STRINGSTRING
STR16 STR16 BHLH14 BHLH14 EIN3 EIN3 MYC4 MYC4 JAZ7 JAZ7 RBCS-3B RBCS-3B CAT2 CAT2 LOX2 LOX2 petA petA SINAT1 SINAT1 MYC2 MYC2 TIFY6A TIFY6A RPN9B RPN9B TIFY5A TIFY5A DOF2.1 DOF2.1 TCP4 TCP4 SINAT6 SINAT6 ACT2 ACT2 WRKY57 WRKY57 MYC3 MYC3 SAG12 SAG12 SWEET15 SWEET15 PUB44 PUB44 BHLH13 BHLH13 BHLH28 BHLH28 SINAT2 SINAT2 EIN2 EIN2 ATG13A ATG13A EIL1 EIL1 PUB13 PUB13 AFPH2 AFPH2 F7A19.29 F7A19.29 AIB AIB PUB12 PUB12 SAG13 SAG13
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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co-expression
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STR16Thiosulfate sulfurtransferase 16, chloroplastic; Thought to act during the early stages of leaf senescence. Catalyzes the transfer of a sulfur ion from a donor to cyanide or to other thiol compounds. Substrate preference is thiosulfate > 3- mercaptopyruvate. (120 aa)
BHLH14Transcription factor bHLH14. (423 aa)
EIN3Protein ETHYLENE INSENSITIVE 3; Probable transcription factor acting as a positive regulator in the ethylene response pathway. Is required for ethylene responsiveness in adult plant tissues. Binds a primary ethylene response element present in the ETHYLENE-RESPONSE-FACTOR1 promoter with consequence to activate the transcription of this gene. (628 aa)
MYC4Transcription factor MYC4; Transcription factor involved in jasmonic acid (JA) gene regulation. With MYC2 and MYC3, controls additively subsets of JA- dependent responses. Can form complexes with all known glucosinolate- related MYBs to regulate glucosinolate biosynthesis. Binds to the G-box (5'-CACGTG-3') of promoters. Activates multiple TIFY/JAZ promoters. (589 aa)
JAZ7Protein TIFY 5B; Repressor of jasmonate responses. (148 aa)
RBCS-3BRibulose bisphosphate carboxylase small chain 3B, chloroplastic; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site (By similarity). (181 aa)
CAT2Catalase-2; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide; Belongs to the catalase family. (492 aa)
LOX2Lipoxygenase 2, chloroplastic; 13S-lipoxygenase that can use linolenic acid as substrates. Plant lipoxygenases may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure. Required for the wound-induced synthesis of jasmonic acid (JA) in leaves. (896 aa)
petACytochrome f; Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. (320 aa)
SINAT1Putative E3 ubiquitin-protein ligase SINAT1; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It probably triggers the ubiquitin-mediated degradation of different substrates (Probable). Mediates the proteasomal-dependent degradation of ATG6, a component of the autophagosome complex. Requires TRAF1A/MUSE14 and TRAF1B/MUSE13 to target ATG6 for ubiquitina [...] (305 aa)
MYC2Transcription factor MYC2; Transcriptional activator. Common transcription factor of light, abscisic acid (ABA), and jasmonic acid (JA) signaling pathways. With MYC3 and MYC4, controls additively subsets of JA-dependent responses. In cooperation with MYB2 is involved in the regulation of ABA-inducible genes under drought stress conditions. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the MYC recognition site (5'-CACATG-3'), and to the G-box (5'-CACNTG-3') and Z-box (5'-ATACGTGT-3') of promoters. Binds directly to the prom [...] (623 aa)
TIFY6AProtein TIFY 6A; Repressor of jasmonate responses. Belongs to the TIFY/JAZ family. (310 aa)
RPN9B26S proteasome non-ATPase regulatory subunit 13 homolog B; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (386 aa)
TIFY5AProtein TIFY 5A; Repressor of jasmonate responses. Unable to associate strongly with COI1 in the presence of jasmonoyl-isoleucine (JA-Ile) and is therefore more resistant to JA-mediated-degradation than other TIFY/JAZ proteins. Repress gene expression through direct recruitment of the corepressor TOPLESS to cognate transcription factors. (131 aa)
DOF2.1Dof zinc finger protein DOF2.1; Transcription factor that binds specifically to a 5'-AA[AG]G- 3' consensus core sequence. (288 aa)
TCP4Transcription factor TCP4; Transcription factor playing a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes, probably through the induction of miRNA (e.g. miR164). Required during early steps of embryogenesis. Participates in ovule develpment. Activates LOX2 expression by binding to the 5'-GGACCA-3' motif found in its promoter. (420 aa)
SINAT6Probable inactive E3 ubiquitin-protein ligase SINAT6; Probable inactive E3 ubiquitin-protein ligase that plays a role in regulation of autophagy. Upon starvation, involved in maintaining ATG6 homeostasis by competitively associating with ATG6, a component of the autophagosome complex. Acts as positive regulator of drought stress response. Functions as positive regulator of abscisic acid-mediated stomatal closure. Belongs to the SINA (Seven in absentia) family. (216 aa)
ACT2Actin-2; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the vegetative actins. (377 aa)
WRKY57Probable WRKY transcription factor 57; Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis- acting element (By similarity); Belongs to the WRKY group II-c family. (287 aa)
MYC3Transcription factor MYC3; Transcription factor involved in tryptophan, jasmonic acid (JA) and other stress-responsive gene regulation. With MYC2 and MYC4, controls additively subsets of JA-dependent responses. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the G-box (5'-CACGTG-3') of promoters. Activates multiple TIFY/JAZ promoters. (592 aa)
SAG12Senescence-specific cysteine protease SAG12; Cysteine protease that may have a developmental senescence specific cell death function during apoptosis, heavy metal detoxification, and hypersensitive response. (346 aa)
SWEET15Bidirectional sugar transporter SWEET15; Mediates both low-affinity uptake and efflux of sugar across the plasma membrane. Regulates cell viability under high salinity. Promotes senescence and sensitivity to salt stress. Contributes to seed filling by triggering sucrose efflux involved in the transfer of sugars from seed coat to embryos. (292 aa)
PUB44U-box domain-containing protein 44; Functions as an E3 ubiquitin-protein ligase. Prevents premature senescence probably by targeting proteins involved in this process for degradation. Promotes the degradation of AAO3 and thus represses abscisic acid (ABA) biosynthesis. (801 aa)
BHLH13Transcription factor bHLH13. (590 aa)
BHLH28Transcription factor bHLH28. (511 aa)
SINAT2E3 ubiquitin-protein ligase SINAT2; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. It probably triggers the ubiquitin-mediated degradation of different substrates (Probable). Mediates the proteasomal-dependent degradation of ATG6, a component of the autophagosome complex. Requires TRAF1A/MUSE14 and TRAF1B/MUSE13 to target ATG6 for ubiquitination and s [...] (308 aa)
EIN2Ethylene-insensitive protein 2; Central factor in signaling pathways regulated by ethylene (ET), and involved in various processes including development, plant defense, senescence, nucleotide sugar flux, and tropisms. Necessary for ethylene-mediated gene regulation, and for the induction of some genes by ozone. Acts downstream of ET receptors, and upstream of ethylene regulated transcription factors. Required for cytokinin-mediated processes. Seems to be implicated in cross-talk between ET, jasmonate and other pathways. Probably not involved in iron uptake. Has a short half-life and un [...] (1294 aa)
ATG13AAutophagy-related protein 13a; Involved in autophagy in a nutritional condition dependent manner. The ATG1-ATG13 protein kinase complex regulates downstream events required for autophagosome enclosure and/or vacuolar delivery. Becomes a target of autophagy under nutrient starvation. Connects autophagy to plant nutritional status. (603 aa)
EIL1ETHYLENE INSENSITIVE 3-like 1 protein; Probable transcription factor acting as a positive regulator in the ethylene response pathway. Could bind the primary ethylene response element present in the ETHYLENE-RESPONSE-FACTOR1 promoter. Belongs to the EIN3 family. (584 aa)
PUB13U-box domain-containing protein 13; Functions as an E3 ubiquitin ligase. (660 aa)
AFPH2AFP homolog 2; Acts as a transcriptional repressor. Negative regulator of jasmonate responses. Connects the JAZ proteins and the non-JAZ protein TIFY8 with the TOPLESS corepressors; Belongs to the Ninja family. (425 aa)
F7A19.29RING/U-box superfamily protein. (179 aa)
AIBTranscription factor ABA-INDUCIBLE bHLH-TYPE; Transcription activator. Regulates positively abscisic acid (ABA) response. Confers drought tolerance and sensitivity to ABA. (566 aa)
PUB12U-box domain-containing protein 12; Functions as an E3 ubiquitin ligase. (654 aa)
SAG13Senescence-associated protein 13; Unspecific reductase providing both diastereomeric alcohols from the prochiral ketones. Active on cyclic monoterpenes and small flexible lipophilic carbonyls. No activity with tropinone, nitrogen- containing tropinone analogs, tropine or pseudotropine as substrate. (269 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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