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RPS1 RPS1 RABB1B RABB1B atp9 atp9 ND4L ND4L ND4 ND4 RPL2 RPL2 RPL10 RPL10 rps12-A rps12-A CCMC CCMC RPS12 RPS12 ND3 ND3 ATPA ATPA RPS7 RPS7 ND1 ND1 CCMB CCMB COX2 COX2 CCMFC CCMFC NAD7 NAD7 RPS13-2 RPS13-2 NAD9 NAD9 RPL16 RPL16 SDH4 SDH4 psbD psbD accD accD psaA psaA psaB psaB clpP1 clpP1 petB petB psbB psbB psbC psbC ycf2-A ycf2-A rpl2-A rpl2-A rpl16 rpl16 rps8 rps8 rps14 rps14 rps19 rps19 ATP9 ATP9 ND6 ND6 COX1 COX1 rps7-A rps7-A psbA psbA rps14-2 rps14-2 atp6 atp6 nad1 nad1 nad5 nad5 nad2 nad2 cox2 cox2 ccmB ccmB rps7 rps7 nad9 nad9 ccmFC ccmFC nad6 nad6 nad4 nad4 mttB mttB rpl2 rpl2 nad3 nad3 ccmC ccmC rps12 rps12 nad7 nad7 matR matR nad4L nad4L atp4 atp4 ABCI5 ABCI5 ND2 ND2 RPL6 RPL6 atpE atpE atpB atpB ND5 ND5 RPS19 RPS19 RPS13 RPS13 RPL8A RPL8A rpoB rpoB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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RPS130S ribosomal protein S1, chloroplastic; Required for optimal plastid performance in terms of photosynthesis and growth. Required for the translation of plastid mRNAs. Involved in cellular heat stress response and required for heat tolerance. Required for transcriptional activation of HSFA2 and its target genes in response to heat stress. Plays a critical role in biosynthesis of thylakoid membrane proteins encoded by chloroplast genes. (416 aa)
RABB1BRas-related protein RABB1b; Intracellular vesicle trafficking and protein transport. (211 aa)
atp9ATP synthase subunit 9, mitochondrial; Belongs to the ATPase C chain family. (85 aa)
ND4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (100 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (495 aa)
RPL260S ribosomal protein L2, mitochondrial; Belongs to the universal ribosomal protein uL2 family. (349 aa)
RPL1050S ribosomal protein L10, chloroplastic; This protein binds directly to 23S ribosomal RNA. (220 aa)
rps12-A30S ribosomal protein S12, chloroplastic; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits (By similarity). (123 aa)
CCMCPutative cytochrome c biosynthesis ccmC-like mitochondrial protein; May be involved in the export of heme to the mitochondrion for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (232 aa)
RPS12Ribosomal protein S12, mitochondrial; Protein S12 is involved in the translation initiation step; Belongs to the universal ribosomal protein uS12 family. (125 aa)
ND3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (119 aa)
ATPAATP synthase subunit alpha, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the [...] (507 aa)
RPS7Ribosomal protein S7, mitochondrial; One of the primary rRNA binding proteins, it binds directly to 18S rRNA where it nucleates assembly of the head domain of the small subunit; Belongs to the universal ribosomal protein uS7 family. (148 aa)
ND1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (325 aa)
CCMBPutative cytochrome c biogenesis ccmB-like mitochondrial protein; May be involved in the export of heme to the mitochondrion for the biogenesis of c-type cytochromes. (206 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (260 aa)
CCMFCCytochrome c biogenesis CcmF C-terminal-like mitochondrial protein; Forms a complex with CCMFN1, CCMFN2 and CCMH that performs the assembly of heme with c-type apocytochromes in mitochondria. Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family. (442 aa)
NAD7NADH dehydrogenase [ubiquinone] iron-sulfur protein 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). Component of the iron-sulfur (IP) fragment of the enzyme. (394 aa)
RPS13-2Small ribosomal subunit protein S13, mitochondrial; Located at the top of the head of the small subunit, it contacts several helices of the 18S rRNA. (154 aa)
NAD9NADH dehydrogenase [ubiquinone] iron-sulfur protein 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (190 aa)
RPL1660S ribosomal protein L16, mitochondrial; Belongs to the universal ribosomal protein uL16 family. (179 aa)
SDH4Succinate dehydrogenase subunit 4, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (151 aa)
psbDPhotosystem II D2 protein; Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors. D2 is needed for assembly of a stable PSII complex. (353 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (488 aa)
psaAPhotosystem I P700 chlorophyll a apoprotein A1; PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin. (750 aa)
psaBPhotosystem I P700 chlorophyll a apoprotein A2; PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin. (734 aa)
clpP1Chloroplastic ATP-dependent Clp protease proteolytic subunit 1; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. (196 aa)
petBCytochrome b6; Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. (215 aa)
psbBPhotosystem II CP47 reaction center protein; One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light- induced photochemical processes of PSII. PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation; Belongs to the PsbB/PsbC family. PsbB subfamily. (508 aa)
psbCPhotosystem II CP43 reaction center protein; One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light- induced photochemical processes of PSII. PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation; Belongs to the PsbB/PsbC family. PsbC subfamily. (473 aa)
ycf2-AProtein Ycf2; Probable ATPase of unknown function. Its presence in a non- photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis; Belongs to the Ycf2 family. (2294 aa)
rpl2-A50S ribosomal protein L2, chloroplastic; Belongs to the universal ribosomal protein uL2 family. (274 aa)
rpl1650S ribosomal protein L16, chloroplastic; Belongs to the universal ribosomal protein uL16 family. (135 aa)
rps830S ribosomal protein S8, chloroplastic; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit. (134 aa)
rps1430S ribosomal protein S14, chloroplastic; Binds 16S rRNA, required for the assembly of 30S particles. Belongs to the universal ribosomal protein uS14 family. (100 aa)
rps1930S ribosomal protein S19, chloroplastic; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
ATP9ATP synthase subunit 9, mitochondrial; This protein is one of the chains of the nonenzymatic membrane component (F0) of mitochondrial ATPase. (85 aa)
ND6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (205 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (527 aa)
rps7-A30S ribosomal protein S7, chloroplastic; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. (155 aa)
psbAPhotosystem II protein D1; Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors. (353 aa)
rps14-2Mitochondrial ribosomal protein S14. (164 aa)
atp6ATP synthase subunit a. (385 aa)
nad1NADH-ubiquinone oxidoreductase chain 1; Belongs to the complex I subunit 1 family. (325 aa)
nad5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (669 aa)
nad2NADH dehydrogenase subunit 2. (488 aa)
cox2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (260 aa)
ccmBCytochrome c biogenesis B. (206 aa)
rps7Ribosomal protein S7. (148 aa)
nad9NADH dehydrogenase subunit 9; Belongs to the complex I 30 kDa subunit family. (190 aa)
ccmFCCytochrome c biogenesis FC. (442 aa)
nad6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (205 aa)
nad4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (495 aa)
mttBTransport membrane protein. (280 aa)
rpl2Ribosomal protein L2. (349 aa)
nad3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (118 aa)
ccmCPutative cytochrome c biosynthesis ccmC-like mitochondrial protein; May be involved in the export of heme to the mitochondrion for the biogenesis of c-type cytochromes. Belongs to the CcmC/CycZ/HelC family. (256 aa)
rps12Ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family. (125 aa)
nad7NADH dehydrogenase subunit 7; Belongs to the complex I 49 kDa subunit family. (394 aa)
matRMaturase. (656 aa)
nad4LNADH dehydrogenase subunit 4L. (100 aa)
atp4ATPase subunit 4. (192 aa)
ABCI5Putative cytochrome c biosynthesis ccmC-like mitochondrial protein; May be involved in the export of heme to the mitochondrion for the biogenesis of c-type cytochromes. Belongs to the CcmC/CycZ/HelC family. (256 aa)
ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (499 aa)
RPL650S ribosomal protein L6, chloroplastic; This protein binds directly to 23S ribosomal RNA and is located at the aminoacyl-tRNA binding site of the peptidyltransferase center. (223 aa)
atpEATP synthase epsilon chain, chloroplastic; Produces ATP from ADP in the presence of a proton gradient across the membrane. (132 aa)
atpBATP synthase subunit beta, chloroplastic; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (498 aa)
ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (669 aa)
RPS1940S ribosomal protein S19, mitochondrial; The RNA-binding domain found in RPS19 may functionally replaces the missing mitochondrial RPS13; Belongs to the universal ribosomal protein uS19 family. (212 aa)
RPS1330S ribosomal protein S13, chloroplastic; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; Belongs to the universal ribosomal protein uS13 family. (169 aa)
RPL8A60S ribosomal protein L8-1. (258 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1072 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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