STRINGSTRING
F11I4.15 F11I4.15 T22N19.10 T22N19.10 T22N19.30 T22N19.30 GH3.3 GH3.3 T26J12.7 T26J12.7 ACX2 ACX2 ACX1 ACX1 GH3.5 GH3.5 GH3.1 GH3.1 ACT1 ACT1 ACX3 ACX3 F3E22.17 F3E22.17 AP2 AP2 KAS1 KAS1 accD accD RABB1C RABB1C WDL3 WDL3 GH3.15 GH3.15 KCR1 KCR1 ACX4 ACX4 F11I4.14 F11I4.14 F11I4.13 F11I4.13 BZIP8 BZIP8 K17N15.2 K17N15.2 GH3.17 GH3.17 ACX3.2 ACX3.2 GH3.4 GH3.4 GH3.6 GH3.6 T31B5_170 T31B5_170 GH3.12 GH3.12 SKIP35 SKIP35 F22C12.10 F22C12.10 JAR1 JAR1 THFS THFS WRKY11 WRKY11 GH3.2 GH3.2 GH3.10 GH3.10 ACX1.2 ACX1.2 T10J7.26 T10J7.26 T10J7.18 T10J7.18
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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F11I4.15Auxin-responsive GH3 family protein. (576 aa)
T22N19.10Auxin-responsive GH3 family protein. (672 aa)
T22N19.30Auxin-responsive GH3 family protein. (624 aa)
GH3.3Indole-3-acetic acid-amido synthetase GH3.3; Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin. Strongly reactive with Glu, Gln, Trp, Asp, Ala, Leu, Phe, Gly, Tyr, Met, Ile and Val. Little or no product formation with His, Ser, Thr, Arg, Lys, or Cys. Also active on pyruvic and butyric acid analogs of IAA, PAA and the synthetic auxin naphthaleneacetic acid (NAA). The two chlorinated synthetic auxin herbicides 2,4-D and 3,6-dichloro-o-anisic acid (dicamba) cannot be used as substrates [...] (595 aa)
T26J12.7Auxin-responsive GH3 family protein. (578 aa)
ACX2Acyl-coenzyme A oxidase 2, peroxisomal; Catalyzes the desaturation of long-chain acyl-CoAs to 2- trans-enoyl-CoAs. Active on substrates longer than C14 and mostly with C18-CoA. Activity on long-chain mono-unsaturated substrates is double than with the corresponding saturated substrates. (692 aa)
ACX1Peroxisomal acyl-coenzyme A oxidase 1; Catalyzes the desaturation of both long- and medium-chain acyl-CoAs to 2-trans-enoyl-CoAs. Most active with C14-CoA. Activity on long-chain mono-unsaturated substrates is 40% higher than with the corresponding saturated substrates. Seems to be an important factor in the general metabolism of root tips. May be involved in the biosynthesis of jasmonic acid. (664 aa)
GH3.5Indole-3-acetic acid-amido synthetase GH3.5; Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin. Strongly reactive with Glu, Gln, Trp, Asp, Ala, Leu, Phe, Gly, Tyr, Met, Ile and Val. Little or no product formation with His, Ser, Thr, Arg, Lys, or Cys. Also active on pyruvic and butyric acid analogs of IAA, PAA and the synthetic auxin naphthaleneacetic acid (NAA). The two chlorinated synthetic auxin herbicides 2,4-D and 3,6-dichloro-o-anisic acid (dicamba) cannot be used as substrates [...] (612 aa)
GH3.1Probable indole-3-acetic acid-amido synthetase GH3.1; Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin; Belongs to the IAA-amido conjugating enzyme family. (590 aa)
ACT1Actin-1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the reproductive actins. (377 aa)
ACX3Acyl-coenzyme A oxidase 3, peroxisomal; Catalyzes the desaturation of medium-chain acyl-CoAs to 2- trans-enoyl-CoAs. Active on C8:0- to C14:0-CoA with a maximal activity on C12:0-CoA. (675 aa)
F3E22.17Putative acyl-coenzyme A oxidase At3g06690. (187 aa)
AP2Floral homeotic protein APETALA 2; Probable transcriptional activator that promotes early floral meristem identity. Is required subsequently for the transition of an inflorescence meristem into a floral meristem. Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower, by spatially controlling the expression domains of multiple floral organ identity genes. Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in association with other repressors like LEUNIG and [...] (432 aa)
KAS13-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids (By similarity). (473 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (488 aa)
RABB1CRas-related protein RABB1c; Intracellular vesicle trafficking and protein transport. Belongs to the small GTPase superfamily. Rab family. (211 aa)
WDL3Protein WVD2-like 3; Microtubule-associated protein (MAP) that regulates the orientation of interphase cortical microtubules. Binds to, bundles and stabilizes microtubules. Required for the organization and stability of cortical microtubules in hypocotyls. Required for normal hypocotyl cell elongation. Acts as negative regulator of hypocotyl cell elongation in the light; Belongs to the TPX2 family. (338 aa)
GH3.15Indole-3-acetic acid-amido synthetase GH3.15; Indole-3-acetic acid-amido (IAA) synthetase that catalyzes the conjugation of amino acids to auxin specifically using the auxin precursor indole-3-butyric acid (IBA) and glutamine and, possibly, cysteine as substrates. Displays high catalytic activity with the auxinic phenoxyalkanoic acid herbicides 4-(2,4-dichlorophenoxy)butyric acid (2,4-DB) and to some extent 2,4-dichlorophenoxylacetic acid (2,4-D) as substrates, thus confering resistance to herbicides. Belongs to the IAA-amido conjugating enzyme family. (595 aa)
KCR1Very-long-chain 3-oxoacyl-CoA reductase 1; Beta-ketoacyl-coenzyme A reductase required for the elongation of fatty acids precursors of sphingolipids, triacylglycerols, cuticular waxes and suberin. Responsible for the first reduction step in very long-chain fatty acids (VLCFAs) synthesis. Decreased expression of KCR1 (RNAi) leads to plants with fused vegetative and reproductive organs, and abnormal trichome, epidermal cell and root morphology. Cannot be complemented by KCR2. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
ACX4Acyl-coenzyme A oxidase 4, peroxisomal; Catalyzes the desaturation of short-chain acyl-CoAs to 2- trans-enoyl-CoAs. Active on butyryl-CoA (C4), hexanoyl-CoA (C6), and octanoyl-CoA (C8). Has no activity as acyl-CoA dehydrogenase or on crotonyl-CoA (an unsaturated C4:1 carbocyclic ester) or glutaryl-CoA (a dicarboxylic ester). (436 aa)
F11I4.14Auxin-responsive GH3 family protein. (525 aa)
F11I4.13Auxin-responsive GH3 family protein. (190 aa)
BZIP8Basic leucine zipper 8; Belongs to the bZIP family. (138 aa)
K17N15.2Auxin-responsive GH3 family protein. (581 aa)
GH3.17Indole-3-acetic acid-amido synthetase GH3.17; Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin. Strongly reactive with Glu, Gln, Trp, Asp, Ala, Leu, Phe, Gly, Tyr, Met, Ile and Val. Appears to favor Glu over Asp while the other GH3 favor Asp over Glu. Little or no product formation with His, Ser, Thr, Arg, Lys, or Cys. Also active on pyruvic and butyric acid analogs of IAA, PAA and the synthetic auxin naphthaleneacetic acid (NAA). The two chlorinated synthetic auxin herbicides 2,4- [...] (609 aa)
ACX3.2Putative acyl-coenzyme A oxidase 3.2, peroxisomal; Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl- CoAs. (675 aa)
GH3.4Indole-3-acetic acid-amido synthetase GH3.4; Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin. Strongly reactive with Glu, Gln, Trp, Asp, Ala, Leu, Phe, Gly, Tyr, Met, Ile and Val. Little or no product formation with His, Ser, Thr, Arg, Lys, or Cys. Also active on pyruvic and butyric acid analogs of IAA, PAA and the synthetic auxin naphthaleneacetic acid (NAA). The two chlorinated synthetic auxin herbicides 2,4-D and 3,6-dichloro-o-anisic acid (dicamba) cannot be used as substrates [...] (597 aa)
GH3.6Indole-3-acetic acid-amido synthetase GH3.6; Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin. Strongly reactive with Glu, Gln, Trp, Asp, Ala, Leu, Phe, Gly, Tyr, Met, Ile and Val. Little or no product formation with His, Ser, Thr, Arg, Lys, or Cys. Also active on pyruvic and butyric acid analogs of IAA, PAA and the synthetic auxin naphthaleneacetic acid (NAA). The two chlorinated synthetic auxin herbicides 2,4-D and 3,6-dichloro-o-anisic acid (dicamba) cannot be used as substrates [...] (612 aa)
T31B5_170Auxin-responsive GH3 family protein. (587 aa)
GH3.124-substituted benzoates-glutamate ligase GH3.12; Catalyzes the conjugation of specific amino acids (e.g. Glu and possibly His, Lys, and Met) to their preferred acyl substrates (e.g. 4-substituted benzoates), in a magnesium ion- and ATP-dependent manner. Can use 4-substituted benzoates such as 4-aminobenzoate (pABA), 4-fluorobenzoate and 4-hydroxybenzoate (4-HBA), and, to a lesser extent, benzoate, vanillate and trans-cinnamate, but not 2-substituted benzoates and salicylic acid (SA), as conjugating acyl substrates. Involved in both basal and induced resistance in a SA-dependent manner. [...] (575 aa)
SKIP35Ankyrin repeat protein SKIP35. (611 aa)
F22C12.10WRKY transcription factor. (646 aa)
JAR1Jasmonoyl--L-amino acid synthetase JAR1; Catalyzes the synthesis of jasmonates-amino acid conjugates by adenylation; can use Ile and, in vitro at least, Val, Leu and Phe as conjugating amino acids on jasmonic acid (JA) and 9,10-dihydro-JA substrates, and to a lower extent, on 3-oxo-2-(2Z-pentenyl)- cyclopentane-1-butyric acid (OPC-4) and 12-hydroxy-JA (12-OH-JA). Can synthesize adenosine 5-tetraphosphate in vitro. Required for the JA- mediated signaling pathway that regulates many developmental and defense mechanisms, including growth root inhibition, vegetative storage proteins (VSPs) [...] (575 aa)
THFSFormate--tetrahydrofolate ligase. (634 aa)
WRKY11Probable WRKY transcription factor 11; Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element (By similarity). Regulates rhizobacterium B.cereus AR156-induced systemic resistance (ISR) to P.syringae pv. tomato DC3000, probably by activating the jasmonic acid (JA)- signaling pathway ; Belongs to the WRKY group II-d family. (325 aa)
GH3.2Indole-3-acetic acid-amido synthetase GH3.2; Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin. Strongly reactive with Glu, Gln, Trp, Asp, Ala, Leu, Phe, Gly, Tyr, Met, Ile and Val. Little or no product formation with His, Ser, Thr, Arg, Lys, or Cys. Also active on pyruvic and butyric acid analogs of IAA, PAA and the synthetic auxin naphthaleneacetic acid (NAA). The two chlorinated synthetic auxin herbicides 2,4-D and 3,6-dichloro-o-anisic acid (dicamba) cannot be used as substrates [...] (549 aa)
GH3.10Indole-3-acetic acid-amido synthetase GH3.10; Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin (By similarity). Involved in red light- specific hypocotyl elongation. May act downstream of a red light signal transduction and determine the degree of hypocotyl elongation ; Belongs to the IAA-amido conjugating enzyme family. (591 aa)
ACX1.2Putative peroxisomal acyl-coenzyme A oxidase 1.2; Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl- CoAs. (664 aa)
T10J7.26P-loop containing nucleoside triphosphate hydrolases superfamily protein. (90 aa)
T10J7.18P-loop containing nucleoside triphosphate hydrolases superfamily protein. (63 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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