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BAH1 BAH1 PHT1-8 PHT1-8 PHT1-4 PHT1-4 PHR1 PHR1 PHL2 PHL2 UBC24 UBC24 SPX1 SPX1 PHL3 PHL3 PHL1 PHL1 SIZ1 SIZ1 PHT1-7 PHT1-7 MYB101 MYB101 SPX2 SPX2 EXPB3 EXPB3 PHT1-9 PHT1-9 LSM7 LSM7 EXPB1 EXPB1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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BAH1E3 ubiquitin-protein ligase BAH1; Mediates E2-dependent protein ubiquitination. Plays a role in salicylic acid-mediated negative feedback regulation of salicylic acid (SA) accumulation. May be involved in the overall regulation of SA, benzoic acid and phenylpropanoid biosynthesis. Controls the adaptability to nitrogen limitation by channeling the phenylpropanoid metabolic flux to the induced anthocyanin synthesis. (335 aa)
PHT1-8Probable inorganic phosphate transporter 1-8; High-affinity transporter for external inorganic phosphate. (534 aa)
PHT1-4Inorganic phosphate transporter 1-4; High-affinity transporter for external inorganic phosphate. Acts as a H(+):phosphate symporter in both low- and high-Pi conditions. Confers sensitivity to arsenate. (534 aa)
PHR1Protein PHOSPHATE STARVATION RESPONSE 1; Transcription factor involved in phosphate starvation signaling. Binds as a dimer to P1BS, an imperfect palindromic sequence 5'-GNATATNC-3', to promote the expression of inorganic phosphate (Pi) starvation- responsive genes. SPX1 is a competitive inhibitor of this DNA-binding. PHR1 binding to its targets is low Pi-dependent. Regulates the expression of miR399. Regulates the expression of IPS1 (At3g09922), a non-coding RNA that mimics the target of miR399 to block the cleavage of PHO2 under Pi-deficient conditions. Regulates lipid remodeling and [...] (409 aa)
PHL2Protein PHR1-LIKE 2; Transcriptional activator. Acts redundantly with PHR1 as a key component of the central regulatory system controlling transcriptional responses to Pi starvation. Binds in a sequence-specific manner to phosphate starvation-regulated promoters. (295 aa)
UBC24Probable ubiquitin-conjugating enzyme E2 24; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (By similarity). Mediates PHO1 degradation through multivesicular body-mediated vacuolar proteolysis in response to inorganic phosphate (Pi) availability. Negatively regulates the protein abundance of PHF1 and PHT1s under Pi- sufficient conditions by facilitating the degradation of PHT1 proteins at the endomembrane. (907 aa)
SPX1SPX domain-containing protein 1; Plays a positive role in plant adaptation to phosphate starvation. Inhibits PHR1 DNA-binding activity in a Pi-dependent manner. (256 aa)
PHL3Protein PHR1-LIKE 3; Transcriptional activator. Probable component of the central regulatory system controlling transcriptional responses to Pi starvation. Binds in a sequence- specific manner to phosphate starvation-regulated promoters. Required for female gametophyte development and function. (292 aa)
PHL1Protein PHR1-LIKE 1; Transcription factor acting as central integrator of phosphate starvation responses. Regulates FER1 expression upon phosphate starvation, linking iron and phosphate homeostasis ; Belongs to the MYB-CC family. (413 aa)
SIZ1E3 SUMO-protein ligase SIZ1; E3 SUMO protein ligase involved in regulation processes. Mediates SUMO/ attachment to PHR1, a MYB transcriptional activator controlling the phosphate deficiency responses. Functions as an upstream negative regulator of salicylic acid (SA) accumulation and subsequent SA-mediated systemic acquired resistance (SAR) signaling. Probably not involved in jasmonic acid (JA)-mediated defense response. Participates in abiotic stress-induced sumoylation. Controls heat shock-induced SUMO1 and SUMO2 conjugation and facilitates basal thermotolerance. Involved in freezing [...] (884 aa)
PHT1-7Probable inorganic phosphate transporter 1-7; High-affinity transporter for external inorganic phosphate. (535 aa)
MYB101Transcription factor MYB101; Transcription activator. Binds to 5'-CAACTGTC-3' and/or 5'-TAACAAA-3' motif in target gene promoter (e.g. alpha-amylase) to promote their expression. Positive regulator of abscisic acid (ABA) responses leading to growth arrest during seed germination. Promotes the expression of aleurone-related genes (e.g. CP1, CP, GASA1, BXL1 and BXL2) in seeds. Together with MYB33 and MYB65, promotes the programmed cell death (PCD) leading to vacuolation of protein storage vacuoles (PSVs) in the aleurone layers during seed germination. Maybe involved in the regulation of [...] (490 aa)
SPX2SPX domain-containing protein 2; May inhibit PHR1 DNA-binding activity in a Pi-dependent manner. (287 aa)
EXPB3Expansin-B3; May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found (By similarity). (264 aa)
PHT1-9Probable inorganic phosphate transporter 1-9; High-affinity transporter for external inorganic phosphate. Belongs to the major facilitator superfamily. phosphate:H(+) symporter (TC 2.A.1.9) family. (532 aa)
LSM7Sm-like protein LSM7; Component of LSM protein complexes, which are involved in RNA processing. Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by promoting decapping and leading to accurate 5'-3' mRNA decay. The cytoplasmic LSM1-LSM7 complex regulates developmental gene expression by the decapping of specific development- related transcripts. Component of the nuclear LSM2-LSM8 complex which is involved splicing nuclear mRNAs. LSM2-LSM8 binds directly to the U6 small nuclear RNAs (snRNAs) and is essential for accurate splicing of selected developmen [...] (99 aa)
EXPB1Expansin-B1; May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found (By similarity). Belongs to the expansin family. Expansin B subfamily. (271 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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