STRINGSTRING
DRP3A DRP3A ELM1 ELM1 FIS1B FIS1B ACT8 ACT8 UBP27 UBP27 PMD1 PMD1 FIS1A FIS1A PMD2 PMD2 ELM2 ELM2 MEA MEA ARC5 ARC5 DRP3B DRP3B MBL20.6 MBL20.6 Dl4805W Dl4805W
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DRP3ADynamin-related protein 3A; Involved in the control of mitochondrial and peroxisomal division and morphology. In association with PEX11C, PEX11D, PEX11E and FIS1B, is involved in cell cycle-associated constitutive self- replication of preexisting peroxisomes. Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (808 aa)
ELM1Mitochondrial fission protein ELM1; Plant-specific factor involved in mitochondria fission. Is required for the correct localization of DRP3A from the cytosol to mitochondrial fission sites. Does not seem to be required for peroxisomal division. (427 aa)
FIS1BMitochondrial fission 1 protein B; Component of the peroxisomal and mitochondrial division machineries. Plays a role in promoting the fission of mitochondria and peroxisomes. In association with PEX11C, PEX11D, PEX11E and DRP3A, is involved in cell cycle-associated constitutive self-replication of preexisting peroxisomes. (167 aa)
ACT8Actin-8; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the vegetative actins. (377 aa)
UBP27Ubiquitin carboxyl-terminal hydrolase 27; Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity). (494 aa)
PMD1Peroxisomal and mitochondrial division factor 1; Involved in morphogenesis and proliferation of peroxisomes and mitochondria, independently from the previously defined pathway controlled by the FIS1-DRP3 complex. (318 aa)
FIS1AMitochondrial fission 1 protein A; Component of the peroxisomal and mitochondrial division machineries. Plays a role in promoting the fission of mitochondria and peroxisomes; Belongs to the FIS1 family. (170 aa)
PMD2Peroxisomal and mitochondrial division factor 2; Involved in morphogenesis and proliferation of mitochondria. Does not act redundantly with PMD1. Is not involved in peroxisomal proliferation. (323 aa)
ELM2ELM2 domain-containing protein. (434 aa)
MEAHistone-lysine N-methyltransferase MEDEA; Polycomb group (PcG) protein. Catalytic subunit of some PcG multiprotein complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target genes. Required to prevent the proliferation of the central cell of the female gametophyte by repressing target genes before fertilization. After fertilization, it probably also regulates the embryo and endosperm proliferation and anteroposterior organization during seed development. PcG proteins act by forming multiprotein complexes, which are required to maintai [...] (689 aa)
ARC5Dynamin-like protein ARC5; Probable GTPase component of both plastid and peroxisme division machinery. Required for the last steps of plastid division specifically in mesophyll-cell, when the narrow isthmus breaks, facilitating the separation of the daughter plastids. Necessary for peroxisome activities. Seems to influence stromule (stroma-filled tubular extensions of the plastid envelope membrane) length and frequency. Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (777 aa)
DRP3BDynamin-related protein 3B; Involved in the control of mitochondrial and peroxisomal division and morphology. (780 aa)
MBL20.6Fission ELM1-like protein (DUF1022). (404 aa)
Dl4805WDynamin. (294 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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