STRINGSTRING
PKP1 PKP1 IAA19 IAA19 EIN3 EIN3 M3E9.180 M3E9.180 EXPA15 EXPA15 F12L6.16 F12L6.16 GH3.1 GH3.1 PSBO1 PSBO1 GASA1 GASA1 AP2 AP2 KNAT3 KNAT3 ETR1 ETR1 IAA2 IAA2 ARF7 ARF7 ARF5 ARF5 ACO4 ACO4 AGL66 AGL66 IAA6 IAA6 IAA7 IAA7 IAA9 IAA9 IAA12 IAA12 IAA13 IAA13 IAA14 IAA14 CYCB1-2 CYCB1-2 GA3OX1 GA3OX1 GA20OX1 GA20OX1 SMT2 SMT2 SAUR15 SAUR15 HXK1 HXK1 ACO1 ACO1 ASB1 ASB1 PHT4;4 PHT4;4 RGL2 RGL2 MPA1 MPA1 IAA26 IAA26 ERF1B ERF1B GA2OX1 GA2OX1 XTH16 XTH16 PIN4 PIN4 FHY1-2 FHY1-2 PKP3 PKP3 ARF2 ARF2 Q94KE3_ARATH Q94KE3_ARATH AUX1 AUX1 DELTA-ADR DELTA-ADR GA2OX4 GA2OX4 RGL1 RGL1 BZIP8 BZIP8 F4F7.41 F4F7.41 MBK5.16 MBK5.16 ARF8 ARF8 PKP2 PKP2 MCD7.8 MCD7.8 MAH20.13 MAH20.13 RGL3 RGL3 GAI GAI GH3.6 GH3.6 Q9LU95_ARATH Q9LU95_ARATH GID1B GID1B BLH9 BLH9 F1I16_220 F1I16_220 F1I16_60 F1I16_60 EXPB3 EXPB3 SCL13 SCL13 PKP4 PKP4 CYFBP CYFBP LAX2 LAX2 BLH1 BLH1 AGO5 AGO5 F1O11.21 F1O11.21 EXPB1 EXPB1 EIL1 EIL1 RGA RGA T11I18.16 T11I18.16 GID2 GID2 SCL14 SCL14 ARF9 ARF9 AGO10 AGO10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PKP1Plastidial pyruvate kinase 1, chloroplastic; Required for plastidial pyruvate kinase activity. Involved in seed oil accumulation, embryo development and seed storage compounds mobilization upon germination. (596 aa)
IAA19Auxin-responsive protein IAA19; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin- responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. (197 aa)
EIN3Protein ETHYLENE INSENSITIVE 3; Probable transcription factor acting as a positive regulator in the ethylene response pathway. Is required for ethylene responsiveness in adult plant tissues. Binds a primary ethylene response element present in the ETHYLENE-RESPONSE-FACTOR1 promoter with consequence to activate the transcription of this gene. (628 aa)
M3E9.180Probable pyruvate kinase, cytosolic isozyme; Key regulatory enzyme of the glycolytic pathway that catalyzes the final step of glycolysis, converting ADP and phosphoenolpyruvate (PEP) to ATP and pyruvate by essentially irreversible transphosphorylation. (497 aa)
EXPA15Expansin-A15; Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found (By similarity). Belongs to the expansin family. Expansin A subfamily. (253 aa)
F12L6.16At2g39500/F12L6.16. (55 aa)
GH3.1Probable indole-3-acetic acid-amido synthetase GH3.1; Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin; Belongs to the IAA-amido conjugating enzyme family. (590 aa)
PSBO1Oxygen-evolving enhancer protein 1-1, chloroplastic; Stabilizes the manganese cluster which is the primary site of water splitting. (332 aa)
GASA1Gibberellin-regulated protein 1; Gibberellin-regulated protein that may function in hormonal controlled steps of development such as seed germination, flowering and seed maturation; Belongs to the GASA family. (98 aa)
AP2Floral homeotic protein APETALA 2; Probable transcriptional activator that promotes early floral meristem identity. Is required subsequently for the transition of an inflorescence meristem into a floral meristem. Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower, by spatially controlling the expression domains of multiple floral organ identity genes. Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in association with other repressors like LEUNIG and [...] (432 aa)
KNAT3Homeobox protein knotted-1-like 3; Belongs to the TALE/KNOX homeobox family. (431 aa)
ETR1Ethylene receptor 1; Ethylene receptor related to bacterial two-component regulators. Acts as a redundant negative regulator of ethylene signaling. In the presence of ethylene, the auto-kinase activity of ETR1 is inhibited and the non- phosphorylated kinase domain binds tightly to the corresponding domain of EIN2. (738 aa)
IAA2Auxin-responsive protein IAA2; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin- responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. (174 aa)
ARF7Auxin response factor 7; Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Act as a transcriptional activator of several tropic stimulus-induced (TSI) genes, including SAUR50. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Required for differential growth responses of aerial tissues. Involved in ethylene responses. Regulates lateral root formation through direct regulation of LBD16 and/or LB [...] (1164 aa)
ARF5Auxin response factor 5; Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Mediates embryo axis formation and vascular tissues differentiation. Functionally redundant with ARF7. May be necessary to counteract AMP1 activity. (902 aa)
ACO41-aminocyclopropane-1-carboxylate oxidase 4; Enzyme involved in the ethylene biosynthesis. May promote stem elongation by maximizing the extensibility cells, possibly by activating ethylene biosynthesis, in response to very-long-chain fatty acids (VLCFAs C20:0 to C30:0); Belongs to the iron/ascorbate-dependent oxidoreductase family. (323 aa)
AGL66Agamous-like MADS-box protein AGL66; Probable transcription factor that forms a heterodimer with the MADS-box protein AGL30 and is involved in the regulation of pollen maturation at the late stages of pollen development and pollen tube growth. (332 aa)
IAA6Auxin-responsive protein IAA6; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin- responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. (189 aa)
IAA7Auxin-responsive protein IAA7; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin- responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. (243 aa)
IAA9Auxin-responsive protein IAA9; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin- responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. (338 aa)
IAA12Auxin-responsive protein IAA12; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin- responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. (239 aa)
IAA13Auxin-responsive protein IAA13; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin- responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. (247 aa)
IAA14Auxin-responsive protein IAA14; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin- responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. (228 aa)
CYCB1-2Cyclin-B1-2; May induce mitotic cell division. (445 aa)
GA3OX1Gibberellin 3-beta-dioxygenase 1; Converts the inactive gibberellin (GA) precursors GA9 and GA20 in the bioactives gibberellins GA4 and GA1. Involved in the production of bioactive GA for vegetative growth and development. Belongs to the iron/ascorbate-dependent oxidoreductase family. GA3OX subfamily. (358 aa)
GA20OX1Gibberellin 20 oxidase 1; Key oxidase enzyme in the biosynthesis of gibberellin that catalyzes the conversion of GA12 and GA53 to GA9 and GA20 respectively, via a three-step oxidation at C-20 of the GA skeleton. GA53 is less effectively oxidized than GA12, and GA25 is also formed as a minor product. Involved in the promotion of the floral transition, fertility and silique elongation, but plays only a minor role in elongation of seedling organs. Acts redundantly with GA20OX2. Belongs to the iron/ascorbate-dependent oxidoreductase family. GA20OX subfamily. (377 aa)
SMT224-methylenesterol C-methyltransferase 2; Catalyzes the methyl transfer from S-adenosyl-methionine to the methylene group of 24-methylene lophenol to form 24-ethylidene lophenol. (361 aa)
SAUR15Auxin-responsive protein SAUR15; Functions as a positive effector of cell expansion through modulation of auxin transport. (89 aa)
HXK1Hexokinase-1; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells. Promotes roots and leaves growth. Belongs to the hexokinase family. (496 aa)
ACO1Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. Contributes to oxidative stress tolerance. May have a role in respiration. Belongs to the aconitase/IPM isomerase family. (898 aa)
ASB1Anthranilate synthase beta subunit 1, chloroplastic; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS to produce anthranilate. Plays an important regulatory role in auxin production via the tryptophan-dependent biosyntheti [...] (276 aa)
PHT4;4Ascorbate transporter, chloroplastic; Inorganic phosphate and probable anion transporter. Ascorbate transporter bridging the chloroplast envelope. Transports ascorbate from the cytosol into the chloroplast. Requires chloride ions and the presence of an electrochemical potential across the membrane for activity. Belongs to the major facilitator superfamily. Sodium/anion cotransporter (TC 2.A.1.14) family. (541 aa)
RGL2DELLA protein RGL2; Probable transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. No effect of the BOI proteins on its stability. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Upon GA application, it is degraded by the proteasome, allowing the GA signaling pathway. Acts as a major GA-response repressor of seed germination, including seed thermoinhibition. Promotes the biosynthesis of abscisic acid (ABA), especially in seed coats to maintain seed dormancy. Delays flowering and adu [...] (547 aa)
MPA1Puromycin-sensitive aminopeptidase; Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. Plays an essential role during prophase I of meiosis. Required for correct meiotic reconbination in both male and female gametophytes. (883 aa)
IAA26Auxin-responsive protein IAA26; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin- responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. (269 aa)
ERF1BEthylene-responsive transcription factor 1B; Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression during the plant development, and/or mediated by stress factors and by components of stress signal transduction pathways. Seems to be a key integrator of ethylene and jasmonate signals in the regulation of ethylene/jasmonate-dependent defenses. Can mediate resistance to necrotizing fungi (Botrytis cinerea and Plectosphaerella cucumerina) and to soil borne fungi (Fusarium oxysporum conglutinans and Fus [...] (218 aa)
GA2OX1Gibberellin 2-beta-dioxygenase 1; Catalyzes the 2-beta-hydroxylation of several biologically active gibberellins, leading to the homeostatic regulation of their endogenous level. Catabolism of gibberellins (GAs) plays a central role in plant development. Converts GA9/GA20 to GA51/GA29 and GA4/GA1 to GA34/GA8; Belongs to the iron/ascorbate-dependent oxidoreductase family. GA2OX subfamily. (329 aa)
XTH16Probable xyloglucan endotransglucosylase/hydrolase protein 16; Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues (By similarity); Belongs to the glycosyl hydrolase 16 family. XTH group 2 subfamily. (291 aa)
PIN4Auxin efflux carrier component 4; Acts as a component of the auxin efflux carrier. Plays a role in generating a sink for auxin into columella cells. Maintains the endogenous auxin gradient, which is essential for correct root patterning. Involved in EXO70A3-regulated gravitropic responses in columella cells and in root system architecture (RSA). (616 aa)
FHY1-2Protein FAR-RED ELONGATED HYPOCOTYL 1; Key regulator of far red / red (FR/R) spectrum-specific responses essential for the adaption to changing light conditions (e.g. de-etiolation), essentially by regulating PHYA shuttling from the cytoplasm to the nucleus and by directly regulating the expression of some target genes, depending on light conditions and phosphorylation status. Binds chromatin at target genes promoters, especially in FR light conditions. Can activate transcription of different genes, some being in a phytochrome A (PHYA)- dependent and other in a PHYA-independent manners [...] (202 aa)
PKP3Plastidial pyruvate kinase 3, chloroplastic; Required for plastidial pyruvate kinase activity. (571 aa)
ARF2Auxin response factor 2; Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Promotes flowering, stamen development, floral organ abscission and fruit dehiscence. Functions independently of ethylene and cytokinin response pathways. May act as a repressor of cell division and organ growth. (859 aa)
Q94KE3_ARATHPyruvate kinase; Belongs to the pyruvate kinase family. (527 aa)
AUX1Auxin transporter protein 1; Carrier protein involved in proton-driven auxin influx. Mediates the formation of auxin gradient from developing leaves (site of auxin biosynthesis) to tips by contributing to the loading of auxin in vascular tissues and facilitating acropetal (base to tip) auxin transport within inner tissues of the root apex, and basipetal (tip to base) auxin transport within outer tissues of the root apex. Unloads auxin from the mature phloem to deliver the hormone to the root meristem via the protophloem cell files. Coordinated subcellular localization of AUX1 is regula [...] (485 aa)
DELTA-ADRAP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which seems to be clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole. It also function in maintaining the identity of lytic vacuoles and in regulating the transition between storage and lytic vacuoles; Belongs to the adaptor complexes large subunit family. (869 aa)
GA2OX4Gibberellin 2-beta-dioxygenase 4; Catalyzes the 2-beta-hydroxylation of several biologically active gibberellins, leading to the homeostatic regulation of their endogenous level. Catabolism of gibberellins (GAs) plays a central role in plant development. Converts GA9/GA20 to GA51/GA29 and GA4/GA1 to GA34/GA8; Belongs to the iron/ascorbate-dependent oxidoreductase family. GA2OX subfamily. (321 aa)
RGL1DELLA protein RGL1; Probable transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. No effect of the BOI proteins on its stability. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Has overlapping but distinct roles in GA signaling compared to RGA and GAI. Regulates the floral development. May also participate in seed germination and in ovule and anther development. Its activity is probably regulated by other phytohormones such as auxin and ethylene. (511 aa)
BZIP8Basic leucine zipper 8; Belongs to the bZIP family. (138 aa)
F4F7.41Glutamine amidotransferase type 1 family protein. (222 aa)
MBK5.16Pyruvate kinase; Belongs to the pyruvate kinase family. (510 aa)
ARF8Auxin response factor 8; Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF6. Involved in fruit initiation. Acts as an inhibitor to stop further carpel development in the absence of fertilizati [...] (811 aa)
PKP2Plastidial pyruvate kinase 2; Required for plastidial pyruvate kinase activity. Involved in seed oil accumulation, embryo development and seed storage compounds mobilization upon germination. (579 aa)
MCD7.8Pyruvate kinase; Belongs to the pyruvate kinase family. (498 aa)
MAH20.13Pyruvate kinase; Belongs to the pyruvate kinase family. (510 aa)
RGL3DELLA protein RGL3; Probable transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. No effect of the BOI proteins on its stability. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Its activity may be regulated by phytohormones such as auxin and ethylene (By similarity); Belongs to the GRAS family. DELLA subfamily. (523 aa)
GAIDELLA protein GAI; Transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. Transcription coactivator of the zinc finger transcription factors GAF1/IDD2 and ENY/IDD1 in regulation of gibberellin homeostasis and signaling. No effect of the BOI proteins on its stability. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Positively regulates XERICO expression. In contrast to RGA, it is less sensitive to GA. Its activity is probably regulated by other phytohormones such as auxin and ethylene [...] (533 aa)
GH3.6Indole-3-acetic acid-amido synthetase GH3.6; Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin. Strongly reactive with Glu, Gln, Trp, Asp, Ala, Leu, Phe, Gly, Tyr, Met, Ile and Val. Little or no product formation with His, Ser, Thr, Arg, Lys, or Cys. Also active on pyruvic and butyric acid analogs of IAA, PAA and the synthetic auxin naphthaleneacetic acid (NAA). The two chlorinated synthetic auxin herbicides 2,4-D and 3,6-dichloro-o-anisic acid (dicamba) cannot be used as substrates [...] (612 aa)
Q9LU95_ARATHPyruvate kinase; Belongs to the pyruvate kinase family. (497 aa)
GID1BGibberellin receptor GID1B; Functions as soluble gibberellin (GA) receptor. GA is an essential hormone that regulates growth and development in plants. Binds with high affinity the biologically active gibberellin GA4, but has no affinity for the biologically inactive GAs. In response to GA, interacts with specific DELLA proteins, known as repressors of GA- induced growth, and targets them for degradation via proteasome. Seems to be required for GA signaling that controls root growth, seed germination and flower development. May function as a dominant GA receptor at low GA concentration [...] (358 aa)
BLH9BEL1-like homeodomain protein 9; Transcription factor that is involved in the preservation of the spiral phyllotactic arrangement leading to a regular pattern of organ initiation. Required for maintenance of stem cell fate in the shoot apical meristem, and is essential for specifying floral primordia and establishing early internode patterning events during inflorescence development. Acts as transcription repressor of AG expression in floral and inflorescence meristems. Is also responsive of the nuclear import of SHOOT MERISTEMLESS (STM). In the fruit, plays a central role in patternin [...] (575 aa)
F1I16_220Pyruvate kinase; Belongs to the pyruvate kinase family. (492 aa)
F1I16_60Pyruvate kinase; Belongs to the pyruvate kinase family. (510 aa)
EXPB3Expansin-B3; May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found (By similarity). (264 aa)
SCL13Scarecrow-like protein 13; Probable transcription factor that acts as a positive regulator of continuous red light signals downstream of phytochrome B (phyB). Required for the regulation of hypocotyl elongation during de- etiolation. May be required to modulate phytochrome A (phyA) signal transduction in a phyB-independent way. (529 aa)
PKP4Plastidial pyruvate kinase 4, chloroplastic. (710 aa)
CYFBPFructose-1,6-bisphosphatase, cytosolic; Catalyzes the first irreversible reaction from fructose-1,6- bisphosphate to fructose-6-phosphate and inorganic phosphate and plays an important regulatory role in sucrose biosynthesis and metabolism (Probable). Its activity is essential to regulate starch levels. Functions in fructose-mediated signaling independently of its catalytic activity in sugar metabolism. May act downstream of ABA2/GIN1, which is involved in abscisic acid (ABA) synthesis to regulate autotrophic transition and modulate early seedling establishment after seed germination. [...] (341 aa)
LAX2Auxin transporter-like protein 2; Carrier protein involved in proton-driven auxin influx. Mediates the formation of auxin gradient from developing leaves (site of auxin biosynthesis) to tips by contributing to the loading of auxin in vascular tissues and facilitating acropetal (base to tip) auxin transport within inner tissues of the root apex, and basipetal (tip to base) auxin transport within outer tissues of the root apex (By similarity); Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.1) subfamily. (483 aa)
BLH1BEL1-like homeodomain protein 1; Belongs to the TALE/BELL homeobox family. (680 aa)
AGO5Protein argonaute 5; Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Associates with siRNAs of various sizes, from 21-24 nucleotide in length and preferentially recruits small RNAs with a 5' terminal cytosine. Probably involved in antiviral RNA silencing. Associates with siRNAs derived from cuc [...] (997 aa)
F1O11.21Pyruvate kinase; Belongs to the pyruvate kinase family. (527 aa)
EXPB1Expansin-B1; May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found (By similarity). Belongs to the expansin family. Expansin B subfamily. (271 aa)
EIL1ETHYLENE INSENSITIVE 3-like 1 protein; Probable transcription factor acting as a positive regulator in the ethylene response pathway. Could bind the primary ethylene response element present in the ETHYLENE-RESPONSE-FACTOR1 promoter. Belongs to the EIN3 family. (584 aa)
RGADELLA protein RGA; Probable transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Positively regulates XERICO expression in seeds. Upon GA application, it is degraded by the proteasome, allowing the GA signaling pathway. Compared to other DELLA proteins, it is the most sensitive to GA application. No effect of the BOI proteins on its stability. Its activity is probably regulated by other phytohormones such as auxin and ethylene, attenu [...] (587 aa)
T11I18.16Pyruvate kinase; Belongs to the pyruvate kinase family. (510 aa)
GID2F-box protein GID2; Essential component of the SCF-type E3 ligase complex, SCF(GID2), a complex that positively regulates the gibberellin signaling pathway. Upon gibberellin treatment, the SCF(GID2) complex mediates the ubiquitination and subsequent degradation of DELLA proteins (GAI, RGA and RGL2), some repressors of the gibberellin pathway, leading to activate the pathway. (151 aa)
SCL14Scarecrow-like protein 14; Probable transcription factor involved in plant development. (769 aa)
ARF9Auxin response factor 9; Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. (638 aa)
AGO10Protein argonaute 10; Involved in RNA-mediated post-transcriptional gene silencing (PTGS). Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as a microRNA (miRNA) or small interfering RNA (siRNA). RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression. Required for reliable formation of primary and axillary shoot apical meristems. Specifies leaf adaxial identity by repressing the miR165 and miR166 microRNAs in the embryonic shoot apex, in the shoot apical meristem (SAM) and [...] (988 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.