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F18O22.20 F18O22.20 A0A1P8ARU2 A0A1P8ARU2 B9DG91_ARATH B9DG91_ARATH SUC3 SUC3 F12L6.16 F12L6.16 PAL1 PAL1 PAL2 PAL2 PAL3 PAL3 NPR1 NPR1 HXK2 HXK2 HXK1 HXK1 ATHXK4 ATHXK4 NPR4 NPR4 SIZ1 SIZ1 PHO1-H4 PHO1-H4 ABCG31 ABCG31 BAD1 BAD1 NPR3 NPR3 SPX1 SPX1 PPT1 PPT1 PHO1 PHO1 HXK3 HXK3 HKL1 HKL1 GLT1 GLT1 EMS1 EMS1 NPR6 NPR6 DGD1 DGD1 STP8 STP8 WRKY46 WRKY46 PAL4 PAL4 NPR2 NPR2 ABCG9 ABCG9 HKL3 HKL3 NPR5 NPR5 TRI TRI
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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F18O22.20Ankyrin. (751 aa)
A0A1P8ARU2Phosphotransferase. (186 aa)
B9DG91_ARATHAT3G13950 protein. (207 aa)
SUC3Sucrose transport protein SUC3; Responsible for the transport of sucrose into the cell, with the concomitant uptake of protons (symport system). Can also transport maltose at a lesser rate. May also transport biotin. Probably involved in carpel maturation that leads to pod shatter and seed dispersal. Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2.4) family. (594 aa)
F12L6.16At2g39500/F12L6.16. (55 aa)
PAL1Phenylalanine ammonia-lyase 1; This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton; Belongs to the PAL/histidase family. (725 aa)
PAL2Phenylalanine ammonia-lyase 2; This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton; Belongs to the PAL/histidase family. (717 aa)
PAL3Phenylalanine ammonia-lyase 3; This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton. (694 aa)
NPR1Regulatory protein NPR1; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Key positive regulator of the SA-dependent signaling pathway that negatively regulates JA-dependent signaling pathway. Mediates the binding of TGA factors to the as-1 motif found in the pathogenesis-related PR-1 gene, leading to the transcriptional regulation of the gene defense. Controls the onset of systemic acquired resistance (SAR). Upon SAR induction, [...] (593 aa)
HXK2Hexokinase-2; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells ; Belongs to the hexokinase family. (502 aa)
HXK1Hexokinase-1; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells. Promotes roots and leaves growth. Belongs to the hexokinase family. (496 aa)
ATHXK4Hexokinase-4; Fructose and glucose phosphorylating enzyme (By similarity). May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol (By similarity). (502 aa)
NPR4Regulatory protein NPR4; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Involved in the regulation of basal defense responses against pathogens, and may be implicated in the cross-talk between the SA- and JA-dependent signaling pathways. (574 aa)
SIZ1E3 SUMO-protein ligase SIZ1; E3 SUMO protein ligase involved in regulation processes. Mediates SUMO/ attachment to PHR1, a MYB transcriptional activator controlling the phosphate deficiency responses. Functions as an upstream negative regulator of salicylic acid (SA) accumulation and subsequent SA-mediated systemic acquired resistance (SAR) signaling. Probably not involved in jasmonic acid (JA)-mediated defense response. Participates in abiotic stress-induced sumoylation. Controls heat shock-induced SUMO1 and SUMO2 conjugation and facilitates basal thermotolerance. Involved in freezing [...] (884 aa)
PHO1-H4Phosphate transporter PHO1 homolog 4; May transport inorganic phosphate (Pi); Belongs to the SYG1 (TC 2.A.94) family. (745 aa)
ABCG31ABC transporter G family member 31; May be a general defense protein; Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily. (1426 aa)
BAD1Ankyrin repeat-containing protein BDA1; Involved in plant defense. Required for basal resistance against Pseudomonas syringae pv. tomato DC3000. Required for resistance against nonpathogenic bacteria. May be involved in signaling components that function downstream of SNC2 and upstream of NPR1 and WRKY70 to regulate defense responses. (426 aa)
NPR3Regulatory protein NPR3; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Involved in the regulation of basal defense responses against pathogens. (586 aa)
SPX1SPX domain-containing protein 1; Plays a positive role in plant adaptation to phosphate starvation. Inhibits PHR1 DNA-binding activity in a Pi-dependent manner. (256 aa)
PPT1Phosphoenolpyruvate/phosphate translocator 1, chloroplastic; Phosphoenolpyruvate/phosphate translocator that transports phosphoenolpyruvate (PEP), 2-phosphoglycerate, 3-phosphoglycerate and dihydroxyacetone phosphate. Imports PEP to the chloroplast stroma as one substrate of the shikimate pathway, from which aromatic amino acids and a variety of secondary products derive. Required for correct leaf mesophyll cell development and expression of chlorophyll a/b binding protein 3 (CAB3). Belongs to the TPT transporter family. PPT (TC 2.A.7.9) subfamily. (408 aa)
PHO1Phosphate transporter PHO1; Inositol polyphosphate sensor that associates with transcription factors to regulate inorganic phosphate (Pi) starvation responses. Probably acts by binding inositol polyphosphate via its SPX domain. Acts as a Pi exporter, mediating efflux of Pi out of cells. Transfers Pi from the epidermal and cortical cells to the root xylem vessels. Involved in the transfer of Pi from roots to shoots. Involved in abscisic acid (ABA) induction of stomatal closure and ABA repression of stomatal opening. Belongs to the SYG1 (TC 2.A.94) family. (782 aa)
HXK3Hexokinase-like 1 protein; Fructose and glucose phosphorylating enzyme. Belongs to the hexokinase family. (493 aa)
HKL1Hexokinase-3; Fructose and glucose phosphorylating enzyme (By similarity). May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol (By similarity). (498 aa)
GLT1Glutamate synthase 1 [NADH], chloroplastic; Involved in glutamate biosynthesis. Required for non- photorespiratory ammonium assimilation. Probably involved in primary ammonium assimilation in roots. (2208 aa)
EMS1Leucine-rich repeat receptor protein kinase EMS1; Receptor with a serine/threonine-protein kinase activity required for the specification of the correct number of male archesporial initials and for the subsequent specification of tapetal and middle cell layer identities. In seeds, required for enhancing cell size and the rate of embryonic development. (1192 aa)
NPR6Regulatory protein NPR6; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Acts redundantly with BOP2. BOP1/2 promote leaf and floral meristem fate and determinacy in a pathway targeting AP1 and AGL24. BOP1/2 act as transcriptional co-regulators through direct interaction with TGA factors, including PAN, a direct regulator of AP1. Controls lateral organ fate through positive regulation of adaxial-abaxial polarity genes ATHB-14/PHB [...] (467 aa)
DGD1Digalactosyldiacylglycerol synthase 1, chloroplastic; Involved in the synthesis of diacylglycerol galactolipids that are specifically found in thylakoid membranes. Specific for alpha- glycosidic linkages. Responsible for the final assembly of galactolipids in photosynthetic membranes. Digalactosyldiacylglycerol (DGDG) provides stability to the photosystem I (PSI) complex, especially to the PsaA, PsaB, PsaC, PsaL and PsaH subunits. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. (808 aa)
STP8Sugar transport protein 8; Mediates an active uptake of hexoses, probably by sugar/hydrogen symport; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (507 aa)
WRKY46Probable WRKY transcription factor 46; Transcription factor involved in the regulation of osmotic stress responses and stomatal movement. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Positive regulator of EDS1-dependent defense against E.amylovora. Together with WRKY70 and WRKY53, promotes resistance to P.syringae, probably by enhancing salicylic acid (SA)- dependent genes. Contributes to the suppression of jasmonic acid (MeJA)-induced expression of PDF1.2. Together with WRKY54 and WRKY70, prom [...] (295 aa)
PAL4Phenylalanine ammonia-lyase 4; This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton; Belongs to the PAL/histidase family. (707 aa)
NPR2Regulatory protein NPR2; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. (600 aa)
ABCG9ABC transporter G family member 9. (638 aa)
HKL3Probable hexokinase-like 2 protein; Fructose and glucose phosphorylating enzyme. (493 aa)
NPR5Regulatory protein NPR5; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Acts redundantly with BOP2. BOP1/2 promote leaf and floral meristem fate and determinacy in a pathway targeting AP1 and AGL24. BOP1/2 act as transcriptional co-regulators through direct interaction with TGA factors, including PAN, a direct regulator of AP1. Controls lateral organ fate through positive regulation of adaxial-abaxial polarity genes ATHB-14/PHB [...] (491 aa)
TRITropinone reductase homolog At2g29330; Reductase active only on small flexible lipophilic carbonyls. No activity with cyclic monoterpenes, tropinone, nitrogen-containing tropinone analogs, tropine or pseudotropine as substrate. Belongs to the short-chain dehydrogenases/reductases (SDR) family. SDR65C subfamily. (260 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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