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FLS1 FLS1 DTX35 DTX35 FLS6 FLS6 FLS4 FLS4 HY5 HY5 PSBP2 PSBP2 CIP7 CIP7 CHS CHS GSA1 GSA1 HEMA1 HEMA1 COP1 COP1 DFRA DFRA CYP73A5 CYP73A5 AHA10 AHA10 TIR1 TIR1 SPL9 SPL9 CHI3 CHI3 HYH HYH LDOX LDOX MYBL2 MYBL2 GSTF12 GSTF12 FLS5 FLS5 FLS3 FLS3 TT2 TT2 LBD37 LBD37 5MAT 5MAT LHCB6 LHCB6 DTX41 DTX41 F3H F3H CYP75B1 CYP75B1 BAN BAN LBD38 LBD38 PSAH2 PSAH2 LBD39 LBD39
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second shell of interactors
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proteins of unknown 3D structure
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FLS1Flavonol synthase/flavanone 3-hydroxylase; Catalyzes the formation of flavonols from dihydroflavonols. It can act on dihydrokaempferol to produce kaempferol, on dihydroquercetin to produce quercitin and on dihydromyricetin to produce myricetin. In vitro catalyzes the oxidation of both enantiomers of naringenin to give both cis- and trans-dihydrokaempferol. Belongs to the iron/ascorbate-dependent oxidoreductase family. (336 aa)
DTX35Protein DETOXIFICATION 35; Multidrug and toxin efflux transporter involved in flavonoid metabolism. Required for proper reproductive development. (488 aa)
FLS6Probable flavonol synthase 6. (293 aa)
FLS4Probable flavonol synthase 4. (279 aa)
HY5Transcription factor HY5; Transcription factor that promotes photomorphogenesis in light. Acts downstream of the light receptor network and directly affects transcription of light-induced genes. Specifically involved in the blue light specific pathway, suggesting that it participates in transmission of cryptochromes (CRY1 and CRY2) signals to downstream responses. In darkness, its degradation prevents the activation of light-induced genes (Probable). Acts coordinately with SPL7 to regulate the microRNA miR408 and its target genes in response to changes in light and copper conditions. R [...] (168 aa)
PSBP2Putative oxygen-evolving enhancer protein 2-2; Belongs to the psbP family. (125 aa)
CIP7COP1-interacting protein 7; Exhibits transcriptional activation activity. Positive regulator of light-regulated genes, probably being a direct downstream target of COP1 for mediating light control of gene expression. (1058 aa)
CHSChalcone synthase; The primary product of this enzyme is 4,2',4',6'- tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin. (395 aa)
GSA1Glutamate-1-semialdehyde 2,1-aminomutase 1, chloroplastic; Transaminase converting glutamate 1-semialdehyde (GSA) to 5- aminolevulinate (ALA). Involved in the biosynthesis of tetrapyrroles. (474 aa)
HEMA1Glutamyl-tRNA reductase 1, chloroplastic; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). Probably involved in the tetrapyrrole synthesis required for the chlorophyll biosynthesis. (543 aa)
COP1E3 ubiquitin-protein ligase COP1; E3 ubiquitin-protein ligase that acts as a repressor of photomorphogenesis and as an activator of etiolation in darkness. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Represses photomorphogenesis in darkness by mediating ubiquitination and subsequent proteasomal degradation of light-induced transcription factors such as HY5, HYH and LAF1. Down-regulates MYB21, probably via ubiquitination process. Light stimuli abrogate the repre [...] (675 aa)
DFRADihydroflavonol 4-reductase; Bifunctional enzyme involved in flavonoid metabolism. (382 aa)
CYP73A5Trans-cinnamate 4-monooxygenase; Controls carbon flux to pigments essential for pollination or UV protection, to numerous pytoalexins synthesized by plants when challenged by pathogens, and to lignins. (505 aa)
AHA10ATPase 10, plasma membrane-type; The plasma membrane H(+) ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. (947 aa)
TIR1Protein TRANSPORT INHIBITOR RESPONSE 1; Auxin receptor that mediates Aux/IAA proteins proteasomal degradation and auxin-regulated transcription. The SCF(TIR1) E3 ubiquitin ligase complex is involved in auxin-mediated signaling pathway that regulate root and hypocotyl growth, lateral root formation, cell elongation, and gravitropism. Appears to allow pericycle cells to overcome G2 arrest prior to lateral root development. Plays a role in ethylene signaling in roots. Confers sensitivity to the virulent bacterial pathogen P.syringae. (594 aa)
SPL9Squamosa promoter-binding-like protein 9; Trans-acting factor that binds specifically to the consensus nucleotide sequence 5'-TNCGTACAA-3'. (375 aa)
CHI3Probable chalcone--flavonone isomerase 3; Involved in anthocyanin biosynthesis. Belongs to the chalcone isomerase family. (209 aa)
HYHTranscription factor HY5-like; Transcription factor that promotes photomorphogenesis in light. Acts downstream of the light receptor network and directly affects transcription of light-induced genes. Specifically involved in the blue light specific pathway, suggesting that it participates in transmission of cryptochromes (CRY1 and CRY2) signals to downstream responses. In darkness, its degradation prevents the activation of light-induced genes; Belongs to the bZIP family. (149 aa)
LDOXLeucoanthocyanidin dioxygenase; Involved in anthocyanin and protoanthocyanidin biosynthesis by catalyzing the oxidation of leucoanthocyanidins into anthocyanidins. Possesses low flavonol synthase activity in vitro towards dihydrokaempferol and dihydroquercetin producing kaempferol and quercitin, respectively. Belongs to the iron/ascorbate-dependent oxidoreductase family. (356 aa)
MYBL2Putative transcription factor; 20982-20139. (195 aa)
GSTF12Glutathione S-transferase F12; Involved in the transport and/or accumulation of both anthocyanins and proanthocyanidins (PA)s in the vacuole. Functions in the cytosol to maintain the regular accumulation in the vacuole of PA precursors, such as epicatechin and glycosylated epicatechin. (214 aa)
FLS5Probable flavonol synthase 5; Belongs to the iron/ascorbate-dependent oxidoreductase family. (325 aa)
FLS3Flavonol synthase 3; Catalyzes the formation of flavonols from dihydroflavonols. Possesses low activity in vitro towards dihydrokaempferol and dihydroquercetin producing kaempferol and quercitin, respectively. Belongs to the iron/ascorbate-dependent oxidoreductase family. (308 aa)
TT2Transcription factor TT2; Transcription activator, when associated with BHLH2/EGL3/MYC146, BHLH12/MYC1, or BHLH42/TT8. Involved in the control of flavonoid late metabolism in developing siliques. Plays a key role in determining the tissue-specific activation of leucoanthocyanidin reductase (BANYULS). (258 aa)
LBD37LOB domain-containing protein 37. (250 aa)
5MATMalonyl-CoA:anthocyanidin 5-O-glucoside-6''-O-malonyltransferase; Involved in the malonylation of the 5-O-glucose residue of anthocyanin. Acts only on anthocyanin substrates containing a 5-O glucosyl moiety. Not able to catalyze acyl transfer using acetyl-CoA, butyryl-CoA, hexanoyl- CoA, benzoyl-CoA, cinnamoyl-CoA, methylmalonyl- CoA, succinyl-CoA, p-coumaroyl-CoA or caffeoyl-CoA. (449 aa)
LHCB6Chlorophyll a-b binding protein, chloroplastic; The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated; Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family. (258 aa)
DTX41Protein DETOXIFICATION 41; Acts as a flavonoid/H(+)-antiporter that control the vacuolar sequestration of flavonoids in the seed coat endothelium. Could transport the anthocyanin cyanidin-3-O-glucoside and epicatechin 3'-O-glucoside in vitro. (507 aa)
F3HNaringenin,2-oxoglutarate 3-dioxygenase; Catalyzes the 3-beta-hydroxylation of 2S-flavanones to 2R,3R- dihydroflavonols which are intermediates in the biosynthesis of flavonols, anthocyanidins, catechins and proanthocyanidins in plants. (358 aa)
CYP75B1Flavonoid 3'-monooxygenase; Catalyzes the 3'-hydroxylation of the flavonoid B-ring to the 3',4'-hydroxylated state. Convert naringenin to eriodictyol and dihydrokaempferol to dihydroquercetin; Belongs to the cytochrome P450 family. (513 aa)
BANAnthocyanidin reductase; Involved in the biosynthesis of condensed tannins. Converts cyanidin into (-)-epicatechin as the major product. Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily. (340 aa)
LBD38LOB domain-containing protein 38; Belongs to the LOB domain-containing protein family. (247 aa)
PSAH2Photosystem I reaction center subunit VI-2, chloroplastic; Possible role could be the docking of the LHC I antenna complex to the core complex; Belongs to the psaH family. (145 aa)
LBD39LOB domain-containing protein 39. (240 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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