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HDG11 HDG11 CDA1 CDA1 ACT1 ACT1 HAT3 HAT3 HAT22 HAT22 GL2 GL2 HAT14 HAT14 ATHB-5 ATHB-5 ATHB-6 ATHB-6 ATHB-7 ATHB-7 AP2 AP2 HAT5 HAT5 HAT4 HAT4 HDG4 HDG4 ATML1 ATML1 ATHB-16 ATHB-16 ZIP11 ZIP11 ATHB-12 ATHB-12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HDG11Homeobox-leucine zipper protein HDG11; Transcription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA. Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth. Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects r [...] (722 aa)
CDA1Cytidine deaminase 1; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. Functions as a conventional cytidine deaminase. Has no affinity for RNA and is not involved in RNA- editing by C-to-U deamination. (301 aa)
ACT1Actin-1; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the reproductive actins. (377 aa)
HAT3Homeobox-leucine zipper protein HAT3; Probable transcription factor. (315 aa)
HAT22Homeobox-leucine zipper protein HAT22; Probable transcription factor. (278 aa)
GL2Homeobox-leucine zipper protein GLABRA 2; Probable transcription factor required for correct morphological development and maturation of trichomes as well as for normal development of seed coat mucilage. Regulates the frequency of trichome initiation and determines trichome spacing. (747 aa)
HAT14Homeobox-leucine zipper protein HAT14; Probable transcription factor. (336 aa)
ATHB-5Homeobox-leucine zipper protein ATHB-5; Probable transcription factor that acts as a positive regulator of ABA-responsiveness, mediating the inhibitory effect of ABA on growth during seedling establishment. Binds to the DNA sequence 5'- CAATNATTG-3'. (312 aa)
ATHB-6Homeobox-leucine zipper protein ATHB-6; Transcription activator that may act as growth regulators in response to water deficit. Interacts with the core sequence 5'- CAATTATTA-3' of promoters in response to ABA and in an ABI1-dependent manner. Involved in the negative regulation of the ABA signaling pathway; Belongs to the HD-ZIP homeobox family. Class I subfamily. (311 aa)
ATHB-7Homeobox-leucine zipper protein ATHB-7; Probable transcription activator that may act as growth regulators in response to water deficit. (258 aa)
AP2Floral homeotic protein APETALA 2; Probable transcriptional activator that promotes early floral meristem identity. Is required subsequently for the transition of an inflorescence meristem into a floral meristem. Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower, by spatially controlling the expression domains of multiple floral organ identity genes. Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in association with other repressors like LEUNIG and [...] (432 aa)
HAT5Homeobox-leucine zipper protein HAT5; Probable transcription activator involved in leaf development. Binds to the DNA sequence 5'-CAAT[AT]ATTG-3'. Belongs to the HD-ZIP homeobox family. Class I subfamily. (272 aa)
HAT4Homeobox-leucine zipper protein HAT4; Probable transcription factor involved in the negative regulation of cell elongation and specific cell proliferation processes such as lateral root formation and secondary growth of the vascular system. Acts as mediator of the red/far-red light effects on leaf cell expansion in the shading response. Binds to the DNA sequence 5'- CAAT[GC]ATTG-3'. Negatively regulates its own expression. Belongs to the HD-ZIP homeobox family. Class II subfamily. (284 aa)
HDG4Homeobox-leucine zipper protein HDG4; Probable transcription factor; Belongs to the HD-ZIP homeobox family. Class IV subfamily. (709 aa)
ATML1Homeobox-leucine zipper protein MERISTEM L1; Probable transcription factor involved in cell specification and pattern formation during embryogenesis. Binds to the L1 box DNA sequence 5'-TAAATG[CT]A-3'. Plays a role in maintaining the identity of L1 cells, possibly by interacting with their L1 box or other target- gene promoters. Functionally redundant to PDF2. (762 aa)
ATHB-16Homeobox-leucine zipper protein ATHB-16; Probable transcription factor that may function as a negative regulator of the flowering time response to photoperiod. May act to repress cell expansion during plant development. (294 aa)
ZIP11Zinc transporter 11; Probably mediates zinc uptake from the rhizosphere. Belongs to the ZIP transporter (TC 2.A.5) family. (326 aa)
ATHB-12Homeobox-leucine zipper protein ATHB-12; Probable transcription activator that may act as growth regulators in response to water deficit. (235 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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