STRINGSTRING
M3E9.180 M3E9.180 cox2 cox2 RBSK RBSK T28K15.4 T28K15.4 PPDK PPDK UROS UROS SQD1 SQD1 ABCG1 ABCG1 AKHSDH2 AKHSDH2 F24G24.60 F24G24.60 RCA RCA GAPC1 GAPC1 CDKB1-1 CDKB1-1 TBP1 TBP1 TBP2 TBP2 ICL ICL psaA psaA psbC psbC rps16 rps16 COX2 COX2 NPF6.3 NPF6.3 CTR1 CTR1 CDKB1-2 CDKB1-2 SAT3 SAT3 SAT5 SAT5 SAT1 SAT1 GAPCP2 GAPCP2 PPC2 PPC2 ABCC4 ABCC4 ABCA1 ABCA1 PPC3 PPC3 PPC4 PPC4 CDKB2-1 CDKB2-1 CDKB2-2 CDKB2-2 SAT2 SAT2 SAT4 SAT4 LFNR2 LFNR2 PETJ PETJ PKP3 PKP3 CPX2 CPX2 Q94KE3_ARATH Q94KE3_ARATH AUX1 AUX1 F28G11.11 F28G11.11 MBK5.16 MBK5.16 LFNR1 LFNR1 MIO24.3 MIO24.3 PKP2 PKP2 MCD7.8 MCD7.8 MAH20.13 MAH20.13 GAPC2 GAPC2 PKP1 PKP1 T21E18.8 T21E18.8 T21E18.7 T21E18.7 CPX1 CPX1 Q9LU95_ARATH Q9LU95_ARATH TRA2 TRA2 F1I16_220 F1I16_220 F1I16_60 F1I16_60 RFNR1 RFNR1 T16L24.30 T16L24.30 ECR ECR PKP4 PKP4 PPC1 PPC1 RFNR2 RFNR2 AKHSDH1 AKHSDH1 GAPCP1 GAPCP1 PDK PDK T28P16.12 T28P16.12 PAT PAT F1O11.21 F1O11.21 PGR5 PGR5 T11I18.16 T11I18.16 FAS1 FAS1 PSBS PSBS ABCB1 ABCB1 ABCG2 ABCG2
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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experimentally determined
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M3E9.180Probable pyruvate kinase, cytosolic isozyme; Key regulatory enzyme of the glycolytic pathway that catalyzes the final step of glycolysis, converting ADP and phosphoenolpyruvate (PEP) to ATP and pyruvate by essentially irreversible transphosphorylation. (497 aa)
cox2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (260 aa)
RBSKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway (By similarity). Can also use xylose and fructose as carbohydrate substrates with a low efficiency. Can use GTP, and, to a lower extent, CTP and UTP as alternative phosphoryl donors. (379 aa)
T28K15.4Aldolase superfamily protein. (427 aa)
PPDKPyruvate, phosphate dikinase 1, chloroplastic; Formation of phosphoenolpyruvate. May be involved in regulating the flux of carbon into starch and fatty acids of seeds and in the remobilization of nitrogen reserves in senescing leaves. (963 aa)
UROSUroporphyrinogen-III synthase, chloroplastic; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, a precursor of tetrapyrroles such as chlorophyll, heme and phycobilins. (321 aa)
SQD1UDP-sulfoquinovose synthase, chloroplastic; Involved in the biosynthesis of sulfolipids found in thylakoid membranes. Converts UDP-glucose and sulfite to the sulfolipid head group precursor UDP-sulfoquinovose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (477 aa)
ABCG1ABC transporter G family member 1. (740 aa)
AKHSDH2Bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic; In the C-terminal section; belongs to the homoserine dehydrogenase family. (916 aa)
F24G24.60Probable fructokinase-5; May play an important role in maintaining the flux of carbon towards starch formation. (324 aa)
RCARibulose bisphosphate carboxylase/oxygenase activase, chloroplastic; Activation of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase; EC 4.1.1.39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure. (474 aa)
GAPC1Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic; Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3- phospho-D-glyceroyl phosphate. Essential for the maintenance of cellular ATP levels and carbohydrate metabolism. Required for full fertility. Involved in response to oxidative stress by mediating plant responses to abscisic acid (ABA) and water deficits through the activation of PLDDELTA and production of phosphatidic acid (PA), a multifunctional stress signaling lipid in plants. Associates with FBA6 to [...] (338 aa)
CDKB1-1Cyclin-dependent kinase B1-1; May control G2/M (mitosis) phase progression. Plays a role in regulating seedling growth in darkness via regulation of hypocotyl cell elongation and cotyledon cell development. Plays a role in stomatal development. Required to suppress endoreduplication. Together with CDKB1-2, promotes both the last division in the stomatal cell lineage as well as the number of stomata. In collaboration with MYB124 and MYB88, restrict the G1/S transition and chloroplast and nuclear number during stomatal formation, and normally maintain fate and developmental progression t [...] (309 aa)
TBP1TATA-box-binding protein 1; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. (200 aa)
TBP2TATA-box-binding protein 2; General transcription factor (GTF) that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II (By similarity). Interacts with TFIIB1 and is required for activated transcription and possibly basal transcription. May act as GTF of RNA polymerase I- dependent transcription and rRNA synthesis. Forms a ternary complex with PBRP1 and the rDNA promoter region. Be [...] (200 aa)
ICLIsocitrate lyase; Involved in storage lipid mobilization during the growth of higher plant seedling; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. (576 aa)
psaAPhotosystem I P700 chlorophyll a apoprotein A1; PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin. (750 aa)
psbCPhotosystem II CP43 reaction center protein; One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light- induced photochemical processes of PSII. PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation; Belongs to the PsbB/PsbC family. PsbC subfamily. (473 aa)
rps1630S ribosomal protein S16, chloroplastic. (79 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (260 aa)
NPF6.3Protein NRT1/ PTR FAMILY 6.3; Dual affinity nitrate transporter. Involved in proton- dependent nitrate uptake and in the regulation of the nitrate transporter NRT2.1. Acts also as a nitrate sensor that trigger a specific signaling pathway stimulating lateral root growth and seed germination. The uptake activity is not required for sensor function. Displays an auxin transport facilitation inhibited by high nitrate concentration. Required to prevent auxin accumulation in preemerged lateral root primordia and young lateral roots when external nitrate concentration is low or null. May be i [...] (590 aa)
CTR1Serine/threonine-protein kinase CTR1; Acts as a negative regulator in the ethylene response pathway. Phosphorylates the cytosolic C-terminal domain of EIN2, preventing the signaling in the absence of ethylene. (821 aa)
CDKB1-2Cyclin-dependent kinase B1-2; Together with CDKB1-1, promotes both the last division in the stomatal cell lineage as well as the number of stomata. In collaboration with MYB124 and MYB88, restrict the G1/S transition and chloroplast and nuclear number during stomatal formation, and normally maintain fate and developmental progression throughout the stomatal cell lineage. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. (311 aa)
SAT3Serine acetyltransferase 3, mitochondrial; Belongs to the transferase hexapeptide repeat family. (391 aa)
SAT5Serine acetyltransferase 5; Belongs to the transferase hexapeptide repeat family. (312 aa)
SAT1Serine acetyltransferase 1, chloroplastic; May be involved in detoxification process by mediating the production of glutathione. (314 aa)
GAPCP2Glyceraldehyde-3-phosphate dehydrogenase GAPCP2, chloroplastic; Involved in plastidial glycolytic pathway and plays a specific role in glycolytic energy production in non-green plastids and chloroplasts. Essential for breakdown of starch to form sucrose for export to non-photosynthetic tissues, and to generate primary metabolites for anabolic pathways such as fatty acid and amino acid synthesis. Plays an important role in plant development by providing substrates for the phosphorylated pathway of serine biosynthesis in roots. Plays a crucial role in pollen development. Functionally red [...] (420 aa)
PPC2Phosphoenolpyruvate carboxylase 2; Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (963 aa)
ABCC4ABC transporter C family member 4; Involved in the regulation of stomatal aperture. May function as a high-capacity pump for folates. (1516 aa)
ABCA1ABC transporter A family member 1; Belongs to the ABC transporter superfamily. ABCA family. CPR flippase (TC 3.A.1.211) subfamily. (1882 aa)
PPC3Phosphoenolpyruvate carboxylase 3; Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (968 aa)
PPC4Phosphoenolpyruvate carboxylase 4; Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (1032 aa)
CDKB2-1Cyclin-dependent kinase B2-1; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. (313 aa)
CDKB2-2Cyclin-dependent kinase B2-2. (315 aa)
SAT2Serine acetyltransferase 2. (323 aa)
SAT4Serine acetyltransferase 4; Belongs to the transferase hexapeptide repeat family. (355 aa)
LFNR2Ferredoxin--NADP reductase, leaf isozyme 2, chloroplastic; Plays a key role in regulating the relative amounts of cyclic and non-cyclic electron flow to meet the demands of the plant for ATP and reducing power. (369 aa)
PETJCytochrome c6, chloroplastic; Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis. (175 aa)
PKP3Plastidial pyruvate kinase 3, chloroplastic; Required for plastidial pyruvate kinase activity. (571 aa)
CPX2Coproporphyrinogen-III oxidase 2, chloroplastic; Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity). (233 aa)
Q94KE3_ARATHPyruvate kinase; Belongs to the pyruvate kinase family. (527 aa)
AUX1Auxin transporter protein 1; Carrier protein involved in proton-driven auxin influx. Mediates the formation of auxin gradient from developing leaves (site of auxin biosynthesis) to tips by contributing to the loading of auxin in vascular tissues and facilitating acropetal (base to tip) auxin transport within inner tissues of the root apex, and basipetal (tip to base) auxin transport within outer tissues of the root apex. Unloads auxin from the mature phloem to deliver the hormone to the root meristem via the protophloem cell files. Coordinated subcellular localization of AUX1 is regula [...] (485 aa)
F28G11.11Probable fructokinase-6, chloroplastic; May play an important role in maintaining the flux of carbon towards starch formation; Belongs to the carbohydrate kinase PfkB family. (384 aa)
MBK5.16Pyruvate kinase; Belongs to the pyruvate kinase family. (510 aa)
LFNR1Ferredoxin--NADP reductase, leaf isozyme 1, chloroplastic; Plays a key role in regulating the relative amounts of cyclic and non-cyclic electron flow to meet the demands of the plant for ATP and reducing power; Belongs to the ferredoxin--NADP reductase type 1 family. (360 aa)
MIO24.3Probable fructokinase-7; May play an important role in maintaining the flux of carbon towards starch formation. (343 aa)
PKP2Plastidial pyruvate kinase 2; Required for plastidial pyruvate kinase activity. Involved in seed oil accumulation, embryo development and seed storage compounds mobilization upon germination. (579 aa)
MCD7.8Pyruvate kinase; Belongs to the pyruvate kinase family. (498 aa)
MAH20.13Pyruvate kinase; Belongs to the pyruvate kinase family. (510 aa)
GAPC2Glyceraldehyde-3-phosphate dehydrogenase GAPC2, cytosolic; Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3- phospho-D-glyceroyl phosphate. Essential for the maintenance of cellular ATP levels and carbohydrate metabolism (By similarity). Binds DNA in vitro. (338 aa)
PKP1Plastidial pyruvate kinase 1, chloroplastic; Required for plastidial pyruvate kinase activity. Involved in seed oil accumulation, embryo development and seed storage compounds mobilization upon germination. (596 aa)
T21E18.8Probable fructokinase-2; May play an important role in maintaining the flux of carbon towards starch formation. (329 aa)
T21E18.7Probable fructokinase-3; May play an important role in maintaining the flux of carbon towards starch formation. (345 aa)
CPX1Coproporphyrinogen-III oxidase 1, chloroplastic; Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III; Belongs to the aerobic coproporphyrinogen-III oxidase family. (386 aa)
Q9LU95_ARATHPyruvate kinase; Belongs to the pyruvate kinase family. (497 aa)
TRA2Aldolase-type TIM barrel family protein. (438 aa)
F1I16_220Pyruvate kinase; Belongs to the pyruvate kinase family. (492 aa)
F1I16_60Pyruvate kinase; Belongs to the pyruvate kinase family. (510 aa)
RFNR1Ferredoxin--NADP reductase, root isozyme 1, chloroplastic; Maintains the supply of reduced ferredoxin under non- photosynthetic conditions. (378 aa)
T16L24.30Probable fructokinase-4; May play an important role in maintaining the flux of carbon towards starch formation. (326 aa)
ECRVery-long-chain enoyl-CoA reductase; Catalyzes the last of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme reduces the trans-2,3-enoyl-CoA fatty acid intermediate to an acyl-CoA that can be further elongated by entering a new cycle of elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (310 aa)
PKP4Plastidial pyruvate kinase 4, chloroplastic. (710 aa)
PPC1Phosphoenolpyruvate carboxylase 1; Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Contributes probably to the adaptation to inorganic phosphate (Pi) deprivation; Belongs to the PEPCase type 1 family. (967 aa)
RFNR2Ferredoxin--NADP reductase, root isozyme 2, chloroplastic; Maintains the supply of reduced ferredoxin under non- photosynthetic conditions. (382 aa)
AKHSDH1Bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic; In the N-terminal section; belongs to the aspartokinase family. (911 aa)
GAPCP1Glyceraldehyde-3-phosphate dehydrogenase GAPCP1, chloroplastic; Involved in plastidial glycolytic pathway and plays a specific role in glycolytic energy production in non-green plastids and chloroplasts. Essential for breakdown of starch to form sucrose for export to non-photosynthetic tissues, and to generate primary metabolites for anabolic pathways such as fatty acid and amino acid synthesis. Plays an important role in plant development by providing substrates for the phosphorylated pathway of serine biosynthesis in roots. Plays a crucial role in pollen development. Functionally red [...] (422 aa)
PDK[Pyruvate dehydrogenase (acetyl-transferring)] kinase, mitochondrial; Serine protein kinase that inhibits the mitochondrial pyruvate dehydrogenase (PDH) complex (mtPDC) by phosphorylation of the E1 alpha subunit on Ser residues, thus contributing to the regulation of glucose metabolism. (366 aa)
T28P16.12Probable fructokinase-1; May play an important role in maintaining the flux of carbon towards starch formation. (325 aa)
PATBifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase; Prokaryotic-type aspartate aminotransferase. Has also a prenate transaminase activity. Involved in the aromatic amino acids biosynthesis pathway via the arogenate route. Required for the transamination of prephenate into arogenate. Required for early development of the embryo. (475 aa)
F1O11.21Pyruvate kinase; Belongs to the pyruvate kinase family. (527 aa)
PGR5Protein PROTON GRADIENT REGULATION 5, chloroplastic; Involved in the regulation of the cyclic electron flow (CEF) around Photosystem I. Essential for the reduction of PGRL1A by ferredoxin and for photoprotection. (133 aa)
T11I18.16Pyruvate kinase; Belongs to the pyruvate kinase family. (510 aa)
FAS1Chromatin assembly factor 1 subunit FAS1; Component of the chromatin assembly factor complex (CAF-1) involved in chromatin assembly following DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. Required for several aspects of development, including seedling growth and leaf hair differentiation. Plays a critical role in the organization of shoot apical meristem (SAM) and root apical meristem (RAM) during postembryonic development by facilitating stable maintenance of gene expression states. Seems not required to maintain transcriptional repression o [...] (815 aa)
PSBSPhotosystem II 22 kDa protein, chloroplastic; Plays an important role in non-photochemical quenching, a process maintains the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage. Is not necessary for efficient light harvesting and photosynthesis. Belongs to the ELIP/psbS family. (265 aa)
ABCB1ABC transporter B family member 1; Auxin efflux transporter that acts as a negative regulator of light signaling to promote hypocotyl elongation. Mediates the accumulation of chlorophyll and anthocyanin, as well as the expression of genes in response to light. Participates directly in auxin efflux and thus regulates the polar (presumably basipetal) auxin transport (from root tips to root elongating zone). Transports also some auxin metabolites such as oxindoleacetic acid and indoleacetaldehyde. Involved in diverse auxin-mediated responses including gravitropism, phototropism and latera [...] (1286 aa)
ABCG2ABC transporter G family member 2. (755 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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