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RUG3 RUG3 NMAT2 NMAT2 MSJ1.11 MSJ1.11 RAD52-1 RAD52-1 TMN11 TMN11 GBSS1 GBSS1 WTF9 WTF9 ccmFC ccmFC nad4 nad4 rpl2 rpl2 WTF1 WTF1 NDB3 NDB3 NDA2 NDA2 rpl2-A rpl2-A RPL2 RPL2 ND4 ND4 NDB1 NDB1 SUP SUP T3H13.12 T3H13.12 NDA1 NDA1 NDC1 NDC1 NDB2 NDB2 MTERF15 MTERF15 NMAT1 NMAT1 NMAT4 NMAT4
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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RUG3RCC1 domain-containing protein RUG3, mitochondrial; Regulates DNA damage response (DDR) synergistically with ATM. Together with ATM, involved in the splicing of the ND2/NAD2 mRNA. Required for the accumulation of mitochondrial respiratory chain complex I. Negative regulator of plant responses to abscisic acid (ABA). May have a pivotal role in vegetative growth and the phase transition from vegetative to reproductive growth. (445 aa)
NMAT2Nuclear intron maturase 2, mitochondrial; Nuclear-encoded maturase required for splicing of group-II introns in mitochondria. Involved in the splicing of mitochondrial COX2, NAD1 and NAD7 transcripts. Necessary for mitochondrial biogenesis during early developmental stages. (735 aa)
MSJ1.11Nuclear protein-like. (1269 aa)
RAD52-1DNA repair RAD52-like protein 1, mitochondrial; Plant-specific single-stranded DNA-binding protein required for efficient heterologous recombination-dependent DNA repair in nuclear and mitochondrial compartments. Forms large nucleo-protein complexes with WHY2 in mitochondria. Binds ssDNA with high affinity, but with little sequence specificity. Involved in double-stranded DNA break repair. Involved in the hydrolytic splicing pathway in mitochondrion. Facilitates the excision of two cis-spliced group II introns, NAD1 intron 2 and NAD2 intron 1 ; Belongs to the RAD52 family. (176 aa)
TMN11Transmembrane 9 superfamily member 11. (658 aa)
GBSS1Granule-bound starch synthase 1, chloroplastic/amyloplastic; Required for the synthesis of amylose. Destroyed as it is released from the starch granules during the night. The circadian expression is controlled by CCA1 and LHY transcription factors. (610 aa)
WTF9Protein WHAT'S THIS FACTOR 9, mitochondrial; RNA-binding protein involved in group II intron splicing. Binds specific group II introns and promotes their splicing (e.g. rpl2 and ccmFC). (387 aa)
ccmFCCytochrome c biogenesis FC. (442 aa)
nad4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (495 aa)
rpl2Ribosomal protein L2. (349 aa)
WTF1Protein WHAT'S THIS FACTOR 1 homolog, chloroplastic; RNA-binding protein involved in group II intron splicing. Binds specific group II introns and promotes their splicing. Functions in the context of a heterodimer with the ribonuclease III domain- containing protein RNC1. (528 aa)
NDB3External alternative NAD(P)H-ubiquinone oxidoreductase B3, mitochondrial; Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane. (580 aa)
NDA2Internal alternative NAD(P)H-ubiquinone oxidoreductase A2, mitochondrial; Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane. (508 aa)
rpl2-A50S ribosomal protein L2, chloroplastic; Belongs to the universal ribosomal protein uL2 family. (274 aa)
RPL260S ribosomal protein L2, mitochondrial; Belongs to the universal ribosomal protein uL2 family. (349 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (495 aa)
NDB1External alternative NAD(P)H-ubiquinone oxidoreductase B1, mitochondrial; Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane (By similarity). Calcium-dependent NAD(P)H dehydrogenase. Binds calcium ions. (571 aa)
SUPTranscriptional regulator SUPERMAN; Probable transcriptional regulator considered as cadastral protein that acts indirectly to prevent the B class homeotic proteins APETALA3 and perhaps PISTILLATA from acting in the gynoecial whorl. Principal function is to balance cell proliferation in the third and fourth whorls of developing flowers thereby maintaining the boundary between stamens and carpels. May fulfill this role by repressing genes implicated in cell division. Plays equally a role in the determinacy of the floral meristem. Is also required for normal ovule development. (204 aa)
T3H13.12Ubiquitin carboxyl-terminal hydrolase family protein. (395 aa)
NDA1Internal alternative NAD(P)H-ubiquinone oxidoreductase A1, mitochondrial; Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane. (510 aa)
NDC1Alternative NAD(P)H-ubiquinone oxidoreductase C1, chloroplastic/mitochondrial; Bifunctional oxidoreductase ables to act both on prenyl naphthoquinones and on prenyl benzoquinones. May serve a respiratory function. Involved in an electron flow toward the plastoglobule plastoquinone pool. Required for plastochromanol-8 accumulation and for phylloquinone (vitamin K1) production. Probably not directly involved in cyclic or chlororespiratory electron flows under standard growth conditions, but participates in the redox metabolism of plastoquinone-9 and the tocophrol recycling-intermediate a [...] (519 aa)
NDB2External alternative NAD(P)H-ubiquinone oxidoreductase B2, mitochondrial; Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane (By similarity). Calcium-dependent NAD(P)H dehydrogenase; more efficient on NADH. Binds calcium ions. (582 aa)
MTERF15Transcription termination factor MTERF15, mitochondrial; Transcription termination factor required for mitochondrial NAD2 intron 3 splicing and normal membrane respiratory chain Complex I activity. Essential for normal plant growth and development. Binds to RNA but not to double-stranded DNA. (445 aa)
NMAT1Nuclear intron maturase 1, mitochondrial; Nuclear-encoded maturase required for splicing of group-II introns in mitochondria. Necessary for mitochondrial biogenesis during early developmental stages. Involved in the splicing of mitochondrial NAD4 transcripts. Required for trans-splicing of NAD1 intron 1 and also functions in cis-splicing of NAD2 intron 1 and NAD4 intron 2. Required for the regulation of fundamental metabolic pathways such as amino acid metabolism, triacylglycerol degradation and polysaccharide synthesis (cellulose and starch) during the early stage of plant growth. Imp [...] (711 aa)
NMAT4Nuclear intron maturase 4, mitochondrial; Nuclear-encoded maturase required for splicing of group-II introns in mitochondria. Involved in NAD1 pre-mRNA processing and maturation of introns 1, 3 and 4. Necessary for mitochondrial biogenesis during early developmental stages. Essential for respiratory holocomplex I biogenesis in mitochondria. (798 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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