STRINGSTRING
RLP1 RLP1 TUFA-2 TUFA-2 METK3 METK3 NHL10 NHL10 SUR1 SUR1 LRR1 LRR1 CDC73 CDC73 RLP30 RLP30 CERK1 CERK1 EFR EFR F22D22.11 F22D22.11 LYK5 LYK5 LYM2 LYM2 UGT74B1 UGT74B1 APK2 APK2 MYB51 MYB51 CYP79B2 CYP79B2 TUFA TUFA CYP79B3 CYP79B3 LYM1 LYM1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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RLP1Receptor-like protein 1; Involved in plant defense. Confers resistance to the bacterial pathogen Xanthomonas through recognition of the microbe- associated molecular pattern (MAMP) eMax. Functionality seems to depend on the presence of the receptor kinase SOBIR1 as an adapter protein. Belongs to the RLP family. (1077 aa)
TUFA-2Elongation factor Tu, mitochondrial; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (454 aa)
METK3S-adenosylmethionine synthase 3; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate. Involved in the biosynthesis of lignin ; Belongs to the AdoMet synthase family. (390 aa)
NHL10NDR1/HIN1-like protein 10; May play a role in plant immunity. (227 aa)
SUR1S-alkyl-thiohydroximate lyase SUR1; C-S lyase involved in glucosinolate biosynthesis. Converts S- (alkylacetohydroximoyl)-L-cysteine to thiohydroximate. Functions in auxin homeostasis. Probably required for glucosinolate activation in response to pathogens; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. (462 aa)
LRR1Leucine-rich repeat protein 1; Involved in plant defense response. (218 aa)
CDC73Protein CDC73 homolog; Component of the PAF1 complex (PAF1C) which is involved in histone modifications such as methylation on histone H3 'Lys-4' (H3K4me3). Involved in regulation of flowering time. Required for the expression of the flowering repressors FLC and MADS- box genes of the MAF family. Required for histone H3 trimethylation on 'Lys-4' (H3K4me3) at the FLC locus. Prevents trimethylation on 'Lys-27' (H3K27me3) at the same locus. (415 aa)
RLP30Receptor-like protein 30; Receptor for microbe-associated molecular patterns (MAMPs) that induces a BAK1-dependent basal immune response to necrotrophic fungi (e.g. S.sclerotiorum) in the presence of MAMPs (e.g. flg22 and SCLEROTINIA CULTURE FILTRATE ELICITOR1 (SCFE1) from the necrotrophic fungal pathogen S. sclerotiorum). Functionality seems to depend on the presence of the receptor kinase SOBIR1 as an adapter protein. Required for full non-host resistance to bacterial pathogens (e.g. P.syringae pv phaseolicola). Belongs to the RLP family. (786 aa)
CERK1Chitin elicitor receptor kinase 1; Lysin motif (LysM) receptor kinase that functions as a cell surface receptor in chitin elicitor (chitooligosaccharides) signaling leading to innate immunity toward both biotic and abiotic stresses (e.g. tolerance to salinity, heavy-metal stresses, and Botrytis cinerea infection). Recognizes microbe-derived N-acetylglucosamine (NAG)- containing ligands. Involved in the resistance to pathogenic fungi Alternaria brassicicola and Erysiphe cichoracearum, probably by sensing microbe-associated molecular patterns (MAMP) and pathogen-associated molecular patt [...] (617 aa)
EFRLRR receptor-like serine/threonine-protein kinase EFR; Constitutes the pattern-recognition receptor (PPR) that determines the specific perception of elongation factor Tu (EF-Tu), a potent elicitor of the defense response to pathogen-associated molecular patterns (PAMPs). Reduces transformation by Rhizobium radiobacter probably by inducing plant defense during the interaction. Binding to the effector AvrPto1 from P.syringae blocks the downstream plant immune response while interaction with hopD2 decreases the phosphorylation level of EFR upon elf18 treatment. Specific endoplasmic reticu [...] (1031 aa)
F22D22.11Transmembrane receptor. (353 aa)
LYK5Protein LYK5; May recognize microbe-derived N-acetylglucosamine (NAG)- containing ligands; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (664 aa)
LYM2LysM domain-containing GPI-anchored protein 2; Chitin elicitor-binding protein involved in the perception of chitin oligosaccharide elicitor. (350 aa)
UGT74B1UDP-glycosyltransferase 74B1; Involved in the biosynthesis of glucosinolate. In in vitro assay, may use phenylacetothiohydroximate (PATH), but not phenylacetic acid (PAA), indole-3-acetic acid (IAA) or salicylic acid (SA) as substrate. Specific for the thiohydroximate functional group and does not glucosylate the carboxylate group or a hydroxyl group. (460 aa)
APK2Adenylyl-sulfate kinase 2, chloroplastic; Catalyzes the synthesis of activated sulfate. Essential for plant reproduction and viability. Required for the production of glucosinolates. Belongs to the APS kinase family. (293 aa)
MYB51Transcription factor MYB51; Transcription factor positively regulating indolic glucosinolate biosynthetic pathway genes. (352 aa)
CYP79B2Tryptophan N-monooxygenase 1; Converts tryptophan to indole-3-acetaldoxime, a precursor for tryptophan-derived glucosinolates and indole-3-acetic acid (IAA). Involved in the biosynthetic pathway to 4-hydroxyindole-3-carbonyl nitrile (4-OH-ICN), a cyanogenic metabolite required for inducible pathogen defense. Belongs to the cytochrome P450 family. (541 aa)
TUFAElongation factor Tu, chloroplastic; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (476 aa)
CYP79B3Tryptophan N-monooxygenase 2; Converts tryptophan to indole-3-acetaldoxime, a precursor for tryptophan derived glucosinolates and indole-3-acetic acid (IAA). Belongs to the cytochrome P450 family. (543 aa)
LYM1LysM domain-containing GPI-anchored protein 1; Required as a cell surface receptor for peptidoglycan (PGN) elicitor signaling leading to innate immunity. Plays an essential role in detecting PGNs and restricting bacterial growth (of Pseudomonas syringae pv. tomato DC3000 for example). (416 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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