STRINGSTRING
TL29 TL29 BCA2 BCA2 GSH2 GSH2 CTIMC CTIMC F8L15_30 F8L15_30 ALDH6B2 ALDH6B2 GDH2-2 GDH2-2 AOX1A AOX1A CAT3 CAT3 GDH1-2 GDH1-2 LFNR2 LFNR2 GAMMACA3 GAMMACA3 NDB2 NDB2 BGLU21 BGLU21 MTERF15 MTERF15 GAMMACA2 GAMMACA2 NMAT1 NMAT1 LFNR1 LFNR1 MCO15.2 MCO15.2 GAMMACAL1 GAMMACAL1 CI51 CI51 GAMMACA1 GAMMACA1 BCAT4 BCAT4 MMDH2 MMDH2 TIM TIM GAMMACAL2 GAMMACAL2 BGLU23 BGLU23 BIR6 BIR6 CORI3 CORI3 TIM9 TIM9 TIM8 TIM8 ARGAH2 ARGAH2 ALAAT1 ALAAT1 PBP1 PBP1 INDH INDH NCS6 NCS6 GDCST GDCST GLDP2 GLDP2 CSY4 CSY4 BCA1 BCA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TL29Thylakoid lumenal 29 kDa protein, chloroplastic. (349 aa)
BCA2Beta carbonic anhydrase 2, chloroplastic; Reversible hydration of carbon dioxide. This isoform ensures the supply of bicarbonate for pep carboxylase; Belongs to the beta-class carbonic anhydrase family. (331 aa)
GSH2Glutathione synthetase, chloroplastic. (539 aa)
CTIMCTriosephosphate isomerase, cytosolic; Belongs to the triosephosphate isomerase family. (254 aa)
F8L15_30Succinate--CoA ligase [ADP-forming] subunit alpha-1, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (347 aa)
ALDH6B2Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial. (607 aa)
GDH2-2Glutamate dehydrogenase 2; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (411 aa)
AOX1AUbiquinol oxidase 1a, mitochondrial; Catalyzes the cyanide-resistant oxidation of ubiquinol and the reduction of molecular oxygen to water, but does not translocate protons and consequently is not linked to oxidative phosphorylation. Increases respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures. (354 aa)
CAT3Catalase-3; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide; Belongs to the catalase family. (492 aa)
GDH1-2Glutamate dehydrogenase 1; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (411 aa)
LFNR2Ferredoxin--NADP reductase, leaf isozyme 2, chloroplastic; Plays a key role in regulating the relative amounts of cyclic and non-cyclic electron flow to meet the demands of the plant for ATP and reducing power. (369 aa)
GAMMACA3Gamma carbonic anhydrase 3, mitochondrial; Enzyme involved in the catabolism of H(2)CO(3) but that does not mediates the reversible hydration of carbon dioxide. Mediates complex I assembly in mitochondria and respiration (By similarity). (258 aa)
NDB2External alternative NAD(P)H-ubiquinone oxidoreductase B2, mitochondrial; Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane (By similarity). Calcium-dependent NAD(P)H dehydrogenase; more efficient on NADH. Binds calcium ions. (582 aa)
BGLU21Beta-glucosidase 21; Beta-D-glucosidase active on scopolin >> esculin >> 4-MU- glucoside > DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates. (524 aa)
MTERF15Transcription termination factor MTERF15, mitochondrial; Transcription termination factor required for mitochondrial NAD2 intron 3 splicing and normal membrane respiratory chain Complex I activity. Essential for normal plant growth and development. Binds to RNA but not to double-stranded DNA. (445 aa)
GAMMACA2Gamma carbonic anhydrase 2, mitochondrial; Enzyme involved in the catabolism of H(2)CO(3) but that does not mediates the reversible hydration of carbon dioxide. Mediates complex I assembly in mitochondria and respiration. Binds HCO(3)-. Required for male fertility during anther development and dehiscence to regulate the secondary thickenings of the endothecial cell wall, probably by modulating H(2)O(2)-dependent lignin polymerization; Belongs to the gamma-class carbonic anhydrase family. (278 aa)
NMAT1Nuclear intron maturase 1, mitochondrial; Nuclear-encoded maturase required for splicing of group-II introns in mitochondria. Necessary for mitochondrial biogenesis during early developmental stages. Involved in the splicing of mitochondrial NAD4 transcripts. Required for trans-splicing of NAD1 intron 1 and also functions in cis-splicing of NAD2 intron 1 and NAD4 intron 2. Required for the regulation of fundamental metabolic pathways such as amino acid metabolism, triacylglycerol degradation and polysaccharide synthesis (cellulose and starch) during the early stage of plant growth. Imp [...] (711 aa)
LFNR1Ferredoxin--NADP reductase, leaf isozyme 1, chloroplastic; Plays a key role in regulating the relative amounts of cyclic and non-cyclic electron flow to meet the demands of the plant for ATP and reducing power; Belongs to the ferredoxin--NADP reductase type 1 family. (360 aa)
MCO15.22-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase); The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (464 aa)
GAMMACAL1Gamma carbonic anhydrase-like 1, mitochondrial; Involved in complex I assembly in mitochondria and respiration. (252 aa)
CI51NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (486 aa)
GAMMACA1Gamma carbonic anhydrase 1, mitochondrial; Enzyme involved in the catabolism of H(2)CO(3) but that does not mediates the reversible hydration of carbon dioxide. Mediates complex I assembly in mitochondria and respiration (By similarity). (275 aa)
BCAT4Methionine aminotransferase BCAT4; Converts 2-oxo acids to branched-chain amino acids. Shows activity with L-Leu, L-Ile and L-Val as amino donors and alpha-keto- glutarate as an amino acceptor, but no activity for D-isomers of Leu, Ile, Val, Asp, Glu or Ala. Acts on methionine and its derivatives and the corresponding 2-oxo acids. Catalyzes the initial deamination of methionine to 4-methylthio-2-oxobutyrate as well as the transamination of other typical intermediates of the methionine chain elongation pathway. (354 aa)
MMDH2Malate dehydrogenase 2, mitochondrial; Catalyzes a reversible NAD-dependent dehydrogenase reaction involved in central metabolism and redox homeostasis between organelle compartments (Probable). Required for carbon dioxide and energy partitioning in leaves. May limit photorespiration during the dark phase. Can convert 2-ketoglutarate to L-2-hydroxyglutarate in vitro. Belongs to the LDH/MDH superfamily. MDH type 1 family. (341 aa)
TIMTriosephosphate isomerase, chloroplastic; Belongs to the triosephosphate isomerase family. (315 aa)
GAMMACAL2Gamma carbonic anhydrase-like 2, mitochondrial; Involved in complex I assembly in mitochondria and respiration; Belongs to the gamma-class carbonic anhydrase family. (256 aa)
BGLU23Beta-glucosidase 23; Beta-D-glucosidase active on scopolin > esculin >> 4-MU- glucoside >> DIMBOA-glucoside. No activity with pNP-glucoside, oNP- glucoside and sinigrin as substrates. May possess beta-D-fucosidase activity. Required for the beneficial interaction with the endophytic fungus P.indica. May participate in the control of root colonization by P.indica by repressing defense responses and modulating other responses required for a mutualistic interaction. (524 aa)
BIR6Pentatricopeptide repeat-containing protein At3g48250, chloroplastic. (621 aa)
CORI3Cystine lyase CORI3; Possesses cystine lyase activity in vitro. Does not possess tyrosine aminotransferase, alanine aminotransferase, aspartate aminotransferase and tryptophan aminotransferase activities. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. (422 aa)
TIM9Mitochondrial import inner membrane translocase subunit TIM9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity). (93 aa)
TIM8Mitochondrial import inner membrane translocase subunit TIM8; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8- TIM13 complex mediates the import of some protein [...] (77 aa)
ARGAH2Arginase 2, chloroplastic/mitochondrial; Catalyzes the hydrolysis of L-arginine to urea and L- ornithine. The latter can be utilized in the urea cycle or as a precursor for the synthesis of both polyamines and proline (By similarity). Possesses agmatinase activity. Catalyzes the formation of putrescine from agmatine. (344 aa)
ALAAT1Alanine aminotransferase 1, mitochondrial; Major alanine aminotransferase in roots. (543 aa)
PBP1PYK10-binding protein 1; Inhibitor-type lectin that may regulate the correct polymerization of BGLU23/PYK10 upon tissue damage. Activates BGLU21, BGLU22 and BGLU23. (298 aa)
INDHINDH1(Iron-sulfur protein required for NADH dehydrogenase). (313 aa)
NCS6Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position; Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily. (355 aa)
GDCSTAminomethyltransferase, mitochondrial; The glycine decarboxylase (GDC) or glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (408 aa)
GLDP2Glycine dehydrogenase (decarboxylating) 2, mitochondrial; The glycine decarboxylase (GDC) or glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha- amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity). (1044 aa)
CSY4Citrate synthase 4, mitochondrial; Belongs to the citrate synthase family. (474 aa)
BCA1Beta carbonic anhydrase 1, chloroplastic; Reversible hydration of carbon dioxide. Required for photosynthesis in cotyledons. Binds salicylic acid. Together with BCA4, involved in the CO(2) signaling pathway which controls gas-exchange between plants and the atmosphere by modulating stomatal development and movements. Promotes water use efficiency. (347 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (16%) [HD]