STRINGSTRING
T29J13.130 T29J13.130 SUS5 SUS5 EIN3 EIN3 SRK2J SRK2J CYCD3-1 CYCD3-1 SRK2A SRK2A SRK2G SRK2G SUS1 SUS1 NPR1 NPR1 PIP PIP SUS2 SUS2 CWINV2 CWINV2 BFRUCT4 BFRUCT4 SRK2D SRK2D SRK2I SRK2I PSBW PSBW PSBP1 PSBP1 BFRUCT3 BFRUCT3 CWINV1 CWINV1 NPR4 NPR4 CWINV3 CWINV3 IPK IPK CER3 CER3 NPR3 NPR3 ERF1B ERF1B PIF4 PIF4 CWINV4 CWINV4 CWINV6 CWINV6 SRK2E SRK2E AUX1 AUX1 SRK2B SRK2B SRK2H SRK2H SUS6 SUS6 CWINV5 CWINV5 SUS4 SUS4 SUS3 SUS3 NPR6 NPR6 SRK2C SRK2C SRK2F SRK2F NPR2 NPR2 PSBS PSBS NPR5 NPR5
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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T29J13.130Histidine containing phosphotransfer protein. (114 aa)
SUS5Sucrose synthase 5; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Functions in callose synthesis at the site of phloem sieve elements. (836 aa)
EIN3Protein ETHYLENE INSENSITIVE 3; Probable transcription factor acting as a positive regulator in the ethylene response pathway. Is required for ethylene responsiveness in adult plant tissues. Binds a primary ethylene response element present in the ETHYLENE-RESPONSE-FACTOR1 promoter with consequence to activate the transcription of this gene. (628 aa)
SRK2JSerine/threonine-protein kinase SRK2J; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (339 aa)
CYCD3-1Cyclin-D3-1; Involved in the control of the cell cycle at the G1/S (start) transition. Activates the G1/S phase transition in response to cytokinin hormone signal, but declines in response to sucrose starvation leading to G1 arrest. Involved in the induction of mitotic cell division. Plays an important role in the switch from cell proliferation to the final stages of differentiation during plant development. May not be involved in the activation of cell cycle in the root apical meristem (RAM) in the early phase of seed germination. Promotes divisions in the guard cells (GCs) after the [...] (376 aa)
SRK2ASerine/threonine-protein kinase SRK2A. (363 aa)
SRK2GSerine/threonine-protein kinase SRK2G; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (353 aa)
SUS1Sucrose synthase 1; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways; Belongs to the glycosyltransferase 1 family. Plant sucrose synthase subfamily. (808 aa)
NPR1Regulatory protein NPR1; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Key positive regulator of the SA-dependent signaling pathway that negatively regulates JA-dependent signaling pathway. Mediates the binding of TGA factors to the as-1 motif found in the pathogenesis-related PR-1 gene, leading to the transcriptional regulation of the gene defense. Controls the onset of systemic acquired resistance (SAR). Upon SAR induction, [...] (593 aa)
PIPProline iminopeptidase; Specifically catalyzes the removal of N-terminal proline residues from peptides; Belongs to the peptidase S33 family. (380 aa)
SUS2Sucrose synthase 2; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Modulates metabolic homeostasis and directs carbon towards starch synthesis in developing seeds. (807 aa)
CWINV2Beta-fructofuranosidase, insoluble isoenzyme CWINV2. (590 aa)
BFRUCT4Acid beta-fructofuranosidase 4, vacuolar; Possible role in the continued mobilization of sucrose to sink organs. Regulates root elongation. (664 aa)
SRK2DSerine/threonine-protein kinase SRK2D; Together with SRK2I, key component and activator of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as seed germination, Pro accumulation, root growth inhibition, dormancy and seedling growth, and, to a lesser extent, stomatal closure; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (362 aa)
SRK2ISerine/threonine-protein kinase SRK2I; Together with SRK2D, key component and activator of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as seed germination, Pro accumulation, root growth inhibition, dormancy and seedling growth, and, to a lesser extent, stomatal closure. (361 aa)
PSBWPhotosystem II reaction center W protein, chloroplastic; Stabilizes dimeric photosystem II (PSII). In its absence no dimeric PSII accumulates and there is a reduction of monomeric PSII. Belongs to the psbW family. (133 aa)
PSBP1Oxygen-evolving enhancer protein 2-1, chloroplastic; May be involved in the regulation of photosystem II; Belongs to the psbP family. (263 aa)
BFRUCT3Acid beta-fructofuranosidase 3, vacuolar; Possible role in the continued mobilization of sucrose to sink organs. (648 aa)
CWINV1Beta-fructofuranosidase, insoluble isoenzyme CWINV1; Beta-fructofuranosidase that can use sucrose and 1-kestose, and, to a lower extent, neokestose and levan, as substrates, but not inuline; Belongs to the glycosyl hydrolase 32 family. (584 aa)
NPR4Regulatory protein NPR4; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Involved in the regulation of basal defense responses against pathogens, and may be implicated in the cross-talk between the SA- and JA-dependent signaling pathways. (574 aa)
CWINV3Beta-fructofuranosidase, insoluble isoenzyme CWINV3; 6-fructan exohydrolase that can use phlein, levan, neokestose, levanbiose, 6-kestose, and 1-kestose as substrates. (594 aa)
IPKIsopentenyl phosphate kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the universal five-carbon isoprenoid building block of all natural isoprenoids. Acts in parallel with the mevalonate (MVA) pathway and plays an important role in regulating the formation of both MVA and methylerythritol phosphate (MEP) pathway- derived terpenoid compounds by controlling the ratio of isopentenyl phosphate (IP) and dimethylallyl phosphate (DMAP) to isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Controls the levels of IP and DMAP that are competitive inhibitors of [...] (332 aa)
CER3Very-long-chain aldehyde decarbonylase CER3; Involved in cuticule membrane and wax production, and in the typhine and sopropollenin biosynthesis of pollen. Core components of a very-long-chain alkane synthesis complex. May be the fatty acid reductase responsible for aldehyde formation. Belongs to the sterol desaturase family. (632 aa)
NPR3Regulatory protein NPR3; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Involved in the regulation of basal defense responses against pathogens. (586 aa)
ERF1BEthylene-responsive transcription factor 1B; Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression during the plant development, and/or mediated by stress factors and by components of stress signal transduction pathways. Seems to be a key integrator of ethylene and jasmonate signals in the regulation of ethylene/jasmonate-dependent defenses. Can mediate resistance to necrotizing fungi (Botrytis cinerea and Plectosphaerella cucumerina) and to soil borne fungi (Fusarium oxysporum conglutinans and Fus [...] (218 aa)
PIF4Transcription factor PIF4; Transcription factor acting negatively in the phytochrome B signaling pathway. May regulate the expression of a subset of genes involved in cell expansion by binding to the G-box motif (By similarity). Activated by CRY1 and CRY2 in response to low blue light (LBL) by direct binding at chromatin on E-box variant 5'-CA[CT]GTG-3' to stimulate specific gene expression to adapt global physiology (e.g. hypocotyl elongation in low blue light). Belongs to the bHLH protein family. (430 aa)
CWINV4Beta-fructofuranosidase, insoluble isoenzyme CWINV4. (591 aa)
CWINV6Beta-fructofuranosidase, insoluble isoenzyme CWINV6; 6 and 1-fructan exohydrolase that can degrade both inulin and levan-type fructans, such as phlein, levan, neokestose, levanbiose, 6- kestose, 1-kestose, inulin, and 1,1-nystose. (550 aa)
SRK2ESerine/threonine-protein kinase SRK2E; Activator of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomata closure in response to drought, darkness, high CO(2), plant pathogens, or decreases in atmospheric relative humidity (RH). Involved in the resistance to drought by avoiding water loss. Required for the stomata closure mediated by pathogen-associated molecular pattern (PAMPs) (e.g. flg22 and LPS) of pathogenic bacteria such as P.syringae pv. tomato (Pst) and E.coli O157:H7. As a plant defense process, stomata are closed transiently in order [...] (362 aa)
AUX1Auxin transporter protein 1; Carrier protein involved in proton-driven auxin influx. Mediates the formation of auxin gradient from developing leaves (site of auxin biosynthesis) to tips by contributing to the loading of auxin in vascular tissues and facilitating acropetal (base to tip) auxin transport within inner tissues of the root apex, and basipetal (tip to base) auxin transport within outer tissues of the root apex. Unloads auxin from the mature phloem to deliver the hormone to the root meristem via the protophloem cell files. Coordinated subcellular localization of AUX1 is regula [...] (485 aa)
SRK2BSerine/threonine-protein kinase SRK2B; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (361 aa)
SRK2HSerine/threonine-protein kinase SRK2H; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (360 aa)
SUS6Sucrose synthase 6; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Functions in callose synthesis at the site of phloem sieve elements. (942 aa)
CWINV5Beta-fructofuranosidase, insoluble isoenzyme CWINV5. (572 aa)
SUS4Sucrose synthase 4; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways; Belongs to the glycosyltransferase 1 family. Plant sucrose synthase subfamily. (808 aa)
SUS3Sucrose synthase 3; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Modulates metabolic homeostasis and direct carbon towards starch synthesis in developing seeds. (809 aa)
NPR6Regulatory protein NPR6; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Acts redundantly with BOP2. BOP1/2 promote leaf and floral meristem fate and determinacy in a pathway targeting AP1 and AGL24. BOP1/2 act as transcriptional co-regulators through direct interaction with TGA factors, including PAN, a direct regulator of AP1. Controls lateral organ fate through positive regulation of adaxial-abaxial polarity genes ATHB-14/PHB [...] (467 aa)
SRK2CSerine/threonine-protein kinase SRK2C; Involved in gene regulation and confers tolerance to drought and osmotic stress; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (343 aa)
SRK2FSerine/threonine-protein kinase SRK2F; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (350 aa)
NPR2Regulatory protein NPR2; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. (600 aa)
PSBSPhotosystem II 22 kDa protein, chloroplastic; Plays an important role in non-photochemical quenching, a process maintains the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage. Is not necessary for efficient light harvesting and photosynthesis. Belongs to the ELIP/psbS family. (265 aa)
NPR5Regulatory protein NPR5; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Acts redundantly with BOP2. BOP1/2 promote leaf and floral meristem fate and determinacy in a pathway targeting AP1 and AGL24. BOP1/2 act as transcriptional co-regulators through direct interaction with TGA factors, including PAN, a direct regulator of AP1. Controls lateral organ fate through positive regulation of adaxial-abaxial polarity genes ATHB-14/PHB [...] (491 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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