STRINGSTRING
CERK1 CERK1 JAZ13 JAZ13 WAK1 WAK1 RLK1 RLK1 SAC1 SAC1 TIFY11B TIFY11B TIFY10A TIFY10A TIFY6B TIFY6B EDS1 EDS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CERK1Chitin elicitor receptor kinase 1; Lysin motif (LysM) receptor kinase that functions as a cell surface receptor in chitin elicitor (chitooligosaccharides) signaling leading to innate immunity toward both biotic and abiotic stresses (e.g. tolerance to salinity, heavy-metal stresses, and Botrytis cinerea infection). Recognizes microbe-derived N-acetylglucosamine (NAG)- containing ligands. Involved in the resistance to pathogenic fungi Alternaria brassicicola and Erysiphe cichoracearum, probably by sensing microbe-associated molecular patterns (MAMP) and pathogen-associated molecular patt [...] (617 aa)
JAZ13Protein JAZ13; Non-TIFY functional repressor of jasmonate (JA)-mediated growth and defense responses. Intrinsically resistant to JA-induced turnover, probably due to the absence of the canonical degron that strongly interacts with COI1 in the presence of JA-Ile in the TIFY/JAZ proteins. (125 aa)
WAK1Wall-associated receptor kinase 1; Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. Binding to pectin may have significance in the control of cell expansion, morphogenesis and development. Required during plant's response to pathogen infection and in plant defense against heavy metal toxicity. Phosphorylates the oxygen-evolving enhancer protein 2 (OEE2) in an GRP-3-dependent manner. (735 aa)
RLK1G-type lectin S-receptor-like serine/threonine-protein kinase RLK1. (832 aa)
SAC1Phosphoinositide phosphatase SAC1; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Required for normal cell morphogenesis, cell wall synthesis, and actin organization. (912 aa)
TIFY11BProtein TIFY 11B; Repressor of jasmonate responses. (269 aa)
TIFY10AProtein TIFY 10A; Repressor of jasmonate responses. Jasmonoyl-isoleucine (JA- Ile) specifically promotes COI1-TIFY10A/JAZ1 interaction. Interacts with COI1 and inositol pentakisphosphate to form a high-affinity jasmonates coreceptor. (253 aa)
TIFY6BProtein TIFY 6B; Repressor of jasmonate responses. Jasmonoyl-isoleucine (JA- Ile) specifically promotes COI1-TIFY6B/JAZ3 interaction. Acts as a negative regulator of MYC2 function. Feed-back regulated by MYC2. Belongs to the TIFY/JAZ family. (352 aa)
EDS1Protein EDS1; Positive regulator of basal resistance and of effector- triggered immunity specifically mediated by TIR-NB-LRR (TNL) resistance proteins. Disruption by bacterial effector of EDS1-TIR-NB-LRR resistance protein interactions constitutes the first step in resistance activation. Acts redundantly with salicylic acid to regulate resistance gene-mediated signaling. Triggers early plant defenses and hypersensitive response independently of PAD4, and then recruits PAD4 to potentiate plant defenses through the accumulation of salicylic acid. Nuclear localization is essential for bas [...] (623 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (28%) [HD]