STRINGSTRING
NAD9 NAD9 nad1 nad1 nad5 nad5 nad2 nad2 nad9 nad9 ccmFC ccmFC nad4 nad4 mttB mttB rpl2 rpl2 nad7 nad7 matR matR ND2 ND2 CYTC-1 CYTC-1 ND5 ND5 RPL8A RPL8A rpl2-A rpl2-A ATPA ATPA ND1 ND1 CCMFC CCMFC NAD7 NAD7 RPL2 RPL2 ND4 ND4 TMN1 TMN1 MTERF15 MTERF15 NMAT1 NMAT1 TMN4 TMN4 RUG3 RUG3 UPF1 UPF1 NMAT2 NMAT2 PNM1 PNM1 MSJ1.11 MSJ1.11 RAD52-1 RAD52-1 RH53 RH53 T22E16.240 T22E16.240 PCMP-E76 PCMP-E76 ABO5 ABO5 WTF9 WTF9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NAD9NADH dehydrogenase [ubiquinone] iron-sulfur protein 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (190 aa)
nad1NADH-ubiquinone oxidoreductase chain 1; Belongs to the complex I subunit 1 family. (325 aa)
nad5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (669 aa)
nad2NADH dehydrogenase subunit 2. (488 aa)
nad9NADH dehydrogenase subunit 9; Belongs to the complex I 30 kDa subunit family. (190 aa)
ccmFCCytochrome c biogenesis FC. (442 aa)
nad4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (495 aa)
mttBTransport membrane protein. (280 aa)
rpl2Ribosomal protein L2. (349 aa)
nad7NADH dehydrogenase subunit 7; Belongs to the complex I 49 kDa subunit family. (394 aa)
matRMaturase. (656 aa)
ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (499 aa)
CYTC-1Cytochrome c-1; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (114 aa)
ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (669 aa)
RPL8A60S ribosomal protein L8-1. (258 aa)
rpl2-A50S ribosomal protein L2, chloroplastic; Belongs to the universal ribosomal protein uL2 family. (274 aa)
ATPAATP synthase subunit alpha, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the [...] (507 aa)
ND1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (325 aa)
CCMFCCytochrome c biogenesis CcmF C-terminal-like mitochondrial protein; Forms a complex with CCMFN1, CCMFN2 and CCMH that performs the assembly of heme with c-type apocytochromes in mitochondria. Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family. (442 aa)
NAD7NADH dehydrogenase [ubiquinone] iron-sulfur protein 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). Component of the iron-sulfur (IP) fragment of the enzyme. (394 aa)
RPL260S ribosomal protein L2, mitochondrial; Belongs to the universal ribosomal protein uL2 family. (349 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (495 aa)
TMN1Transmembrane 9 superfamily member 1. (589 aa)
MTERF15Transcription termination factor MTERF15, mitochondrial; Transcription termination factor required for mitochondrial NAD2 intron 3 splicing and normal membrane respiratory chain Complex I activity. Essential for normal plant growth and development. Binds to RNA but not to double-stranded DNA. (445 aa)
NMAT1Nuclear intron maturase 1, mitochondrial; Nuclear-encoded maturase required for splicing of group-II introns in mitochondria. Necessary for mitochondrial biogenesis during early developmental stages. Involved in the splicing of mitochondrial NAD4 transcripts. Required for trans-splicing of NAD1 intron 1 and also functions in cis-splicing of NAD2 intron 1 and NAD4 intron 2. Required for the regulation of fundamental metabolic pathways such as amino acid metabolism, triacylglycerol degradation and polysaccharide synthesis (cellulose and starch) during the early stage of plant growth. Imp [...] (711 aa)
TMN4Transmembrane 9 superfamily member 4; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (593 aa)
RUG3RCC1 domain-containing protein RUG3, mitochondrial; Regulates DNA damage response (DDR) synergistically with ATM. Together with ATM, involved in the splicing of the ND2/NAD2 mRNA. Required for the accumulation of mitochondrial respiratory chain complex I. Negative regulator of plant responses to abscisic acid (ABA). May have a pivotal role in vegetative growth and the phase transition from vegetative to reproductive growth. (445 aa)
UPF1Regulator of nonsense transcripts 1 homolog; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (premature termination codon PTC) by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Eliminates the production of nonsense-containing RNAs (ncRNAs). Required for plant development and adaptation to environmental stresses, including plant defense and response to wounding. Belongs to the DNA2/NAM7 helicase family. (1254 aa)
NMAT2Nuclear intron maturase 2, mitochondrial; Nuclear-encoded maturase required for splicing of group-II introns in mitochondria. Involved in the splicing of mitochondrial COX2, NAD1 and NAD7 transcripts. Necessary for mitochondrial biogenesis during early developmental stages. (735 aa)
PNM1Pentatricopeptide repeat-containing protein PNM1, mitochondrial; RNA-binding protein that functions in both mitochondrion and nucleus. In mitochondrion, it is associated with polysomes and may play a role in translation. Required during embryogenesis. In nucleus, might be involved in the regulation of its own gene expression. Belongs to the PPR family. P subfamily. (521 aa)
MSJ1.11Nuclear protein-like. (1269 aa)
RAD52-1DNA repair RAD52-like protein 1, mitochondrial; Plant-specific single-stranded DNA-binding protein required for efficient heterologous recombination-dependent DNA repair in nuclear and mitochondrial compartments. Forms large nucleo-protein complexes with WHY2 in mitochondria. Binds ssDNA with high affinity, but with little sequence specificity. Involved in double-stranded DNA break repair. Involved in the hydrolytic splicing pathway in mitochondrion. Facilitates the excision of two cis-spliced group II introns, NAD1 intron 2 and NAD2 intron 1 ; Belongs to the RAD52 family. (176 aa)
RH53DEAD-box ATP-dependent RNA helicase 53, mitochondrial. (616 aa)
T22E16.240Regulator of chromosome condensation (RCC1) family protein. (488 aa)
PCMP-E76Pentatricopeptide repeat-containing protein At2g13600; Belongs to the PPR family. PCMP-E subfamily. (697 aa)
ABO5Pentatricopeptide repeat-containing protein At1g51965, mitochondrial. (650 aa)
WTF9Protein WHAT'S THIS FACTOR 9, mitochondrial; RNA-binding protein involved in group II intron splicing. Binds specific group II introns and promotes their splicing (e.g. rpl2 and ccmFC). (387 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.