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MYB90 MYB90 FLS5 FLS5 FLS3 FLS3 ZEP ZEP TT2 TT2 MYB114 MYB114 MYB113 MYB113 NCED6 NCED6 NCED3 NCED3 A3G2XYLT A3G2XYLT DTX41 DTX41 MYB11 MYB11 CLH2 CLH2 NCED9 NCED9 F3H F3H AP4M AP4M BAN BAN UBC23 UBC23 F1C9.19 F1C9.19 FLS6 FLS6 FLS4 FLS4 MYB12 MYB12 CLH1 CLH1 NCED2 NCED2 CCD4 CCD4 CHS CHS DFRA DFRA LDOX LDOX FLS1 FLS1 NCED5 NCED5 BZIP8 BZIP8 MYB75 MYB75
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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MYB90Transcription factor MYB90; Transcription activator, when associated with BHLH12/MYC1, EGL3, or GL3. Promotes the synthesis of phenylpropanoid-derived compounds such as anthocyanins. (249 aa)
FLS5Probable flavonol synthase 5; Belongs to the iron/ascorbate-dependent oxidoreductase family. (325 aa)
FLS3Flavonol synthase 3; Catalyzes the formation of flavonols from dihydroflavonols. Possesses low activity in vitro towards dihydrokaempferol and dihydroquercetin producing kaempferol and quercitin, respectively. Belongs to the iron/ascorbate-dependent oxidoreductase family. (308 aa)
ZEPZeaxanthin epoxidase, chloroplastic; Zeaxanthin epoxidase that plays an important role in the xanthophyll cycle and abscisic acid (ABA) biosynthesis. Converts zeaxanthin into antheraxanthin and subsequently violaxanthin. Required for resistance to osmotic and drought stresses, ABA-dependent stomatal closure, seed development and dormancy, modulation of defense gene expression and disease resistance and non-photochemical quencing (NPQ). Through its role in ABA biosynthesis, regulates the expression of stress-responsive genes such as RD29A during osmotic stress and is required for normal [...] (667 aa)
TT2Transcription factor TT2; Transcription activator, when associated with BHLH2/EGL3/MYC146, BHLH12/MYC1, or BHLH42/TT8. Involved in the control of flavonoid late metabolism in developing siliques. Plays a key role in determining the tissue-specific activation of leucoanthocyanidin reductase (BANYULS). (258 aa)
MYB114Transcription factor MYB114; Transcription activator, when associated with BHLH002/EGL3/MYC146, BHLH012/MYC1, or BHLH042/TT8. (139 aa)
MYB113Transcription factor MYB113; Transcription activator, when associated with BHLH002/EGL3/MYC146, BHLH012/MYC1, or BHLH042/TT8. (246 aa)
NCED69-cis-epoxycarotenoid dioxygenase NCED6, chloroplastic; Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity. Catalyzes the first step of abscisic-acid biosynthesis from carotenoids. Contributes probably to abscisic acid synthesis for the induction of seed dormancy. (577 aa)
NCED39-cis-epoxycarotenoid dioxygenase NCED3, chloroplastic; Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity. Catalyzes the first step of abscisic-acid biosynthesis from carotenoids, in response to water stress. (599 aa)
A3G2XYLTAnthocyanidin 3-O-glucoside 2'''-O-xylosyltransferase; Contributes to the last few anthocyanin biosynthetic steps. Converts cyanidin 3-O-glucoside to cyanidin 3-O-xylosyl(1->2)glucoside. Can use 3-O-glucosylated anthocyanidins/flavonols and uridine diphosphate (UDP)-xylose as substrates. (468 aa)
DTX41Protein DETOXIFICATION 41; Acts as a flavonoid/H(+)-antiporter that control the vacuolar sequestration of flavonoids in the seed coat endothelium. Could transport the anthocyanin cyanidin-3-O-glucoside and epicatechin 3'-O-glucoside in vitro. (507 aa)
MYB11Transcription factor MYB11; Modulates overall growth by reducing the proliferation activity of meristematic cells and delaying development. Flavonol-specific transcription activator involved in the regulation of several genes of flavonoid biosynthesis. Activates the expression of CHS, CHI, F3H and FLS1. Confers tolerance to UV-B. (343 aa)
CLH2Chlorophyllase-2, chloroplastic; Catalyzes the hydrolysis of ester bond in chlorophyll to yield chlorophyllide and phytol. (318 aa)
NCED99-cis-epoxycarotenoid dioxygenase NCED9, chloroplastic; Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity. Catalyzes the first step of abscisic-acid biosynthesis from carotenoids. Contributes probably to abscisic acid synthesis for the induction of seed dormancy. (657 aa)
F3HNaringenin,2-oxoglutarate 3-dioxygenase; Catalyzes the 3-beta-hydroxylation of 2S-flavanones to 2R,3R- dihydroflavonols which are intermediates in the biosynthesis of flavonols, anthocyanidins, catechins and proanthocyanidins in plants. (358 aa)
AP4MAP-4 complex subunit mu; Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes medium subunit family. (451 aa)
BANAnthocyanidin reductase; Involved in the biosynthesis of condensed tannins. Converts cyanidin into (-)-epicatechin as the major product. Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. (340 aa)
UBC23Probable ubiquitin-conjugating enzyme E2 23; Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. (1102 aa)
F1C9.19Transferase. (666 aa)
FLS6Probable flavonol synthase 6. (293 aa)
FLS4Probable flavonol synthase 4. (279 aa)
MYB12Transcription factor MYB12; Flavonol-specific transcription activator involved in the regulation of several genes of flavonoid biosynthesis. Activates the expression of CHS, CHI, F3H and FLS1. Controls flavonol biosynthesis mainly in the root. Confers tolerance to UV-B. (371 aa)
CLH1Chlorophyllase-1; Catalyzes the hydrolysis of ester bond in chlorophyll to yield chlorophyllide and phytol. Shows a preferential activity toward chlorophyll a; Belongs to the AB hydrolase superfamily. Lipase family. (324 aa)
NCED29-cis-epoxycarotenoid dioxygenase NCED2, chloroplastic; Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity. Catalyzes the first step of abscisic-acid biosynthesis from carotenoids; Belongs to the carotenoid oxygenase family. (583 aa)
CCD4Probable carotenoid cleavage dioxygenase 4, chloroplastic; May be involved in carotenoid cleavage; Belongs to the carotenoid oxygenase family. (595 aa)
CHSChalcone synthase; The primary product of this enzyme is 4,2',4',6'- tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin. (395 aa)
DFRADihydroflavonol 4-reductase; Bifunctional enzyme involved in flavonoid metabolism. (382 aa)
LDOXLeucoanthocyanidin dioxygenase; Involved in anthocyanin and protoanthocyanidin biosynthesis by catalyzing the oxidation of leucoanthocyanidins into anthocyanidins. Possesses low flavonol synthase activity in vitro towards dihydrokaempferol and dihydroquercetin producing kaempferol and quercitin, respectively. Belongs to the iron/ascorbate-dependent oxidoreductase family. (356 aa)
FLS1Flavonol synthase/flavanone 3-hydroxylase; Catalyzes the formation of flavonols from dihydroflavonols. It can act on dihydrokaempferol to produce kaempferol, on dihydroquercetin to produce quercitin and on dihydromyricetin to produce myricetin. In vitro catalyzes the oxidation of both enantiomers of naringenin to give both cis- and trans-dihydrokaempferol. Belongs to the iron/ascorbate-dependent oxidoreductase family. (336 aa)
NCED5Probable 9-cis-epoxycarotenoid dioxygenase NCED5, chloroplastic; Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity. Catalyzes the first step of abscisic-acid biosynthesis from carotenoids (By similarity); Belongs to the carotenoid oxygenase family. (589 aa)
BZIP8Basic leucine zipper 8; Belongs to the bZIP family. (138 aa)
MYB75Transcription factor MYB75; Transcription activator, when associated with BHLH12/MYC1, EGL3, or GL3. Promotes the synthesis of. phenylpropanoid-derived compounds such as anthocyanins and proanthocyanidin, probably together with GL3 and BHLH2. Regulates the expression of CHS, DFRA, LDOX, and BAN. (248 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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