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nad5 nad5 nad2 nad2 cox2 cox2 ccmFC ccmFC nad4 nad4 nad7 nad7 matR matR B3H674_ARATH B3H674_ARATH nad1 nad1 XPO1B XPO1B NDB3 NDB3 F28M20.240 F28M20.240 ND2 ND2 AOX1C AOX1C AOX1B AOX1B EMB1025 EMB1025 CTU2 CTU2 NDA2 NDA2 SAM2 SAM2 PSBO1 PSBO1 ND5 ND5 BCA2 BCA2 COX1 COX1 ND1 ND1 COX2 COX2 CCMFC CCMFC NAD7 NAD7 ND4 ND4 ABI3 ABI3 NDB1 NDB1 AOX1A AOX1A NDA1 NDA1 NDC1 NDC1 AOX3 AOX3 VAR3 VAR3 NDB2 NDB2 MTERF15 MTERF15 F14C21.55 F14C21.55 NMAT1 NMAT1 NMAT4 NMAT4 ABO6 ABO6 RUG3 RUG3 NMAT2 NMAT2 MSJ1.11 MSJ1.11 RAD52-1 RAD52-1 CFM9 CFM9 RH53 RH53 PCR8 PCR8 OTP43 OTP43 NDB4 NDB4 XPO1 XPO1 BIR6 BIR6 ABO5 ABO5 WTF9 WTF9
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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nad5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (669 aa)
nad2NADH dehydrogenase subunit 2. (488 aa)
cox2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (260 aa)
ccmFCCytochrome c biogenesis FC. (442 aa)
nad4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (495 aa)
nad7NADH dehydrogenase subunit 7; Belongs to the complex I 49 kDa subunit family. (394 aa)
matRMaturase. (656 aa)
B3H674_ARATHAlternative NAD(P)H dehydrogenase. (87 aa)
nad1NADH-ubiquinone oxidoreductase chain 1; Belongs to the complex I subunit 1 family. (325 aa)
XPO1BProtein EXPORTIN 1B; Receptor for the leucine-rich nuclear export signal (NES). Binds cooperatively to the NES on its target protein and to the small GTPase Ran in its active GTP-bound form (By similarity). Required for the maternal-to-embryonic transition and during gametophyte development ; Belongs to the exportin family. (1076 aa)
NDB3External alternative NAD(P)H-ubiquinone oxidoreductase B3, mitochondrial; Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane. (580 aa)
F28M20.240Nucleoporin. (2730 aa)
ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (499 aa)
AOX1CUbiquinol oxidase 1c, mitochondrial; Catalyzes the cyanide-resistant oxidation of ubiquinol and the reduction of molecular oxygen to water, but does not translocate protons and consequently is not linked to oxidative phosphorylation. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures (By similarity). Belongs to the alternative oxidase family. (329 aa)
AOX1BUbiquinol oxidase 1b, mitochondrial; Catalyzes the cyanide-resistant oxidation of ubiquinol and the reduction of molecular oxygen to water, but does not translocate protons and consequently is not linked to oxidative phosphorylation. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures (By similarity). Belongs to the alternative oxidase family. (325 aa)
EMB1025Pentatricopeptide repeat-containing protein At4g20090; May play a role in embryogenesis. (660 aa)
CTU2Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. (458 aa)
NDA2Internal alternative NAD(P)H-ubiquinone oxidoreductase A2, mitochondrial; Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane. (508 aa)
SAM2S-adenosylmethionine synthase 2; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate. (393 aa)
PSBO1Oxygen-evolving enhancer protein 1-1, chloroplastic; Stabilizes the manganese cluster which is the primary site of water splitting. (332 aa)
ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (669 aa)
BCA2Beta carbonic anhydrase 2, chloroplastic; Reversible hydration of carbon dioxide. This isoform ensures the supply of bicarbonate for pep carboxylase; Belongs to the beta-class carbonic anhydrase family. (331 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (527 aa)
ND1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (325 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (260 aa)
CCMFCCytochrome c biogenesis CcmF C-terminal-like mitochondrial protein; Forms a complex with CCMFN1, CCMFN2 and CCMH that performs the assembly of heme with c-type apocytochromes in mitochondria. Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family. (442 aa)
NAD7NADH dehydrogenase [ubiquinone] iron-sulfur protein 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). Component of the iron-sulfur (IP) fragment of the enzyme. (394 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (495 aa)
ABI3B3 domain-containing transcription factor ABI3; Participates in abscisic acid-regulated gene expression during seed development. Regulates the transcription of SGR1 and SGR2 that are involved in leaf and embryo degreening. (720 aa)
NDB1External alternative NAD(P)H-ubiquinone oxidoreductase B1, mitochondrial; Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane (By similarity). Calcium-dependent NAD(P)H dehydrogenase. Binds calcium ions. (571 aa)
AOX1AUbiquinol oxidase 1a, mitochondrial; Catalyzes the cyanide-resistant oxidation of ubiquinol and the reduction of molecular oxygen to water, but does not translocate protons and consequently is not linked to oxidative phosphorylation. Increases respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures. (354 aa)
NDA1Internal alternative NAD(P)H-ubiquinone oxidoreductase A1, mitochondrial; Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane. (510 aa)
NDC1Alternative NAD(P)H-ubiquinone oxidoreductase C1, chloroplastic/mitochondrial; Bifunctional oxidoreductase ables to act both on prenyl naphthoquinones and on prenyl benzoquinones. May serve a respiratory function. Involved in an electron flow toward the plastoglobule plastoquinone pool. Required for plastochromanol-8 accumulation and for phylloquinone (vitamin K1) production. Probably not directly involved in cyclic or chlororespiratory electron flows under standard growth conditions, but participates in the redox metabolism of plastoquinone-9 and the tocophrol recycling-intermediate a [...] (519 aa)
AOX3Ubiquinol oxidase 3, mitochondrial; Catalyzes the cyanide-resistant oxidation of ubiquinol and the reduction of molecular oxygen to water, but does not translocate protons and consequently is not linked to oxidative phosphorylation. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures (By similarity). (318 aa)
VAR3Zinc finger protein VAR3, chloroplastic; Probable component of some protein complex required for chloroplast and palisade cell development. Involved in C-to-U editing of chloroplastic RNA. Controls a large number of chloroplastic editing sites. Binds the editing recognition trans- factors PCMP-H51/CRR28 and PCMP-H12/OTP82. (758 aa)
NDB2External alternative NAD(P)H-ubiquinone oxidoreductase B2, mitochondrial; Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane (By similarity). Calcium-dependent NAD(P)H dehydrogenase; more efficient on NADH. Binds calcium ions. (582 aa)
MTERF15Transcription termination factor MTERF15, mitochondrial; Transcription termination factor required for mitochondrial NAD2 intron 3 splicing and normal membrane respiratory chain Complex I activity. Essential for normal plant growth and development. Binds to RNA but not to double-stranded DNA. (445 aa)
F14C21.55Zinc finger (Ran-binding) family protein. (849 aa)
NMAT1Nuclear intron maturase 1, mitochondrial; Nuclear-encoded maturase required for splicing of group-II introns in mitochondria. Necessary for mitochondrial biogenesis during early developmental stages. Involved in the splicing of mitochondrial NAD4 transcripts. Required for trans-splicing of NAD1 intron 1 and also functions in cis-splicing of NAD2 intron 1 and NAD4 intron 2. Required for the regulation of fundamental metabolic pathways such as amino acid metabolism, triacylglycerol degradation and polysaccharide synthesis (cellulose and starch) during the early stage of plant growth. Imp [...] (711 aa)
NMAT4Nuclear intron maturase 4, mitochondrial; Nuclear-encoded maturase required for splicing of group-II introns in mitochondria. Involved in NAD1 pre-mRNA processing and maturation of introns 1, 3 and 4. Necessary for mitochondrial biogenesis during early developmental stages. Essential for respiratory holocomplex I biogenesis in mitochondria. (798 aa)
ABO6ATP-dependent RNA helicase A-like protein. (1161 aa)
RUG3RCC1 domain-containing protein RUG3, mitochondrial; Regulates DNA damage response (DDR) synergistically with ATM. Together with ATM, involved in the splicing of the ND2/NAD2 mRNA. Required for the accumulation of mitochondrial respiratory chain complex I. Negative regulator of plant responses to abscisic acid (ABA). May have a pivotal role in vegetative growth and the phase transition from vegetative to reproductive growth. (445 aa)
NMAT2Nuclear intron maturase 2, mitochondrial; Nuclear-encoded maturase required for splicing of group-II introns in mitochondria. Involved in the splicing of mitochondrial COX2, NAD1 and NAD7 transcripts. Necessary for mitochondrial biogenesis during early developmental stages. (735 aa)
MSJ1.11Nuclear protein-like. (1269 aa)
RAD52-1DNA repair RAD52-like protein 1, mitochondrial; Plant-specific single-stranded DNA-binding protein required for efficient heterologous recombination-dependent DNA repair in nuclear and mitochondrial compartments. Forms large nucleo-protein complexes with WHY2 in mitochondria. Binds ssDNA with high affinity, but with little sequence specificity. Involved in double-stranded DNA break repair. Involved in the hydrolytic splicing pathway in mitochondrion. Facilitates the excision of two cis-spliced group II introns, NAD1 intron 2 and NAD2 intron 1 ; Belongs to the RAD52 family. (176 aa)
CFM9CRM-domain containing factor CFM9, mitochondrial; Involved in the splicing of group II introns in mitochondria. Required for the splicing of mitochondrial introns found in nad1, nad2, nad4, nad5, nad7, rps3 and cox2 genes. Splicing of mitochondrial introns is crucial for mitochondrial biogenesis and function, plant growth and development, and plant response to abiotic stresses. (491 aa)
RH53DEAD-box ATP-dependent RNA helicase 53, mitochondrial. (616 aa)
PCR8Protein PLANT CADMIUM RESISTANCE 8; May be involved in heavy metals transport; Belongs to the cornifelin family. (190 aa)
OTP43Pentatricopeptide repeat-containing protein At1g74900, mitochondrial; Required for the trans-splicing of intron 1 of the mitochondrial nad1 transcript encoding the ND1 subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). (482 aa)
NDB4External alternative NAD(P)H-ubiquinone oxidoreductase B4, mitochondrial; Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane (By similarity). NAD(P)H dehydrogenase; more efficient on NADH. (582 aa)
XPO1Protein EXPORTIN 1A; Receptor for the leucine-rich nuclear export signal (NES). Binds cooperatively to the NES on its target protein and to the small GTPase Ran in its active GTP-bound form. Required for the maternal-to-embryonic transition and during gametophyte development. Involved in heat- induced oxidative stress basal resistance. Belongs to the exportin family. (1075 aa)
BIR6Pentatricopeptide repeat-containing protein At3g48250, chloroplastic. (621 aa)
ABO5Pentatricopeptide repeat-containing protein At1g51965, mitochondrial. (650 aa)
WTF9Protein WHAT'S THIS FACTOR 9, mitochondrial; RNA-binding protein involved in group II intron splicing. Binds specific group II introns and promotes their splicing (e.g. rpl2 and ccmFC). (387 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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