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GLX2-4 GLX2-4 DJ1E DJ1E CSY3 CSY3 GLX2-5 GLX2-5 DJ1B DJ1B DJ1D DJ1D DJ1F DJ1F CSY5 CSY5 CSY1 CSY1 CSY2 CSY2 CCS CCS DJ1A DJ1A GLY3 GLY3 CAT2-2 CAT2-2 F1N21.10 F1N21.10 DJ1C DJ1C GLX2-1 GLX2-1 GLX2-2 GLX2-2 GLX1 GLX1 A1 A1 CSY4 CSY4 T6D22.20 T6D22.20
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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GLX2-4Probable hydroxyacylglutathione hydrolase 2, chloroplastic; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid; Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. (331 aa)
DJ1EDJ-1 protein homolog E; May be involved in oxidative stress response; Belongs to the peptidase C56 family. (398 aa)
CSY3Citrate synthase 3, peroxisomal; Peroxisomal citrate synthase required for the fatty acid respiration in seedlings, citrate being exported from peroxisomes into mitochondria during respiration of triacylglycerol (TAG). Indeed, complete respiration requires the transfer of carbon in the form of citrate from the peroxisome to the mitochondria. (509 aa)
GLX2-5Hydroxyacylglutathione hydrolase 2, mitochondrial; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (324 aa)
DJ1BProtein DJ-1 homolog B; May be involved in oxidative stress response. (438 aa)
DJ1DProtein DJ-1 homolog D; Possesses glyoxalase I activity. Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S- lactoylglutathione. May be involved in oxidative stress response. (388 aa)
DJ1FDJ-1 protein homolog F; May be involved in oxidative stress response; Belongs to the peptidase C56 family. (399 aa)
CSY5Citrate synthase 5, mitochondrial; Belongs to the citrate synthase family. (464 aa)
CSY1Citrate synthase 1, peroxisomal; Belongs to the citrate synthase family. (480 aa)
CSY2Citrate synthase 2, peroxisomal; Peroxisomal citrate synthase required for the fatty acid respiration in seedlings, citrate being exported from peroxisomes into mitochondria during respiration of triacylglycerol (TAG). Indeed, complete respiration requires the transfer of carbon in the form of citrate from the peroxisome to the mitochondria. (514 aa)
CCSCopper chaperone for superoxide dismutase, chloroplastic/cytosolic; Copper chaperone for the superoxide dismutases CSD1, CSD2 and CSD3. Binds copper ions and delivers them specifically to CSDs. Is required for assistance in CSDs disulfide bond formation and thereby activation of CSDs. May be involved in the negative regulation of heat stress-responsive genes and thermotolerance. (320 aa)
DJ1AProtein DJ-1 homolog A; Involved in oxidative stress response. Confers protection against diverse stresses by binding both CSD1 and GPX2 and mediating the cytosolic activation of the Cu-Zn-dependent superoxide dismutase activity of CSD1; Belongs to the peptidase C56 family. (392 aa)
GLY3Persulfide dioxygenase ETHE1 homolog, mitochondrial; Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) gives rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R- SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic effects, due to the [...] (294 aa)
CAT2-2Cationic amino acid transporter 2, vacuolar; Permease involved in the transport of the cationic amino acids. (635 aa)
F1N21.10Probable lactoylglutathione lyase, chloroplastic; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (350 aa)
DJ1CProtein DJ-1 homolog C; Plays an essential role in chloroplast development and is required for chloroplast integrity and viability. Belongs to the peptidase C56 family. (472 aa)
GLX2-1Hydroxyacylglutathione hydrolase 1, mitochondrial; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (331 aa)
GLX2-2Hydroxyacylglutathione hydrolase cytoplasmic; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. (258 aa)
GLX1Lactoylglutathione lyase GLX1; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (283 aa)
A1Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (449 aa)
CSY4Citrate synthase 4, mitochondrial; Belongs to the citrate synthase family. (474 aa)
T6D22.20Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (185 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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