STRINGSTRING
F2P9.12 F2P9.12 rbcL rbcL WRKY22 WRKY22 SAUR36 SAUR36 CLH1 CLH1 CYP76C2 CYP76C2 YLS3 YLS3 GLX1 GLX1 F12L6.16 F12L6.16 GAPC1 GAPC1 ASP3 ASP3 GB1 GB1 ABI1 ABI1 SSL11 SSL11 SSL12 SSL12 BIP2 BIP2 ERD15 ERD15 SKP1A SKP1A GAPCP2 GAPCP2 T6D22.20 T6D22.20 RCCR RCCR YUC6 YUC6 F1N21.10 F1N21.10 BZIP60 BZIP60 SSL5 SSL5 EIF2A EIF2A SAG12 SAG12 LRR1 LRR1 EDR1 EDR1 GAPC2 GAPC2 PAO PAO BIP1 BIP1 PUB44 PUB44 WRKY70 WRKY70 BGLU16 BGLU16 CLH2 CLH2 GAPCP1 GAPCP1 BZIP28 BZIP28 PAT PAT MAX2 MAX2 SSL2 SSL2 DJ1E DJ1E
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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F2P9.12Calcium-dependent phosphotriesterase superfamily protein. (325 aa)
rbcLRibulose bisphosphate carboxylase large chain; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. Belongs to the RuBisCO large chain family. Type I subfamily. (479 aa)
WRKY22WRKY transcription factor 22; Transcription factor involved in the expression of defense genes in innate immune response of plants. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor- responsive cis-acting element. Activates WRKY 29, SIRK and its own promoters; Belongs to the WRKY group II-e family. (298 aa)
SAUR36Auxin-responsive protein SAUR36; Acts a positive regulator of leaf senescence and may mediate auxin-induced leaf senescence. Plays a role in the regulation of seed germination by gibberellins and abscisic acid (ABA). Plays a role in the regulation of light-dependent hypocotyl elongation ; Belongs to the ARG7 family. (162 aa)
CLH1Chlorophyllase-1; Catalyzes the hydrolysis of ester bond in chlorophyll to yield chlorophyllide and phytol. Shows a preferential activity toward chlorophyll a; Belongs to the AB hydrolase superfamily. Lipase family. (324 aa)
CYP76C2Cytochrome P450 76C2; Belongs to the cytochrome P450 family. (512 aa)
YLS3Protein YLS3. (205 aa)
GLX1Lactoylglutathione lyase GLX1; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (283 aa)
F12L6.16At2g39500/F12L6.16. (55 aa)
GAPC1Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic; Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3- phospho-D-glyceroyl phosphate. Essential for the maintenance of cellular ATP levels and carbohydrate metabolism. Required for full fertility. Involved in response to oxidative stress by mediating plant responses to abscisic acid (ABA) and water deficits through the activation of PLDDELTA and production of phosphatidic acid (PA), a multifunctional stress signaling lipid in plants. Associates with FBA6 to [...] (338 aa)
ASP3Aspartate aminotransferase 3, chloroplastic; Amino acid aminotransferase important for the metabolism of amino acids and Krebs-cycle related organic acids. No activity with D- Asp or D-Ala as amino donors. In plants, it is involved in nitrogen metabolism and in aspects of carbon and energy metabolism. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
GB1Guanine nucleotide-binding protein subunit beta; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Together with GCR1 and GPA1, acts as a negative regulator of ABA during seed germination and early seedling development. The heterotrimeric G-protein controls defense responses to necrotrophic and vascular fungi probably by modulating cell wall-related genes expression (e. [...] (377 aa)
ABI1Protein phosphatase 2C 56; Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, osmotic water permeability of the plasma membrane (Pos), drought-induced resistance and rhizogenesis, response to glucose, high light stress, seed germination and inhibition of vegetative growth. During the stomatal closure regulation, modulates the inward calcium-channel permeability as well as the actin reorganization in guard cells in response to ABA. Involved in the resistance to the bacterial pathogen Pseudomonas syrin [...] (434 aa)
SSL11Protein STRICTOSIDINE SYNTHASE-LIKE 11; Catalyzes the stereospecific condensation of tryptamine with secologanin to form strictosidine, the key intermediate of indole alkaloid biosynthesis. (329 aa)
SSL12Protein STRICTOSIDINE SYNTHASE-LIKE 12; Catalyzes the stereospecific condensation of tryptamine with secologanin to form strictosidine, the key intermediate of indole alkaloid biosynthesis. (335 aa)
BIP2Heat shock 70 kDa protein BIP2; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions (Probable). Involved in polar nuclei fusion during female gametophyte development and is essential for the regulation of endosperm nuclei proliferation. Involved in sperm nuclear fusion with central cell polar nuclei at fertilization, which is critical for normal endosperm nuclear proliferation. Req [...] (668 aa)
ERD15Protein EARLY RESPONSIVE TO DEHYDRATION 15; Central component of stress responses that interacts with poly(A)-binding proteins. Negative regulator of abscisic acid (ABA) responses, including resistance to drought and freezing as well as stomatal closure regulation. Mediates resistance to the bacterial necrotroph pathogen Erwinia carotovora subsp. carotovora and promotes the induction of marker genes for systemic acquired resistance (SAR). (163 aa)
SKP1ASKP1-like protein 1A; Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1. SCF(UFO) is required for vegetative and floral organ development as well as for male gametogenesis. SCF(TIR1) is involved in auxin signaling pathway. SCF(COI1) regulates responses to jasmonates. SCF(EID1) and SCF(AFR) are implicate [...] (160 aa)
GAPCP2Glyceraldehyde-3-phosphate dehydrogenase GAPCP2, chloroplastic; Involved in plastidial glycolytic pathway and plays a specific role in glycolytic energy production in non-green plastids and chloroplasts. Essential for breakdown of starch to form sucrose for export to non-photosynthetic tissues, and to generate primary metabolites for anabolic pathways such as fatty acid and amino acid synthesis. Plays an important role in plant development by providing substrates for the phosphorylated pathway of serine biosynthesis in roots. Plays a crucial role in pollen development. Functionally red [...] (420 aa)
T6D22.20Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (185 aa)
RCCRRed chlorophyll catabolite reductase, chloroplastic; Catalyzes the key reaction of chlorophyll catabolism, porphyrin macrocycle cleavage of pheophorbide a (pheide a) to a primary fluorescent catabolite (pFCC). Works in a two-step reaction with pheophorbide a oxygenase (PaO) by reducing the C20/C1 double bond of the intermediate, RCC. Belongs to the chlorophyll catabolic enzymes (CCEs). (319 aa)
YUC6Indole-3-pyruvate monooxygenase YUCCA6; Involved in auxin biosynthesis via the indole-3-pyruvic acid (IPA) pathway. Also able to convert in vitro phenyl pyruvate (PPA) to phenyl acetic acid (PAA). Required for the formation of floral organs and vascular tissues. Belongs to the set of redundant YUCCA genes probably responsible for auxin biosynthesis in shoots. (417 aa)
F1N21.10Probable lactoylglutathione lyase, chloroplastic; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (350 aa)
BZIP60bZIP transcription factor 60; Transcription factor involved in the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Plays a role in plant immunity and abiotic stress responses. (295 aa)
SSL5Protein STRICTOSIDINE SYNTHASE-LIKE 5. (371 aa)
EIF2AEukaryotic translation initiation factor 2 subunit alpha; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre- initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF- 2 must exchange with GTP by way of a reaction cataly [...] (344 aa)
SAG12Senescence-specific cysteine protease SAG12; Cysteine protease that may have a developmental senescence specific cell death function during apoptosis, heavy metal detoxification, and hypersensitive response. (346 aa)
LRR1Leucine-rich repeat protein 1; Involved in plant defense response. (218 aa)
EDR1Serine/threonine-protein kinase EDR1; MAPKKK serine/threonine-protein kinase involved in the regulation of a MAP kinase cascade (probably including MPK3 and MPK6) that negatively regulates salicylic acid- (SA-) dependent defense responses, abscisic acid (ABA) signaling, and ethylene-induced senescence. Modulates also stress response (e.g. drought) signaling and cell death, in an ORE9-dependent manner. Functions at a point of cross talk between ethylene, ABA and SA signaling that impinges on senescence and cell death. On the other hand, it confers sensitivity to various pathogens such a [...] (933 aa)
GAPC2Glyceraldehyde-3-phosphate dehydrogenase GAPC2, cytosolic; Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3- phospho-D-glyceroyl phosphate. Essential for the maintenance of cellular ATP levels and carbohydrate metabolism (By similarity). Binds DNA in vitro. (338 aa)
PAOPheophorbide a oxygenase, chloroplastic; Catalyzes the key reaction of chlorophyll catabolism, porphyrin macrocycle cleavage of pheophorbide a (pheide a) to a primary fluorescent catabolite (pFCC). Works in a two-step reaction with red chlorophyll catabolite reductase (RCCR). Creates the intermediate RCC through the opening of the porphyrin macrocycle by the introduction of one atom of molecular oxygen at the alpha-methine bridge. Seems to be specific for pheide a. Belongs to the chlorophyll catabolic enzymes (CCEs). (537 aa)
BIP1Heat shock 70 kDa protein BIP1; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions (Probable). Involved in polar nuclei fusion during female gametophyte development and is essential for the regulation of endosperm nuclei proliferation. Involved in sperm nuclear fusion with central cell polar nuclei at fertilization, which is critical for normal endosperm nuclear proliferation. Req [...] (669 aa)
PUB44U-box domain-containing protein 44; Functions as an E3 ubiquitin-protein ligase. Prevents premature senescence probably by targeting proteins involved in this process for degradation. Promotes the degradation of AAO3 and thus represses abscisic acid (ABA) biosynthesis. (801 aa)
WRKY70Probable WRKY transcription factor 70; Transcription factor involved in senescence, biotic and abiotic stress responses by modulating various phytohormones signaling pathways. Interacts specifically with the W box (5'- (T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Binds to the 5'-[CT]GACTTTT-3' motif in promoters of target genes to induce their expression. Plays an important but not indispensable role in jasmonate and salicylic acid signaling. Regulates positively the salicylic acid (SA)-mediated signal pathway, but negatively the jasmo [...] (294 aa)
BGLU16Beta-glucosidase 16. (514 aa)
CLH2Chlorophyllase-2, chloroplastic; Catalyzes the hydrolysis of ester bond in chlorophyll to yield chlorophyllide and phytol. (318 aa)
GAPCP1Glyceraldehyde-3-phosphate dehydrogenase GAPCP1, chloroplastic; Involved in plastidial glycolytic pathway and plays a specific role in glycolytic energy production in non-green plastids and chloroplasts. Essential for breakdown of starch to form sucrose for export to non-photosynthetic tissues, and to generate primary metabolites for anabolic pathways such as fatty acid and amino acid synthesis. Plays an important role in plant development by providing substrates for the phosphorylated pathway of serine biosynthesis in roots. Plays a crucial role in pollen development. Functionally red [...] (422 aa)
BZIP28bZIP transcription factor 28; Transcriptional activator involved in ER stress responses. Functions as a stress sensor and transducer in ER stress signaling pathway. After proteolysis by SBT6.1 (S1P) and S2P, the N-terminal bZIP component is translocated to the nucleus, where it activates the expression and production of ER chaperones. Following ER stress, activates proteins involved in brassinosteroid (BR) signaling, which is required for stress acclimation and growth. (675 aa)
PATBifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase; Prokaryotic-type aspartate aminotransferase. Has also a prenate transaminase activity. Involved in the aromatic amino acids biosynthesis pathway via the arogenate route. Required for the transamination of prephenate into arogenate. Required for early development of the embryo. (475 aa)
MAX2F-box protein MAX2; Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the senescence. Is necessary for responses to strigolactones and karrikins. Contributes to the selective repression of axillary shoots and moderates the branching by regulating negatively the auxin transport in primary stems, in an AXR1-independent manner. Required for the progression of leaf senescence mediated by methyl jasmonate. Required at each node to suppress axillary bud growth. (693 aa)
SSL2Protein STRICTOSIDINE SYNTHASE-LIKE 2. (376 aa)
DJ1EDJ-1 protein homolog E; May be involved in oxidative stress response; Belongs to the peptidase C56 family. (398 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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