STRINGSTRING
PRB1 PRB1 PAL4 PAL4 CSY3 CSY3 RAR1 RAR1 GBSS1 GBSS1 PSA3 PSA3 CSY5 CSY5 CSY1 CSY1 CSY2 CSY2 F2J10.6 F2J10.6 FMO1 FMO1 Q9LJM5_ARATH Q9LJM5_ARATH CDC73 CDC73 T10D10.18 T10D10.18 RPN7 RPN7 F13O11.3 F13O11.3 T4C12_30 T4C12_30 K7J8.9 K7J8.9 AGT1 AGT1 PR1 PR1 PR-1-LIKE PR-1-LIKE FTSH1 FTSH1 MPK4 MPK4 CRT2 CRT2 PAL3 PAL3 PAL2 PAL2 PAL1 PAL1 PR1-2 PR1-2 PR5 PR5 CSY4 CSY4 RCA RCA T16L1.220 T16L1.220 T16L1.210 T16L1.210 C7A10.770 C7A10.770 CRT3 CRT3 CRT1 CRT1 F4K727_ARATH F4K727_ARATH F6N18.16 F6N18.16
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRB1Pathogenesis-related protein 1; Probably involved in the defense reaction of plants against pathogens. (161 aa)
PAL4Phenylalanine ammonia-lyase 4; This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton; Belongs to the PAL/histidase family. (707 aa)
CSY3Citrate synthase 3, peroxisomal; Peroxisomal citrate synthase required for the fatty acid respiration in seedlings, citrate being exported from peroxisomes into mitochondria during respiration of triacylglycerol (TAG). Indeed, complete respiration requires the transfer of carbon in the form of citrate from the peroxisome to the mitochondria. (509 aa)
RAR1Cysteine and histidine-rich domain-containing protein RAR1; Required specifically for plant innate immunity. Is essential for resistance conferred by multiple R genes recognizing different bacterial and oomycete pathogen isolates like avirulent P.syringae or H.parasitica (downy mildew). Contributes additively with SGT1B to RPP5- dependent resistance. Functions as positive regulator of RPS5 accumulation by assisting its stabilization. May function as co- chaperone of HSP90-2 to positively regulate the steady-state accumulation of RPM1 and protect it from SGT1-mediated degradation. Acts [...] (226 aa)
GBSS1Granule-bound starch synthase 1, chloroplastic/amyloplastic; Required for the synthesis of amylose. Destroyed as it is released from the starch granules during the night. The circadian expression is controlled by CCA1 and LHY transcription factors. (610 aa)
PSA3Photosystem I assembly factor PSA3, chloroplastic; Nuclear genome-encoded factor required for the accumulation of photosystem I (PSI). Functions as PSI biogenesis factor. Cooperates with PYG7 to promote the stable assembly of PSI in the thylakoid membrane. May target primarily the PsaC subunit. Does not seem to be required for the expression of chloroplast genes encoding PSI subunits. (277 aa)
CSY5Citrate synthase 5, mitochondrial; Belongs to the citrate synthase family. (464 aa)
CSY1Citrate synthase 1, peroxisomal; Belongs to the citrate synthase family. (480 aa)
CSY2Citrate synthase 2, peroxisomal; Peroxisomal citrate synthase required for the fatty acid respiration in seedlings, citrate being exported from peroxisomes into mitochondria during respiration of triacylglycerol (TAG). Indeed, complete respiration requires the transfer of carbon in the form of citrate from the peroxisome to the mitochondria. (514 aa)
F2J10.6F2J10.6 protein; Belongs to the CRISP family. (161 aa)
FMO1Probable flavin-containing monooxygenase 1; Required for the establishment of systemic acquired resistance (SAR). Not involved in local defense mechanisms. Confers a salicylic acid-dependent (SA) resistance to virulent pathogens such as P.syringae pv tomato and H.parasitica. (530 aa)
Q9LJM5_ARATHPathogenesis-related protein-like; Belongs to the CRISP family. (161 aa)
CDC73Protein CDC73 homolog; Component of the PAF1 complex (PAF1C) which is involved in histone modifications such as methylation on histone H3 'Lys-4' (H3K4me3). Involved in regulation of flowering time. Required for the expression of the flowering repressors FLC and MADS- box genes of the MAF family. Required for histone H3 trimethylation on 'Lys-4' (H3K4me3) at the FLC locus. Prevents trimethylation on 'Lys-27' (H3K27me3) at the same locus. (415 aa)
T10D10.18Putative SRF-type transcription factor; 73282-73956. (224 aa)
RPN726S proteasome non-ATPase regulatory subunit 6 homolog; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (387 aa)
F13O11.3Alcohol dehydrogenase-like 4; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (380 aa)
T4C12_30Alcohol dehydrogenase-like 6. (381 aa)
K7J8.9MADS-box transcription factor family protein. (334 aa)
AGT1Serine--glyoxylate aminotransferase; Photorespiratory enzyme that catalyzes transamination reactions with multiple substrates, including asparagine. Function exclusively as a catabolic enzyme in Asn metabolism. Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (401 aa)
PR1Putative pathogenesis-related protein 1, 18.9K; Belongs to the CRISP family. (166 aa)
PR-1-LIKEPathogenesis-related protein-1-like protein; Belongs to the CRISP family. (176 aa)
FTSH1ATP-dependent zinc metalloprotease FTSH 1, chloroplastic; Part of a complex that function as an ATP-dependent zinc metallopeptidase. Involved in the thylakoid formation and in the removal of damaged D1 in the photosystem II, preventing cell death under high-intensity light conditions. (716 aa)
MPK4Mitogen-activated protein kinase 4; The ANPs-MKK6-MPK4 module is involved in the regulation of plant cytokinesis during meiosis and mitosis. Essential to promote the progression of cytokinesis and for cellularization (formation of the cell plate) during male-specific meiosis. Involved in cortical microtubules organization and stabilization by regulating the phosphorylation state of microtubule-associated proteins such as MAP65- 1. Involved in root hair development process. Negative regulator of systemic acquired resistance (SAR) and salicylic acid- (SA) mediated defense response. Requi [...] (376 aa)
CRT2Calreticulin-2; Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity). (424 aa)
PAL3Phenylalanine ammonia-lyase 3; This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton. (694 aa)
PAL2Phenylalanine ammonia-lyase 2; This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton; Belongs to the PAL/histidase family. (717 aa)
PAL1Phenylalanine ammonia-lyase 1; This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton; Belongs to the PAL/histidase family. (725 aa)
PR1-2Pathogenesis-related protein 1; Partially responsible for acquired pathogen resistance. (161 aa)
PR5Pathogenesis-related protein 5; Partially responsible for acquired pathogen resistance. (239 aa)
CSY4Citrate synthase 4, mitochondrial; Belongs to the citrate synthase family. (474 aa)
RCARibulose bisphosphate carboxylase/oxygenase activase, chloroplastic; Activation of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase; EC 4.1.1.39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure. (474 aa)
T16L1.220Pathogenesis-related protein-like; Belongs to the CRISP family. (172 aa)
T16L1.210Putative pathogenesis-related protein 1, 19.3K; Belongs to the CRISP family. (163 aa)
C7A10.770MADS-box transcription factor family protein. (248 aa)
CRT3Calreticulin-3; Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Required for elongation factor Tu receptor (EFR) accumulation and for EFR, but not flagellin-sensing 2 (FLS2) signaling. (424 aa)
CRT1Calreticulin-1; Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity). (425 aa)
F4K727_ARATHTryptophan synthase. (465 aa)
F6N18.16Alcohol dehydrogenase-like 3. (394 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.