STRINGSTRING
HSFA2 HSFA2 FGT1 FGT1 CHR17 CHR17 APX2 APX2 TSK TSK CHR11 CHR11 REF6 REF6
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second shell of interactors
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HSFA2Heat stress transcription factor A-2; Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). Involved in heat stress responses. Seems to be involved in other environmental stress responses. Activates ascorbate peroxidase 2 (APX2) in addition to several heat shock protein (HSPs). Belongs to the HSF family. Class A subfamily. (345 aa)
FGT1Protein FORGETTER 1; Required for normal embryo development. Necessary to acquire heat stress (HS) memory, by modulating nucleosome occupancy and regulating heat-induced gene expression. Associates globally with the nucleosome-poor regions flanking the transcription units of expressed genes. Binds to the promoter regions, primarily to the proximal promoter just upstream of the transcriptional start sites (TSS) and somewhat more weakly to the region downstream of the transcription termination site (TTS), of actively expressed genes (e.g. HSA32, HSP18.2 and HSP22.0) in a heat- dependent [...] (1295 aa)
CHR17ISWI chromatin-remodeling complex ATPase CHR17; Possesses intrinsic ATP-dependent nucleosome-remodeling activity. Constitutes the catalytic subunit of several complexes capable of forming ordered nucleosome arrays on chromatin (By similarity). Involved in the formation of nucleosome distribution patterns. Required for the maintenance of the plant vegetative phase. In association with RLT1 or RLT2 may prevent the early activation of the vegetative-to-reproductive transition by regulating key genes that contribute to flower timing, such as FT, SEP1, SEP3, AGL8/FUL, SOC1 and FLC. Necessar [...] (1069 aa)
APX2L-ascorbate peroxidase 2, cytosolic; Plays a key role in hydrogen peroxide removal. (251 aa)
TSKProtein TONSOKU; Required for cell arrangement in root and shoot apical meristems. Involved in structural and functional stabilization of chromatin and may represent a link between response to DNA damage and epigenetic gene silencing. May be involved, when interacting with TSA1, in the organization of spindle microtubules. Belongs to the Tonsoku family. (1311 aa)
CHR11ISWI chromatin-remodeling complex ATPase CHR11; Possesses intrinsic ATP-dependent nucleosome-remodeling activity. Constitutes the catalytic subunit of several complexes capable of forming ordered nucleosome arrays on chromatin (By similarity). Involved in the formation of nucleosome distribution patterns. Involved in nuclear proliferation during megagametogenesis and cell expansion in the sporophyte. Required for the maintenance of the plant vegetative phase. In association with RLT1 or RLT2 may prevent the early activation of the vegetative-to-reproductive transition by regulating key [...] (1056 aa)
REF6Lysine-specific demethylase REF6; Histone demethylase that demethylates 'Lys-27' (H3K27me) of histone H3. Demethylates both tri- (H3K27me3) and di-methylated (H3K27me2) H3K27me. Demethylates also H3K4me3/2 and H3K36me3/2 in an in vitro assay. Involved in the transcriptional regulation of hundreds of genes regulating developmental patterning and responses to various stimuli. Binds DNA via its four zinc fingers in a sequence- specific manner, 5'-CTCTGYTY-3', to promote the demethylation of H3K27me3 and the regulation of organ boundary formation. Involved in the regulation of flowering ti [...] (1360 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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