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FIO1 | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; Belongs to the methyltransferase superfamily. METTL16/RlmF family. (513 aa) | ||||
VCR | Varicose-related protein; As a component of the decapping complex, may play a role in the degradation of mRNAs. (1340 aa) | ||||
HAKAI | E3 ubiquitin-protein ligase HAKAI homolog; Probable E3 ubiquitin-protein ligase which is a subunit of the N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation at the 5'-[AG]GAC-3' consensus sites of some mRNAs. Associates with MTA, MTB, FIP37 and VIR to form the m6A writer complex which is essential for adenosine methylation at specific mRNA sequences. N6- methyladenosine (m6A) plays a role in mRNA stability, processing, translation efficiency and editing. (360 aa) |