STRINGSTRING
LOS1 LOS1 CRK6 CRK6 RLP13 RLP13 RLP15 RLP15 ABA2 ABA2 LAC17 LAC17 PME61 PME61 LAC12 LAC12 COBL4 COBL4 HSP70-4 HSP70-4 RLP1 RLP1 RLP53 RLP53 EXPB1 EXPB1 FAR1-2 FAR1-2 ENDO1 ENDO1 A0A1I9LS88 A0A1I9LS88 EFR EFR RLP14 RLP14 F20B24.8 F20B24.8 RLP45 RLP45 RLP56 RLP56 F8A5.12 F8A5.12 EXLB1 EXLB1 NAC029 NAC029 IRX12 IRX12 TUFA TUFA PGL3 PGL3 SD31 SD31 UBC7 UBC7 LAC10 LAC10 CRK10 CRK10 FLA12 FLA12 FLA11 FLA11 PME53 PME53 K19E20.1 K19E20.1 F21D18.17 F21D18.17 ELIP2 ELIP2 RLP38 RLP38 PME51 PME51 EGC1 EGC1 EXPB3 EXPB3 PME34 PME34 LAC5 LAC5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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LOS1Elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity). Involved in cold responses leading to freezing tolerance via the induction of cold- responsive genes. Belongs to the [...] (843 aa)
CRK6Cysteine-rich receptor-like protein kinase 6. (674 aa)
RLP13Receptor-like protein 13. (1068 aa)
RLP15Receptor-like protein 15. (965 aa)
ABA2Xanthoxin dehydrogenase; Involved in the biosynthesis of abscisic acid. (285 aa)
LAC17Laccase-17; Lignin degradation and detoxification of lignin-derived products. (577 aa)
PME61Probable pectinesterase/pectinesterase inhibitor 61; Acts in the modification of cell walls via demethylesterification of cell wall pectin; In the C-terminal section; belongs to the pectinesterase family. (587 aa)
LAC12Laccase-12; Lignin degradation and detoxification of lignin-derived products. (565 aa)
COBL4COBRA-like protein 4; Belongs to the COBRA family. (431 aa)
HSP70-4Heat shock 70 kDa protein 4; In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions (Probable). ATP-dependent molecular chaperone that assists folding of unfolded or misfolded proteins under stress conditions. Mediates plastid precursor degradation to prevent cytosolic precursor accumulation, together with the E3 ubiquitin-protein ligase CHIP. Recognizes specific sequence motifs in tr [...] (650 aa)
RLP1Receptor-like protein 1; Involved in plant defense. Confers resistance to the bacterial pathogen Xanthomonas through recognition of the microbe- associated molecular pattern (MAMP) eMax. Functionality seems to depend on the presence of the receptor kinase SOBIR1 as an adapter protein. Belongs to the RLP family. (1077 aa)
RLP53Receptor-like protein 53; Belongs to the RLP family. (957 aa)
EXPB1Expansin-B1; May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found (By similarity). Belongs to the expansin family. Expansin B subfamily. (271 aa)
FAR1-2Protein FAR-RED IMPAIRED RESPONSE 1; Transcription activator that recognizes and binds to the DNA consensus sequence 5'-CACGCGC-3'. Activates the expression of FHY1 and FHL involved in light responses. Positive regulator of chlorophyll biosynthesis via the activation of HEMB1 gene expression. (827 aa)
ENDO1Endonuclease 1; Endonuclease that can use RNA, single-stranded and double- stranded DNA as substrates. Hydrolyzes single- stranded DNA and RNA without apparent specificity for bases during senescence. Endonuclease that recognizes and cleaves all types of mismatches with high efficiency, including heteroduplex double-stranded DNA. Maybe involved in programmed cell death (PCD) and senescence. (305 aa)
A0A1I9LS88Pectin lyase-like superfamily protein. (589 aa)
EFRLRR receptor-like serine/threonine-protein kinase EFR; Constitutes the pattern-recognition receptor (PPR) that determines the specific perception of elongation factor Tu (EF-Tu), a potent elicitor of the defense response to pathogen-associated molecular patterns (PAMPs). Reduces transformation by Rhizobium radiobacter probably by inducing plant defense during the interaction. Binding to the effector AvrPto1 from P.syringae blocks the downstream plant immune response while interaction with hopD2 decreases the phosphorylation level of EFR upon elf18 treatment. Specific endoplasmic reticu [...] (1031 aa)
RLP14Receptor-like protein 14. (976 aa)
F20B24.8Pectin lyase-like superfamily protein. (532 aa)
RLP45Receptor-like protein 45; Belongs to the RLP family. (948 aa)
RLP56Receptor-like protein 56; Belongs to the RLP family. (947 aa)
F8A5.12Pectin lyase-like superfamily protein. (540 aa)
EXLB1Expansin-like B1. (250 aa)
NAC029NAC transcription factor 29; Transcription activator that binds to, and transactivates the promoter of the abscisic aldehyde oxidase AAO3. Promotes chlorophyll degradation in leaves by enhancing transcription of AAO3, which leads to increased levels of the senescence-inducing hormone abscisic acid (ABA). Involved in the control of dehydration in senescing leaves. Binds to the DNA sequence 5'-CACGTAAGT-3' of SAG113 promoter. SAG113 acts as negative regulator of ABA signaling for stomatal closure in leaves, and controls water loss during leaf senescence. Transcription factor of the NAC f [...] (268 aa)
IRX12Laccase-4; Lignin degradation and detoxification of lignin-derived products (By similarity). Required for secondary xylem cell wall lignification; Belongs to the multicopper oxidase family. (558 aa)
TUFAElongation factor Tu, chloroplastic; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (476 aa)
PGL3Polygalacturonase 1 beta-like protein 3; Involved in cell size determination. May serve as a chaperone for expansins through the secretory pathway. (626 aa)
SD31G-type lectin S-receptor-like serine/threonine-protein kinase SD3-1. (764 aa)
UBC7Ubiquitin-conjugating enzyme E2 7; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Involved in the formation of multiubiquitin chains. Signal the protein for selective degradation. (166 aa)
LAC10Laccase-10; Lignin degradation and detoxification of lignin-derived products. (558 aa)
CRK10Cysteine-rich receptor-like protein kinase 10; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CRK subfamily. (669 aa)
FLA12Fasciclin-like arabinogalactan protein 12; May be a cell surface adhesion protein; Belongs to the fasciclin-like AGP family. (249 aa)
FLA11Fasciclin-like arabinogalactan protein 11; May be a cell surface adhesion protein. (246 aa)
PME53Probable pectinesterase 53; Acts in the modification of cell walls via demethylesterification of cell wall pectin; Belongs to the pectinesterase family. (383 aa)
K19E20.1Probable pectate lyase 20. (417 aa)
F21D18.17Polygalacturonase At1g48100; Polygalacturonase not involved in the final stages of pod shatter; Belongs to the glycosyl hydrolase 28 family. (475 aa)
ELIP2Early light-induced protein 2, chloroplastic; Probably involved in the integration of pigments into the mature light-harvesting pigment-protein complexes. Light-harvesting chlorophyll (LHC) a/b-binding protein required to ensure a high rate of chlorophyll accumulation during deetiolation in continuous high light. Involved in seed germination. May fulfill a photoprotective functions. Prevents excess accumulation of free chlorophyll by inhibiting the entire chlorophyll biosynthesis pathway (e.g. 5-aminolevulinate synthesis and Mg-protoporphyrin IX chelatase activity), and hence prevent p [...] (193 aa)
RLP38Receptor-like protein 38. (784 aa)
PME51Probable pectinesterase/pectinesterase inhibitor 51; Acts in the modification of cell walls via demethylesterification of cell wall pectin; In the C-terminal section; belongs to the pectinesterase family. (551 aa)
EGC1Putative EG45-like domain containing protein 1; Might have a systemic role in water and solute homeostasis. (123 aa)
EXPB3Expansin-B3; May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found (By similarity). (264 aa)
PME34Probable pectinesterase/pectinesterase inhibitor 34; Acts in the modification of cell walls via demethylesterification of cell wall pectin; In the N-terminal section; belongs to the PMEI family. (598 aa)
LAC5Laccase-5; Lignin degradation and detoxification of lignin-derived products. (580 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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