. Binds brassinolide, and less effectively castasterone, but not 2,3,22,23-O-tetramethylbrassinolide or ecdysone. May be involved in a feedback regulation of brassinosteroid biosynthesis. Pho [...]

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Serine/threonine-protein kinase BSK1; Serine/threonine kinase that acts as positive regulator of brassinosteroid (BR) signaling downstream of the receptor kinase BRI1. Mediates signal transduction from BRI1 by functioning as substrate of BRI1. Functions as a positive regulator of plant immunity. May be involved in the regulation of pattern-triggered immunity (PTI) downstream of the flagellin receptor FLS2. Possesses kinase activity in vitro. Kinase activity is required for its function in innate immunity.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Serine/threonine-protein phosphatase BSU1; Phosphatase that acts as a positive regulator of brassinosteroid (BR) signaling. Dephosphorylates BES1, a transcription factor that regulates the expression of BR-response genes, thereby playing an important role in the regulation of response to BRs. Inactivates the negative regulator of BR signaling ASK7/BIN2 by dephosphorylation at 'Tyr-200'.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Protein BRASSINAZOLE-RESISTANT 1; Transcriptional repressor that binds to the brassinosteroid (BR) response element (BRRE) 5'-CGTG(T/C)G-3' in gene promoter. Regulates positively the brassinosteroid-signaling pathway. Mediates downstream growth responses and negative feedback regulation of brassinosteroid biosynthesis. Promotes growth. Modulates ovule initiation and development by monitoring the expression of genes related to ovule development (e.g. HLL, ANT, and AP2).

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Protein BRASSINAZOLE-RESISTANT 2; Positive regulator of brassinosteroid (BR) signaling. Transcription factor that activates target gene expression by binding specifically to the DNA sequence 5'-CANNTG-3'(E box) through its N- terminal domain. Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BIM1, BIM2 or BIM3. The C- terminal domain is probably involved in transcriptional activation. Recruits the transcription elongation factor IWS1 to control BR- regulated gene expression. Forms a trimeric complex with IWS1 and ASHH2/SDG8 to regulate BR-reg [...]

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Cytochrome P450 85A1; Catalyzes the C6-oxidation step in brassinosteroids biosynthesis. Converts 6-deoxocastasterone to castasterone. May also convert 6-deoxoteasterone to teasterone, 3-dehydro-6-deoxoteasterone to 3-dehydroteasterone, and 6-deoxotyphasterol to typhasterol.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Cytochrome P450 85A2; Catalyzes the C6-oxidation step in brassinosteroids biosynthesis. Converts 6-deoxocastasterone to castasterone, and castasterone to brassinolide. May also convert 6-deoxoteasterone to teasterone, 3-dehydro-6-deoxoteasterone to 3-dehydroteasterone, and 6- deoxotyphasterol to typhasterol; Belongs to the cytochrome P450 family.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Cytochrome P450 90A1.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Cytochrome P450 90B1; Catalyzes the C22-alpha-hydroxylation step in brassinosteroids biosynthesis. Converts campestanol to 6- deoxocathasterone and 6-oxocampestanol to cathasterone.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

3-epi-6-deoxocathasterone 23-monooxygenase CYP90C1; Involved in brassinosteroid (BR) biosynthesis. Converts typhasterol to castasterone and 6-deoxotyphasterol to 6-deoxocastasterone. C-23 hydroxylase that converts directly (22S,24R)- 22-hydroxy-5-alpha-ergostan-3-one and 3-epi-6-deoxocathasterone to 3- dehydro-6-deoxoteasterone and 6-deoxotyphasterol, respectively. These C-23 hydroxylation shortcuts bypass campestanol, 6-deoxocathasterone, and 6-deoxoteasterone. Required for the regulation of polar elongation of leaf cells. Required for the longitudinal elongation of floral organs.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

3-epi-6-deoxocathasterone 23-monooxygenase CYP90D1; Involved in brassinosteroid (BR) biosynthesis. May convert teasterone to 3- dehydroteasterone, or 6-deoxoteasterone to 3-dehydro-6-deoxoteasterone. C-23 hydroxylase that converts directly (22S,24R)- 22-hydroxy-5-alpha-ergostan-3-one and 3-epi-6-deoxocathasterone to 3- dehydro-6-deoxoteasterone and 6-deoxotyphasterol, respectively. These C-23 hydroxylation shortcuts bypass campestanol, 6-deoxocathasterone, and 6-deoxoteasterone.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Delta(24)-sterol reductase; Plays a critical role in the general process of plant cell elongation. Involved in the synthesis of campesterol, an early precursor of brassinolide. Required for the conversion of 24- methylenecholesterol to campesterol and for the conversion of isofucosterol to sitosterol. Necessary for both the isomerization and reduction of 24-methylenecholesterol. Regulates indirectly phytochrome- mediated light responses through the modulation of brassinosteroid biosynthesis.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

7-dehydrocholesterol reductase; Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC). Lesions in the gene coding for the enzyme cause dwarfism; Belongs to the ERG4/ERG24 family.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Serine carboxypeptidase 24 chain A; Active serine carboxypeptidase with broad substrate preference, including basic and hydrophilic groups. Processes a protein involved in an early event in the brassinosteroid signaling pathway.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Delta(7)-sterol-C5(6)-desaturase 1; Involved in the biosynthesis of sitosterol and campesterol, a precursor of growth-promoting brassinosteroids.

Serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform; The B regulatory subunit may modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity). Required for the formation of the PP2A holoenzyme that positively regulates brassinosteroid signaling by dephosphorylating and activating BZR1.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform; The B regulatory subunit may modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity). Required for the formation of the PP2A holoenzyme that positively regulates brassinosteroid signaling by dephosphorylating and activating BZR1.

Serine/threonine-protein kinase BSK1; Serine/threonine kinase that acts as positive regulator of brassinosteroid (BR) signaling downstream of the receptor kinase BRI1. Mediates signal transduction from BRI1 by functioning as substrate of BRI1. Functions as a positive regulator of plant immunity. May be involved in the regulation of pattern-triggered immunity (PTI) downstream of the flagellin receptor FLS2. Possesses kinase activity in vitro. Kinase activity is required for its function in innate immunity.