STRINGSTRING
APX6 APX6 CYT1 CYT1 CLPD CLPD APX1 APX1 APX3 APX3 APXS APXS APXT APXT MES10 MES10 GME GME DHAR2 DHAR2 MDAR3 MDAR3 SAG13 SAG13
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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APX6Putative L-ascorbate peroxidase 6; Plays a key role in hydrogen peroxide removal. (329 aa)
CYT1Mannose-1-phosphate guanylyltransferase 1; Catalyzes a reaction of the Smirnoff-Wheeler pathway, the major route to ascorbate biosynthesis in plants. Plays an essential role in plant growth and development and cell-wall architecture. Provides GDP-mannose, used for cell wall carbohydrate biosynthesis, protein N-glycosylation, as well as for the biosynthesis of the antioxidant ascorbate. (361 aa)
CLPDChaperone protein ClpD, chloroplastic; Molecular chaperone that interact with a ClpP-like protease involved in degradation of denatured proteins in the chloroplast. The ATPase activity of CLPD is stimulated by CLPT1. Has no ADPase activity. Interacts with transit peptides with a positional preference. Localization of the signal sequence at the N-terminal end of a protein seems mandatory for interaction to take place ; Belongs to the ClpA/ClpB family. ClpD subfamily. (945 aa)
APX1L-ascorbate peroxidase 1, cytosolic; Plays a key role in hydrogen peroxide removal. Constitutes a central component of the reactive oxygen gene network. (250 aa)
APX3L-ascorbate peroxidase 3; Plays a key role in hydrogen peroxide removal. (287 aa)
APXSL-ascorbate peroxidase S, chloroplastic/mitochondrial; Plays a key role in hydrogen peroxide removal; Belongs to the peroxidase family. Ascorbate peroxidase subfamily. (372 aa)
APXTL-ascorbate peroxidase T, chloroplastic; Plays a key role in hydrogen peroxide removal; Belongs to the peroxidase family. Ascorbate peroxidase subfamily. (426 aa)
MES10Methylesterase 10; Methylesterase shown to have methyl jasmonate (MeJA) esterase activity in vitro. (275 aa)
GMEGDP-mannose 3,5-epimerase; Catalyzes a reversible epimerization of GDP-D-mannose that precedes the committed step in the biosynthesis of vitamin C (L- ascorbate), resulting in the hydrolysis of the highly energetic glycosyl-pyrophosphoryl linkage. Able to catalyze 2 distinct epimerization reactions and can release both GDP-L-galactose and GDP-L- gulose from GDP-mannose. (377 aa)
DHAR2Glutathione S-transferase DHAR2; Displays a dual function. As a soluble protein, exhibits glutathione-dependent thiol transferase and dehydroascorbate (DHA) reductase activities. Exhibits glutathione-dependent thiol transferase and dehydroascorbate (DHA) reductase activities. Key component of the ascorbate recycling system. Involved in the redox homeostasis, especially in scavenging of ROS under oxidative stresses. Plays a role in ozone tolerance; Belongs to the GST superfamily. DHAR family. (213 aa)
MDAR3Monodehydroascorbate reductase 3; Catalyzes the conversion of monodehydroascorbate to ascorbate, oxidizing NADH in the process. Required for producing sufficient ascorbate to maintain the interaction between Piriformospora indica and Arabidopsis in a mutualistic state. (441 aa)
SAG13Senescence-associated protein 13; Unspecific reductase providing both diastereomeric alcohols from the prochiral ketones. Active on cyclic monoterpenes and small flexible lipophilic carbonyls. No activity with tropinone, nitrogen- containing tropinone analogs, tropine or pseudotropine as substrate. (269 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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