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CCT2 CCT2 MBK20.7 MBK20.7 PLDBETA2 PLDBETA2 MGD1 MGD1 MGD2 MGD2 FAD7 FAD7 FAD2 FAD2 FAD8 FAD8 FAD3 FAD3 ACBP6 ACBP6 PLDALPHA1 PLDALPHA1 ATS1 ATS1 WRI1 WRI1 ACBP5 ACBP5 DGD2 DGD2 WSD1 WSD1 DGAT3 DGAT3 LACS3 LACS3 BZIP8 BZIP8 PDAT1 PDAT1 LPAT5 LPAT5 GPAT7 GPAT7 TGD2 TGD2 DGL DGL DGD1 DGD1 MGD3 MGD3 FATB FATB LPP2 LPP2 LPP1 LPP1 CCT1-2 CCT1-2
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second shell of interactors
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CCT2Choline-phosphate cytidylyltransferase 2; Plays an important role in the biosynthesis of the phospholipid phosphatidylcholine. Catalyzes the formation of CDP- choline; Belongs to the cytidylyltransferase family. (304 aa)
MBK20.7Protein RFT1 homolog; May be involved in N-linked oligosaccharide assembly. Belongs to the RFT1 family. (611 aa)
PLDBETA2Phospholipase D beta 2; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Plays an important role in various cellular processes, including phytohormone action, vesicular trafficking, secretion, cytoskeletal arrangement, meiosis, tumor promotion, pathogenesis, membrane deterioration and senescence. Can use phosphatidylserine or N- acylphosphatidylethanolamine as substrates; Belongs to the phospholipase D family. C2-PLD subfamily. (927 aa)
MGD1Monogalactosyldiacylglycerol synthase 1, chloroplastic; Involved in the synthesis of the major structural component of photosynthetic membranes. Required for proper thylakoid membrane biogenesis. Does not discriminate between prokaryotic (18:1/16:0) or eukaryotic (18:2/18:2) 1,2-diacylglycerol species, but operates with some preference for the prokaryotic one. Belongs to the glycosyltransferase 28 family. (533 aa)
MGD2Monogalactosyldiacylglycerol synthase 2, chloroplastic; Involved in the synthesis of the major structural component of photosynthetic membranes and in the chloroplast envelope biogenesis. Can use both prokaryotic (18:1/16:0) or eukaryotic (18:2/18:2) 1,2- diacylglycerol species, but operates with some preference for the eukaryotic one; Belongs to the glycosyltransferase 28 family. (468 aa)
FAD7Sn-2 acyl-lipid omega-3 desaturase (ferredoxin), chloroplastic; Chloroplast omega-3 fatty acid desaturase introduces the third double bond in the biosynthesis of 16:3 and 18:3 fatty acids, important constituents of plant membranes. It is thought to use ferredoxin as an electron donor and to act on fatty acids esterified to galactolipids, sulfolipids and phosphatidylglycerol. (446 aa)
FAD2Delta(12)-fatty-acid desaturase; ER (microsomal) omega-6 fatty acid desaturase introduces the second double bond in the biosynthesis of 18:3 fatty acids, important constituents of plant membranes. Delta(12)-desaturase with regioselectivity determined by the double bond (delta(9) position) and carboxyl group of the substrate. Can use both 16:1 and 18:1 fatty acids as substrates. It is thought to use cytochrome b5 as an electron donor and to act on fatty acids esterified to phosphatidylcholine (PC) and, possibly, other phospholipids. Very low constitutive hydroxylation activity. Required [...] (383 aa)
FAD8Temperature-sensitive sn-2 acyl-lipid omega-3 desaturase (ferredoxin), chloroplastic; Chloroplast omega-3 fatty acid desaturase introduces the third double bond in the biosynthesis of 16:3 and 18:3 fatty acids, important constituents of plant membranes. It is thought to use ferredoxin as an electron donor and to act on fatty acids esterified to galactolipids, sulfolipids and phosphatidylglycerol. (435 aa)
FAD3Acyl-lipid omega-3 desaturase (cytochrome b5), endoplasmic reticulum; Microsomal (ER) omega-3 fatty acid desaturase introduces the third double bond in the biosynthesis of 18:3 fatty acids, important constituents of plant membranes. It is thought to use cytochrome b5 as an electron donor and to act on fatty acids esterified to phosphatidylcholine and, possibly, other phospholipids. (386 aa)
ACBP6Acyl-CoA-binding domain-containing protein 6; Binds medium- and long-chain acyl-CoA esters with very high affinity. May function as an intracellular carrier of acyl-CoA esters. Confers resistance to cold and freezing. Interacts with phosphatidylcholine and derivatives, but not phosphatidic acid and lysophosphatidylcholine. May be involved in phospholipid metabolism. Belongs to the ACBP family. (92 aa)
PLDALPHA1Phospholipase D alpha 1; Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Plays an important role in various cellular processes, including phytohormone action and response to stress, characterized by acidification of the cell. Involved in wound induction of jasmonic acid. May be involved in membrane lipid remodeling. Probably involved in freezing tolerance by modulating the cold-responsive genes and accumulation of osmolytes. Can use phosphatidylcholine (PC), phosphatidylethanolamine (PE) and phosphatidylglycerol (PG) as subst [...] (810 aa)
ATS1Glycerol-3-phosphate acyltransferase, chloroplastic; Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate. The enzyme from chilling-resistant plants discriminates against non-fluid palmitic acid and selects oleic acid whereas the enzyme from sensitive plants accepts both fatty acids. This is an oleate-selective acyltransferase. (459 aa)
WRI1Ethylene-responsive transcription factor WRI1; May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Transcriptional activator involved in the activation of a subset of sugar-responsive genes and the control of carbon flow from sucrose import to oil accumulation in developing seeds. Binds to the GCC-box pathogenesis-related promoter element. Promotes sugar uptake and seed oil accumulation by glycolysis. Required for embryo development, seed germination and, indirectly, for seedling establishment. [...] (430 aa)
ACBP5Acyl-CoA-binding domain-containing protein 5; Binds medium- and long-chain acyl-CoA esters with very high affinity. Can interact in vitro with oleoyl-CoA, barely with palmitoyl- CoA, but not with arachidonyl-CoA. May function as an intracellular carrier of acyl-CoA esters (By similarity); Belongs to the ACBP family. (648 aa)
DGD2Digalactosyldiacylglycerol synthase 2, chloroplastic; Involved in the synthesis of diacylglycerol galactolipids that are specifically found in thylakoid membranes. Specific for alpha- glycosidic linkages. During phosphate shortage, involved in the biosynthesis of digalactosyldiacylglycerol (DGDG) which rescues the limitation of phospholipids (Probable); Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. (473 aa)
WSD1O-acyltransferase WSD1; Bifunctional wax ester synthase/diacylglycerol acyltransferase. Involved in cuticular wax biosynthesis. In the N-terminal section; belongs to the long-chain O- acyltransferase family. (481 aa)
DGAT3Diacylglycerol O-acyltransferase 3; Involved in triacylglycerol (TAG) biosynthesis. Catalyzes the acylation of the sn-3 hydroxy group of sn-1,2-diacylglycerol using acyl-CoA. May preferentially use linolenoyl-CoA as substrate and to a lesser extent linoleoyl-CoA. May contribute to the active recycling of linoleate and linolenate into TAG when seed oil breakdown is blocked. (360 aa)
LACS3Long chain acyl-CoA synthetase 3; Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitate, palmitoleate, oleate and linoleate; Belongs to the ATP-dependent AMP-binding enzyme family. (665 aa)
BZIP8Basic leucine zipper 8; Belongs to the bZIP family. (138 aa)
PDAT1Phospholipid:diacylglycerol acyltransferase 1; Triacylglycerol formation by an acyl-CoA independent pathway. The enzyme preferentially transfers acyl groups from the sn-2 position of a phospholipid to diacylglycerol, thus forming an sn-1- lysophospholipid. Involved in epoxy and hydroxy fatty acid accumulation in seeds. Has complementary functions with DAG1 that are essential for triacylglycerol synthesis and normal development of both seeds and pollen. (671 aa)
LPAT5Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 5; May convert lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position (By similarity). Has no activity when expressed in bacteria or yeast. (375 aa)
GPAT7Glycerol-3-phosphate acyltransferase 7; Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. (500 aa)
TGD2Protein TRIGALACTOSYLDIACYLGLYCEROL 2, chloroplastic; Component of a phosphatidic acid/lipid transport complex in the chloroplast envelope. Specifically binds phosphatidic acid (PA). Involved in lipid transfer from the endoplasmic reticulum (ER) to plastids, and necessary for thylakoids formation. (381 aa)
DGLGalactolipase DONGLE, chloroplastic; Sn-1-specific phospholipase that releases free fatty acids from phosphatidylcholine. Has a higher galactolipase activity than phospholipase A1 activity when digalactosyldiacylglycerol (DGDG) is used as substrate. Catalyzes the initial step of jasmonic acid biosynthesis. Required for the biosynthesis of basal-level endogenous jasmonate in vegetative tissues. Regulates leaves growth. Not essential for jasmonate biosynthesis after wounding or upon pathogen infection. (471 aa)
DGD1Digalactosyldiacylglycerol synthase 1, chloroplastic; Involved in the synthesis of diacylglycerol galactolipids that are specifically found in thylakoid membranes. Specific for alpha- glycosidic linkages. Responsible for the final assembly of galactolipids in photosynthetic membranes. Digalactosyldiacylglycerol (DGDG) provides stability to the photosystem I (PSI) complex, especially to the PsaA, PsaB, PsaC, PsaL and PsaH subunits. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. (808 aa)
MGD3Monogalactosyldiacylglycerol synthase 3, chloroplastic; Involved in the synthesis of the major structural component of photosynthetic membranes and in the chloroplast envelope biogenesis. Can use both prokaryotic (18:1/16:0) or eukaryotic (18:2/18:2) 1,2- diacylglycerol species, but operates with some preference for the eukaryotic one. (465 aa)
FATBPalmitoyl-acyl carrier protein thioesterase, chloroplastic; Plays an essential role in chain termination during de novo fatty acid synthesis. Possesses high thioesterase activity for palmitoyl-ACP versus other acyl-ACPs. Substrate preference is 16:0 > 18:1 > 18:0 > 16:1. Plays an essential role in the supply of saturated fatty acids necessary for plant growth and seed development. Contributes to 16:0 production particularly in flowers. May be involved in the synthesis of long chain fatty acid. (412 aa)
LPP2Lipid phosphate phosphatase 2; May play a general 'housekeeping role' in lipid metabolism. Exhibits both diacylglycerol pyrophosphate (DGPP) phosphatase and phosphatidate (PA) phosphatase activities with no preference for either substrate. May play a role downstream of the ABA signaling pathway during seed germination and in stomatal movement in leaves. Belongs to the PA-phosphatase related phosphoesterase family. (290 aa)
LPP1Lipid phosphate phosphatase 1; Plays a general role in cellular responses to stress, may be by attenuating the signal produced by phospholipases. Exhibits both diacylglycerol pyrophosphate (DGPP) phosphatase and phosphatidate (PA) phosphatase activities. Substrate preference is diacylglycerol pyrophosphate > phosphatidate; Belongs to the PA-phosphatase related phosphoesterase family. (327 aa)
CCT1-2Choline-phosphate cytidylyltransferase 1; Plays an important role in the biosynthesis of the phospholipid phosphatidylcholine. Catalyzes the formation of CDP- choline. (332 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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