STRINGSTRING
AIP1 AIP1 MYB10 MYB10 SUS4 SUS4 PFK1 PFK1 SUS3 SUS3 T16L24.30 T16L24.30 NPR2 NPR2 HKL3 HKL3 NPR5 NPR5 HAI3 HAI3 A0A1I9LS57 A0A1I9LS57 A0A1P8ARU2 A0A1P8ARU2 SPS4 SPS4 SUS5 SUS5 ABI2 ABI2 PGM3 PGM3 SRK2J SRK2J F12L6.16 F12L6.16 BHLH70 BHLH70 F24G24.60 F24G24.60 CFBP1 CFBP1 PGIC PGIC SRK2A SRK2A SRK2G SRK2G SUS1 SUS1 ABI1 ABI1 PP2CA PP2CA NPR1 NPR1 HXK2 HXK2 SUS2 SUS2 SRK2D SRK2D SRK2I SRK2I HXK1 HXK1 ATHXK4 ATHXK4 NPR4 NPR4 SAB SAB NPR3 NPR3 BPC6 BPC6 SPS3-2 SPS3-2 SRK2E SRK2E SLK2 SLK2 SPS1-2 SPS1-2 F28G11.11 F28G11.11 SRK2B SRK2B HAB1 HAB1 SRK2H SRK2H RLK RLK SAG113 SAG113 SDH SDH RRS1B RRS1B MIO24.3 MIO24.3 AHG1 AHG1 MSJ1.22 MSJ1.22 LUG LUG SUS6 SUS6 SPS2-2 SPS2-2 HXK3 HXK3 T21E18.8 T21E18.8 T21E18.7 T21E18.7 HAB2 HAB2 HKL1 HKL1 NPR6 NPR6 SRK2C SRK2C CYFBP CYFBP PGMP PGMP GAL1 GAL1 PGM2 PGM2 T28P16.12 T28P16.12 SRK2F SRK2F WRKY19 WRKY19
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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AIP1Protein phosphatase 2C 3; Involved in the negative regulation of the K(+) potassium channel AKT1 by its dephosphorylation, antagonistically to CIPK proteins (e.g. CIPK23). Functions as positive regulator of abscisic acid-mediated cell signaling during seedling growth. Involved in the regulation of seed dormancy. Acts as negative regulator of seed dormancy by inhibiting abscisic signaling and subsequently activating gibberellic acid signaling ; Belongs to the PP2C family. (442 aa)
MYB10Transcription factor MYB10; Involved in metal ions homeostasis, including iron ions (Fe) acquisition, via the regulation of NAS4 and NAS2 genes expression. Necessary for plant survival in alkaline soil where iron availability is greatly restricted. Triggers tolerance to nickel (Ni) and zinc (Zn) ions. (239 aa)
SUS4Sucrose synthase 4; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways; Belongs to the glycosyltransferase 1 family. Plant sucrose synthase subfamily. (808 aa)
PFK1ATP-dependent 6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (473 aa)
SUS3Sucrose synthase 3; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Modulates metabolic homeostasis and direct carbon towards starch synthesis in developing seeds. (809 aa)
T16L24.30Probable fructokinase-4; May play an important role in maintaining the flux of carbon towards starch formation. (326 aa)
NPR2Regulatory protein NPR2; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. (600 aa)
HKL3Probable hexokinase-like 2 protein; Fructose and glucose phosphorylating enzyme. (493 aa)
NPR5Regulatory protein NPR5; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Acts redundantly with BOP2. BOP1/2 promote leaf and floral meristem fate and determinacy in a pathway targeting AP1 and AGL24. BOP1/2 act as transcriptional co-regulators through direct interaction with TGA factors, including PAN, a direct regulator of AP1. Controls lateral organ fate through positive regulation of adaxial-abaxial polarity genes ATHB-14/PHB [...] (491 aa)
HAI3Probable protein phosphatase 2C 24. (362 aa)
A0A1I9LS57Phosphoglucan phosphatase. (114 aa)
A0A1P8ARU2Phosphotransferase. (186 aa)
SPS4Probable sucrose-phosphate synthase 4; Plays a role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP- glucose and fructose- 6-phosphate. Involved in the regulation of carbon partitioning in the leaves of plants. May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf. Plays a role for sucrose availability that is essential for plant growth and fiber elongation; Belongs to the glycosyltransferase 1 family. (1050 aa)
SUS5Sucrose synthase 5; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Functions in callose synthesis at the site of phloem sieve elements. (836 aa)
ABI2Protein phosphatase 2C 77; Repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, osmotic water permeability of the plasma membrane (Pos), high light stress, response to glucose, seed germination and inhibition of vegetative growth. During the stomatal closure regulation, modulates the inward calcium-channel permeability as well as H(2)O(2) and oxidative burst in response to ABA and dehydration. Represses GHR1 and, to some extent, SRK2E/OST1, kinases involved in the regulation of SLAC1-dependent stomatal closure. Controls [...] (423 aa)
PGM3Probable phosphoglucomutase, cytoplasmic 1; This enzyme participates in both the breakdown and synthesis of glucose; Belongs to the phosphohexose mutase family. (583 aa)
SRK2JSerine/threonine-protein kinase SRK2J; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (339 aa)
F12L6.16At2g39500/F12L6.16. (55 aa)
BHLH70Transcription factor bHLH70. (371 aa)
F24G24.60Probable fructokinase-5; May play an important role in maintaining the flux of carbon towards starch formation. (324 aa)
CFBP1Fructose-1,6-bisphosphatase 1, chloroplastic; Catalyzes the irreversible reaction from fructose-1,6- bisphosphate to fructose-6-phosphate and inorganic phosphate, to regenerate the primary CO(2) acceptor molecule, ribulose-1,5- bisphosphate (Probable). Involved in the regulation of photosynthetic electron flow and sucrose synthesis. Its activity is critical for normal plant development and important for the regulation of a wide range of metabolic processes. (417 aa)
PGICGlucose-6-phosphate isomerase, cytosolic; Belongs to the GPI family. (560 aa)
SRK2ASerine/threonine-protein kinase SRK2A. (363 aa)
SRK2GSerine/threonine-protein kinase SRK2G; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (353 aa)
SUS1Sucrose synthase 1; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways; Belongs to the glycosyltransferase 1 family. Plant sucrose synthase subfamily. (808 aa)
ABI1Protein phosphatase 2C 56; Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, osmotic water permeability of the plasma membrane (Pos), drought-induced resistance and rhizogenesis, response to glucose, high light stress, seed germination and inhibition of vegetative growth. During the stomatal closure regulation, modulates the inward calcium-channel permeability as well as the actin reorganization in guard cells in response to ABA. Involved in the resistance to the bacterial pathogen Pseudomonas syrin [...] (434 aa)
PP2CAProtein phosphatase 2C 37; Major negative regulator of abscisic acid (ABA) responses during seed germination and cold acclimation. Confers insensitivity to ABA. Modulates negatively the AKT2/3 activity, which mediates K(+) transport and membrane polarization during stress situations, probably by dephosphorylation. Prevents stomata closure by inactivating the S- type anion efflux channel SLAC1 and its activator SRK2E. Represses KIN10 activity by the specific dephosphorylation of its T-loop Thr-198, leading to a poststress inactivation of SnRK1 signaling. (399 aa)
NPR1Regulatory protein NPR1; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Key positive regulator of the SA-dependent signaling pathway that negatively regulates JA-dependent signaling pathway. Mediates the binding of TGA factors to the as-1 motif found in the pathogenesis-related PR-1 gene, leading to the transcriptional regulation of the gene defense. Controls the onset of systemic acquired resistance (SAR). Upon SAR induction, [...] (593 aa)
HXK2Hexokinase-2; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells ; Belongs to the hexokinase family. (502 aa)
SUS2Sucrose synthase 2; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Modulates metabolic homeostasis and directs carbon towards starch synthesis in developing seeds. (807 aa)
SRK2DSerine/threonine-protein kinase SRK2D; Together with SRK2I, key component and activator of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as seed germination, Pro accumulation, root growth inhibition, dormancy and seedling growth, and, to a lesser extent, stomatal closure; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (362 aa)
SRK2ISerine/threonine-protein kinase SRK2I; Together with SRK2D, key component and activator of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as seed germination, Pro accumulation, root growth inhibition, dormancy and seedling growth, and, to a lesser extent, stomatal closure. (361 aa)
HXK1Hexokinase-1; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells. Promotes roots and leaves growth. Belongs to the hexokinase family. (496 aa)
ATHXK4Hexokinase-4; Fructose and glucose phosphorylating enzyme (By similarity). May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol (By similarity). (502 aa)
NPR4Regulatory protein NPR4; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Involved in the regulation of basal defense responses against pathogens, and may be implicated in the cross-talk between the SA- and JA-dependent signaling pathways. (574 aa)
SABProtein SABRE; May be involved in membrane trafficking (By similarity). Required for cell expansion, especially in root cortex, probably by counteracting the action of ethylene in promoting cells radial expansion. Involved in female organ development. Antagonistically interacts with ethylene signaling to regulate plant responses to Pi starvation. (2603 aa)
NPR3Regulatory protein NPR3; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Involved in the regulation of basal defense responses against pathogens. (586 aa)
BPC6Protein BASIC PENTACYSTEINE6; Transcriptional regulator that specifically binds to GA-rich elements (GAGA-repeats) present in regulatory sequences of genes involved in developmental processes. (342 aa)
SPS3-2Probable sucrose-phosphate synthase 3; Plays a role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP- glucose and fructose- 6-phosphate. Involved in the regulation of carbon partitioning in the leaves of plants. May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf. Plays a role for sucrose availability that is essential for plant growth and fiber elongation. (1062 aa)
SRK2ESerine/threonine-protein kinase SRK2E; Activator of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomata closure in response to drought, darkness, high CO(2), plant pathogens, or decreases in atmospheric relative humidity (RH). Involved in the resistance to drought by avoiding water loss. Required for the stomata closure mediated by pathogen-associated molecular pattern (PAMPs) (e.g. flg22 and LPS) of pathogenic bacteria such as P.syringae pv. tomato (Pst) and E.coli O157:H7. As a plant defense process, stomata are closed transiently in order [...] (362 aa)
SLK2Probable transcriptional regulator SLK2; Probable transcription regulator that functions in the development of the carpel margin meristem similarly to SEUSS (SEU). In association with SEU, supports organ development from meristematic regions by facilitating auxin response and thus organ initiation, and by sustaining meristematic potential through the maintenance of PHABULOSA expression. DNA-binding adapter subunit of the SEU-SLK2 transcriptional corepressor of abiotic stress (e.g. salt and osmotic stress) response genes. (816 aa)
SPS1-2Sucrose-phosphate synthase 1; Plays a major role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP- glucose and fructose- 6-phosphate. Involved in the regulation of carbon partitioning in the leaves of plants. May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf. Plays a role for sucrose availability that is essential for plant growth and fiber elongation. Required for nectar secretion. (1043 aa)
F28G11.11Probable fructokinase-6, chloroplastic; May play an important role in maintaining the flux of carbon towards starch formation; Belongs to the carbohydrate kinase PfkB family. (384 aa)
SRK2BSerine/threonine-protein kinase SRK2B; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (361 aa)
HAB1Protein phosphatase 2C 16; Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, seed germination and inhibition of vegetative growth. Confers enhanced sensitivity to drought. Belongs to the PP2C family. (511 aa)
SRK2HSerine/threonine-protein kinase SRK2H; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (360 aa)
RLKLeucine-rich repeat receptor-like protein kinase. (751 aa)
SAG113Probable protein phosphatase 2C 78; Acts as negative regulator of abscisic acid (ABA) signaling for stomatal closure in leaves, and controls water loss during leaf senescence. Activated by the NAC029/NAP transcription factor during ABA signaling in senescing leaves. Functions as negative regulator of osmotic stress and ABA signaling. Acts as negative regulator of response to drought. Belongs to the PP2C family. (413 aa)
SDHSorbitol dehydrogenase; Polyol dehydrogenase that catalyzes the NAD(+)-dependent oxidation of various sugar alcohols. Is mostly active with D-sorbitol (D-glucitol), ribitol and xylitol as substrates, leading to the C2- oxidized products D-fructose, D-ribulose and D-xylulose, respectively. To a lesser extent, can also oxidize arabitol, mannitol, lactitol and maltitol in vitro. Is required for sorbitol metabolism. Cannot use NADP(+) as the electron acceptor. (364 aa)
RRS1BDisease resistance protein RRS1B; Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element (By similarity). Acts also as a disease resistance protein that specifically recognizes the AvrRps4 type III effector avirulence protein from P.syringae. Heterodimerization with RPS4B is required to form a functional complex to recognize AvrRps4 and to mediate the hypersensitive response. (1372 aa)
MIO24.3Probable fructokinase-7; May play an important role in maintaining the flux of carbon towards starch formation. (343 aa)
AHG1Probable protein phosphatase 2C 75; Negative regulator of abscisic acid (ABA) responses during seed germination; Belongs to the PP2C family. (416 aa)
MSJ1.22Inositol monophosphatase family protein; Belongs to the FBPase class 1 family. (404 aa)
LUGTranscriptional corepressor LEUNIG; Transcription repressor subunit of the SEU-LUG transcriptional corepressor of the C class floral homeotic gene AGAMOUS during the early stages of floral meristem development. Is part of the A class cadastral complex that define the boundaries between the A and C class homeotic genes expression and function. Interacts together with APETALA2 and SEUSS to repress AGAMOUS expression. Also plays a role in ovule and pollen development. Implicated in embryo and floral development. Involved in post-synthesis cell wall modifications necessary for mucilage ext [...] (931 aa)
SUS6Sucrose synthase 6; Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Functions in callose synthesis at the site of phloem sieve elements. (942 aa)
SPS2-2Probable sucrose-phosphate synthase 2; Plays a role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP- glucose and fructose- 6-phosphate. Involved in the regulation of carbon partitioning in the leaves of plants. May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf. Plays a role for sucrose availability that is essential for plant growth and fiber elongation. Required for nectar secretion. (1047 aa)
HXK3Hexokinase-like 1 protein; Fructose and glucose phosphorylating enzyme. Belongs to the hexokinase family. (493 aa)
T21E18.8Probable fructokinase-2; May play an important role in maintaining the flux of carbon towards starch formation. (329 aa)
T21E18.7Probable fructokinase-3; May play an important role in maintaining the flux of carbon towards starch formation. (345 aa)
HAB2Protein phosphatase 2C 7; Key component and repressor of the abscisic acid (ABA) signaling pathway that regulates numerous ABA responses, such as stomatal closure, seed germination and inhibition of vegetative growth. (511 aa)
HKL1Hexokinase-3; Fructose and glucose phosphorylating enzyme (By similarity). May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol (By similarity). (498 aa)
NPR6Regulatory protein NPR6; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Acts redundantly with BOP2. BOP1/2 promote leaf and floral meristem fate and determinacy in a pathway targeting AP1 and AGL24. BOP1/2 act as transcriptional co-regulators through direct interaction with TGA factors, including PAN, a direct regulator of AP1. Controls lateral organ fate through positive regulation of adaxial-abaxial polarity genes ATHB-14/PHB [...] (467 aa)
SRK2CSerine/threonine-protein kinase SRK2C; Involved in gene regulation and confers tolerance to drought and osmotic stress; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (343 aa)
CYFBPFructose-1,6-bisphosphatase, cytosolic; Catalyzes the first irreversible reaction from fructose-1,6- bisphosphate to fructose-6-phosphate and inorganic phosphate and plays an important regulatory role in sucrose biosynthesis and metabolism (Probable). Its activity is essential to regulate starch levels. Functions in fructose-mediated signaling independently of its catalytic activity in sugar metabolism. May act downstream of ABA2/GIN1, which is involved in abscisic acid (ABA) synthesis to regulate autotrophic transition and modulate early seedling establishment after seed germination. [...] (341 aa)
PGMPPhosphoglucomutase, chloroplastic; This enzyme participates in both the breakdown and synthesis of glucose; Belongs to the phosphohexose mutase family. (623 aa)
GAL1Galactokinase; Sugar-1-kinase with a very high substrate specificity for the alpha-anomeric configuration of D-galacose (D-Gal). Converts also efficiently 2-deoxy-D-Gal to 2-deoxy-D-al-1-phosphate. Belongs to the GHMP kinase family. GalK subfamily. (496 aa)
PGM2Probable phosphoglucomutase, cytoplasmic 2; This enzyme participates in both the breakdown and synthesis of glucose. (585 aa)
T28P16.12Probable fructokinase-1; May play an important role in maintaining the flux of carbon towards starch formation. (325 aa)
SRK2FSerine/threonine-protein kinase SRK2F; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (350 aa)
WRKY19Probable WRKY transcription factor 19; Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element. May act also as a disease resistance protein with a serine/threonine-protein kinase activity (By similarity). (1895 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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