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RABF1 RABF1 BIG5 BIG5 CURT1A CURT1A SNC1 SNC1 SEC13B SEC13B VIPP1 VIPP1 FTSZ2-1 FTSZ2-1 CAM1 CAM1 CAM2 CAM2 GPA1 GPA1 CML10 CML10 AP3 AP3 DRP1A DRP1A AP2 AP2 CAM7 CAM7 RABB1C RABB1C CAM6 CAM6 CHC2 CHC2 CHC1 CHC1 FZL FZL FTSZ1 FTSZ1 ARC5 ARC5 OBGL OBGL REP REP Dl4805W Dl4805W CYCL1-1 CYCL1-1 DRP3A DRP3A SCO2 SCO2 CP1 CP1 PDV1 PDV1 PGK1 PGK1 FTSZ2-2 FTSZ2-2 THF1 THF1 PDV2 PDV2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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RABF1Ras-related protein RABF1; Endosomal protein probably involved in endocytosis. Probably not involved in vacuolar trafficking. (202 aa)
BIG5Brefeldin A-inhibited guanine nucleotide-exchange protein 5; Activates the ARF proteins by exchanging bound GDP for free GTP. Plays a role in vesicular protein sorting. Acts as the major regulator of early endosomal vesicle trafficking but is also involved in the endocytosis process. Target of hopM1, a conserved Pseudomonas syringae virulence protein that directs the protein to its own proteasome-mediated degradation. Plays a broad role in PAMP-triggered immunity (PTI), effector-triggered immunity (ETI), and salicylic acid (SA)-regulated immunity. (1739 aa)
CURT1AProtein CURVATURE THYLAKOID 1A, chloroplastic; Determines thylakoid architecture by inducing membrane curvature. (164 aa)
SNC1Protein SUPPRESSOR OF npr1-1, CONSTITUTIVE 1; Disease resistance protein of the TIR-NB-LRR-type. Part of the RPP5 locus that contains a cluster of several paralogous disease resistance (R) genes. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. Probably acts as a NAD(+) hydrolase (NADase): in response to activation, catalyzes cleavage of NAD(+) into ADP-D- ribose (ADPR) an [...] (1437 aa)
SEC13BProtein transport protein SEC13 homolog B; Required for protein transport from the endoplasmic reticulum to the Golgi apparatus. (302 aa)
VIPP1Membrane-associated protein VIPP1, chloroplastic; Required for plastid vesicle formation and thylakoid membrane biogenesis, but not for functional assembly of thylakoid protein complexes; Belongs to the PspA/IM30 family. (330 aa)
FTSZ2-1Cell division protein FtsZ homolog 2-1, chloroplastic; Exhibits GTPase activity. Component of the plastid division machinery that forms a contractile ring at the division site. Required for plastid division in a dose-dependent manner. Belongs to the FtsZ family. (478 aa)
CAM1Calmodulin-1; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
CAM2Calmodulin-2; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
GPA1Guanine nucleotide-binding protein alpha-1 subunit; Exhibits a fast rate of basal nucleotide exchange. Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Together with GCR1, may regulate the cell cycle via a signaling cascade that uses phosphatidylinositol-specific phospholipase C (PI-PLC) as an effector and inositol 1,4,5-trisphosphate (IP(3)) as a second messenger. Promotes abscisic acid (ABA) responses in guard cells. But, together with GCR1 and GB1, acts as a negative regulator of ABA during seed ge [...] (383 aa)
CML10Calmodulin-like protein 10; Potential calcium sensor. (191 aa)
AP3Floral homeotic protein APETALA 3; Probable transcription factor involved in the genetic control of flower development. Is required for normal development of petals and stamens in the wild-type flower. Forms a heterodimer with PISTILLATA that is required for autoregulation of both AP3 and PI genes. AP3/PI heterodimer interacts with APETALA1 or SEPALLATA3 to form a ternary complex that could be responsible for the regulation of the genes involved in the flower development. AP3/PI heterodimer activates the expression of NAP. AP3/PI prevents GATA22/GNL and GATA21/GNC expression. (232 aa)
DRP1ADynamin-related protein 1A; Microtubule-associated force-producing protein that is targeted to the forming cell plate during cytokinesis. Plays also a major role in plasma membrane maintenance and cell wall integrity with implications in vesicular trafficking, polar cell expansion, vascular formation, and other aspects of plant growth and development. Has a GTPase activity. (610 aa)
AP2Floral homeotic protein APETALA 2; Probable transcriptional activator that promotes early floral meristem identity. Is required subsequently for the transition of an inflorescence meristem into a floral meristem. Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower, by spatially controlling the expression domains of multiple floral organ identity genes. Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in association with other repressors like LEUNIG and [...] (432 aa)
CAM7Calmodulin-7; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Activates MPK8 in vitro. (149 aa)
RABB1CRas-related protein RABB1c; Intracellular vesicle trafficking and protein transport. Belongs to the small GTPase superfamily. Rab family. (211 aa)
CAM6Calmodulin-6; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
CHC2Clathrin heavy chain 2; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). Mediates endocytosis and is required for a correct polar distribution of PIN auxin transporters. (1703 aa)
CHC1Clathrin heavy chain 1; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). Mediates endocytosis and is required for a correct polar distribution of PIN auxin transporters. Belongs to the clathrin heavy chain family. (1705 aa)
FZLProbable transmembrane GTPase FZO-like, chloroplastic; Probable membrane-remodeling GTPase that plays a unique role in the in the determination of thylakoid and chloroplast morphology and regulates organization of the thylakoid network. Not involved in the determination of mitochondrial morphology or ultrastructure. Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. Mitofusin subfamily. (912 aa)
FTSZ1Cell division protein FtsZ homolog 1, chloroplastic; Exhibits GTPase activity. Component of the plastid division machinery that forms a contractile ring at the division site. Required for plastid division in a dose-dependent manner. Involved in blue light-induced chloroplast movements. May regulate thylakoid development. Belongs to the FtsZ family. (433 aa)
ARC5Dynamin-like protein ARC5; Probable GTPase component of both plastid and peroxisme division machinery. Required for the last steps of plastid division specifically in mesophyll-cell, when the narrow isthmus breaks, facilitating the separation of the daughter plastids. Necessary for peroxisome activities. Seems to influence stromule (stroma-filled tubular extensions of the plastid envelope membrane) length and frequency. Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (777 aa)
OBGLGTP-binding protein OBGC, chloroplastic; GTP-binding protein involved in membrane biogenesis and protein synthesis in chloroplast. Functions in the biogenesis of thylakoid membrane and plastid ribosome during chloroplast development. May be involved in the vesicular traffic between the chloroplast inner envelope membrane and thylakoids. Possesses GTPase activity in vitro. (681 aa)
REPRab escort protein 1; Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component composed of the alpha subunit RGTA and the beta subunit RGTB (Probable). Preferentially binds the GDP-bound form of Rab and stimulates geranylgeranylation of various Rab GTPases in vitro. (563 aa)
Dl4805WDynamin. (294 aa)
CYCL1-1Cyclin-L1-1; Cognate cyclin for CDKG1. Required for synapsis and male meiosis, and for the proper splicing of specific resistance (R) genes. Involved in regulation of DNA methylation and transcriptional silencing. (416 aa)
DRP3ADynamin-related protein 3A; Involved in the control of mitochondrial and peroxisomal division and morphology. In association with PEX11C, PEX11D, PEX11E and FIS1B, is involved in cell cycle-associated constitutive self- replication of preexisting peroxisomes. Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (808 aa)
SCO2Protein disulfide-isomerase SCO2; Protein disulfide-isomerase involved in chloroplast development in cotyledons. Involved in the process of vesicle-derived thylakoid formation, probably at the level of the integration and folding of LHCB proteins at the initial location of integration. Acts only in germinating seeds after dormancy, during the transition from heterotrophic to autotrophic growth. (187 aa)
CP1Calcium-binding protein CP1; Binds calcium in vitro. (160 aa)
PDV1Plastid division protein PDV1; Component of the plastid division machinery. Required to mediate the recruitment of ARC5 at the midplastid constriction site in the cytoplasm. (272 aa)
PGK1Phosphoglycerate kinase 1, chloroplastic; Belongs to the phosphoglycerate kinase family. (481 aa)
FTSZ2-2Cell division protein FtsZ homolog 2-2, chloroplastic; Exhibits GTPase activity (By similarity). Component of the plastid division machinery that forms a contractile ring at the division site. (473 aa)
THF1Protein THYLAKOID FORMATION 1, chloroplastic; Involved in a dynamic process of vesicle-mediated thylakoid membrane biogenesis. Required for the normal organization of vesicles into mature thylakoid stacks and ultimately for leaf development. Also involved in a sugar-signaling mechanism in roots by mediating signaling between the plasma membrane and the plastid. Probably acts downstream of the plasma membrane-delimited heterotrimeric G-protein GPA1 in a D- glucose signaling pathway; Belongs to the THF1 family. (300 aa)
PDV2Plastid division protein PDV2; Component of the plastid division machinery. Required to mediate the recruitment of ARC5 at the midplastid constriction site in the cytoplasm. Relays plastid division site position between stroma and outer surface via interactions with the cytoplasmic ARC5 and the inner membrane ARC6 that recruits stromal FtsZ ring. (307 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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