STRINGSTRING
B3H7M7_ARATH B3H7M7_ARATH RPT5B RPT5B SYP23 SYP23 TBL26 TBL26 ARD1 ARD1 VAMP725 VAMP725 JAL23 JAL23 LHCB1.1 LHCB1.1 VHA-B1 VHA-B1 GPA1 GPA1 CDKA-1 CDKA-1 TUBB4 TUBB4 BCA2 BCA2 GB1 GB1 HXK2 HXK2 CKA1 CKA1 STR15 STR15 HXK1 HXK1 RHIP1 RHIP1 ARD4 ARD4 RGS1 RGS1 SYT5 SYT5 PHL3 PHL3 WNK10 WNK10 PVA11 PVA11 WNK8 WNK8 T14P1.13 T14P1.13 F15I1.10 F15I1.10 GAMMACA2 GAMMACA2 WNK1 WNK1 GG1 GG1 SYP31 SYP31 ABIL4 ABIL4 TOR TOR TOZ TOZ T20H2.11 T20H2.11 PRN1 PRN1 F18O22.30 F18O22.30 EXO70A1 EXO70A1 ABIL2 ABIL2 MBP1 MBP1 VOZ1 VOZ1 VOZ2 VOZ2 ANN1 ANN1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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B3H7M7_ARATHCorepressor. (170 aa)
RPT5B26S proteasome regulatory subunit 6A homolog B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (423 aa)
SYP23Syntaxin-23; May function in the docking or fusion of transport vesicles with the prevacuolar membrane. (255 aa)
TBL26Protein trichome birefringence-like 26; May be involved in the O-acetylation of mannan. May act as a bridging protein that binds pectin and other cell wall polysaccharides. Probably involved in maintaining esterification of pectins (By similarity). (442 aa)
ARD11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 1; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (199 aa)
VAMP725Vesicle-associated membrane protein 725; Involved in the targeting and/or fusion of transport vesicles to their target membrane. (285 aa)
JAL23Jacalin-related lectin 23; Polymerizer-type lectin that may facilitate the correct polymerization and activation of BGLU23/PYK10 upon tissue damage. (459 aa)
LHCB1.1Chlorophyll a-b binding protein 2, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated; Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family. (267 aa)
VHA-B1V-type proton ATPase subunit B1; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (486 aa)
GPA1Guanine nucleotide-binding protein alpha-1 subunit; Exhibits a fast rate of basal nucleotide exchange. Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Together with GCR1, may regulate the cell cycle via a signaling cascade that uses phosphatidylinositol-specific phospholipase C (PI-PLC) as an effector and inositol 1,4,5-trisphosphate (IP(3)) as a second messenger. Promotes abscisic acid (ABA) responses in guard cells. But, together with GCR1 and GB1, acts as a negative regulator of ABA during seed ge [...] (383 aa)
CDKA-1Cyclin-dependent kinase A-1; Involved in the control of the cell cycle. Essential for both G1/S and G2/M (mitosis) phase transitions. Functions in cell morphogenesis as well as cell proliferation. Required for cell division (entry into mitosis) of the generative cell in male gametogenesis. Required to trigger guard mother cells (GMC) symmetric divisions at the late stage of stomatal development, probably via the regulation of G1 to S transition in the cell cycle. Required for the function of SPCH in entering the stomatal lineage. Promotes divisions in the guard cells (GCs) after the gu [...] (294 aa)
TUBB4Tubulin beta-4 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Belongs to the tubulin family. (444 aa)
BCA2Beta carbonic anhydrase 2, chloroplastic; Reversible hydration of carbon dioxide. This isoform ensures the supply of bicarbonate for pep carboxylase; Belongs to the beta-class carbonic anhydrase family. (331 aa)
GB1Guanine nucleotide-binding protein subunit beta; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Together with GCR1 and GPA1, acts as a negative regulator of ABA during seed germination and early seedling development. The heterotrimeric G-protein controls defense responses to necrotrophic and vascular fungi probably by modulating cell wall-related genes expression (e. [...] (377 aa)
HXK2Hexokinase-2; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells ; Belongs to the hexokinase family. (502 aa)
CKA1Casein kinase II subunit alpha-1; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates casein in vitro. The alpha chain contains the catalytic site. The tetrameric holoenzyme CK2, composed of two alpha and two beta subunits, phosphorylates the transcription factor GBFl, resulting in stimulation of its DNA binding activity. CK2 phosphorylates the transcription factor PIF1 after an exposure to light, resulting in a proteasome-dependent degradation of PIF1 and promotion of photomorphogenesis. CK2 phosph [...] (409 aa)
STR15Rhodanese-like domain-containing protein 15, chloroplastic. (182 aa)
HXK1Hexokinase-1; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells. Promotes roots and leaves growth. Belongs to the hexokinase family. (496 aa)
RHIP1RGS1-HXK1-interacting protein 1; Required for some glucose-regulated gene expression, being a physical connection between RGS1 and HXK1 in sugar signaling. Prevents roots and inflorecences growth. (263 aa)
ARD41,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 4; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (187 aa)
RGS1Regulator of G-protein signaling 1; Glucose-regulated GTPase-accelerating protein (GAP) for the GTP-bound self-activating heterotrimeric G alpha protein GPA1. Cooperates with G beta-gamma dimers to maintain an unactivated but fully functional pool of GPA1. Phosphorylation-dependent endocytosis of RGS1 physically uncouples the two proteins, resulting in signal activation. Free AGB1 is essential, but not sufficient, for RGS1 endocytosis. Modulates cell proliferation, abscisic acid (ABA) and drought stress signal transduction by acting in a hexokinase- independent glucose-signaling pathwa [...] (459 aa)
SYT5Synaptotagmin-5; May be involved in membrane trafficking. (560 aa)
PHL3Protein PHR1-LIKE 3; Transcriptional activator. Probable component of the central regulatory system controlling transcriptional responses to Pi starvation. Binds in a sequence- specific manner to phosphate starvation-regulated promoters. Required for female gametophyte development and function. (292 aa)
WNK10Probable serine/threonine-protein kinase WNK10; May regulate flowering time by modulating the photoperiod pathway. (524 aa)
PVA11Vesicle-associated protein 1-1, N-terminally processed; Part of a membrane-cytoskeletal adapter complex that forms a bridge between the endoplasmic reticulum and the plasma membrane. Associates with microtubules. (256 aa)
WNK8Serine/threonine-protein kinase WNK8; Regulates flowering time by modulating the photoperiod pathway. Phosphorylates the vacuolar ATPase subunit C (VATC) and RGS1. Regulates EDM2 that, in turn, modulates development processes. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WNK subfamily. (563 aa)
T14P1.13Alanine-tRNA ligase. (272 aa)
F15I1.10GDSL esterase/lipase At1g54020. (372 aa)
GAMMACA2Gamma carbonic anhydrase 2, mitochondrial; Enzyme involved in the catabolism of H(2)CO(3) but that does not mediates the reversible hydration of carbon dioxide. Mediates complex I assembly in mitochondria and respiration. Binds HCO(3)-. Required for male fertility during anther development and dehiscence to regulate the secondary thickenings of the endothecial cell wall, probably by modulating H(2)O(2)-dependent lignin polymerization; Belongs to the gamma-class carbonic anhydrase family. (278 aa)
WNK1Serine/threonine-protein kinase WNK1; Regulates flowering time by modulating the photoperiod pathway. Phosphorylates APRR3. (700 aa)
GG1Guanine nucleotide-binding protein subunit gamma 1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Involved in the abscisic acid (ABA) and ethylene signaling pathways. Regulates acropetal transport of auxin (IAA) in roots and hypocotyls, and thus modulates root architecture (e.g. lateral root formation). The heterotrimeric G-protein controls defense responses to necr [...] (98 aa)
SYP31Syntaxin-31; Vesicle trafficking protein that functions in the secretory pathway; Belongs to the syntaxin family. (336 aa)
ABIL4Protein ABIL4; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex (By similarity). (279 aa)
TORSerine/threonine-protein kinase TOR; Essential cell growth regulator that controls development from early embryo to seed production. Controls plant growth in environmental stress conditions. Acts through the phosphorylation of downstream effectors that are recruited by the binding partner RAPTOR. Acts by activating transcription, protein synthesis and ribosome biogenesis, and inhibiting mRNA degradation and autophagy. Can phosphorylate TAP46, a regulatory subunit of protein phosphatase 2A that modulates cell growth and survival. Involved in modulating the transition from heterotrophic [...] (2481 aa)
TOZTransducin family protein / WD-40 repeat family protein. (876 aa)
T20H2.11DNA ligase-like protein. (285 aa)
PRN1Pirin-1; Involved in abscisic acid signal transduction. Plays a role in seed germination and early seedling development. Involved in the blue light (BL) signaling; Belongs to the pirin family. (287 aa)
F18O22.30Thioredoxin superfamily protein. (256 aa)
EXO70A1Exocyst complex component EXO70A1; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane during regulated or polarized secretion. Involved in polarized cell growth and organ morphogenesis. Involved in polarized cell growth and organ morphogenesis. During cytokinesis, involved in cell plate initiation, cell plate maturation and formation of new primary cell wall. Participates in polarized pectin delivery required for the polarized development of the mucilage-producing volcano cells of the seed coat. Involved in the recycli [...] (638 aa)
ABIL2Protein ABIL2; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex (By similarity); Belongs to the ABI family. (312 aa)
MBP1Myrosinase-binding protein 1. (462 aa)
VOZ1Transcription factor VOZ1; Transcriptional activator acting positively in the phytochrome B signaling pathway. Functions redundantly with VOZ2 to promote flowering downstream of phytochrome B (phyB). Down-regulates 'FLOWERING LOCUS C' (FLC) and up-regulates 'FLOWERING LOCUS T' (FT). Binds to the 38-bp cis-acting region of the AVP1 gene. Interacts with phyB in the cytoplasm and is translocated to the nucleus at signal transmission, where it is subjected to degradation in a phytochrome- dependent manner. (486 aa)
VOZ2Transcription factor VOZ2; Transcriptional activator acting positively in the phytochrome B signaling pathway. Functions redundantly with VOZ1 to promote flowering downstream of phytochrome B (phyB). Down-regulates 'FLOWERING LOCUS C' (FLC) and up-regulates 'FLOWERING LOCUS T' (FT). Binds to the 38-bp cis-acting region of the AVP1 gene. Binds as a dimer to the palindromic sequence 5'-GCGTNNNNNNNACGC-3'. Interacts with phyB in the cytoplasm and is translocated to the nucleus at signal transmission, where it is subjected to degradation in a phytochrome- dependent manner. (450 aa)
ANN1Annexin D1; Has a peroxidase activity. May act in counteracting oxidative stress. May also mediate regulated, targeted secretion of Golgi-derived vesicles during seedling development. (317 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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