STRINGSTRING
GLV8 GLV8 F4N21.7 F4N21.7 BRI1 BRI1 dl3725w dl3725w BARS1 BARS1 dl3720w dl3720w SBT1.7 SBT1.7 TPS27 TPS27 TPS23 TPS23 AHA2 AHA2 AHA1 AHA1 GAPC1 GAPC1 RGF1 RGF1 TPST TPST RGF7 RGF7 JKD JKD CNGC17 CNGC17 SERK1 SERK1 BAK1 BAK1 MYB23 MYB23 ACT2 ACT2 RLK RLK CRRSP58 CRRSP58 THAS1 THAS1 CYP705A5 CYP705A5 MRN1 MRN1 PSKR2 PSKR2 PSK1 PSK1 EXPA7 EXPA7 WER WER PSK4 PSK4 SBT3.8 SBT3.8 SERK2 SERK2 PSKR1 PSKR1 BHLH129 BHLH129
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GLV8Protein GOLVEN 8; Promotes root hairs formation and growth. Belongs to the RGF family. (111 aa)
F4N21.7NAD(P)-binding Rossmann-fold superfamily protein. (319 aa)
BRI1Protein BRASSINOSTEROID INSENSITIVE 1; Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development, including expression of light- and stress-regulated genes, promotion of cell elongation, normal leaf and chloroplast senescence, and flowering. Binds brassinolide, and less effectively castasterone, but not 2,3,22,23-O-tetramethylbrassinolide or ecdysone. May be involved in a feedback regulation of brassinosteroid biosynthesis. Pho [...] (1196 aa)
dl3725wCytochrome P450, family 705, subfamily A, polypeptide 3; Belongs to the cytochrome P450 family. (527 aa)
BARS1Baruol synthase; Converts oxidosqualene to baruol (90%) and 22 minor products. Belongs to the terpene cyclase/mutase family. (759 aa)
dl3720wCytochrome P450, family 705, subfamily A, polypeptide 2. (509 aa)
SBT1.7Subtilisin-like protease SBT1.7; Serine protease. Has a substrate preference for the hydrophobic residues Phe and Ala and the basic residue Asp in the P1 position, and for Asp, Leu or Ala in the P1' position. Essential for mucilage release from seed coats. Triggers the accumulation and/or activation of cell wall modifying enzymes necessary either for the loosening of the outer primary cell wall, or to facilitate swelling of the mucilage. (757 aa)
TPS271,8-cineole synthase 1, chloroplastic; Involved in monoterpene (C10) biosynthesis. The major product is 1,8-cineole (52%) followed by minor amounts of sabinene (14.5%), myrcene (13.3%), (-)-(1S)-beta-pinene (7.8%), (-)-(4S)-limonene (4.0%), (E)-beta-ocimene (2.7%), alpha-terpineol (2.4%), (-)-(1S)-alpha-pinene (1.9%), terpinolene (0.8%), and (+)-alpha-thujene (0.6%). (600 aa)
TPS231,8-cineole synthase 2, chloroplastic; Involved in monoterpene (C10) biosynthesis. The major product is 1,8-cineole (52%) followed by minor amounts of sabinene (14.5%), myrcene (13.3%), (-)-(1S)-beta-pinene (7.8%), (-)-(4S)-limonene (4.0%), (E)-beta-ocimene (2.7%), alpha-terpineol (2.4%), (-)-(1S)-alpha-pinene (1.9%), terpinolene (0.8%), and (+)-alpha-thujene (0.6%). (600 aa)
AHA2ATPase 2, plasma membrane-type; The plasma membrane H(+) ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses. Involved in maintaining the membrane potential and delta-pH, together forming the plasma membrane protonmotive force (PMF) required for root and hypocotyl elongation and root tropism. Important for root growth and development during different nitrogen regimes. Forms a functional cation-translocating unit with CNGC17 tha [...] (948 aa)
AHA1ATPase 1, plasma membrane-type; The plasma membrane H(+) ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses. Forms a functional cation- translocating unit with CNGC17 that is activated by PSKR1/BAK1 and possibly other BAK1/RLK complexes. (949 aa)
GAPC1Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic; Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3- phospho-D-glyceroyl phosphate. Essential for the maintenance of cellular ATP levels and carbohydrate metabolism. Required for full fertility. Involved in response to oxidative stress by mediating plant responses to abscisic acid (ABA) and water deficits through the activation of PLDDELTA and production of phosphatidic acid (PA), a multifunctional stress signaling lipid in plants. Associates with FBA6 to [...] (338 aa)
RGF1Root meristem growth factor 1; Maintains the postembryonic root stem cell niche by regulating the expression levels and patterns of the transcription factor PLETHORA (PLT), mainly at the post-transcriptional level. Belongs to the RGF family. (116 aa)
TPSTProtein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides. (500 aa)
RGF7Root meristem growth factor 7; Maintains the postembryonic root stem cell niche. Belongs to the RGF family. (102 aa)
JKDZinc finger protein JACKDAW; Transcription factor that, together with BIB, regulates tissue boundaries and asymmetric cell division by a rapid up-regulation of 'SCARECROW' (SCR), thus controlling the nuclear localization of 'SHORT-ROOT' (SHR) and restricting its action. Binds DNA via its zinc fingers. Recognizes and binds to SCL3 promoter sequence 5'- AGACAA-3' to promotes its expression when in complex with RGA. Confines CYCD6 expression to the cortex-endodermis initial/daughter (CEI/CEID) tissues. Required for radial patterning and stem cell maintenance. Counteracted by 'MAGPIE' (MGP [...] (503 aa)
CNGC17Cyclic nucleotide-gated ion channel 17; Probable cyclic nucleotide-gated ion channel. Forms a functional cation-translocating unit with AHAs that is activated by PSKR1/BAK1 and possibly other BAK1/RLK complexes. Required for PSK-induced protoplast expansion. (720 aa)
SERK1Somatic embryogenesis receptor kinase 1; Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Phosphorylates BRI1 on 'Ser-887' and CDC48 on at least one threonine residue and on 'Ser-41'. Confers embryogenic competence. Acts redundantly with SERK2 as a control point for sporophytic development controlling male gametophyte production. Involved in the brassinolide signaling pathway. (625 aa)
BAK1BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1; Dual specificity kinase acting on both serine/threonine- and tyrosine-containing substrates. Controls the expression of genes associated with innate immunity in the absence of pathogens or elicitors. Involved in brassinosteroid (BR) signal transduction. Phosphorylates BRI1. May be involved in changing the equilibrium between plasma membrane-located BRI1 homodimers and endocytosed BRI1- BAK1 heterodimers. Interaction with MSBP1 stimulates the endocytosis of BAK1 and suppresses brassinosteroid signaling. Acts in pathogen- associ [...] (615 aa)
MYB23Transcription factor MYB23; Transcription activator, when associated with BHLH2/EGL3/MYC146 or BHLH12/MYC1. Regulates the epidermal cell fate specification. Mediates the formation of columellae and accumulation of mucilages on seed coats. Controls the elongation of epidermal cells positively in roots but negatively in stems, leading to the promotion of primary roots elongation and repression of leaves and stems elongation, respectively. Ovoids ectopic root-hair formation, probably by inducing GL2 in roots. Controls trichome initiation and branching. (219 aa)
ACT2Actin-2; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the vegetative actins. (377 aa)
RLKLeucine-rich repeat receptor-like protein kinase. (751 aa)
CRRSP58Cysteine-rich repeat secretory protein 58. (287 aa)
THAS1Thalianol synthase; Converts oxidosqualene to thalianol. Belongs to the terpene cyclase/mutase family. (766 aa)
CYP705A5Cytochrome P450 705A5; Converts thalian-diol to a desaturated thalian-diol. Belongs to the cytochrome P450 family. (511 aa)
MRN1Marneral synthase; Converts oxidosqualene to marneral. Belongs to the terpene cyclase/mutase family. (761 aa)
PSKR2Phytosulfokine receptor 2; Phytosulfokine receptor with a serine/threonine-protein kinase activity. (1036 aa)
PSK1Phytosulfokine-alpha; Promotes plant cell differentiation, organogenesis and somatic embryogenesis as well as cell proliferation. (87 aa)
EXPA7Expansin-A7; Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found (By similarity). Belongs to the expansin family. Expansin A subfamily. (262 aa)
WERTranscription factor WER; Transcription activator, when associated with BHLH2/EGL3/MYC146 or BHLH12/MYC1. Involved in epidermal cell fate specification in roots and hypocotyl. Together with GL3 or BHLH2, promotes the formation of non-hair developing cells (atrichoblasts) et the N position in root epidermis. Regulates stomata spatial distribution in hypocotyls. Binds to the WER-binding sites (WBS) promoter regions and activates the transcription of target genes such as GL2 and of CPC. (203 aa)
PSK4Putative phytosulfokines 4; Promotes plant cell differentiation, organogenesis and somatic embryogenesis as well as cell proliferation. (87 aa)
SBT3.8Subtilisin-like protease SBT3.8. (775 aa)
SERK2Somatic embryogenesis receptor kinase 2; Serine/threonine-kinase involved in brassinosteroid-dependent and -independent signaling pathways. Acts redundantly with SERK1 as a control point for sporophytic development controlling male gametophyte production. (628 aa)
PSKR1Phytosulfokine receptor 1; Phytosulfokine receptor with both a serine/threonine-protein kinase activity and a guanylate cyclase activity. Regulates, in response to phytosulfokine binding, a signaling cascade involved in plant cell differentiation, organogenesis, somatic embryogenesis, cellular proliferation and plant growth. Involved in plant immunity, with antagonistic effects on bacterial and fungal resistances. Not involved in PSY perception. CNGC17 and AHAs form a functional cation-translocating unit that is activated by PSKR1/BAK1 and possibly other BAK1/RLK complexes. (1008 aa)
BHLH129Transcription factor bHLH129. (297 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (22%) [HD]