Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Protein BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE; Regulates asymmetric cell division (ACD), especially in stomatal-lineage cells, probably by modulating accumulation and subcellular polarization of POLAR and SPCH. Mediates an attenuation of MAPK signaling upon polarization of POLAR and ASK7/BIN2 in stomatal lineage ground cells (SLGCs) undergoing ACD, and relieves BIN2 inhibition of SPCH in the nucleus. When phosphorylated, functions as a scaffold and recruits the MAPKKK YODA, MPK3 and MPK6 to spatially reorganize the MAPK signaling pathway at the cortex of cells undergoing ACD. C [...]

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Cyclin-D3-1; Involved in the control of the cell cycle at the G1/S (start) transition. Activates the G1/S phase transition in response to cytokinin hormone signal, but declines in response to sucrose starvation leading to G1 arrest. Involved in the induction of mitotic cell division. Plays an important role in the switch from cell proliferation to the final stages of differentiation during plant development. May not be involved in the activation of cell cycle in the root apical meristem (RAM) in the early phase of seed germination. Promotes divisions in the guard cells (GCs) after the [...]

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Protein EPIDERMAL PATTERNING FACTOR 1; Controls stomatal patterning. Regulates asymmetric cell division during guard cell differentiation. Mediates stomatal development inhibition. Not cleaved by the protease CRSP (AC Q9LNU1). MEPF1: mobile signal controlling stomatal development in a non-cell-autonomous manner. Uses ERL1 as major receptor. May act by competing with somatogen (AC Q9SV72) for the same receptor, TMM (AC Q9SSD1). Belongs to the plant cysteine rich small secretory peptide family. Epidermal patterning factor subfamily.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Protein EPIDERMAL PATTERNING FACTOR 2; Controls stomatal patterning. Regulates the number of cells that enter, and remain in, the stomatal lineage by inhibiting protodermal cells from adopting the meristemoid mother cell (MMC) fate in a non-cell-autonomous manner. Mediates stomatal development inhibition. MEPF2: mobile signal controlling stomatal development in a non-cell-autonomous manner. Uses ERECTA as major receptor. Inactivated by cleavage by CRSP (AC Q9LNU1). May act by competing with somatogen (AC Q9SV72) for the same receptor, TMM (AC Q9SSD1).

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

EPIDERMAL PATTERNING FACTOR-like protein 9; [Stomagen]: Positively regulates stomatal density and patterning. Acts by competing with EPF2 (AC Q8LC53) for the same receptors, ERECTA (AC Q42371) and TMM (AC Q9SSD1). Not cleaved by the protease CRSP (AC Q9LNU1). Belongs to the plant cysteine rich small secretory peptide family. Epidermal patterning factor subfamily.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Transcription factor FAMA; Transcription activator. Together with MYB88 and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity. Together with SPCH and MUTE, regulates the stomata formation. Required to promote differentiation and morphogenesis of stomatal guard cells and to halt proliferative divisions in their immediate precursors. Mediates the formation of stomata. Prevents histone H3K27me3 marks and derepresses stem cell gene expression.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Transcription factor MUTE; Transcription factor. Together with FMA and SPCH, regulates the stomata formation. Required for the differentiation of stomatal guard cells, by promoting successive asymmetric cell divisions and the formation of guard mother cells. Promotes the conversion of the leaf epidermis into stomata.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Transcription factor ICE1; Transcriptional activator that regulates the cold-induced transcription of CBF/DREB1 genes. Binds specifically to the MYC recognition sites (5'-CANNTG-3') found in the CBF3/DREB1A promoter. Mediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA. Functions as a dimer with SPCH during stomatal initiation.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Transcription factor SCREAM2; Mediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA. Functions as a dimer with SPCH during stomatal initiation.

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Transcription factor SPEECHLESS; Transcription factor acting as an integration node for stomata and brassinosteroid (BR) signaling pathways to control stomatal initiation and development. Activates transcription when in the presence of SCRM/ICE1. Functions as a dimer with SCRM or SCRM2 during stomatal initiation. Required for the initiation, the spacing and the formation of stomata, by promoting the first asymmetric cell divisions. Together with FMA and MUTE, modulates the stomata formation. Involved in the regulation of growth reduction under osmotic stress (e.g. mannitol), associated [...]

Protein BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE; Regulates asymmetric cell division (ACD), especially in stomatal-lineage cells, probably by modulating accumulation and subcellular polarization of POLAR and SPCH. Mediates an attenuation of MAPK signaling upon polarization of POLAR and ASK7/BIN2 in stomatal lineage ground cells (SLGCs) undergoing ACD, and relieves BIN2 inhibition of SPCH in the nucleus. When phosphorylated, functions as a scaffold and recruits the MAPKKK YODA, MPK3 and MPK6 to spatially reorganize the MAPK signaling pathway at the cortex of cells undergoing ACD. C [...]

Shaggy-related protein kinase eta; Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5. Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in v [...]

Protein BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE; Regulates asymmetric cell division (ACD), especially in stomatal-lineage cells, probably by modulating accumulation and subcellular polarization of POLAR and SPCH. Mediates an attenuation of MAPK signaling upon polarization of POLAR and ASK7/BIN2 in stomatal lineage ground cells (SLGCs) undergoing ACD, and relieves BIN2 inhibition of SPCH in the nucleus. When phosphorylated, functions as a scaffold and recruits the MAPKKK YODA, MPK3 and MPK6 to spatially reorganize the MAPK signaling pathway at the cortex of cells undergoing ACD. C [...]

CO(2)-response secreted protease; Mediates CO(2)-controlled stomatal development by cleaving peptide EPF2 (AC Q8LC53). Not active on peptides EPF1 (AC Q8S8I4) or stomagen (AC Q9SV72).

Protein BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE; Regulates asymmetric cell division (ACD), especially in stomatal-lineage cells, probably by modulating accumulation and subcellular polarization of POLAR and SPCH. Mediates an attenuation of MAPK signaling upon polarization of POLAR and ASK7/BIN2 in stomatal lineage ground cells (SLGCs) undergoing ACD, and relieves BIN2 inhibition of SPCH in the nucleus. When phosphorylated, functions as a scaffold and recruits the MAPKKK YODA, MPK3 and MPK6 to spatially reorganize the MAPK signaling pathway at the cortex of cells undergoing ACD. C [...]

Protein EPIDERMAL PATTERNING FACTOR 1; Controls stomatal patterning. Regulates asymmetric cell division during guard cell differentiation. Mediates stomatal development inhibition. Not cleaved by the protease CRSP (AC Q9LNU1). MEPF1: mobile signal controlling stomatal development in a non-cell-autonomous manner. Uses ERL1 as major receptor. May act by competing with somatogen (AC Q9SV72) for the same receptor, TMM (AC Q9SSD1). Belongs to the plant cysteine rich small secretory peptide family. Epidermal patterning factor subfamily.

Protein BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE; Regulates asymmetric cell division (ACD), especially in stomatal-lineage cells, probably by modulating accumulation and subcellular polarization of POLAR and SPCH. Mediates an attenuation of MAPK signaling upon polarization of POLAR and ASK7/BIN2 in stomatal lineage ground cells (SLGCs) undergoing ACD, and relieves BIN2 inhibition of SPCH in the nucleus. When phosphorylated, functions as a scaffold and recruits the MAPKKK YODA, MPK3 and MPK6 to spatially reorganize the MAPK signaling pathway at the cortex of cells undergoing ACD. C [...]

Protein EPIDERMAL PATTERNING FACTOR 2; Controls stomatal patterning. Regulates the number of cells that enter, and remain in, the stomatal lineage by inhibiting protodermal cells from adopting the meristemoid mother cell (MMC) fate in a non-cell-autonomous manner. Mediates stomatal development inhibition. MEPF2: mobile signal controlling stomatal development in a non-cell-autonomous manner. Uses ERECTA as major receptor. Inactivated by cleavage by CRSP (AC Q9LNU1). May act by competing with somatogen (AC Q9SV72) for the same receptor, TMM (AC Q9SSD1).

Protein BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE; Regulates asymmetric cell division (ACD), especially in stomatal-lineage cells, probably by modulating accumulation and subcellular polarization of POLAR and SPCH. Mediates an attenuation of MAPK signaling upon polarization of POLAR and ASK7/BIN2 in stomatal lineage ground cells (SLGCs) undergoing ACD, and relieves BIN2 inhibition of SPCH in the nucleus. When phosphorylated, functions as a scaffold and recruits the MAPKKK YODA, MPK3 and MPK6 to spatially reorganize the MAPK signaling pathway at the cortex of cells undergoing ACD. C [...]

EPIDERMAL PATTERNING FACTOR-like protein 9; [Stomagen]: Positively regulates stomatal density and patterning. Acts by competing with EPF2 (AC Q8LC53) for the same receptors, ERECTA (AC Q42371) and TMM (AC Q9SSD1). Not cleaved by the protease CRSP (AC Q9LNU1). Belongs to the plant cysteine rich small secretory peptide family. Epidermal patterning factor subfamily.

Protein BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE; Regulates asymmetric cell division (ACD), especially in stomatal-lineage cells, probably by modulating accumulation and subcellular polarization of POLAR and SPCH. Mediates an attenuation of MAPK signaling upon polarization of POLAR and ASK7/BIN2 in stomatal lineage ground cells (SLGCs) undergoing ACD, and relieves BIN2 inhibition of SPCH in the nucleus. When phosphorylated, functions as a scaffold and recruits the MAPKKK YODA, MPK3 and MPK6 to spatially reorganize the MAPK signaling pathway at the cortex of cells undergoing ACD. C [...]

LRR receptor-like serine/threonine-protein kinase ERL2; Receptor kinase that regulates inflorescence architecture and organ shape as well as stomatal patterning, including density and clustering, together with ERL1 and ER.

Protein BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE; Regulates asymmetric cell division (ACD), especially in stomatal-lineage cells, probably by modulating accumulation and subcellular polarization of POLAR and SPCH. Mediates an attenuation of MAPK signaling upon polarization of POLAR and ASK7/BIN2 in stomatal lineage ground cells (SLGCs) undergoing ACD, and relieves BIN2 inhibition of SPCH in the nucleus. When phosphorylated, functions as a scaffold and recruits the MAPKKK YODA, MPK3 and MPK6 to spatially reorganize the MAPK signaling pathway at the cortex of cells undergoing ACD. C [...]

Transcription factor FAMA; Transcription activator. Together with MYB88 and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity. Together with SPCH and MUTE, regulates the stomata formation. Required to promote differentiation and morphogenesis of stomatal guard cells and to halt proliferative divisions in their immediate precursors. Mediates the formation of stomata. Prevents histone H3K27me3 marks and derepresses stem cell gene expression.

Protein BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE; Regulates asymmetric cell division (ACD), especially in stomatal-lineage cells, probably by modulating accumulation and subcellular polarization of POLAR and SPCH. Mediates an attenuation of MAPK signaling upon polarization of POLAR and ASK7/BIN2 in stomatal lineage ground cells (SLGCs) undergoing ACD, and relieves BIN2 inhibition of SPCH in the nucleus. When phosphorylated, functions as a scaffold and recruits the MAPKKK YODA, MPK3 and MPK6 to spatially reorganize the MAPK signaling pathway at the cortex of cells undergoing ACD. C [...]

Homeobox-leucine zipper protein HDG2; Probable transcription factor.

Protein BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE; Regulates asymmetric cell division (ACD), especially in stomatal-lineage cells, probably by modulating accumulation and subcellular polarization of POLAR and SPCH. Mediates an attenuation of MAPK signaling upon polarization of POLAR and ASK7/BIN2 in stomatal lineage ground cells (SLGCs) undergoing ACD, and relieves BIN2 inhibition of SPCH in the nucleus. When phosphorylated, functions as a scaffold and recruits the MAPKKK YODA, MPK3 and MPK6 to spatially reorganize the MAPK signaling pathway at the cortex of cells undergoing ACD. C [...]

Transcription factor MUTE; Transcription factor. Together with FMA and SPCH, regulates the stomata formation. Required for the differentiation of stomatal guard cells, by promoting successive asymmetric cell divisions and the formation of guard mother cells. Promotes the conversion of the leaf epidermis into stomata.

Protein BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE; Regulates asymmetric cell division (ACD), especially in stomatal-lineage cells, probably by modulating accumulation and subcellular polarization of POLAR and SPCH. Mediates an attenuation of MAPK signaling upon polarization of POLAR and ASK7/BIN2 in stomatal lineage ground cells (SLGCs) undergoing ACD, and relieves BIN2 inhibition of SPCH in the nucleus. When phosphorylated, functions as a scaffold and recruits the MAPKKK YODA, MPK3 and MPK6 to spatially reorganize the MAPK signaling pathway at the cortex of cells undergoing ACD. C [...]

Transcription factor MYB88; Transcription factor that binds to DNA in promoters cis- regulatory element 5'-GGCGCGC-3' of cell cycle genes, including cyclins, cyclin-dependent kinases (CDKs), and components of the pre- replication complex. Binds to DNA in promoters cis-regulatory element 5'-AGCCG-3' of auxin regulated genes (e.g. PIN3 and PIN7). Together with FAMA and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity. Represses the expression of the mitosis-inducing factors CDKB1-1 and CDKA-1, [...]