STRINGSTRING
NMAT4 NMAT4 ABO6 ABO6 TMN4 TMN4 RUG3 RUG3 RAD52-1 RAD52-1 RH53 RH53 MSL1.5 MSL1.5 OTP43 OTP43 NDB4 NDB4 BIR6 BIR6 ABO5 ABO5 WTF9 WTF9 SF1 SF1 nad1 nad1 nad5 nad5 nad2 nad2 nad4 nad4 matR matR ND2 ND2 ND5 ND5 BIO2 BIO2 ND1 ND1 ND4 ND4 Q0WVW4_ARATH Q0WVW4_ARATH AOX1A AOX1A T27F4.19 T27F4.19 NDA1 NDA1 F3D13.1 F3D13.1 MTERF15 MTERF15 NMAT1 NMAT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NMAT4Nuclear intron maturase 4, mitochondrial; Nuclear-encoded maturase required for splicing of group-II introns in mitochondria. Involved in NAD1 pre-mRNA processing and maturation of introns 1, 3 and 4. Necessary for mitochondrial biogenesis during early developmental stages. Essential for respiratory holocomplex I biogenesis in mitochondria. (798 aa)
ABO6ATP-dependent RNA helicase A-like protein. (1161 aa)
TMN4Transmembrane 9 superfamily member 4; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (593 aa)
RUG3RCC1 domain-containing protein RUG3, mitochondrial; Regulates DNA damage response (DDR) synergistically with ATM. Together with ATM, involved in the splicing of the ND2/NAD2 mRNA. Required for the accumulation of mitochondrial respiratory chain complex I. Negative regulator of plant responses to abscisic acid (ABA). May have a pivotal role in vegetative growth and the phase transition from vegetative to reproductive growth. (445 aa)
RAD52-1DNA repair RAD52-like protein 1, mitochondrial; Plant-specific single-stranded DNA-binding protein required for efficient heterologous recombination-dependent DNA repair in nuclear and mitochondrial compartments. Forms large nucleo-protein complexes with WHY2 in mitochondria. Binds ssDNA with high affinity, but with little sequence specificity. Involved in double-stranded DNA break repair. Involved in the hydrolytic splicing pathway in mitochondrion. Facilitates the excision of two cis-spliced group II introns, NAD1 intron 2 and NAD2 intron 1 ; Belongs to the RAD52 family. (176 aa)
RH53DEAD-box ATP-dependent RNA helicase 53, mitochondrial. (616 aa)
MSL1.5Pentatricopeptide repeat-containing protein At3g16010; Belongs to the PPR family. P subfamily. (642 aa)
OTP43Pentatricopeptide repeat-containing protein At1g74900, mitochondrial; Required for the trans-splicing of intron 1 of the mitochondrial nad1 transcript encoding the ND1 subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). (482 aa)
NDB4External alternative NAD(P)H-ubiquinone oxidoreductase B4, mitochondrial; Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane (By similarity). NAD(P)H dehydrogenase; more efficient on NADH. (582 aa)
BIR6Pentatricopeptide repeat-containing protein At3g48250, chloroplastic. (621 aa)
ABO5Pentatricopeptide repeat-containing protein At1g51965, mitochondrial. (650 aa)
WTF9Protein WHAT'S THIS FACTOR 9, mitochondrial; RNA-binding protein involved in group II intron splicing. Binds specific group II introns and promotes their splicing (e.g. rpl2 and ccmFC). (387 aa)
SF1Splicing factor-like protein 1; Necessary for the splicing of pre-mRNA. Required during development and for abscisic acid (ABA) responses. Belongs to the BBP/SF1 family. (804 aa)
nad1NADH-ubiquinone oxidoreductase chain 1; Belongs to the complex I subunit 1 family. (325 aa)
nad5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (669 aa)
nad2NADH dehydrogenase subunit 2. (488 aa)
nad4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (495 aa)
matRMaturase. (656 aa)
ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (499 aa)
ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (669 aa)
BIO2Biotin synthase, mitochondrial. (378 aa)
ND1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (325 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (495 aa)
Q0WVW4_ARATHRNA-binding KH domain-containing protein. (607 aa)
AOX1AUbiquinol oxidase 1a, mitochondrial; Catalyzes the cyanide-resistant oxidation of ubiquinol and the reduction of molecular oxygen to water, but does not translocate protons and consequently is not linked to oxidative phosphorylation. Increases respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures. (354 aa)
T27F4.19Pentatricopeptide repeat-containing protein At1g66345, mitochondrial. (544 aa)
NDA1Internal alternative NAD(P)H-ubiquinone oxidoreductase A1, mitochondrial; Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane. (510 aa)
F3D13.1Pentatricopeptide repeat-containing protein At4g01400, mitochondrial. (466 aa)
MTERF15Transcription termination factor MTERF15, mitochondrial; Transcription termination factor required for mitochondrial NAD2 intron 3 splicing and normal membrane respiratory chain Complex I activity. Essential for normal plant growth and development. Binds to RNA but not to double-stranded DNA. (445 aa)
NMAT1Nuclear intron maturase 1, mitochondrial; Nuclear-encoded maturase required for splicing of group-II introns in mitochondria. Necessary for mitochondrial biogenesis during early developmental stages. Involved in the splicing of mitochondrial NAD4 transcripts. Required for trans-splicing of NAD1 intron 1 and also functions in cis-splicing of NAD2 intron 1 and NAD4 intron 2. Required for the regulation of fundamental metabolic pathways such as amino acid metabolism, triacylglycerol degradation and polysaccharide synthesis (cellulose and starch) during the early stage of plant growth. Imp [...] (711 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (16%) [HD]