STRINGSTRING
MitHPPK/DHPS MitHPPK/DHPS ISPG ISPG CTIMC CTIMC CytHPPK/DHPS CytHPPK/DHPS DHAD DHAD SIR SIR TIM TIM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MitHPPK/DHPSFolate synthesis bifunctional protein, mitochondrial; Catalyzes the first two consecutive steps of tetrahydrofolate biosynthesis; In the N-terminal section; belongs to the HPPK family. (554 aa)
ISPG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), chloroplastic; Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that converts 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Is essential for chloroplast development and required for the salicylic acid (SA)-mediated disease resistance to biotrophic pathogens. (741 aa)
CTIMCTriosephosphate isomerase, cytosolic; Belongs to the triosephosphate isomerase family. (254 aa)
CytHPPK/DHPS6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; Catalyzes the first two consecutive steps of tetrahydrofolate biosynthesis. Plays a role in seed stress response and survival. In the C-terminal section; belongs to the DHPS family. (484 aa)
DHADDihydroxy-acid dehydratase, chloroplastic; Catalyzes the dehydration of 2,3-dihydroxy-3-isovalerate or 2,3-dihydroxy-3-methylvalerate to the 2-oxo acids 3-methyl-2- oxobutanoate (3MOB) or 3-methyl-2-oxopentanoate (3MOP). (608 aa)
SIRAssimilatory sulfite reductase (ferredoxin), chloroplastic; Essential protein with sulfite reductase activity required in assimilatory sulfate reduction pathway during both primary and secondary metabolism and thus involved in development and growth. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (642 aa)
TIMTriosephosphate isomerase, chloroplastic; Belongs to the triosephosphate isomerase family. (315 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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