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TET5 TET5 CERK1 CERK1 PHB3 PHB3 LYM2 LYM2 DBP DBP FLOT2 FLOT2 TET16 TET16 LYM3 LYM3 REM1 REM1 PDLP5 PDLP5 PDLP1 PDLP1 AtSLP1 AtSLP1 LYM1 LYM1 BAK1 BAK1 HIR2 HIR2 PDCB1 PDCB1 ACR4-2 ACR4-2 TET3 TET3 ATPD ATPD CLV1 CLV1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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TET5Tetraspanin-5; May be involved in the regulation of cell differentiation. Belongs to the tetraspanin (TM4SF) family. (281 aa)
CERK1Chitin elicitor receptor kinase 1; Lysin motif (LysM) receptor kinase that functions as a cell surface receptor in chitin elicitor (chitooligosaccharides) signaling leading to innate immunity toward both biotic and abiotic stresses (e.g. tolerance to salinity, heavy-metal stresses, and Botrytis cinerea infection). Recognizes microbe-derived N-acetylglucosamine (NAG)- containing ligands. Involved in the resistance to pathogenic fungi Alternaria brassicicola and Erysiphe cichoracearum, probably by sensing microbe-associated molecular patterns (MAMP) and pathogen-associated molecular patt [...] (617 aa)
PHB3Prohibitin-3, mitochondrial; Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins (By similarity). Necessary for mitochondrial and cell metabolism and biogenesis. Required to regulate the ethylene-mediated signaling; involved in growth maintenance in the presence of ethylene. Functions in nitric oxide (NO)-mediated responses and in hydrogen peroxide- induced NO accumulation. (277 aa)
LYM2LysM domain-containing GPI-anchored protein 2; Chitin elicitor-binding protein involved in the perception of chitin oligosaccharide elicitor. (350 aa)
DBPRemorin; Exhibits a non sequence-specific DNA-binding activity. (190 aa)
FLOT2Flotillin-like protein 2; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. (463 aa)
TET16Tetraspanin-16; May be involved in the regulation of cell differentiation. Belongs to the tetraspanin (TM4SF) family. (248 aa)
LYM3LysM domain-containing GPI-anchored protein 3; Required as a cell surface receptor for peptidoglycan (PGN) elicitor signaling leading to innate immunity. Plays an essential role in detecting PGNs and restricting bacterial growth (of Pseudomonas syringae pv. tomato DC3000 for example). (423 aa)
REM1B3 domain-containing protein REM1; May play a role in flower development. (517 aa)
PDLP5Plasmodesmata-located protein 5; Modulates cell-to-cell trafficking. Has a positive role in innate immunity. Required for systemic acquired resistance (SAR) which is mediated by the signaling molecules azelaic acid (AzA), glycerol-3- phosphate (G3P), and salicylic acid (SA). Negative regulator of plasmodesmata permeability triggered by SA during immune responses, through regulation of callose deposition. Delays the trafficking of Tobacco Mosaic Virus (TMV) movement protein (MP). Required for symplastic signal transport. (299 aa)
PDLP1Plasmodesmata-located protein 1; Modulates cell-to-cell trafficking. Required for systemic acquired resistance (SAR) which is mediated by the signaling molecules azelaic acid (AzA), glycerol-3-phosphate (G3P), and salicylic acid (SA). Required for the proper localization and stability of AZI1 which is involved in SAR. Mediates callose deposition during downy mildew fungal infection around haustoria. Haustoria are unicellular protrusions from hyphae and function as the site of molecular exchange of nutrients and effectors between host and pathogen. (303 aa)
AtSLP1SPFH/Band 7/PHB domain-containing membrane-associated protein family. (411 aa)
LYM1LysM domain-containing GPI-anchored protein 1; Required as a cell surface receptor for peptidoglycan (PGN) elicitor signaling leading to innate immunity. Plays an essential role in detecting PGNs and restricting bacterial growth (of Pseudomonas syringae pv. tomato DC3000 for example). (416 aa)
BAK1BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1; Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Controls the expression of genes associated with innate immunity in the absence of pathogens or elicitors. Involved in brassinosteroid (BR) signal transduction. Phosphorylates BRI1. May be involved in changing the equilibrium between plasma membrane-located BRI1 homodimers and endocytosed BRI1- BAK1 heterodimers. Interaction with MSBP1 stimulates the endocytosis of BAK1 and suppresses brassinosteroid signaling. Acts in pathogen- associ [...] (615 aa)
HIR2Hypersensitive-induced response protein 2. (286 aa)
PDCB1PLASMODESMATA CALLOSE-BINDING PROTEIN 1; Able to bind (1->3)-beta-D-glucans (laminarin). Probably involved in cell-to-cell trafficking regulation. (201 aa)
ACR4-2Serine/threonine-protein kinase-like protein ACR4; Controls formative cell division in meristems, including root tips and lateral root initiation zones of the pericycle, in response to CLE40 signal. Acts with CLE40p peptide as a ligand-receptor pair in a signal transduction pathway, coordinating movement of the root tip and organization of cell divisions in the root meristem. Required during embryogenesis and development, probably for the differentiation of protoderm and epidermal cells. Involved in the regulation of cellular organization during the development of sepal margins and ovu [...] (895 aa)
TET3Tetraspanin-3; May be involved in the regulation of cell differentiation. Belongs to the tetraspanin (TM4SF) family. (285 aa)
ATPDATP synthase subunit delta, chloroplastic; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Potential). Essential for photosynthesis, probably by facilitating electron transport in both [...] (234 aa)
CLV1Receptor protein kinase CLAVATA1; Involved in the detection of CLV3 and CLV3-like (CLE) peptides, that act as extracellular signals regulating meristem maintenance. Acts with CLV3p as a ligand-receptor pair in a signal transduction pathway coordinating growth between adjacent meristematic regions and controlling the balance between meristem cell proliferation and differentiation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (980 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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