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ATHB-53 ATHB-53 ATHB-12 ATHB-12 HDG8 HDG8 CLV3 CLV3 ATHB-15 ATHB-15 PXG3 PXG3 ATHB-40 ATHB-40 DREB2A DREB2A COR47 COR47 HAT2 HAT2 GL2 GL2 ATHB-5 ATHB-5 ATHB-6 ATHB-6 ATHB-7 ATHB-7 PP2CA PP2CA HAT5 HAT5 LTI65 LTI65 HAT4 HAT4 RD29A RD29A ANL2 ANL2 ATHB-8 ATHB-8 HDG4 HDG4 ATHB-13 ATHB-13 ATML1 ATML1 NAC072 NAC072 ACT2 ACT2 NAC019 NAC019 HDG5 HDG5 CDC73 CDC73 NCED3 NCED3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATHB-53Homeobox-leucine zipper protein ATHB-53; Probable transcription factor that may play a regulatory role in auxin/cytokinin signaling during root development. Belongs to the HD-ZIP homeobox family. Class I subfamily. (228 aa)
ATHB-12Homeobox-leucine zipper protein ATHB-12; Probable transcription activator that may act as growth regulators in response to water deficit. (235 aa)
HDG8Homeobox-leucine zipper protein HDG8; Probable transcription factor. (699 aa)
CLV3Protein CLAVATA 3; Extracellular signal that regulates meristem maintenance. Acts with CLV1 as a ligand-receptor pair in a signal transduction pathway coordinating growth between adjacent meristematic regions and controlling the balance between meristem cell proliferation and differentiation; Belongs to the CLV3/ESR signal peptide family. (96 aa)
ATHB-15Homeobox-leucine zipper protein ATHB-15; Probable transcription factor involved in the regulation of meristem development to promote lateral organ formation. May regulates procambial and vascular tissue formation or maintenance, and vascular development in inflorescence stems; Belongs to the HD-ZIP homeobox family. Class III subfamily. (836 aa)
PXG3Probable peroxygenase 3; Probable calcium-binding peroxygenase. May be involved in the degradation of storage lipid in oil bodies, in abiotic stress-related signaling pathway and in drought tolerance through stomatal control under water deficit conditions. (236 aa)
ATHB-40Homeobox-leucine zipper protein ATHB-40; Probable transcription factor; Belongs to the HD-ZIP homeobox family. Class I subfamily. (216 aa)
DREB2ADehydration-responsive element-binding protein 2A; Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription. Belongs to the AP2/ERF transcription factor family. ERF subfamily. (335 aa)
COR47Dehydrin COR47. (265 aa)
HAT2Homeobox-leucine zipper protein HAT2; Probable transcription factor that plays a role in auxin- mediated morphogenesis. Negatively regulates lateral root elongation. (283 aa)
GL2Homeobox-leucine zipper protein GLABRA 2; Probable transcription factor required for correct morphological development and maturation of trichomes as well as for normal development of seed coat mucilage. Regulates the frequency of trichome initiation and determines trichome spacing. (747 aa)
ATHB-5Homeobox-leucine zipper protein ATHB-5; Probable transcription factor that acts as a positive regulator of ABA-responsiveness, mediating the inhibitory effect of ABA on growth during seedling establishment. Binds to the DNA sequence 5'- CAATNATTG-3'. (312 aa)
ATHB-6Homeobox-leucine zipper protein ATHB-6; Transcription activator that may act as growth regulators in response to water deficit. Interacts with the core sequence 5'- CAATTATTA-3' of promoters in response to ABA and in an ABI1-dependent manner. Involved in the negative regulation of the ABA signaling pathway; Belongs to the HD-ZIP homeobox family. Class I subfamily. (311 aa)
ATHB-7Homeobox-leucine zipper protein ATHB-7; Probable transcription activator that may act as growth regulators in response to water deficit. (258 aa)
PP2CAProtein phosphatase 2C 37; Major negative regulator of abscisic acid (ABA) responses during seed germination and cold acclimation. Confers insensitivity to ABA. Modulates negatively the AKT2/3 activity, which mediates K(+) transport and membrane polarization during stress situations, probably by dephosphorylation. Prevents stomata closure by inactivating the S- type anion efflux channel SLAC1 and its activator SRK2E. Represses KIN10 activity by the specific dephosphorylation of its T-loop Thr-198, leading to a poststress inactivation of SnRK1 signaling. (399 aa)
HAT5Homeobox-leucine zipper protein HAT5; Probable transcription activator involved in leaf development. Binds to the DNA sequence 5'-CAAT[AT]ATTG-3'. Belongs to the HD-ZIP homeobox family. Class I subfamily. (272 aa)
LTI65Low-temperature-induced 65 kDa protein; Belongs to the LTI78/LTI65 family. (619 aa)
HAT4Homeobox-leucine zipper protein HAT4; Probable transcription factor involved in the negative regulation of cell elongation and specific cell proliferation processes such as lateral root formation and secondary growth of the vascular system. Acts as mediator of the red/far-red light effects on leaf cell expansion in the shading response. Binds to the DNA sequence 5'- CAAT[GC]ATTG-3'. Negatively regulates its own expression. Belongs to the HD-ZIP homeobox family. Class II subfamily. (284 aa)
RD29ALow-temperature-induced 78 kDa protein; Involved in responses to abiotic stresses. Regulates probably root elongation in cold conditions ; Belongs to the LTI78/LTI65 family. (710 aa)
ANL2Homeobox-leucine zipper protein ANTHOCYANINLESS 2; Probable transcription factor involved in the regulation of the tissue-specific accumulation of anthocyanins and in cellular organization of the primary root. (802 aa)
ATHB-8Homeobox-leucine zipper protein ATHB-8; Probable transcription factor involved in the regulation of vascular development. May promote differentiation of precambial and cambial cells. (833 aa)
HDG4Homeobox-leucine zipper protein HDG4; Probable transcription factor; Belongs to the HD-ZIP homeobox family. Class IV subfamily. (709 aa)
ATHB-13Homeobox-leucine zipper protein ATHB-13; Probable transcription factor that may act in the sucrose- signaling pathway. (294 aa)
ATML1Homeobox-leucine zipper protein MERISTEM L1; Probable transcription factor involved in cell specification and pattern formation during embryogenesis. Binds to the L1 box DNA sequence 5'-TAAATG[CT]A-3'. Plays a role in maintaining the identity of L1 cells, possibly by interacting with their L1 box or other target- gene promoters. Functionally redundant to PDF2. (762 aa)
NAC072NAC domain-containing protein 72; Transcription factors that bind specifically to the 5'- CATGTG-3' motif. (297 aa)
ACT2Actin-2; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the vegetative actins. (377 aa)
NAC019NAC domain-containing protein 19; Transcription factors that bind specifically to the 5'- CATGTG-3' motif. (317 aa)
HDG5Homeobox-leucine zipper protein HDG5; Probable transcription factor. (826 aa)
CDC73Protein CDC73 homolog; Component of the PAF1 complex (PAF1C) which is involved in histone modifications such as methylation on histone H3 'Lys-4' (H3K4me3). Involved in regulation of flowering time. Required for the expression of the flowering repressors FLC and MADS- box genes of the MAF family. Required for histone H3 trimethylation on 'Lys-4' (H3K4me3) at the FLC locus. Prevents trimethylation on 'Lys-27' (H3K27me3) at the same locus. (415 aa)
NCED39-cis-epoxycarotenoid dioxygenase NCED3, chloroplastic; Has a 11,12(11',12') 9-cis epoxycarotenoid cleavage activity. Catalyzes the first step of abscisic-acid biosynthesis from carotenoids, in response to water stress. (599 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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