STRINGSTRING
TPP2 TPP2 PME17 PME17 PSY1 PSY1 SBT6.1 SBT6.1 TPST TPST CLE19 CLE19 PSY1-2 PSY1-2 AMC9 AMC9 RALF23 RALF23 SBT3.5 SBT3.5 SERPIN1 SERPIN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TPP2Tripeptidyl-peptidase 2; Serine protease of the proteasome pathway that may function with the 20S proteasome to degrade oxidized proteins generated by environmental stress; Belongs to the peptidase S8 family. (1380 aa)
PME17Probable pectinesterase/pectinesterase inhibitor 17; Acts in the modification of cell walls via demethylesterification of cell wall pectin; In the C-terminal section; belongs to the pectinesterase family. (511 aa)
PSY1Phytoene synthase, chloroplastic; Catalyzes the reaction from prephytoene diphosphate to phytoene; Belongs to the phytoene/squalene synthase family. (422 aa)
SBT6.1Subtilisin-like protease SBT6.1; Serine protease that catalyzes the first step (site-1 cleavage) in the proteolytic activation of various factors, prior to site-2 cleavage. Part of a regulated intramembrane proteolysis (RIP) cascade. Cleaves BZIP17 and BZIP28 after the Arg-Arg-Ile-Leu (RRIL) motif. May cleave BZIP49 after the RRIL motif. Targets the membrane- associated BZIP17 factor, which functions as a stress sensor and transducer in a signaling pathway that resembles an ER stress response. Following salt stress, BZIP17 is cleaved by SBT6.1 (S1P) and S2P at the C-terminus and the N- [...] (1038 aa)
TPSTProtein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides. (500 aa)
CLE19CLAVATA3/ESR (CLE)-related protein 19; Extracellular signal peptide that regulates cell fate. Represses root apical meristem maintenance. Belongs to the CLV3/ESR signal peptide family. (74 aa)
PSY1-2Tyrosine-sulfated glycopeptide 1; Promotes cellular proliferation and expansion. Induces outward H(+) fluxes in roots ; Belongs to the sulfated-peptide plant hormone family. (75 aa)
AMC9Metacaspase-9 subunit p10; Cysteine protease that cleaves specifically after arginine or lysine residues. Does not cleave caspase-specific substrates. Required for proteolytic processing of GRI. Belongs to the peptidase C14B family. (325 aa)
RALF23Rapid alkalinization factor 23; Cell signaling peptide that may regulate plant stress, growth, and development. Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity). Regulates negatively brassinolide (BL)-mediated signaling pathway (e.g. BL-induced hypocotyl elongation and branching limitation). (138 aa)
SBT3.5Subtilisin-like protease SBT3.5; Serine protease that cleaves the pectin methylesterase 17 (PME17) protein to release the PME17 mature form in the apoplasm. Belongs to the peptidase S8 family. (774 aa)
SERPIN1Serpin-ZX; Inhibits metacaspase-9 (MC9) cysteine protease. Functions through cleavage of its reactive center loop and covalent binding to MC9. Involved in the control of elicitor-stimulated programmed cell death (PCD). During infection by the necrotrophic fungal pathogen Botrytis cinerea, functions to protect cells by limiting the PCD- promoting protease RD21A activity that is released from the ER body or vacuole to the cytoplasm. Involved in the control of water stress-induced cell death by limiting the pro-death protease RD21A activity that is released from the vacuole to the cytoplasm. (391 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (32%) [HD]