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CHR7 CHR7 SWI2 SWI2 SYD SYD CHR10 CHR10 CHR5 CHR5 CHR4 CHR4 PORC PORC NSP2 NSP2 SCL9 SCL9 SCL6 SCL6 SCRA SCRA PHYA PHYA GAPC1 GAPC1 PAT1-2 PAT1-2 SCL27 SCL27 PAT14 PAT14 SCL23 SCL23 UPF1 UPF1 SCL4 SCL4 GAPC2 GAPC2 PAT11 PAT11 SCL3 SCL3 SCL22 SCL22 SCL13 SCL13 SCR SCR PKL PKL SCL21 SCL21 SCL7 SCL7 NSP1 NSP1 RICE1 RICE1 RGA RGA SCL14 SCL14 DDM1 DDM1 CHR8 CHR8
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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CHR7CHD3-type chromatin-remodeling factor CHR7; Chromatin remodeling factor that represses the expression of embryonic trait genes upon and after seed germination and thus enables the developmental switch to post-germinative growth. (1202 aa)
SWI2Switch 2; May be involved in early DNA damage response (By similarity). Probable chromatin remodeling factor. (862 aa)
SYDChromatin structure-remodeling complex protein SYD; Catalytic component of the chromatin structure-remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls stem cell fate via the transcription regulation of WUS in the shoot apical meristem, by modulating its promoter. LFY-dependent repressor of the meristem identity switch from vegetative to reproductive development probably by modulating chromatin state. Involved in the regulation of floral homeotic gene expression in response to environmental stimuli. Required for carpel and ovule d [...] (3574 aa)
CHR10Probable helicase CHR10; Probable helicase-like transcription factor. (877 aa)
CHR5Protein CHROMATIN REMODELING 5; DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3.3 (By similarity). Probable chromatin remodeling factor. (1724 aa)
CHR4Protein CHROMATIN REMODELING 4; Chromatin-remodeling protein that binds DNA through histones and regulates gene transcription. May specifically recognize and bind trimethylated 'Lys-27' (H3K27me3) and non-methylated 'Lys-4' of histone H3 (By similarity). Probable chromatin remodeling factor. Belongs to the SNF2/RAD54 helicase family. (2223 aa)
PORCProtochlorophyllide reductase C, chloroplastic; Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide). (401 aa)
NSP2Nitrile-specifier protein 2; Promotes simple nitriles, but not epithionitrile or thiocyanate formation. Converts allylglucosinolate and benzylglucosinolate to their corresponding simple nitriles in the presence of myrosinase. (471 aa)
SCL9Scarecrow-like protein 9; Probable transcription factor involved in plant development. (718 aa)
SCL6Scarecrow-like protein 6; Probable transcription factor involved in plant development. (558 aa)
SCRADefensin-like protein A; Truncated and inactivated form of SCRA, a protein involved in male-mediated self-incompatibility when active. Most A.thaliana cultivars contain such an inactive form and thus, are self-fertiles. (62 aa)
PHYAPhytochrome A; Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region. Photoconversion of Pr to Pfr induces an array of morphogenetic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses. Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reduct [...] (1122 aa)
GAPC1Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic; Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3- phospho-D-glyceroyl phosphate. Essential for the maintenance of cellular ATP levels and carbohydrate metabolism. Required for full fertility. Involved in response to oxidative stress by mediating plant responses to abscisic acid (ABA) and water deficits through the activation of PLDDELTA and production of phosphatidic acid (PA), a multifunctional stress signaling lipid in plants. Associates with FBA6 to [...] (338 aa)
PAT1-2Protein PAT1 homolog; Activator of mRNA decapping. Involved in mRNA decay via decapping. Involved in disease resistance in response to biotrophic and necrotrophic pathogens. Is part of a signaling pathway including MPK4 and the disease resistance protein SUMM2. (793 aa)
SCL27Scarecrow-like protein 27; Probable transcription factor involved in plant development. (640 aa)
PAT14Probable protein S-acyltransferase 14; Palmitoyl acyltransferase; Belongs to the DHHC palmitoyltransferase family. (307 aa)
SCL23Scarecrow-like protein 23; Probable transcription factor involved in plant development. (405 aa)
UPF1Regulator of nonsense transcripts 1 homolog; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (premature termination codon PTC) by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Eliminates the production of nonsense-containing RNAs (ncRNAs). Required for plant development and adaptation to environmental stresses, including plant defense and response to wounding. Belongs to the DNA2/NAM7 helicase family. (1254 aa)
SCL4Scarecrow-like protein 4; Probable transcription factor involved in plant development. Belongs to the GRAS family. (584 aa)
GAPC2Glyceraldehyde-3-phosphate dehydrogenase GAPC2, cytosolic; Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3- phospho-D-glyceroyl phosphate. Essential for the maintenance of cellular ATP levels and carbohydrate metabolism (By similarity). Binds DNA in vitro. (338 aa)
PAT11Protein S-acyltransferase 11; S-acyltransferase involved in protein lipid modification. Belongs to the DHHC palmitoyltransferase family. (345 aa)
SCL3Scarecrow-like protein 3; Probable transcription factor involved in plant development. (482 aa)
SCL22Scarecrow-like protein 22; Probable transcription factor involved in plant development. (623 aa)
SCL13Scarecrow-like protein 13; Probable transcription factor that acts as a positive regulator of continuous red light signals downstream of phytochrome B (phyB). Required for the regulation of hypocotyl elongation during de- etiolation. May be required to modulate phytochrome A (phyA) signal transduction in a phyB-independent way. (529 aa)
SCRProtein SCARECROW; Transcription factor required for quiescent center cells specification and maintenance of surrounding stem cells, and for the asymmetric cell division involved in radial pattern formation in roots. Essential for cell division but not differentiation of the ground tissue. Also required for normal shoot gravitropism. Regulates the radial organization of the shoot axial organs. Binds to the promoter of MGP, NUC, RLK and SCL3. Restricts SHR movment and sequesters it into the nucleus of the endodermis. Belongs to the GRAS family. (653 aa)
PKLCHD3-type chromatin-remodeling factor PICKLE; Chromatin remodeling factor that represses the expression of embryonic trait genes (such as NFYB9/LEC1) upon and after seed germination and thus enables the developmental switch to post- germinative growth. Silences some MADS-box proteins such as PHE1 and PHE2. Plays a role during carpel differentiation. Regulates late processes in cytokinin signaling. (1384 aa)
SCL21Scarecrow-like protein 21; Probable transcription factor involved in plant development. (413 aa)
SCL7Scarecrow-like protein 7; Probable transcription factor involved in plant development (Probable). Involved in environmental abiotic stress resistance. May increase the expression of stress-responsive genes (By similarity). Binds DNA in vitro (By similarity). (542 aa)
NSP1Nitrile-specifier protein 1; Responsible for constitutive and herbivore-induced simple nitrile formation. Promotes simple nitriles, but not epithionitrile or thiocyanate formation. Converts allylglucosinolate, 4- methylsulfinylbutylglucosinolate, 4-methylthiobutylglucosinolate and benzylglucosinolate to their corresponding simple nitriles in the presence of myrosinase; Belongs to the jacalin lectin family. (470 aa)
RICE1Protein RISC-INTERACTING CLEARING 3'-5' EXORIBONUCLEASE 1; 3'-to-5' exoribonuclease (RNase) specifically targeting single-stranded RNAs. Triggers miRNA accumulation in RNA-induced silencing complex (RISC), composed of miRNAs and AGO proteins, by degrading uridylated cleavage fragments. Required during plant growth and development. Belongs to the RICE family. (200 aa)
RGADELLA protein RGA; Probable transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. Probably acts by participating in large multiprotein complexes that repress transcription of GA-inducible genes. Positively regulates XERICO expression in seeds. Upon GA application, it is degraded by the proteasome, allowing the GA signaling pathway. Compared to other DELLA proteins, it is the most sensitive to GA application. No effect of the BOI proteins on its stability. Its activity is probably regulated by other phytohormones such as auxin and ethylene, attenu [...] (587 aa)
SCL14Scarecrow-like protein 14; Probable transcription factor involved in plant development. (769 aa)
DDM1ATP-dependent DNA helicase DDM1; ATP-dependent DNA helicase that plays a role in formation, organization, stability and heritability of heterochromatin and thus regulates several physiological traits. Binds to the nucleosome and promotes chromatin remodeling in an ATP-dependent manner; induces nucleosome repositioning on a short DNA fragment, and, possibly, could be guided to target sites (including silent transposable elements) by small interfering RNAs (siRNAs). Can bind both free and nucleosomal DNA. Required for the heritable maintenance of genome integrity and transcriptional gene [...] (764 aa)
CHR8Protein CHROMATIN REMODELING 8; Essential factor involved in transcription-coupled nucleotide excision repair (TCR) which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation; Belongs to the SNF2/RAD54 helicase family. (1187 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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