STRINGSTRING
PRORP3 PRORP3 MED12 MED12 KNAT1 KNAT1 PRORP1 PRORP1 PRORP2 PRORP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
PRORP3Proteinaceous RNase P 3; Endonuclease RNase P responsible for the 5' maturation of tRNA precursors. Also involved in the maturation of mRNA and small nucleolar RNA (snoRNA); Belongs to the PPR family. P subfamily. (576 aa)
MED12Mediator of RNA polymerase II transcription subunit 12; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general [...] (2235 aa)
KNAT1Homeobox protein knotted-1-like 1; May play a role in meristem function, and may be involved in maintaining cells in an undifferentiated, meristematic state, and its expression disappears at the same time the shoot apex undergoes the transition from vegetative to reproductive development. Positive regulator of LATERAL ORGAN BOUNDARIES (LOB). Probably binds to the DNA sequence 5'-TGAC-3'. Able to traffic from the L1 to the L2/L3 layers of the meristem, presumably through plasmodesmata. Belongs to the TALE/KNOX homeobox family. (398 aa)
PRORP1Proteinaceous RNase P 1, chloroplastic/mitochondrial; Endonuclease RNase P responsible for the 5' maturation of tRNA precursors. Preferentially cleaves at the unusual cleavage site, but also able to cleave at the classical cleavage site. Also involved in the maturation of mRNAs in mitochondria. (572 aa)
PRORP2Proteinaceous RNase P 2; Endonuclease RNase P responsible for the 5' maturation of tRNA precursors. Preferentially binds precursor tRNAs containing short 5' leaders and 3' trailers. Also involved in the maturation of mRNA and small nucleolar RNA (snoRNA) ; Belongs to the PPR family. P subfamily. (528 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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